Technology Showcase
Discover success stories and groundbreaking innovations developed through MTEC awards and partnerships below.
See how our members are transforming ideas into lifesaving solutions.
SMART-US Wearable Ultrasound + AI Device for Muscle Force Prediction
AI-powered ultrasound in a wearable—SMART-US delivers lab-grade muscle-force insights anywhere.
Published on July 14, 2025
BiomX Achieves Positive Phase 2 Results for BX211 in Treating Diabetic Foot Osteomyelitis
BiomX has reported positive Phase 2 results for BX211, its personalized phage therapy for Diabetic Foot Osteomyelitis (DFO). The treatment significantly improved ulcer healing, showing promise for reducing amputation risk. Supported by NMRC and MTEC, BX211 may offer new hope for both military and civilian patients.
Published on June 16, 2025
Accelerating a Disposable-free Blood Warmer Prototype through FDA Clearance
With MTEC support, Delta Development Team advanced its Single Unit Blood Warmer (SUBW)—a battery-powered, field-ready device—for FDA 510(k) clearance.
Published on May 13, 2025
Advancing Regenerative Medicine Manufacturing Solutions: Paving the Way for New Regenerative Medicine Products
ReMDO, in partnership with MTEC, is advancing regenerative medicine manufacturing through industry-driven programs. Key efforts include developing universal cell media and tunable bioinks for 3D bioprinting. These innovations aim to standardize processes and support the production of next-generation therapies for both military and civilian healthcare applications.
Published on May 13, 2025
A Noninvasive, Portable Solution for On-the-Spot Detection and Continuous Monitoring of Concussions and Strokes
With support from USAMRMC and MTEC, researchers have developed SCISCCO—a portable, noninvasive system using infrared spectroscopy to simultaneously monitor brain metabolism and hemodynamics. It shows promise for diagnosing and managing traumatic brain injury and internal bleeding in military and civilian settings, offering real-time insights to guide treatment and improve patient outcomes.
Published on May 12, 2025
Sana Health publishes first peer-reviewed article exploring the effectiveness of Sana device in managing PTSD in MTEC/MOMRP/VA study
Researchers found that combining the Sana Device with standard PTSD treatments significantly improved symptoms, anxiety, depression, and quality of life in veterans, outperforming treatment alone. This non-invasive, drug-free technology offers a promising mental health tool. A $3.4M follow-up study is underway, with broader trials and FDA approval efforts in progress.
Published on May 11, 2025
Developing an Integrated Tele-Sleep Mobile Platform
The University of Maryland and military partners developed WellTap®, a tele-sleep platform using wearable tech to improve sleep care for service members. By enabling remote monitoring, mobile treatments, and virtual consultations, the project addresses sleep disorders in the military, aiming to boost Warfighter health, readiness, and system-wide care access.
Published on May 11, 2025
Therapeutic Interfering Particles (TIPs): A Single-Administration Escape-Resistant HIV Antiviral Therapy
HIV is significant threat to service members deployed overseas and a source of regional instability in areas of U.S. force protection. Deployment barriers, particularly in resource-limited settings, and the genetic diversity of HIV present major obstacles to reducing HIV prevalence using conventional therapies and potential vaccines. In response, the Weinberger Lab has developed Therapeutic Interfering Particles (TIPs) which are designed to intracellularly outcompete wild-type virus, mutate, and transmit.
Published on April 17, 2025
Astrocyte Announces Initiation of First-In-Human Phase 1 Study of the Promising Stroke and Traumatic Brain Injury Therapeutic, AST-004
Astrocyte Pharmaceuticals has begun a Phase 1 trial for AST-004, a potential treatment for stroke, TBI, and neurodegenerative diseases. The study, funded partly by MTEC and the U.S. Army, will assess safety in 52 healthy participants. If successful, it will progress to Phase 2 trials.
Published on April 4, 2025
Extracellular Matrix (ECM) Hydrogels for Regenerative Medicine Applications
Hydrogels are highly hydrated materials and can be derived from components of the extracellular matrix to facilitate immune activity and act as a scaffold for new cell growth. The Badylak Lab at the University of Pittsburgh has created lightweight, portable and temperature-tolerant hydrogels that can readily be used at the point of care in a variety of military operations, including rapid clotting for treatment of traumatic injuries on the battlefield.
Published on April 4, 2025
Assessment of Psychological and Physiological Effects of Augmented Reality
Augmented reality (AR) is rapidly being adopted by the military for medical training. However, one area of concern is physiological maladaptation following prolonged AR exposure. To address this, Design Interactive developed the Dual-Adaptation Protocol for Augmented Reality (DAPAR), where they concluded that Soldiers who undergo long duration (2hr+) AR exposure will experience a reduction in sensorimotor performance for several hours, and provided recommendations for mitigating negative physiological effects during training.
Published on April 4, 2025
Development of a Novel Bacteriophage Therapeutic for Targeted Treatment of Staphylococcus aureus Bacteremia, Including Drug Resistant Forms.
Staphylococcus aureus infection is a major military health issue. Military personnel, including those on land and at sea, are at heightened risk of infection because the operational environment often involves close quarters and shared equipment for prolonged periods of time. AP-SA02, a novel bacteriophage therapeutic, is being developed by Armata Pharmaceuticals to treat military and civilian patients with S. aureus bacteremia.
Published on April 4, 2025
Electroceutical Technology Against Bacterial Drug Resistance
Bacterial drug resistance remains a significant threat to Service Members. In response, Indiana University has performed preclinical studies to establish the electroceutical based EDT technology. This technology is a flexible fabric-based disposable dressing that generates a low level of electricity in the wound milieu causing injury to the bacteria and making it more susceptible for adjunct therapies.
Published on April 4, 2025
Wearable Sensors with Novel Respiratory Biomarkers to Diagnose and Detect Early COVID-19 Using Machine Learning Algorithms
Early detection of COVID-19 and other viral diseases is a critical force readiness issue for the U.S. Armed Forces. Thus, there is an urgent need to develop wearable diagnostics to identify pre- and early symptomatic COVID-19 cases. Sibel is currently working to further validate its sensor technology and algorithm through a 300-patient study on frontline health care workers and high-risk select patients in Chicago-area hospitals.
Published on April 4, 2025
In-Field Detection of Acute Subdural Hematomas Requiring Urgent, Life-Saving Treatment in Severe TBI Patients
Traumatic acute subdural hematomas are life-threatening injuries associated with traumatic brain injuries (TBIs) that cause elevated intracranial pressure. Kitware is developing an artificial intelligence (AI)-enhanced point-of-care ultrasound (POCUS) system that is compatible with a wide range of commercial ultrasound probes. Following a TBI, the medic applies the ultrasound probe to the eye and the AI-enhanced POCUS system predicts intracranial pressure to help guide initial care and triage of wounded warfighters.
Published on April 4, 2025
Rapid Development of a Therapeutic Interfering Particle (TIP) for COVID-19
For many emerging infectious diseases, deployment challenges and pathogen mutation present major obstacles to population-level infectious disease control. In response, Therapeutic Interfering Particles (TIPs) are an emerging single-administration antiviral technology that effectively suppress viral replication, exhibit exceptionally high barriers to the evolution of antiviral resistance, and limit disease transmission. VxBiosciences and the Gladstone Institutes have teamed up to accelerate the TIPs technology through regulatory and commercialization pathways.
Published on April 4, 2025
Near Full-Body Finite Element Models to Assess Warfighter Injury Risk
Injury threats to the Warfighter will continue to evolve in future multi-domain operations. Advanced computational modeling provides a powerful approach to assess injury risk in Warfighters. SwRI has developed a computational model of the human body to, among other use cases, assess the injury risk of Behind Armor Blunt Trauma, which is a non-penetrating injury resulting from the rapid deformation of a Warfighter’s armor due to blast or blunt impact.
Published on April 4, 2025
Insight: A Micro-fabricated Neural Probe Visual Prosthesis
Recent technological advances in vision research has paved the way for potential therapeutic targets for the visually impaired. Scientific & Biomedical Microsystems (SBM) is developing a brain-machine interface called InSight as a step towards creating a visual neuroprosthesis (or “artificial vision system”) for humans to help restore, or partially restore, vision to blind patients so they can regain some form of autonomy.
Published on April 4, 2025
Applied Research Associates (ARA) Receives the 2022 MTEC Impact Award
Applied Research Associates (ARA) wins the 2022 MTEC Impact Award for developing the 4TDS system—an AI-powered, mobile decision support tool that enhances battlefield trauma care by rapidly detecting internal bleeding and shock. Co-developed with Mayo Clinic and Ambient Clinical Analytics, 4TDS improves diagnosis and treatment in austere environments using real-time vital signs.
Published on April 4, 2025
Developing an Ideal Wound Care Platform - Altrazeal Transforming Powder
ULURU Inc., supported by NAMD and MTEC, is advancing Altrazeal®, a novel wound care technology designed for extended wear in acute and chronic wounds. Altrazeal’s polymer-based powder forms a protective, oxygen-permeable matrix, reducing dressing changes and promoting healing. Already in use in civilian and veteran health systems, MTEC funding is accelerating clinical trials and expanding adoption. Additional grants support its use in military, surgical, and low-resource settings worldwide.
Published on April 4, 2025
Synthetic Training Environment for Multimodal Medical Training (STEM3T)
The U.S. military has a need for a medical synthetic training environment that combines live, virtual, constructive and gaming training modalities into a single integrated training environment. In response, Vcom3D is developing medical simulation and training systems based on plug-and-play architectures with interoperable physical and virtual patients, and treatment modules. This content, using research-based behavioral and physiological models, engages the learner in immersive game play and assesses user performance.
Published on April 4, 2025
Manufacture of a Settable Polymer Composite Bone Graft to Stabilize Fractures
Open fracture injuries are one of the largest sources of morbidity on both the battlefield and in the civilian population. The design of biomaterials that mechanically stabilize fractures while remodeling to form new bone is an unmet challenge in bone tissue engineering. Vanderbilt has designed a new bone void filler that induces bone growth, provides bone-like mechanical properties, and undergoes resorption at a rate aligned with patient biology.
Published on April 3, 2025
BurRapid Epidural Drainage Attachment for Traumatic Brain Injury
Epidural bleeding from traumatic brain injury (TBI) is immediately life-threatening and can quickly lead to brain herniation and death unless there is immediate neurosurgical intervention. BurRapid™, developed by Critical Innovations, is a medical device that provides hematoma drainage and intracranial pressure monitoring to sustain TBI patients on the battlefield. This allows for provision of these life-saving interventions earlier in the roles of care, including at the point-of-injury.
Published on April 3, 2025
Potential for Early Covid-19 detection using Fitbit devices
Early detection of COVID-19 is a critical force readiness issue for the U.S. Armed Forces. Thus, there is an urgent need to develop wearable diagnostics to identify COVID-19 cases. Fitbit is currently working to further validate its COVID-19 algorithm through a prospective study with Northwell Health utilizing Fitbit Sense and Versa 3 smartwatches. The hope is to bring wearable illness detection capabilities to its users.
Published on April 3, 2025
LifeLens Physiologic Monitoring Platform - Ascent
LifeLens Technologies is developing the Ascent Platform, which is a wearable sensor with hypoallergenic and stretchable microelectronic components and bioadhesives in an ultra‐wearable patch configuration. The device was recently demonstrated in a field-testing enviornment at the Army Expeditionary Warrior Experiment (AEWE) at Fort Benning. The actionable information obtained with the LifeLens Ascent Platform will help small unit leaders to make data-driven decisions to improve Warfighter performance and safety.
Published on April 3, 2025
Open Clinical Trial for the Evaluation of Novel Phospholipid Nanoparticles for the Treatment of Septic Shock
Vivacelle Bio was cleared by the FDA to proceed with its Phase IIa clinical trial for evaluation of the safety and efficacy of VBI-S, an intravenously injected cardiovascular support fluid containing micelles and liposomes to treat septic shock. The beneficial action of VBI-S occurs through its ability to redistribute nitric oxide, a gas that is overproduced in septic shock and causes potentially fatal low blood pressure and organ damage.
Published on April 3, 2025
Optimizing the Scalability of Evidence‐Based Behavioral Sleep Medicine Practices
NOCTEM™ has begun enrolling healthcare providers and patients for their clinical trial to evaluate a new software solution that will provide military service members with personalized insomnia treatment. NOCTEM’s new software solution aims to upskill existing providers with clinician decision support algorithms, increase their capacity to monitor service members’ sleep and compliance in real time, and deliver personalized evidence-based sleep optimization recommendations to hundreds of service members remotely.
Published on April 3, 2025
Management of Sleep and Fatigue Using the SleepTank™ Smartwatch App
Maintaining vigilance in the military operational environment and in civilian 24/7 operations requires sleep planning and management. The Institutes for Behavior Resources have begun beta testing of their smartwatch app, SleepTankTM. SleepTankTM is a proprietary sleep debt algorithm that provides military service members with long-term sleep health information and actionable recommendations for additional sleep, optimizing sleep opportunities and increasing overall sleep duration.
Published on April 3, 2025
Ultra-Rapid, Low-Cost Neutralizing Antibody Therapeutic for COVID-19
COVID-19 is a significant force readiness issue for the United States military. In response, Lumen Bioscience has started developing and testing a low-cost, orally delivered cocktail of antibodies against SARS-CoV-2 (the virus that causes COVID-19) to prevent and treat infection of the gastrointestinal tract. A gastrointestinal-targeted therapy could reduce overall viral burden, inhibit disease progression, accelerate viral clearance, and block significant transmission routes.
Published on April 3, 2025
Four-Dimensional Tactical Combat Casualty Care
The military is actively pursuing the integration of advanced simulations into their medical training regimens. 8i is creating Virtual Reality (VR) and Augmented Reality (AR) training experiences that leverage the power of volumetric video to provide a realistic training experience that mirrors real world training. The educational experiences include interactive battlefield training scenarios for improving retention, response time, and rapid decision making under pressure.
Published on April 3, 2025
Community-Engaged Research Shows Promise for Adapting Safety Interventions in Military Populations
Researchers at the University of Colorado Anschutz, supported by MOMRP and MTEC, adapted the Project Safe Guard (PSG) intervention for military populations, emphasizing peer discussions and addressing implementation challenges.
Published on March 27, 2025
MTEC Announces Awardees of 2016 Regenerative Medicine Research Projects
In partnership with the U.S. Army Medical Research & Materiel Command (USAMRMC), the Medical Technology Enterprise Consortium (MTEC) is pleased to announce the selectees in the initial round of research project awards issued under its February 29, 2016 Regenerative Medicine Request for Project Proposals. The projects listed at the bottom of this page were selected by the USAMRMC to receive funding as indicated.
Published on March 14, 2025
TBI Navigator Official Release
This innovative tool guides users through comprehensive assessment protocols, including the Glasgow Coma Scale (GCS) and the Tactical Military Acute Concussion Examination (TMACE), while also monitoring vital signs.
Published on November 21, 2024
Unify Medical’s Amplio Named TIME Best Invention of 2024
The platform technology can enable various capabilities, including surgical magnification, night vision, augmented reality, and data analytics in austere environments.
Published on November 7, 2024
Sempulse Halo Provides Real-time, Continuous, and Non-Invasive Vital Signs Data for Triage, Remote Patient Monitoring (RPM), and More
Sempulse's Halo Vital Signs Monitoring System is designed for remote, real-time monitoring and early detection of multiple subjects including hemorrhagic decompensation, a primary cause of mortality in military and civilian trauma cases.
Published on September 16, 2024
Cayuga Biotech Presents Clinical Data on Lead Product PolyP-SNP for Hemorrhage Contol
Cayuga Biotech has advanced a novel injectable clotting agent—polyP-SNP—that rapidly generates thrombin and promotes safe, targeted clotting. Promising results were presented at ISTH 2024, and a Phase 1 clinical trial is expected to begin by the end of the year.
Published on September 6, 2024
NuCress™ Factory in a Box Enables Sterile, On-demand Medical Device Production
This type of portable and automated manufacturing unit could be used in various military settings, from field hospitals to naval medical bays, enabling the on-site production of medical devices.
Published on August 13, 2024
Researchers at UCSF and UCSD Show Link Between Body Temperature and Depression
New findings support thermal interventions as potential treatments for depression.
Published on April 4, 2024
Developing a Burn Patient Transfer System to Coordinate Emergency Response between Civilian and Government Hospitals
Chenega Healthcare Services' Burn Patient Transfer System (BPTS) is now prepared for regional expansion and integration with federal transport systems.
Published on March 12, 2024
Treatment of Acute Traumatic Brain Injury (TBI) with a Novel Cytoprotective Compound
Ischemix, Inc. has demonstrated the efficacy of its lead compound, CMX-2043, a proprietary new chemical entity based on a scaffold of alpha lipoic acid.
Published on November 21, 2023
Restoring Mitochondrial Bioenergetics Following Repeated Mild Blast-induced TBI
Researchers at the University of Kentucky demonstrated that the novel drug MP201 mitigates mitochondrial dysfunction following mbTBI.
Published on September 6, 2023
Hardware and Software Platforms for High-density Next Generation Neural Recording and Stimulation
Scientific & Biomedical Microsystems has developed next-generation neural interface technology for brain-computer interfaces (BCIs), including a visual prosthesis system, with wide-ranging applications in neuroprosthetics and neuromodulation for military and clinical use.
Published on July 5, 2023
COAST: A Clinician-centered Digital Tool to Monitor and Treat Patients in Real-Time
With support from USAMRMC and MTEC, NOCTEM has developed digital platforms for monitoring and treating sleep disturbances in military settings.
Published on June 20, 2023
Humacyte's Universally Implantable, Bioengineered Tissues Treat Injured in Ukraine
In March 2022, Ukrainian surgeons began requesting the "HAVs" for distribution to hospitals to treat patients with injuries including shrapnel wounds and mine blast injuries.
Published on November 29, 2022
Novel 3D Printed, Single-Use, and Scalable Cell Expansion Bioreactor – Advanced Development and Demonstration in a Clinical Cell Manufacturing Environment
The SwRI® bioreactor is a 3D printed, single-use, and scalable cell manufacturing system that provides a large cell culture surface with a relatively small footprint.
Published on October 20, 2022
JETS: Empowering Clinical Team Synergy
With support from DHA and MTEC, IVIR’s JETS program enables fully integrated, multi-echelon clinical simulation training by digitally linking diverse medical and tactical simulators for enhanced, realistic patient care training.
Published on October 6, 2022
Development of a Universal Bioreactor Platform for Regenerative Medicine Clinical Manufacturing
ReMDO is developing a universal, modular bioreactor platform to streamline and scale the production of regenerative medicine therapies.
Published on September 1, 2022
Developing a Self-administered, Fast-acting Inhaled Immunotherapy for COVID-19
Inhalon Biopharma and Celltrion's lead candidate, IN-006, has shown safety and prolonged lung retention in Phase 1 trials, offering a self-administered, fast-acting solution for COVID-19 and other viral threats.
Published on August 15, 2022
Leveraging Wearable Ring Data for Early SARS-CoV-2 Detection
UCSF, UCSD, and MIT-LL have developed an algorithm using Oura Ring data to detect COVID-19 symptoms up to 2.75 days before testing, improving early illness intervention.
Published on August 3, 2022
Mobile System for Trauma Assessment Training (MSTAT)
Charles River Analytics is developing MSTAT, a mobile trauma assessment training app that uses virtual patients to provide accessible, realistic, and TCCC-guided practice for military medical personnel.
Published on August 31, 2021
MTEC Presents Annual Awards at the 6th Annual Membership Meeting
The virtual four-day conference focused on accelerating modernization to enable multi-domain operations.
Published on April 2, 2021
Centivax’s Novel Engineered Antibody Neutralizes Pandemic Coronaviruses and has been Engineered for Enhanced Therapeutic Properties
With support from MTEC, Centivax has rapidly developed a potent antibody therapeutic for COVID-19 in under nine weeks. Engineered for safety, stability, and field deployment, the treatment has completed preclinical studies and is advancing toward clinical trials to address both military and civilian healthcare needs.
Published on January 14, 2021
Clinical Trial for Use of a Wearable Diagnostic for Very Early Symptomatic Detection of COVID-19 Infection is Now Actively Recruiting
With funding from MTEC and USAMRDC, Philips North America is leading a partnership to evaluate a wearable device for early COVID-19 detection. The study uses BioIntelliSense’s BioSticker to monitor vital signs in 2,500 participants, aiming to secure Emergency Use Authorization for rapid, noninvasive diagnostics.
Published on December 23, 2020
Reduction of HIV Prevalence and Incidence Using TIPs: Single-administration, Escape-Resistant Antivirals for Resource-limited Settings
TIPs reduce HIV by 100-fold in mice, show broad efficacy and safety, and resist mutation.
Published on November 30, 2020
The Arizona State University MEDLOG Project – A Roadmap to Industry Best Practice (IBP)
This two-year project aimed to help DHA Medical Logistics (MEDLOG) enhance performance and service quality by reducing logistics variability at the point of care to inform the transition to LogiCole.
Published on November 15, 2020
Humacyte’s Bioengineered Blood Vessel Implanted by Clinicians at Walter Reed to Restore Blood Circulation to Veteran’s Leg
Humacyte has bioengineered human acellular vessels (HAVs) that regenerate into living tissue, offering a groundbreaking vascular solution for military and civilian patients.
Published on November 1, 2020
MTEC Awardee Advances Medical Simulation
In September 2020, soldiers and reservists used AUGMED during a Combat Lifesaver Course to enhance readiness for performing lifesaving interventions under stress.
Published on October 5, 2020
Universal Media Supports Cells Derived from 10 Different Tissue Types
ReMDO's initiative aims to reduce FDA regulatory hurdles by creating standardized media and procedures for expanding diverse human cell types across all three germ layers.
Published on September 3, 2020
COVID-19: A Global Issue, a Shared Goal
MTEC is investing over $50 million to combat COVID-19 through wearable tech, home-based therapeutics, and tele-critical care solutions.
Published on May 28, 2020
AI-enhanced System for Detecting Severe Traumatic Brain Injury (TBI)
Kitware Inc. and Duke University are developing an AI-powered diagnostic system to rapidly detect severe TBI.
Published on April 8, 2020
MTEC Honored GenCure and Critical Innovations with the 2020 MTEC Prototype of the Year Awards at the 5th Annual MTEC Membership Meeting
GenCure and Critical Innovations have received the 2020 Prototype of the Year Awards.
Published on March 6, 2020
Congratulations to Adaptive Phage Therapeutics for a New Award: “Development of Personalized Bacteriophage Therapeutic for the Treatment of Bacterial Infections”
Adaptive Phage Therapeutics will evaluate the human safety and efficacy of a novel bacteriophage prototype for the treatment of bacterial infections. The goal is to evaluate its safety and efficacy for FDA approval.
Published on January 24, 2020
Congratulations to the University of Pittsburgh for their MTEC award: “Enhanced Biologic Scaffold for Volumetric Muscle Loss”
Building on promising human study results, the University of Pittsburgh team will assess clinical efficacy and explore alternative antibiotic coatings in preclinical models to enhance muscle regeneration.
Published on August 2, 2019
Remodeling of Nanocomposite Bone Cements in a Rabbit Femoral Condyle Defect Model
The design of biomaterials that mechanically stabilize fractures while remodeling to form new bone is an unmet challenge in bone tissue engineering.
Published on July 23, 2019
SpherIngenics Completes MTEC Prototype Acceleration Award to Develop a Platform for the Treatment of Infected Wounds
The project is now ready to advance into large animal proof-of-concept studies as the next step toward regulatory application.
Published on May 2, 2019
MTEC Recognizes Two Projects for the Prototype of the Year Awards at Annual Membership Meeting
The Prototype of the Year Awards honored University of Texas at Arlington/ReHeal for a novel wound dressing and Humacyte, Inc. for a human acellular vessel.
Published on April 2, 2019
Human Biomed Advances Prototype Development of Extracorporeal Life Support (ECLS) Devices
The team has recently demonstrated in vivo proof of concept of an extracorporeal life support (ECLS) device to simultaneously replace impaired lung and kidney functions.
Published on March 2, 2019