Technology Showcase
Discover success stories and groundbreaking innovations developed through MTEC awards and partnerships below.
See how our members are transforming ideas into lifesaving solutions.
Cayuga Biotech Presents Clinical Data on Lead Product PolyP-SNP for Hemorrhage Contol
Cayuga Biotech, supported by MTEC and the Combat Casualty Care Research Program, developed a polyphosphate silica nanoparticle (polyP-SNP) that accelerates clotting without causing off-target clots. Presented at ISTH 2024, the injectable drug targets non-compressible hemorrhages and enters Phase 1 trials in 2024. It shows promise for emergency bleeding interventions.
Published on May 19, 2025
Accelerating a Disposable-free Blood Warmer Prototype through FDA Clearance
With MTEC support, Delta Development Team advanced its Single Unit Blood Warmer (SUBW)—a battery-powered, field-ready device—for FDA 510(k) clearance.
Published on May 13, 2025
Advancing Regenerative Medicine Manufacturing Solutions: Paving the Way for New Regenerative Medicine Products
ReMDO, in partnership with MTEC, is advancing regenerative medicine manufacturing through industry-driven programs. Key efforts include developing universal cell media and tunable bioinks for 3D bioprinting. These innovations aim to standardize processes and support the production of next-generation therapies for both military and civilian healthcare applications.
Published on May 13, 2025
A Noninvasive, Portable Solution for On-the-Spot Detection and Continuous Monitoring of Concussions and Strokes
With support from USAMRMC and MTEC, researchers have developed SCISCCO—a portable, noninvasive system using infrared spectroscopy to simultaneously monitor brain metabolism and hemodynamics. It shows promise for diagnosing and managing traumatic brain injury and internal bleeding in military and civilian settings, offering real-time insights to guide treatment and improve patient outcomes.
Published on May 12, 2025
Sana Health publishes first peer-reviewed article exploring the effectiveness of Sana device in managing PTSD in MTEC/MOMRP/VA study
Researchers found that combining the Sana Device with standard PTSD treatments significantly improved symptoms, anxiety, depression, and quality of life in veterans, outperforming treatment alone. This non-invasive, drug-free technology offers a promising mental health tool. A $3.4M follow-up study is underway, with broader trials and FDA approval efforts in progress.
Published on May 11, 2025
Developing an Integrated Tele-Sleep Mobile Platform
The University of Maryland and military partners developed WellTap®, a tele-sleep platform using wearable tech to improve sleep care for service members. By enabling remote monitoring, mobile treatments, and virtual consultations, the project addresses sleep disorders in the military, aiming to boost Warfighter health, readiness, and system-wide care access.
Published on May 11, 2025
Therapeutic Interfering Particles (TIPs): A Single-Administration Escape-Resistant HIV Antiviral Therapy
HIV is significant threat to service members deployed overseas and a source of regional instability in areas of U.S. force protection. Deployment barriers, particularly in resource-limited settings, and the genetic diversity of HIV present major obstacles to reducing HIV prevalence using conventional therapies and potential vaccines. In response, the Weinberger Lab has developed Therapeutic Interfering Particles (TIPs) which are designed to intracellularly outcompete wild-type virus, mutate, and transmit.
Published on April 17, 2025
Astrocyte Announces Initiation of First-In-Human Phase 1 Study of the Promising Stroke and Traumatic Brain Injury Therapeutic, AST-004
Astrocyte Pharmaceuticals has begun a Phase 1 trial for AST-004, a potential treatment for stroke, TBI, and neurodegenerative diseases. The study, funded partly by MTEC and the U.S. Army, will assess safety in 52 healthy participants. If successful, it will progress to Phase 2 trials.
Published on April 4, 2025
Extracellular Matrix (ECM) Hydrogels for Regenerative Medicine Applications
Hydrogels are highly hydrated materials and can be derived from components of the extracellular matrix to facilitate immune activity and act as a scaffold for new cell growth. The Badylak Lab at the University of Pittsburgh has created lightweight, portable and temperature-tolerant hydrogels that can readily be used at the point of care in a variety of military operations, including rapid clotting for treatment of traumatic injuries on the battlefield.
Published on April 4, 2025
Assessment of Psychological and Physiological Effects of Augmented Reality
Augmented reality (AR) is rapidly being adopted by the military for medical training. However, one area of concern is physiological maladaptation following prolonged AR exposure. To address this, Design Interactive developed the Dual-Adaptation Protocol for Augmented Reality (DAPAR), where they concluded that Soldiers who undergo long duration (2hr+) AR exposure will experience a reduction in sensorimotor performance for several hours, and provided recommendations for mitigating negative physiological effects during training.
Published on April 4, 2025
Development of a Novel Bacteriophage Therapeutic for Targeted Treatment of Staphylococcus aureus Bacteremia, Including Drug Resistant Forms.
Staphylococcus aureus infection is a major military health issue. Military personnel, including those on land and at sea, are at heightened risk of infection because the operational environment often involves close quarters and shared equipment for prolonged periods of time. AP-SA02, a novel bacteriophage therapeutic, is being developed by Armata Pharmaceuticals to treat military and civilian patients with S. aureus bacteremia.
Published on April 4, 2025
Electroceutical Technology Against Bacterial Drug Resistance
Bacterial drug resistance remains a significant threat to Service Members. In response, Indiana University has performed preclinical studies to establish the electroceutical based EDT technology. This technology is a flexible fabric-based disposable dressing that generates a low level of electricity in the wound milieu causing injury to the bacteria and making it more susceptible for adjunct therapies.
Published on April 4, 2025
Wearable Sensors with Novel Respiratory Biomarkers to Diagnose and Detect Early COVID-19 Using Machine Learning Algorithms
Early detection of COVID-19 and other viral diseases is a critical force readiness issue for the U.S. Armed Forces. Thus, there is an urgent need to develop wearable diagnostics to identify pre- and early symptomatic COVID-19 cases. Sibel is currently working to further validate its sensor technology and algorithm through a 300-patient study on frontline health care workers and high-risk select patients in Chicago-area hospitals.
Published on April 4, 2025
In-Field Detection of Acute Subdural Hematomas Requiring Urgent, Life-Saving Treatment in Severe TBI Patients
Traumatic acute subdural hematomas are life-threatening injuries associated with traumatic brain injuries (TBIs) that cause elevated intracranial pressure. Kitware is developing an artificial intelligence (AI)-enhanced point-of-care ultrasound (POCUS) system that is compatible with a wide range of commercial ultrasound probes. Following a TBI, the medic applies the ultrasound probe to the eye and the AI-enhanced POCUS system predicts intracranial pressure to help guide initial care and triage of wounded warfighters.
Published on April 4, 2025
Leveraging Wearable Ring Data for Early SARS-CoV-2 Detection
Researchers from UCSF, UCSD, and MIT-LL, with support from USAMRDC and MTEC, developed an algorithm using Oura Ring data for early COVID-19 detection. Analyzing 63,153 participants, the algorithm identified symptoms 2.75 days before testing. The study also linked post-vaccine elevated temperature to stronger antibody responses. This research advances wearable health monitoring, benefiting both military and civilian populations by enabling early illness detection and improved pandemic response strategies.
Published on April 4, 2025
Rapid Development of a Therapeutic Interfering Particle (TIP) for COVID-19
For many emerging infectious diseases, deployment challenges and pathogen mutation present major obstacles to population-level infectious disease control. In response, Therapeutic Interfering Particles (TIPs) are an emerging single-administration antiviral technology that effectively suppress viral replication, exhibit exceptionally high barriers to the evolution of antiviral resistance, and limit disease transmission. VxBiosciences and the Gladstone Institutes have teamed up to accelerate the TIPs technology through regulatory and commercialization pathways.
Published on April 4, 2025
Near Full-Body Finite Element Models to Assess Warfighter Injury Risk
Injury threats to the Warfighter will continue to evolve in future multi-domain operations. Advanced computational modeling provides a powerful approach to assess injury risk in Warfighters. SwRI has developed a computational model of the human body to, among other use cases, assess the injury risk of Behind Armor Blunt Trauma, which is a non-penetrating injury resulting from the rapid deformation of a Warfighter’s armor due to blast or blunt impact.
Published on April 4, 2025
Insight: A Micro-fabricated Neural Probe Visual Prosthesis
Recent technological advances in vision research has paved the way for potential therapeutic targets for the visually impaired. Scientific & Biomedical Microsystems (SBM) is developing a brain-machine interface called InSight as a step towards creating a visual neuroprosthesis (or “artificial vision system”) for humans to help restore, or partially restore, vision to blind patients so they can regain some form of autonomy.
Published on April 4, 2025
Applied Research Associates (ARA) Receives the 2022 MTEC Impact Award
Applied Research Associates (ARA) wins the 2022 MTEC Impact Award for developing the 4TDS system—an AI-powered, mobile decision support tool that enhances battlefield trauma care by rapidly detecting internal bleeding and shock. Co-developed with Mayo Clinic and Ambient Clinical Analytics, 4TDS improves diagnosis and treatment in austere environments using real-time vital signs.
Published on April 4, 2025
Developing an Ideal Wound Care Platform - Altrazeal Transforming Powder
ULURU Inc., supported by NAMD and MTEC, is advancing Altrazeal®, a novel wound care technology designed for extended wear in acute and chronic wounds. Altrazeal’s polymer-based powder forms a protective, oxygen-permeable matrix, reducing dressing changes and promoting healing. Already in use in civilian and veteran health systems, MTEC funding is accelerating clinical trials and expanding adoption. Additional grants support its use in military, surgical, and low-resource settings worldwide.
Published on April 4, 2025
Synthetic Training Environment for Multimodal Medical Training (STEM3T)
The U.S. military has a need for a medical synthetic training environment that combines live, virtual, constructive and gaming training modalities into a single integrated training environment. In response, Vcom3D is developing medical simulation and training systems based on plug-and-play architectures with interoperable physical and virtual patients, and treatment modules. This content, using research-based behavioral and physiological models, engages the learner in immersive game play and assesses user performance.
Published on April 4, 2025
Manufacture of a Settable Polymer Composite Bone Graft to Stabilize Fractures
Open fracture injuries are one of the largest sources of morbidity on both the battlefield and in the civilian population. The design of biomaterials that mechanically stabilize fractures while remodeling to form new bone is an unmet challenge in bone tissue engineering. Vanderbilt has designed a new bone void filler that induces bone growth, provides bone-like mechanical properties, and undergoes resorption at a rate aligned with patient biology.
Published on April 3, 2025
BurRapid Epidural Drainage Attachment for Traumatic Brain Injury
Epidural bleeding from traumatic brain injury (TBI) is immediately life-threatening and can quickly lead to brain herniation and death unless there is immediate neurosurgical intervention. BurRapid™, developed by Critical Innovations, is a medical device that provides hematoma drainage and intracranial pressure monitoring to sustain TBI patients on the battlefield. This allows for provision of these life-saving interventions earlier in the roles of care, including at the point-of-injury.
Published on April 3, 2025
Potential for Early Covid-19 detection using Fitbit devices
Early detection of COVID-19 is a critical force readiness issue for the U.S. Armed Forces. Thus, there is an urgent need to develop wearable diagnostics to identify COVID-19 cases. Fitbit is currently working to further validate its COVID-19 algorithm through a prospective study with Northwell Health utilizing Fitbit Sense and Versa 3 smartwatches. The hope is to bring wearable illness detection capabilities to its users.
Published on April 3, 2025
LifeLens Physiologic Monitoring Platform - Ascent
LifeLens Technologies is developing the Ascent Platform, which is a wearable sensor with hypoallergenic and stretchable microelectronic components and bioadhesives in an ultra‐wearable patch configuration. The device was recently demonstrated in a field-testing enviornment at the Army Expeditionary Warrior Experiment (AEWE) at Fort Benning. The actionable information obtained with the LifeLens Ascent Platform will help small unit leaders to make data-driven decisions to improve Warfighter performance and safety.
Published on April 3, 2025
Open Clinical Trial for the Evaluation of Novel Phospholipid Nanoparticles for the Treatment of Septic Shock
Vivacelle Bio was cleared by the FDA to proceed with its Phase IIa clinical trial for evaluation of the safety and efficacy of VBI-S, an intravenously injected cardiovascular support fluid containing micelles and liposomes to treat septic shock. The beneficial action of VBI-S occurs through its ability to redistribute nitric oxide, a gas that is overproduced in septic shock and causes potentially fatal low blood pressure and organ damage.
Published on April 3, 2025
Optimizing the Scalability of Evidence‐Based Behavioral Sleep Medicine Practices
NOCTEM™ has begun enrolling healthcare providers and patients for their clinical trial to evaluate a new software solution that will provide military service members with personalized insomnia treatment. NOCTEM’s new software solution aims to upskill existing providers with clinician decision support algorithms, increase their capacity to monitor service members’ sleep and compliance in real time, and deliver personalized evidence-based sleep optimization recommendations to hundreds of service members remotely.
Published on April 3, 2025
Management of Sleep and Fatigue Using the SleepTank™ Smartwatch App
Maintaining vigilance in the military operational environment and in civilian 24/7 operations requires sleep planning and management. The Institutes for Behavior Resources have begun beta testing of their smartwatch app, SleepTankTM. SleepTankTM is a proprietary sleep debt algorithm that provides military service members with long-term sleep health information and actionable recommendations for additional sleep, optimizing sleep opportunities and increasing overall sleep duration.
Published on April 3, 2025
Ultra-Rapid, Low-Cost Neutralizing Antibody Therapeutic for COVID-19
COVID-19 is a significant force readiness issue for the United States military. In response, Lumen Bioscience has started developing and testing a low-cost, orally delivered cocktail of antibodies against SARS-CoV-2 (the virus that causes COVID-19) to prevent and treat infection of the gastrointestinal tract. A gastrointestinal-targeted therapy could reduce overall viral burden, inhibit disease progression, accelerate viral clearance, and block significant transmission routes.
Published on April 3, 2025
Four-Dimensional Tactical Combat Casualty Care
The military is actively pursuing the integration of advanced simulations into their medical training regimens. 8i is creating Virtual Reality (VR) and Augmented Reality (AR) training experiences that leverage the power of volumetric video to provide a realistic training experience that mirrors real world training. The educational experiences include interactive battlefield training scenarios for improving retention, response time, and rapid decision making under pressure.
Published on April 3, 2025
Community-Engaged Research Shows Promise for Adapting Safety Interventions in Military Populations
Researchers at the University of Colorado Anschutz, supported by MOMRP and MTEC, adapted the Project Safe Guard (PSG) intervention for military populations, emphasizing peer discussions and addressing implementation challenges.
Published on March 27, 2025
MTEC Announces Awardees of 2016 Regenerative Medicine Research Projects
In partnership with the U.S. Army Medical Research & Materiel Command (USAMRMC), the Medical Technology Enterprise Consortium (MTEC) is pleased to announce the selectees in the initial round of research project awards issued under its February 29, 2016 Regenerative Medicine Request for Project Proposals. The projects listed at the bottom of this page were selected by the USAMRMC to receive funding as indicated.
Published on March 14, 2025