MTEC Announces Awardees of 2016 Regenerative Medicine Research Projects

The technology area being investigated is the development of large scale manufacturing and quality control of Regenerative Medicine – based products. The specific goal of this project is to make adult human mesenchymal stem cells manufactured without the use of animal products (i.e. “xeno-free” stem cells) widely available.

This will be accomplished by leveraging the partners’ complementary technologies and processes, and adapting, optimizing and validating them for use in xeno-free microcarrier-based bioreactors of increasing capacity (500 mL → 3-5 Liters → 40-80 Liters). These efforts will yield manufacturing technologies capable of producing commercial-scale, Current Good Manufacturing Practices (cGMP)-compliant stem cells. These cells will benefit both military and civilian regenerative medicine applications by accelerating clinical translation of cell therapies and tissue engineering technologies.