Profusa, Inc.
Profusa, Inc. is a pioneering digital health company based in the San Francisco Bay Area, dedicated to making the body’s chemistry easily accessible to improve health and wellness. Profusa develops tissue-integrating biosensors for continuous, real-time monitoring of body chemistries, empowering individuals and clinicians with actionable, medical-grade data to transform personal health management and disease prevention. Their unique bioengineering approach overcomes the foreign body response, enabling long-term, in-body monitoring through tiny, flexible biosensors that become one with the body. Profusa’s technology platform supports both consumer and medical applications, with a vision to revolutionize personalized medicine and digital health. The company is supported by significant grant funding from agencies such as DARPA and NIH, and collaborates with leading academic, hospital, and industry partners worldwide.
Industries
Nr. of Employees
medium (51-250)
Patents
Optical filter device, system, and methods for improved optical rejection of high angle of incidence (AOI) light
2025-01-21 • US-12204125-B2
View Details
Optical filter device, system, and methods for improved optical rejection of high angle of incidence (AOI) light
2025-01-21 • US-12204125-B2
View DetailsProducts
Implantable tissue oxygen monitoring system (CE-marked, wearable reader option)
Integrated system comprising an injectable tissue-integrating optical hydrogel sensor, delivery injector, external optical interrogation hardware (handheld, console, or adhesive wireless patch), and software for continuous measurement of subcutaneous tissue oxygen with secure mobile/cloud connectivity.
Research multi-analyte implantable sensing platform
Development platform consisting of tissue-integrating sensor scaffolds and interoperable reader systems designed to support continuous measurement of multiple biochemical analytes (oxygen, glucose, lactate, ions, pH) for preclinical and clinical research.
Implantable tissue oxygen monitoring system (CE-marked, wearable reader option)
Integrated system comprising an injectable tissue-integrating optical hydrogel sensor, delivery injector, external optical interrogation hardware (handheld, console, or adhesive wireless patch), and software for continuous measurement of subcutaneous tissue oxygen with secure mobile/cloud connectivity.
Research multi-analyte implantable sensing platform
Development platform consisting of tissue-integrating sensor scaffolds and interoperable reader systems designed to support continuous measurement of multiple biochemical analytes (oxygen, glucose, lactate, ions, pH) for preclinical and clinical research.
Expertise Areas
- Continuous biochemical monitoring
- Tissue-integrated biosensor development
- Optical sensing and tissue optics
- Clinical trial design and execution for implantable devices
Key Technologies
- Fluorescence and phosphorescence optical sensing
- Phosphorescence lifetime (time-resolved) measurement
- Tissue-integrating hydrogel microfiber scaffolds
- Injectable micro‑fiber implants (hypodermic delivery)
Key People
News & Updates
Profusa received the prestigious Edison Silver Award for its tissue-integrating biosensors enabling long-term continuous monitoring of body chemistry.
Awarded for real-time body chemistry monitoring and innovation in the biochemical sensors market.
Article discusses the promise of Profusa’s microsensing technology for monitoring microvascular perfusion and oxygen supply in tissue, especially for patients with chronic limb-threatening ischemia.
Describes Profusa’s tissue-integrated biosensors that overcome the foreign body response and stream data to mobile devices for personal and medical use.
IEEE Spectrum article on Profusa’s injectable biosensors as the next generation of body sensing technology beyond wearables.
Healthline article on Profusa’s Lumee biosensor, a universal sensor for continuous monitoring of body chemistry stats including glucose and oxygen.
Profusa received the prestigious Edison Silver Award for its tissue-integrating biosensors enabling long-term continuous monitoring of body chemistry.
Awarded for real-time body chemistry monitoring and innovation in the biochemical sensors market.
Article discusses the promise of Profusa’s microsensing technology for monitoring microvascular perfusion and oxygen supply in tissue, especially for patients with chronic limb-threatening ischemia.
Describes Profusa’s tissue-integrated biosensors that overcome the foreign body response and stream data to mobile devices for personal and medical use.
IEEE Spectrum article on Profusa’s injectable biosensors as the next generation of body sensing technology beyond wearables.
Healthline article on Profusa’s Lumee biosensor, a universal sensor for continuous monitoring of body chemistry stats including glucose and oxygen.