C2Sense, Inc.


Developer of diagnostic hardware and algorithmic methods that apply computer vision and physics-informed algorithms to improve sensitivity and specificity of point-of-care and at-home assays. Founded as an MIT spinout, the company develops connected reader hardware, AI-enhanced image analysis, luminescent materials and multiplex molecular detection methods and collaborates with diagnostic and pharmaceutical partners.

Industries

N/A

Nr. of Employees

small (1-50)


Patents

Luminescence imaging for sensing and/or authentication

US-12385835-B2

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Temporal sensing and related methods

US-11994518-B2

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Systems and methods for determining a characteristic of an emissive species

US-11796539-B2

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Luminescence imaging for sensing and/or authentication

US-11726037-B2

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Gas sensing identification

US-11726093-B2

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Systems and methods for sensing using consumer electronic devices

US-11662346-B2

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Products

Low-cost connected diagnostic reader for rapid assays

A network-connected reader system intended to acquire assay images and apply algorithmic processing to boost sensitivity and specificity of rapid diagnostic tests.

Multiplex detection method for circulating tumor and cell-free DNA

An R&D-stage multiplex molecular detection capability focused on enhanced detection of circulating tumor DNA and cell-free DNA.

Helios™

A rapid molecular diagnostic platform with unparalleled multiplexed detection and single-copy sensitivity, harnessing padlock probe chemistry, isothermal amplification, and optical readout to detect hundreds to thousands of targets simultaneously.

HALO®

Enables identification of false positives, delineation of non-specific binding, and mitigation of assay defects to improve assay performance without redesign.


Services

Custom development and deployment of image-analysis and physics-based algorithms to improve assay performance without assay redesign.

Design and integration of low-cost, network-connected reader hardware for rapid diagnostic assays and connected workflows.

Joint R&D programs to develop and validate multiplex detection methods for circulating tumor DNA and cell-free DNA.

Expertise Areas

  • Digital diagnostics and connected readers
  • Assay signal enhancement and optimization
  • Luminescence-based sensing and time-gated measurements
  • Point-of-care and at-home diagnostic systems
  • Show More (4)

Key Technologies

  • Computer vision for image analysis
  • Physics-informed signal processing algorithms
  • AI-enhanced diagnostic analytics
  • Connected reader hardware and cloud integration
  • Show More (4)

News & Updates

Licensing agreement to commercialize an on-dose authentication (anti-counterfeiting) technology for solid oral dosage pharmaceutical and nutraceutical products.

Announcement of Dr. Kevin Ban joining the company's board as a strategic advisor effective June 1, 2024.

Announcement of Dr. Michael Mina joining the board as an independent director effective May 24, 2024.

Announcement that the company and Princeton BioMeditech received a second NIH RADx award to support development of a digitally-connected at-home diagnostic reader and multiplex antigen test solution.

Peer-reviewed paper demonstrating smartphone-based luminescence imaging as a tool for time-gated measurements.

Awarded NIH RADx Tech funding to accelerate commercialization of a connected at-home diagnostic reader for sensitivity enhancement of an over-the-counter COVID-19/Flu antigen rapid test.

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