Antibiotic Resistance
Antibiotic resistance (AMR) threatens combat casualty care, prolonged field care and force readiness. This capability spans rapid molecular and phenotypic diagnostics, anti-biofilm modalities, novel therapeutics (phage, peptides, adjuvants) and stewardship-informed surveillance to prevent and treat multidrug-resistant infections in austere environments.
Technical Challenges
Rapid, deployable susceptibility testing to guide targeted therapy at point-of-injury or in prolonged field care.
Biofilms on wounds, implants, and indwelling devices that shield pathogens from antibiotics and immune response.
Limited therapeutic options against MDR/XDR pathogens and slow clinical translation of novel antibacterials.
Surveillance gaps and delayed detection of resistance patterns in distributed, austere settings.
Emerging Opportunities
Compact, robust point-of-care tests that deliver actionable susceptibility data within hours.
Adjunct anti-biofilm agents and device coatings validated for battlefield wounds and implants.
Validated treatment algorithms and logistic pathways for stewardship during delayed evacuation or prolonged care.
Integrated, secure surveillance platforms linking forward units, hospitals, and public health to detect emergent resistance.
Current and Emerging Technologies in Antibiotic Resistance
Rapid molecular and phenotypic diagnostics
CRISPR-based, PCR, isothermal assays and microfluidic culture systems that identify pathogens and resistance genes quickly at point-of-care to guide targeted therapy and limit empiric broad-spectrum use.
Point-of-care antimicrobial susceptibility testing (AST)
Portable phenotypic AST platforms and rapid growth-based sensors that provide MIC or categorical susceptibility within hours rather than days, enabling appropriate antibiotic selection in austere settings.
Anti-biofilm strategies and device technologies
Enzymatic dispersal agents, anti-adhesive coatings, localized delivery systems and combination therapies that disrupt biofilms on wounds, catheters and implants to restore antibiotic efficacy.
Novel therapeutics and adjuncts
Bacteriophage, antimicrobial peptides, bacteriocins, antibiotic adjuvants and host-directed therapies that broaden activity against MDR pathogens and reduce selection pressure for resistance.
Surveillance, stewardship and analytics
Cloud- and edge-enabled genomic epidemiology, AI-driven stewardship decision support and secure data-sharing platforms to detect trends, optimize empiric therapy, and inform logistics in distributed care.
Importance to Military Medicine
Combat casualty care
Severe blast and polytrauma wounds are prone to MDR infections; rapid identification and targeted therapy reduce morbidity and amputation risk.
Prolonged and delayed evacuation
When evacuation is delayed, optimized diagnostics, adjunct therapeutics and stewardship protocols are essential to manage infections in far-forward, resource-limited settings.
Austere environments and force readiness
Maintaining operational readiness requires preventing outbreaks, preserving effective antibiotic stocks, and minimizing recovery time from infectious complications.
Medical logistics and supply resilience
Optimized diagnostics and targeted therapy reduce unnecessary broad-spectrum use and shelf-burden, improving supply chain efficiency in deployed settings.
Alignment with the MTEC Mission
Directly supports MTEC's DoD-focused mission to accelerate biomedical solutions that protect Warfighters from infectious threats and preserve force readiness.
Leverages multidisciplinary MTEC portfolio—diagnostics, therapeutics, regenerative medicine and prolonged care—to translate laboratory innovations into field-ready capabilities.
Enables public–private collaboration and rapid prototyping pathways prioritized by MTEC for technologies with direct military and civilian benefit.
Supports DoD outbreak preparedness and biodefense by integrating surveillance, rapid response therapeutics, and stewardship into deployment medicine.
Dual-Use (Military + Civilian) Applications
Dual-use diagnostics and therapeutics protect military personnel and translate to civilian hospitals and public health systems confronting MDR pathogens.
Point-of-care AST and surveillance platforms developed for deployed care streamline clinical workflows in rural and resource-limited civilian settings.
Anti-biofilm coatings and localized delivery systems reduce device-associated infections across military and civilian trauma care and surgical implants.
Surveillance analytics and stewardship decision support have civilian public health value for outbreak detection, antimicrobial policy, and hospital infection control.
Explore MTEC Members with Antibiotic Resistance Capabilities
MTEC members—industry, academia and medical innovators—bring rapid prototyping, clinical trial networks, regulatory expertise and DoD partnerships to accelerate translation of AMR solutions into operational use.
Explore member profiles to partner on rapid diagnostics, anti-biofilm technologies, novel therapeutics and surveillance platforms that directly address military and civilian unmet needs.
92 Members with Antibiotic Resistance capabilities.
Georgia Southern University is a vibrant institution with over 26,100 students across three campuses in Statesboro, Savannah, and Hinesville. The university offers 132 degree programs at the associate, bachelor’s, master’s, and doctorate levels, emphasizing student success, community impact, and research excellence. With a commitment to inclusivity and engagement, Georgia Southern fosters a supportive environment for diverse learners, including military-affiliated and adult students. The university is dedicated to transforming lives through education and community engagement, aligning its programs with regional needs. Additionally, Georgia Southern provides accelerated pathways for students to fast-track their master's degrees, enhancing educational opportunities. The university also emphasizes career readiness and public impact research, preparing students for successful careers and contributing to community development.
Volatylix, a Cambridge, MA based startup, is dedicated to early diagnosis enabling timely and appropriate treatment benefiting the patient, physician, provider and payor. Our patent pending platform – DECIPHER – and unique detection sensor technology – OFIS - combine to identify various disease states and conditions via proprietary breath biomarkers, volatile organic compounds (VOC’s). DECIPHER is disease agnostic and will speed diagnosis, while improving accuracy over currently available diagnostic methods. The tests use a noninvasive 4-minute breath sample with analysis taking ~15 minutes on our portable, battery powered platform. Initial products include fungal pneumonias, lung cancer (staging, monitoring, differential diagnosis and screening) and C. difficile.
FiteBac Technology/FiteBac Pharma's K21 uniquely targets the underlying disease state, given that most diseases involve microbial-associated inflammation and mitochondrial dysfunction. FiteBac Technology innovations stem from the work of numerous international academic research scientists. FiteBac Pharma K21 is the blockbuster antimicrobial small molecule designed to modulate biological, immunological, and metabolic systems for treating a wide range of infectious and inflammatory diseases. This patented drug substance has demonstrated the ability to safely eliminate bacterial, fungal, and viral infections, enhance innate immunity, induce mitophagy while improving mitochondrial and cellular metabolism, accelerate wound healing, and even promote the development of zebrafish and chickens, leading to increased adult mass. Rigorous research from Dr. Bhupesh Prusty's laboratory and Dr Christopher Rongo's laboratory is focused on various aspects of mitochondrial remodeling and reprograming, as well as mitochondrial-to-nuclear signaling with K21.
Armata Pharmaceuticals, Inc. is a clinical-stage biotechnology company dedicated to developing pathogen-specific bacteriophage therapeutics to combat antibiotic-resistant and difficult-to-treat bacterial infections. With a focus on addressing the global antibiotic resistance crisis, Armata leverages its proprietary bacteriophage-based technology to develop high-impact, best-in-class phage therapeutics. The company operates from a 56,000 square foot facility in Los Angeles, California, equipped for phage product development from bench to clinic. Armata's team of microbiologists and scientists work on discovering natural phages and enhancing them through synthetic biology and engineering to create tailored drug products for clinical trials.
Auburn University Research & Economic Development is dedicated to advancing research and economic growth through a collaborative effort among its various colleges and departments. The organization focuses on fostering innovation, supporting faculty and student research, and facilitating partnerships with industry and government to address societal challenges and enhance the quality of life. Recent initiatives include the launch of the Team Science Series to promote interdisciplinary collaboration and the development of the Gulf Coast Engineering Research Station to address coastal environmental challenges.
The Institute for Integrative & Innovative Research (I3R) at the University of Arkansas is dedicated to pioneering solutions to complex societal challenges through convergence research. With a mission to advance research excellence and stimulate economic development, I3R focuses on deploying innovations at scale through collaboration across various sectors, including academia, industry, and government.
The University of Chicago is a prestigious urban research university committed to rigorous inquiry and intellectual freedom. Founded in 1890, it has produced numerous Nobel laureates and is known for its transformative education and groundbreaking research across various fields. The university fosters an inclusive and diverse learning environment, encouraging participation from all community members.
Memsel is a biotechnology research and development company dedicated to enhancing health and combatting infections through advanced phage therapies and targeted delivery systems. The company aims to transform healthcare solutions across human, animal, and plant domains, addressing critical health challenges and antibiotic resistance.
Boston University is a major research institution committed to leading breakthroughs across various disciplines. The Office of Research supports and advances research excellence, fostering collaboration among researchers, industry partners, and government leaders to address significant societal challenges.
Baylor University is a preeminent Christian research university committed to addressing the world's most meaningful challenges through top-tier research and scholarship. Recognized as an R1 research institution, Baylor focuses on infusing its distinct Christian mission into its research initiatives, fostering a commitment to excellence and innovation.
Evimero is an interdisciplinary company focused on understanding the interactions between microorganisms and human health, agriculture, and the environment, utilizing Systems Biology and AI/ML. Evimero applies molecular principles to infectious disease and microbiome science to improve health outcomes and environmental sustainability through targeted interventions in dysbiotic microbiomes and in people with infectious disorders. Evimero has an infectious disease product pipeline including both prophylactic and diagnostic assets against common causes of Travelers' Diarrhea, including a unique approach to preventing infection with human Norovirus, enterotoxigenic E. coli (ETEC) and others. Evimero's pipeline of drugs targeting human and animal microbiomes includes early-stage assets aimed at generalized microbiome-driven inflammation and gut leak, and specific disease-targeted disorders including Parkinson Disease and Inflammatory Bowel Diseases. Evimero's platform also makes possible a suite of point-of-care diagnostics that can be used for patient cohorting (infectious diseases), risk stratification, and ultimately informing therapeutic decision-making. The nature of Evimero's platform assures a steady stream of novel assets targeting both infectious diseases and chronic disorders with roots in microbiome dysfunction.
NEXT Labs is pioneering the automation and accessibility of next-generation sequencing (NGS) by developing affordable, portable solutions for sample and library preparation. Their mission is to enable sequencing anywhere, by anyone, moving NGS from specialized labs to point-of-need applications. By automating complex sample processing steps, NEXT Labs aims to democratize genomics research and diagnostics, making advanced testing faster, more accessible, and cost-effective for a wide range of applications including infectious disease detection, cancer, and neurodegenerative disease diagnostics.
Kane Biotech is a Canadian-based biotechnology company focused on the research, development, and commercialization of products that prevent and remove microbial biofilms. Established in 2001, the company aims to improve human and animal welfare through innovative solutions to biofilm-related challenges and antimicrobial resistance. With a strong portfolio of 54 patents and patents pending, Kane Biotech is recognized as a leader in biofilm research and technology, and is listed on the TSX Venture Exchange under the symbol 'KNE' and on the OTC Markets under the symbol 'KNBIF'.
Base Pair Biotechnologies specializes in custom aptamer discovery and development for research, diagnostics, therapeutics, and industrial applications. The company leverages proprietary multiplex selection, advanced bioinformatics, and chemical modification techniques to develop high-affinity and selective nucleic acid aptamers. Base Pair enables affinity reagent development, biosensor design, and molecular detection for a broad range of targets and partners across academia and industry.
The Nanovaccine Institute, established at Iowa State University in 2017, is a national transdisciplinary research consortium focused on advancing nano-based technologies to treat and prevent diseases. The institute aims to revolutionize public health outcomes through the design and promotion of nano-based vaccines and therapeutics.
Policy Wisdom, LLC is a global public health policy consulting firm founded in 2010, dedicated to delivering evidence-based solutions that positively impact public health worldwide. With a mission to be a benchmark of excellence in health policy, Policy Wisdom partners with governments, NGOs, pharmaceutical companies, and advocacy groups in over 150 countries. The company leverages a 100% virtual business model and a diverse, expert team to provide innovative methodologies and client-centered strategies. Their work spans policy strategy development, capacity building, evidence generation, and the creation of educational resources, all aimed at measurable improvements in health systems and equitable health outcomes. Policy Wisdom is recognized for its leadership in decolonizing global health, advancing precision medicine, and shaping policies that address both emerging and persistent public health challenges across the globe.
Solventum is a healthcare company dedicated to enabling better, smarter, and safer healthcare solutions. With a legacy of innovation, Solventum focuses on improving patient outcomes through advanced medical technologies, oral care solutions, health information technology, and purification and filtration systems.
Immuron Ltd is a publicly listed Australian biopharmaceutical company focused on developing and commercializing a novel class of specifically targeted polyclonal antibodies. The company aims to address significant unmet medical needs, particularly in treating gastrointestinal disorders caused by pathogenic bacteria. Immuron has established partnerships with leading research institutions and companies to enhance its product development and manufacturing capabilities. The company is currently advancing its drug candidates through clinical development, targeting conditions such as Campylobacteriosis, recurrent Clostridiodes difficile infections, and travelers’ diarrhea. Immuron is also engaged in various scientific studies and collaborations to further its research and product efficacy. The company has a proprietary technology platform and is committed to transforming treatment paradigms for gastrointestinal health.
The University of Maryland, Baltimore (UMB) is Maryland’s public health, law, and human services university. It is dedicated to improving the human condition and serving the public good through education, research, clinical care, and service. UMB is the founding campus of the University System of Maryland and offers a wide range of professional degrees in health care, human services, and law.
The University of North Carolina Wilmington (UNCW) is a top doctoral and research institution located in Wilmington, North Carolina. Established in 1947, UNCW has grown to serve nearly 18,000 students and employs about 2,500 staff. The university is dedicated to providing a powerful academic experience that fosters creative inquiry, critical thinking, and thoughtful expression in a beautiful coastal setting. UNCW is committed to educational excellence, community engagement, and global connections, making it a vibrant part of the southeastern North Carolina community. UNCW also emphasizes the importance of freedom of expression and mutual respect within its diverse community.
The University of Missouri-Kansas City (UMKC) is dedicated to transforming today's learners into tomorrow's leaders through innovative education, research, and community engagement. With over 125 academic programs, UMKC fosters a diverse and inclusive environment that empowers students to achieve their goals and make a positive impact in their communities.
Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world, dedicated to providing high-quality, patient-centered care. With a history of innovation spanning nearly 150 years, Mayo Clinic is committed to transforming healthcare through research, education, and compassionate care, ensuring that the best possible treatment is available to everyone.
Temple University is Philadelphia’s only public university and a global center of academic excellence. It is classified as an R1 institution, indicating very high research activity, and offers over 600 academic programs across 17 diverse schools and colleges. The university is committed to providing accessible education that fosters positive change and prepares students to become leaders in their fields. Additionally, Temple emphasizes a vibrant campus life enriched by arts, culture, and a commitment to diversity and inclusivity. The university also promotes a tobacco-free environment to enhance the health and well-being of its community. Temple's athletics program further enhances student life, with 19 varsity teams competing at the NCAA Division I level, fostering school spirit and community engagement.
The Office of Sponsored Projects Administration (OSPA) at the University of Kentucky is dedicated to transforming tomorrow by streamlining grants and contracts. OSPA provides essential services to faculty and staff, including assistance with proposal preparation, award negotiation, and compliance with sponsor policies.
Southwest Research Institute (SwRI) is a nonprofit research and development organization that provides independent, premier services to government and industry clients. Founded in 1947, SwRI is committed to advancing science and technology to benefit humanity, focusing on innovative solutions that improve human health and safety. With a diverse range of technical divisions, SwRI addresses complex challenges in various fields including mechanical engineering, materials, aerospace, automotive, biomedical, and more.
Cepheid is a global leader in molecular diagnostics, dedicated to improving healthcare by developing, manufacturing, and marketing automated, easy-to-use molecular systems and tests. Their mission is to provide rapid, accurate, and actionable genetic testing for a wide range of infectious diseases, oncology, and human genetics. Cepheid's flagship GeneXpert System delivers scalable, sample-to-answer PCR testing for institutions of any size, supporting both centralized and decentralized care. The company is committed to expanding access to high-quality diagnostics worldwide, supporting public health initiatives, driving innovation in molecular testing, and advancing sustainability and responsible business practices.
AvantGuard has developed a novel broad-spectrum, bio-compatible antiseptic that is proven in in vitro, ex vivo, and in vivo testing to be safe and more effective than topical antibiotics, while also effective as a liquid sterilant or disinfectant. Our compound, Avantamine, can be packaged as a heat-tolerant, long-shelf-life powder in a metal foil packet that dissolves rapidly in potable water to make either a solution or hydrogel. At a high concentration, Avantamine's non-hazardous, non-corrosive solution will sterilize medical equipment in 10 minutes and is safe enough for instruments to be removed and used without rinsing. Diluted by half, Avant24 at 0.6% concentration is (1) an antiseptic for washing wounds or treating cutaneous bacterial and fungal infections, (2) a high-level disinfectant for a variety of medical devices without corroding metals or degrading plastics, and (3) a disinfectant for surfaces in the surgical suite. At 6X further dilution, Avant24 can treat trench mouth. At another 3X dilution, Avant24 can be added to water to make it drinkable. There are an enormous number of potential uses and the only difference between them is the amount of diluent, in this case water, used to prepare the solution. Our military focus areas are (1) low resource sterilization of medial devices, (2) fungal treatment for burn wounds, and (3) a prophylactic for infection control in a self-administered Role 1 environment with the powder applied directly to a wound. Our commercial focus area is Candida auris decolonization which is not currently possible with any other antiseptic. We have definitive animal testing to show efficacy and superiority to chlorhexidine and are moving toward the clinic.
The University of Arizona Applied Research Corporation (UA-ARC) is a non-profit organization affiliated with the University of Arizona, dedicated to leveraging the university's strengths in research and education to address national security challenges. UA-ARC aims to deliver innovative solutions and foster collaborations between academia, industry, and government.
The University of Utah (UU) is a leading research institution recognized for its research activity and commitment to innovation and discovery. As an R1 Institution, it is dedicated to advancing knowledge and solving critical problems that challenge our national security interests and impact the global community. We foster interdisciplinary collaboration and provide resources to drive transformative research focused on enhancing medical care superiority for the U.S. Department of Defense (DoD) through advanced medical and engineering research sponsored by our Applied Medical & Engineering Laboratory (AM&E Lab). As a leading public university, UU also provides healthcare services to seven states in the Intermountain West, with the largest catchment of remote and austere frontier territory for any academic center. Leveraging its geographic advantage, technological and commercialization strengths, expertise in medical services, and leading-edge, core engineering competencies, UU is uniquely positioned to address the nation's critical national security interests.
Lixa is a biotech company dedicated to resolving recurring microbial infections and contaminations by addressing the global challenge of antimicrobial resistance (AMR). The company is pioneering a technology platform called NeoX™, which aims to restore the effectiveness of existing antimicrobials and biocides against resistant bacteria. Lixa's mission is to develop scalable, cost-effective solutions that can be applied across various sectors, including human, animal, plant, marine, and industrial applications, to combat AMR and improve global health.
The Institute for Biohealth Innovation (IBI) at George Mason University unites over 300 faculty and thousands of students across 34 departments to advance human health and well-being through innovative research. The IBI focuses on major health challenges, including infectious diseases, cancer, brain and behavior, and cardiovascular health, collaborating with national and international partners to implement solutions that enhance health outcomes.
Microbiotix, Inc. is a clinical stage biopharmaceutical company dedicated to the discovery and development of proprietary small molecule drugs targeting serious infectious diseases, including multi-drug resistant pathogens. The company is recognized for its innovation and has consistently been a top recipient of NIH awards among Massachusetts biotech/pharma companies.
The University of Minnesota's Research and Innovation Office (RIO) serves as a central resource for conducting, managing, and sponsoring research. It aims to facilitate collaborative research that addresses complex problems and promotes innovations that improve lives. RIO oversees research compliance and administration, fostering a culture of integrity and ethical practices in research. Additionally, RIO is committed to enhancing research capacity through various funding opportunities and strategic initiatives, including the management of specialized facilities for biocontainment research.
The University of Notre Dame, founded in 1842, is a prestigious Catholic research university located in South Bend, Indiana. It is dedicated to providing a holistic education that integrates faith, reason, and service to others. The university aims to be a leading global Catholic research institution, fostering a community of scholars committed to inquiry, justice, and the common good.
New York University (NYU) is a global university that connects talented and ambitious individuals in some of the world's greatest cities. Its mission is to be a top-quality institution, providing a diverse range of academic programs and opportunities for students to engage with the world's challenges. NYU is committed to fostering innovation and entrepreneurship, and it emphasizes diversity, equity, and inclusion in its educational mission. Founded in 1831, NYU has evolved to become a leader in higher education, with a commitment to accessibility and a diverse student body. NYU offers a wide array of academic programs, including accelerated studies and online education, catering to the needs of a global student population.
The Wyss Institute for Biologically Inspired Engineering uses biological design principles to develop new engineering innovations that will transform medicine and create a more sustainable world. At the Wyss Institute, we leverage recent insights into how Nature builds, controls and manufactures to develop new engineering innovations - a new field of research we call Biologically Inspired Engineering. By emulating biological principles of self assembly, organization and regulation, we are developing disruptive technology solutions for healthcare, energy, architecture, robotics, and manufacturing, which are translated into commercial products and therapies through formation of new startups and corporate alliances.
ATD Emolda has been delivering innovative solutions for 40 years, specializing in the conversion and manufacturing of components and assemblies for industrial, medical, and pharmaceutical applications. The company has become a thought leader in advanced wound care materials, focusing on developing high-performance polyurethane foams and silicone adhesives.
Northwestern University is a prestigious institution dedicated to fostering a diverse and inclusive environment, promoting academic excellence, and engaging in impactful research. With campuses in Evanston, Chicago, and Doha, Qatar, Northwestern emphasizes global engagement and community involvement, preparing students to tackle complex challenges through interdisciplinary collaboration and innovative thinking.
The University of Iowa is dedicated to providing a comprehensive educational experience that fosters academic excellence, research opportunities, and a vibrant student life. With a commitment to accessibility and inclusivity, the university aims to prepare its students for success in various fields while promoting a supportive community.
Case Western Reserve University is dedicated to solving the biggest issues of today and tomorrow through innovative research and education. With a commitment to experiential learning, the university offers a wide range of programs and opportunities for students to engage in research, internships, and community service, all within a vibrant campus located in Cleveland, Ohio.
The University of Alaska Fairbanks (UAF) is a Land, Sea, and Space Grant university and an international center for research, education, and the arts, emphasizing the circumpolar North and its diverse peoples. UAF integrates teaching, research, and public service as it educates students for active citizenship and prepares them for lifelong learning and careers.
Singletto is a biotechnology company revolutionizing antimicrobial protection for healthcare, military, industry, and consumer applications. Their core technology, Oxafence®, leverages Antimicrobial Photodynamic Inactivation (aPDI) using light-activated dyes to generate singlet oxygen, which inactivates viruses and bacteria on treated surfaces. Founded during the COVID-19 pandemic by Drs. James Chen and Thomas Lendvay, Singletto's mission is to deliver ongoing, science-driven Active Protection™ against current and emerging biological threats. The company collaborates with global health leaders, including the WHO and CDC, and partners with manufacturers to develop and commercialize innovative products that actively destroy pathogens during use. Singletto's work is validated by a robust body of peer-reviewed research and ongoing global collaborations.
New Jersey Institute of Technology (NJIT) is a leading public research university dedicated to providing students with a world-class education in STEM fields and beyond. With a commitment to academic excellence, NJIT prepares students to be leaders in the most in-demand fields through innovative programs, expert faculty, and extensive research opportunities. NJIT is recognized for its affordability and return on investment, making it a top choice for students seeking a quality education. NJIT is also ranked among the top public universities in the nation, known for its diverse student body and commitment to fostering an inclusive environment.
Spectral Platforms is pioneering rapid diagnostic solutions in clinical microbiology, focusing on eliminating time-consuming steps in traditional microbiology to enable faster, more accurate detection and characterization of pathogens. Their proprietary technology leverages sensitive detection of bacterial metabolites and redox state changes, providing results in minutes rather than days. The company aims to improve patient outcomes, particularly in sepsis and infectious disease management, by delivering rapid, reliable, and actionable diagnostic information. Spectral Platforms also offers advanced microbiology services and collaborates with leading institutions and regulatory bodies to validate and deploy their innovations.
The University of Arkansas for Medical Sciences Office of Research and Sponsored Programs (ORSP) is dedicated to supporting UAMS faculty in acquiring, performing, and administering projects funded by external sources. The ORSP ensures compliance with policies, negotiates award terms, liaises between investigators and sponsors, and manages subcontracts.
Founded by Thomas Jefferson in 1819, the University of Virginia is a prestigious public university that emphasizes the advancement of human knowledge, education of leaders, and cultivation of an informed citizenry. It is recognized for its commitment to academic excellence, vibrant student life, and a strong alumni network, making it one of the top public universities in the United States.
The University of Missouri is dedicated to advancing research, innovation, and impact through a comprehensive support system for faculty, students, and staff. It aims to foster collaboration, enhance economic development, and promote entrepreneurship, while ensuring compliance with research regulations and ethical standards. The university also emphasizes the importance of interdisciplinary partnerships and provides resources to support veteran entrepreneurs through programs like the Entrepreneurship Bootcamp for Veterans.
The University of Massachusetts Lowell (UML) is dedicated to providing a comprehensive educational experience that prepares students for success in their careers and lives. With over 200 degree programs and a commitment to research and community engagement, UML fosters a vibrant learning environment for its diverse student body.
Microbion Corp is a clinical-stage pharmaceutical company focused on developing a novel class of compounds to treat difficult-to-treat infections, including chronic and antibiotic-resistant infections. Their lead therapeutic candidate, Pravibismane, is a groundbreaking anti-infective drug with broad-spectrum activity and a unique mechanism that halts microbial cellular metabolism. The company is committed to providing physicians with innovative options to improve and extend patients' lives, addressing key unmet medical needs with their site-specific delivery approach that enhances efficacy and safety while reducing antibiotic resistance risks.
Aphios is a green biotechnology company focused on developing enabling nanotechnology platforms and enhanced therapeutics for health maintenance, disease prevention, and treatment of various conditions including cancers, infectious diseases, and central nervous system (CNS) disorders. The company emphasizes environmentally-sustainable practices and aims to improve the quality of life through innovative therapies.
The University of Nebraska Medical Center (UNMC) is dedicated to transforming lives through premier educational programs, innovative research, and extraordinary patient care. Founded in 1869, UNMC is a leader in health sciences education and research, serving as a vital resource for Nebraska and beyond.
The University of Georgia (UGA) is dedicated to facilitating instruction, scholarly and creative activity, and research collaborations across disciplines. UGA is a leader in research-based products and innovation, significantly impacting the state of Georgia and beyond through its extensive research initiatives and academic programs.
Southern Research (SR) is a nonprofit preclinical contract research institute that has been bridging basic science and commercial solutions for over 80 years. From pioneering chemotherapy research in collaboration with Memorial Sloan Kettering to generating millions of data points in the global fight against COVID-19, SR has consistently been at the forefront of scientific innovation. Our team of experts excels in transforming cutting-edge science into tangible societal benefits, utilizing comprehensive drug discovery and development capabilities to drive innovation and advance life-saving medical breakthroughs. SR collaborates with over 100 industrial partners, the federal government, and numerous academic institutions to advance the development of life-saving medicines.
Phare Bio is a social venture dedicated to addressing the urgent global threat of antibiotic resistance through innovative AI and deep learning technologies. The company aims to revolutionize antibiotic discovery and development, ensuring that new antibiotics reach those in greatest need.
MassBiologics, part of UMass Chan Medical School, is the only nonprofit, FDA-licensed manufacturer of vaccines and biologics in the United States. With over 100 years of experience, it is dedicated to improving public health through the research, development, and production of biologic products, including vaccines and monoclonal antibodies.
The Medical University of South Carolina (MUSC) is South Carolina’s premier biomedical research institution, dedicated to advancing health through innovative research, education, and clinical care. With over $300 million in research funding and a commitment to addressing pressing health challenges, MUSC fosters collaboration among faculty, staff, and community partners to translate scientific discoveries into impactful health solutions. The South Carolina Clinical & Translational Research Institute (SCTR) at MUSC supports innovative research across the translational spectrum, from basic science to population health, including patient-centered and community-engaged research.
The UCI Office of Research is dedicated to supporting and enhancing the creative and scholarly activities of UCI faculty and researchers. It provides central administrative support for research programs, ensuring compliance with regulations and fostering an environment conducive to research and innovation.
The Clemson University Research Foundation (CURF) is dedicated to advancing the research enterprise at Clemson University by connecting faculty and students with industry partners. CURF facilitates the commercialization of university technologies, supports research collaboration, and promotes innovation through various funding and support programs.
Virginia Tech is a leading research institution dedicated to improving the quality of life and the human condition through education, research, and community engagement. With a commitment to its motto, 'Ut Prosim' (That I May Serve), Virginia Tech fosters a collaborative environment that integrates technology into all disciplines, preparing scholars to be leaders and problem-solvers.
Radiatric Inc. is dedicated to developing and commercializing innovative technologies to improve outcomes for patients with blood stream infections that can lead to sepsis, and septic shock. Antimicrobial resistance is a serious global health threat. Our flagship medical device, our RAD-01 system, is an extracorporeal non-antibiotic device designed to treat blood stream infections by targeting and killing pathogens even multi drug-resistant organisms. The company's focus is on non-pharmacological methods of killing pathogens, aiming to reduce the mortality and long-term effects associated with sepsis.
Clyra Medical Technologies is a healthcare company dedicated to improving lives by developing and commercializing innovative products for wound and skin infection treatment. As a subsidiary of BioLargo, Inc., Clyra focuses on creating safe, effective, and cost-efficient solutions that reduce the need for antibiotics and promote wound healing. Their technology, based on a copper-iodine complex, offers a broad-spectrum antimicrobial effect without known microbial resistance, making it suitable for various healthcare settings.
LSU Health Sciences Center New Orleans is dedicated to educating future health professionals and scientists, advancing research, and providing exceptional healthcare. With six professional schools and numerous affiliated hospitals, LSUHSC-NO aims to improve health outcomes and address health equity challenges in Louisiana.
MRIGlobal is a renowned Midwest research institute based in Kansas City, dedicated to improving the overall health, safety, and well-being of people everywhere. With over 80 years of experience, MRIGlobal specializes in diagnostics, pharmaceutical sciences, vaccines and therapeutics, global health surveillance, infectious disease, public health, warfighter protection, agriculture, and management and operations. The organization is committed to using science and technology to create solutions for a safer, healthier, and more sustainable world.
Biomeme is dedicated to advancing global health through innovative molecular detection technologies. Their mission is to provide rapid, reliable diagnostics that empower healthcare providers and researchers to make informed decisions in real-time, ultimately improving patient outcomes and public health responses. Biomeme emphasizes the importance of One Health, recognizing the interconnectedness of human, animal, and environmental health. They are at the forefront of combating antibiotic resistance through multifaceted approaches, including Host Response research, testing, and robust advocacy initiatives. Additionally, Biomeme fosters a culture of innovation and creativity, empowering its team to develop novel solutions for global health challenges.
Biophoundry specializes in advancing scalable engineered phage-based solutions for therapeutics, diagnostics, and bio-molecular engineering. It is shifting the paradigm from phage discovery to phage design. Its team leverages expertise in synthetic biology, machine learning, and data science to accelerate the development of precision antibiotics and address critical healthcare challenges such as antimicrobial resistance.
Northeastern University is a global research university founded in 1898, renowned for its experiential learning model, high-impact research, and deep partnerships. The university emphasizes innovative teaching and research that engage students, faculty, and alumni in solving real-world problems, fostering a dynamic and inclusive community across its 13 campuses worldwide.
The University of Montana (UM) is a flagship public research university located in Missoula, Montana. Established in 1893, UM offers a wide range of undergraduate and graduate programs, emphasizing research, creativity, and community engagement. With a commitment to academic excellence and public service, UM aims to transform lives through education and research, fostering a diverse and inclusive environment for its students.
CMTx Biotech, Inc. is an emerging biopharmaceutical company working to develop and commercialize host-directed therapeutics for the treatment of inflammatory and infectious diseases, as well as threat-agnostic medical countermeasures against high-priority chemical, biological, radiological and nuclear (CBRN) threats to homeland security and national defense. Our lead drug candidate is a clinically-tested, highly-stable, orally-administered small molecule that has been shown to improve survival and prevent lung injury in a wide variety of animal models of sepsis, acute respiratory distress syndrome (ARDS) and multiple organ dysfunction syndrome (MODS) across several species, including mice, rats, hamsters, pigs and sheep. Having already secured approximately $4M in funding to-date, including $3.6M in NIH SBIR/STTR grants, we are actively seeking non-dilutive funding, private investment capital and/or an established strategic partner to help advance human clinical trials and FDA Animal Rule development, as well as to expand our product pipeline.
The University at Buffalo is a leading public research university and flagship of the SUNY System, recognized for its innovative research and commitment to societal impact. It aims to transform scientific and technological breakthroughs into global impact, addressing complex challenges through interdisciplinary collaboration.
Principle Diagnostics is a state-of-the-art clinical and anatomic pathology laboratory founded in 2015, specializing in toxicology, molecular, and genetic testing. Licensed in over 40 states and led by an executive team with over 50 years of cumulative experience, Principle Diagnostics is committed to operational efficiency, adaptive innovation, and personalized service. The company serves a diverse clientele—including individuals, medical facilities, and research organizations—across sectors such as pain management, substance abuse, podiatry, urology, long-term care, memory care, and assisted living. Principle Diagnostics aims to be a leader in diagnostic services by continuously expanding its comprehensive test menu and upholding values of integrity, service, excellence, and innovation. The company is recognized for its strong focus on compliance, financial integrity, and the integration of advanced therapeutic management and antibiotic stewardship programs. Principle Diagnostics is also celebrated for its commitment to ethical principles, teamwork, and inspired people, striving to set an example in the industry for trust, credibility, and patient-focused outcomes. In 2024, Principle Diagnostics celebrated a decade of pioneering advancements in pharmacogenomic (PGx) testing, further cementing its role as an innovation leader in personalized medicine.
UC San Francisco is a leading university dedicated to advancing health worldwide through preeminent biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. With a commitment to public service, UCSF aims to innovate health care approaches for vulnerable populations and train the next generation of health professionals.
Calla Lily Clinical Care develops patented medical device technologies engineered to improve intravaginal drug delivery for women's health, focusing on clinical needs such as fertility support, pregnancy management, prevention of recurrent miscarriage, and restoration of the vaginal microbiome. Recognized for innovation, the company maintains collaborative partnerships with clinical and academic institutions and secures funding to advance clinical trials and R&D. Their technology is designed for leak prevention, convenience, and dosing confidence, with a strong commitment to sustainability and social impact as a certified B-Corporation.
SUNY Upstate Medical University is a leading academic medical center in Central New York, dedicated to providing exceptional patient care, advancing medical research, and educating future healthcare professionals. As the region's only Level I trauma center and a Magnet recognized institution, Upstate is committed to delivering cutting-edge, life-saving treatments and fostering a compassionate, patient-centered environment. The university also plays a significant role in the community through outreach programs and is recognized as one of America's best large employers by Forbes.
Life Protect specializes in the design and manufacture of novel personal protective equipment (PPE), such as face masks and N95 and N99 respirators in the United States with a focus on scientific development, clinical integration, supply chain reliability, and regulatory compliance for healthcare and emergency use.
Washington State University (WSU) is a public research university dedicated to improving lives by serving the public good. With a commitment to unlocking possibilities, WSU empowers students, faculty, and others to create a world where all people can thrive. The university offers a diverse range of academic programs across its six campuses and is recognized for its high research activity and community engagement.
Northstar owns IP around the use of antibody fragments and nucleic acids to rapidly diagnose and treat bacterial and viral infections. With numerous applications to sepsis and bioterrorism countermeasure, Northstar seeks partnerships with other forward thinking companies and government entities to protect our military and enhance homeland security.
UCLA is a leading public research university located in Los Angeles, California. It is renowned for its commitment to the creation, dissemination, preservation, and application of knowledge for the advancement of global society. With a rich history of academic and athletic excellence, UCLA offers a comprehensive environment that supports both academic and personal growth. The university is dedicated to fostering innovation and making a significant impact on the world through groundbreaking research and transformative practices.
Riptide Bioscience develops engineered peptides derived from host defense peptides found widely in nature. Their focus is on creating peptide-based therapeutics for cancer, inflammatory diseases, and microbial infections, especially those resistant to conventional treatments. The company advances both preclinical and early-stage clinical programs, collaborates with academic partners and government agencies, and holds patents for its engineered peptide design technologies.
Arizona State University (ASU) is a comprehensive public research university known for its commitment to inclusivity, excellence, and societal impact. ASU is dedicated to advancing research-based solutions for global challenges, fostering strong leadership, and providing quality education accessible to all learners. The university is recognized for its innovative approach to education and its efforts in sustainability, research, and community service. ASU exemplifies a new prototype for the American public research university, focusing on excellence, broad access to quality education, and meaningful societal impact.
Advanced Light Devices manufactures the patent pending Hemealumen Polychromatic Device Innovative Solutions for Treating Infectious and Neurodegenerative Diseases Company Overview Advanced Light Devices is a pioneering company established in the early 2000s, dedicated to developing advanced medical technologies for the treatment of a range of diseases. With a vision to revolutionize healthcare, the company focuses on innovative therapies that utilize light-based technology to address complex medical challenges. The Hemealumen Polychromatic Device At the core of Advanced Light Devices' portfolio is the Hemealumen Polychromatic Device, a state-of-the-art medical tool designed to combat both viral and bacterial diseases. In addition, this device is being used as a therapeutic option for neurodegenerative disorders such as Amyotrophic Lateral Sclerosis (ALS) and Parkinson's disease. Applications in Infectious Disease Treatment The Hemealumen Polychromatic Device has demonstrated effectiveness in treating a variety of infectious diseases, including: Malaria Dengue fever COVID-19 Zika virus Shingles By utilizing targeted polychromatic light, the device disrupts the replication and survival mechanisms of pathogens, offering a non-invasive and innovative approach to disease management. Blood Treatment During Transfusions The Hemealumen Polychromatic Device is also used to treat blood during transfusions, effectively eliminating bacteria and viruses. This process enhances the safety of blood transfusions, reducing the risk of transfusion-transmitted infections and improving patient outcomes. Impact on Neurodegenerative Diseases Beyond infectious diseases, the device shows promise in the management of neurodegenerative conditions such as ALS and Parkinson's disease. Its mechanism of action may help reduce the progression of these disorders, though further research is ongoing to fully understand its therapeutic potential. Conclusion Advanced Light Devices, through the Hemealumen Polychromatic Device, is at the forefront of medical innovation. Their commitment to developing effective treatments for both infectious and neurodegenerative diseases position them as a leader in the field of light-based medical technology.
The Medical College of Wisconsin (MCW) is dedicated to transforming healthcare through innovative education, research, and patient care. With a focus on academic medicine, MCW aims to improve the health of communities by fostering a collaborative learning environment that integrates medical education with groundbreaking research and comprehensive patient care.
iGenomeDx is a San Antonio-based molecular diagnostics laboratory dedicated to providing fast, accurate, and actionable results for healthcare providers and patients. Founded by scientists with expertise in genetic research, the company leverages cutting-edge technologies such as PCR and LCMS to deliver a comprehensive menu of diagnostic services, including infectious disease detection, pharmacogenomics, genetic risk assessment, and drug monitoring. iGenomeDx's mission is to enhance clinical decision-making, improve patient care, and reduce healthcare costs through reliable and innovative laboratory solutions. The company is recognized for its commitment to quality, diversity, and community engagement, holding multiple certifications and industry awards. iGenomeDx aims to be the most trusted genetic testing and drug monitoring laboratory in San Antonio, with a vision centered on precision diagnostics, scientific integrity, and excellent customer service.
Indiana University is dedicated to building a better future through education, research, and community engagement. With a commitment to academic excellence, IU offers a diverse range of programs across its nine campuses, fostering an inclusive environment for over 90,000 students from around the world. IU is also at the forefront of groundbreaking research, particularly in areas such as brain health and Alzheimer's disease.
MyFitStrip is dedicated to enhancing oral and metabolic health through clinically-supported products that utilize the therapeutic potential of prebiotic formulations to boost nitric oxide levels. Delivered via topical oral lozenges and chewing gums, these products rapidly increase local nitric oxide concentrations to support a healthy oral microbiome and suppress pathogenic organisms in the oral and nasal cavities, which are key entry points and reservoirs for many infections, including COVID-19. By focusing on oral microbiome optimization, MyFitStrip promotes nitric oxide bioavailability, a molecule vital for vascular function, immune defense, and systemic wellness. The company's product line includes prebiotic chewing gums, slow-release lozenges, and personalized saliva test strips, all designed to support cardiovascular health, physical performance, respiratory resilience, and overall oral health.
Akthelia Pharmaceuticals is a pioneering biopharmaceutical company focused on developing therapeutics that enhance the body's innate defense mechanisms to combat debilitating diseases. The company targets mucosal barrier injury and epithelial integrity through a novel immunotherapeutic strategy. Its mission is to revolutionize treatment for diseases such as cancer, infection, and autoimmune disorders by leveraging the body's own microbial defense mechanisms.
The University of Tennessee, Knoxville is dedicated to advancing knowledge and understanding through research, scholarship, and creative work. The Office of Research, Innovation, and Economic Development supports faculty, staff, and students in developing competitive proposals and fostering a strong culture of research integrity, aiming to create a more just, prosperous, and sustainable world.
The Geneva Foundation is a 501(c)3 nonprofit established in 1993, dedicated to advancing military medicine through research, development, and education. With a commitment to ensuring optimal health for service members and the communities they serve, Geneva collaborates with various partners to drive innovative medical research and improve healthcare outcomes.
Tensentric is a contract design and manufacturing firm focused solely on medical device, in vitro diagnostic, and advanced therapy markets. We're ISO13485 certified and FDA registered to help our clients bring their new technology and products to market.
Founded in 2015, Omnix Medical is a clinical-stage biopharmaceutical company dedicated to developing novel antibiotic agents to combat infections caused by drug-resistant bacteria. Their innovative technology focuses on natural antimicrobial peptides, engineered for therapeutic use, targeting severe hospital-acquired infections and addressing the urgent threat posed by multidrug-resistant pathogens. The company is building a pipeline of first-in-class anti-infectives designed to treat severe, potentially lethal infections associated with multi-drug resistances.
Signature Science, LLC is a multidisciplinary applied science and technology company dedicated to solving the toughest forensic, biosecurity, and public health challenges. Serving both government and commercial clients, Signature Science combines scientific rigor with proven quality assurance to enhance the credibility and defensibility of programs in national security, public safety, and health security. The company is recognized for its innovation, technical excellence, and commitment to advancing the state-of-the-art in forensic science, genomics, and biosecurity technologies. Signature Science also offers advanced bioinformatics and microbiome analysis services, empowering clients with data-driven insights to address emerging threats, pandemics, and bioterrorism. The company is a subsidiary of Southwest Research Institute and is committed to community engagement and workforce development.
The Center for Military Medicine Research (CMMR) at the University of Pittsburgh is dedicated to advancing medical research for wounded service members and their families. The center focuses on trauma, emergency, and critical care, leveraging the university's strengths in medical and engineering fields, and collaborating with Carnegie Mellon University's robotics and AI expertise. CMMR aims to enhance trauma care for warfighters and civilians, contributing to the defense innovation economy.
The Texas A&M Engineering Experiment Station (TEES) is a state agency and part of the Texas A&M University System, dedicated to improving lives through engineering research, workforce development, and technology transition. TEES collaborates with industry, academia, and government to provide innovative solutions to global technical challenges.

Arizona State University
ASU Crosscutting Technologies to Enhance Military Medical Readiness and Resilience
Dr. Rachel Cassalia leads MTEC-supported efforts at ASU to shift military health from reactive care to proactive readiness through data-driven prevention.
University of Pittsburgh
Topical Metformin Lotion for Tendinopathy Prevention
University of Pittsburgh study shows topical metformin prevents overuse tendon injury. This work was sponsored through MTEC project 22-02-MPAI-014.
Theradaptive
Theradaptive’s RESTORE Trial Initiation for OsteoAdapt™ DE
Theradaptive launches RESTORE Phase I/II trial of OsteoAdapt™ DE for faster, precision bone healing in craniofacial injuries. MTEC-funded study targets improved recovery for military and civilian patients.
Altec
Autonomous Rehabilitation Device for Improved Recovery in Warfighters
The OSCIR platform—developed by Altec Inc in collaboration with the Naval Health Research Center—is bringing clinical-grade, real-time movement analysis to the front lines. Funded under MTEC-22-02-MPAI