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Base Pair Biotechnologies


Base Pair Biotechnologies specializes in custom aptamer discovery and development for research, diagnostics, therapeutics, and industrial applications. The company leverages proprietary multiplex selection, advanced bioinformatics, and chemical modification techniques to develop high-affinity and selective nucleic acid aptamers. Base Pair enables affinity reagent development, biosensor design, and molecular detection for a broad range of targets and partners across academia and industry.

Industries

biopharma
biotechnology
life-science

Nr. of Employees

small (1-50)

Base Pair Biotechnologies

8619 Broadway Street, Suite 100, Pearland, TX 77584 USA


Patents

Functional ligands to target vitamin C

2025-12-30 • US-12509716-B2

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Methods and materials for discovery of functional ligands to molecular complexes

2025-06-24 • US-12338434-B1

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Methods and materials for multiplexed collections of functional ligands

2024-04-30 • US-11970785-B2

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Functional ligands to opioids and opioid derivatives

2023-08-15 • US-11725240-B2

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Functional ligands to colistin

2023-03-21 • US-11608356-B1

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Functional ligands to drug compounds

2022-08-30 • US-11427825-B2

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Products

Catalog aptamers and reagents

Chemically synthesized oligonucleotide aptamers specific for a broad range of validated targets, available for research and diagnostic use.

DNA aptamers inhibiting vitamin C oxidation

DNA aptamers identified and validated to inhibit the oxidation of vitamin C, offering stabilization for use in food, beverages, and nutraceutical formulations.

Expertise Areas

  • Aptamer discovery and selection
  • Multiplex target binding
  • Small molecule and toxin detection
  • Molecular diagnostics development
  • Show More (8)

Key Technologies

  • SELEX (Systematic Evolution of Ligands by Exponential Enrichment)
  • Multiplex SELEX
  • Next-generation sequencing
  • Microscale thermophoresis
  • Show More (8)

Key People

Founder and Chief Scientist

General Counsel


News & Updates

Awarded a CDC grant for development of aptamers and lateral flow assays for rapid detection of synthetic opioids on surfaces.

Awarded a grant from the CDC to develop aptamer-based point-of-care tests for detection of malarial metabolites in urine and saliva.

Awarded an SBIR grant to develop aptamer-based point-of-care tests for opioids to rapidly diagnose neonatal abstinence syndrome.

Awarded a NIH SBIR contract for development and validation of non-mouse reagents for preclinical development of novel therapeutics, focusing on canine models for oncology research.

Discovery of aptamers capable of inhibiting vitamin C oxidation, with implications for food, beverages, supplements, and cosmetics.

Coverage of aptamers as alternatives to immunization and patented custom aptamer development.

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