Biophysics and Biomedical Modeling

Biophysics and biomedical modeling integrates biomechanics, cellular and tissue-scale physics, computational physiology, and machine learning to recreate injury mechanics, hemorrhage, infection dynamics, and host response. Models enable in silico trials, optimize sensor placement, predict decompensation, and support clinical decision-making in austere and prolonged-field-care settings.

Technical Challenges

  • Modeling heterogeneous polytrauma and blast biomechanics across scales from organ deformation to cellular injury.

  • Accurately predicting hemodynamic collapse and transfusion needs during delayed evacuation in austere settings.

  • Simulating host–pathogen interactions and biofilm dynamics for rapid antimicrobial decision support under antimicrobial resistance (AMR).

  • Integrating noisy, sparse physiological data from wearables and point-of-care devices into reliable real-time models.

Emerging Opportunities

  • Validated, deployable predictive models for hemorrhage control and resuscitation that work with limited inputs.

  • Standardized multiscale model validation pipelines tied to clinical outcomes and DoD priorities.

  • Computationally efficient digital twins usable on edge devices for prolonged field care and medics in forward areas.

  • Interoperable model-into-workflow tools connecting simulations with electronic health records, telemedicine, and battlefield decision aids.

Current and Emerging Technologies in Biophysics and Biomedical Modeling

Multiscale computational physiology

Couples cellular signaling, tissue mechanics, and organ-level hemodynamics to predict responses to trauma, resuscitation, and therapeutics. Enables virtual trials and sensitivity analyses for combat-relevant injuries.

Finite element and biomechanics modeling

High-fidelity simulations of blast, ballistic, and blunt-force trauma to inform protective equipment, surgical planning, and reconstructed anatomy for regenerative strategies.

Digital twins and patient-specific modeling

Personalized virtual patients drive scenario-based planning, anticipate clinical deterioration, and tailor interventions for prolonged casualty care or constrained evacuation timelines.

Machine learning–augmented mechanistic models

Hybrid approaches fuse physics-based models with data-driven methods to improve prediction from sparse battlefield sensors and to flag atypical trajectories such as occult hemorrhage or infection.

Rapid in silico trial platforms

Scalable simulation environments accelerate evaluation of devices, blood products, and therapeutics, reducing time to iterate prototypes relevant to DoD operational requirements.

Edge-capable real-time decision support

Lightweight algorithms and compressed models engineered for wearables, portable monitors, and handheld devices that provide medics with actionable predictions under connectivity constraints.

Importance to Military Medicine

Optimizes combat casualty care

Predictive models guide hemorrhage control, resuscitation strategies, and triage decisions where rapid clinical judgment can change survival.

Supports prolonged and austere care

Digital twins and edge models extend expertise into far‑forward environments, enabling medics to manage delayed evacuation and prolonged field care.

Improves readiness and medical planning

Simulations inform training, force health protection, and logistics for blood, antibiotics, and surgical capabilities under combat conditions.

Accelerates technology maturation

In silico evaluation shortens development cycles for devices and therapeutics prioritized by DoD, reducing time to deployment and civilian benefit.

Alignment with the MTEC Mission

Directly supports MTEC’s mission by accelerating transition of military-relevant medical technologies through validated modeling, simulation, and rapid iteration.

Aligns with DoD priorities—combat casualty care, force health protection, and prolonged care—by providing evidence-based decision tools and virtual testbeds.

Enables multidisciplinary consortia work across academia, industry, and military clinicians to validate models against operationally relevant datasets.

Supports dual-use outcomes by accelerating civilian translation of validated simulation tools for trauma care, infectious disease response, and surgical planning.

Dual-Use (Military + Civilian) Applications

Use cases include virtual testing of hemorrhage control devices, predicting sepsis trajectories for field triage, digital-twin surgical rehearsal, and optimized sensor networks for remote monitoring.

Explore MTEC Members with Biophysics and Biomedical Modeling Capabilities

MTEC members bring combined strengths in computational modeling, biomechanics, clinical trial design, regulatory strategy, and field validation. Industry accelerates engineering; academic partners provide model rigor and validation; military clinicians ensure operational relevance. Explore member profiles to identify collaborators with expertise in digital twins, in silico trials, edge analytics, and translational validation to advance military medical capability.

156 Members with Biophysics and Biomedical Modeling capabilities.

Member
SIMETRI

SIMETRI is a woman-and-minority owned small business based in Winter Park, Florida, specializing in modeling, simulation, and training technologies. Founded in 2009, the company focuses on delivering innovative products and services that enhance the human experience and improve client outcomes through advanced training and program management analysis.

Member
Humanetics Corporation

Humanetics Corporation is a clinical-stage pharmaceutical company based in Minneapolis, Minnesota, focused on developing and commercializing products to enhance human health and wellbeing. Founded in 1988, the company specializes in radiation modulators, adjunctive oncology therapies, and pulmonary protective therapies, particularly for COVID-19. Humanetics is known for its lead drug candidate, BIO 300, which is being developed as a radioprotectant for military and civilian use, as well as a treatment to improve outcomes in cancer patients receiving radiotherapy. The company is actively engaged in research programs for non-small cell lung cancer, prostate cancer, and head and neck cancers.

Member
Teleflex

Teleflex is a global provider of medical technologies designed to improve the health and quality of people's lives. The company focuses on purpose-driven innovation to empower healthcare professionals and enhance patient outcomes across various medical fields.

Member
Aware Custom Biometric Wearables

Aware Custom Biometric Wearables, is a leading innovator in cutting-edge in-ear technology, specializing in superior custom hearing protection solutions and biometric hearables. Our groundbreaking in-ear solutions feature enhanced hearing capabilities, continuous monitoring, and the collection of medical-grade biometric data, all designed to enhance human performance and safeguard lives. Our commitment to innovation is reflected in our meticulously crafted in-ear devices. Thanks to our patented 3D Ear Scanner technology, we provide a custom fit tailored to the unique shape of each individual's ear which optimizes the performance of sensors. Aware is transforming the ear into a dynamic platform for health and human performance by collecting medical-grade data, delivering actionable AI-driven insights, and enabling precision therapeutics within devices we wear in our everyday lives. Our technology serves a diverse range of sectors within healthcare, military, and industrial. Proudly U.S.-based, offices in Atlanta, GA and San Diego, CA. www.AwareCBW.com.

Member
Seek Labs

Seek Labs is a biotechnology company headquartered in Salt Lake City, Utah, dedicated to advancing scientific discovery and delivering universal healthcare solutions. The company specializes in next-generation point-of-care molecular diagnostics and programmable CRISPR-based therapeutics, aiming to bridge the gap between disease outbreak and intervention. Powered by its proprietary AI discovery engine, BioSeeker™, Seek Labs is building a modular, full-stack system that enables rapid response to emerging pathogens, scalable precision treatments, and accessible diagnostics. The company is committed to global health innovation, sustainability, and community engagement, and is a proud member of Utah's BioHive life sciences ecosystem. Seek Labs' mission is to empower individuals with healthcare solutions tailored to their specific needs, revolutionizing the detection and treatment of diseases for both human and animal health.

Member
BioPharma Connections

BioPharma Connections is an independent, woman-owned consulting firm founded in San Francisco in 2007, providing strategic business development, technical operations, regulatory, product development, and commercialization support to the life sciences industry. Serving pharmaceutical, biotechnology, medical device, and diagnostic companies globally, the firm specializes in facilitating connections between organizations, service providers, CROs, CDMOs, and investors—guiding clients from concept to commercialization, with deep expertise in regulatory compliance, emerging technologies, and diverse therapeutic areas.

Member
Sonogen Medical Inc.

Sonogen Medical Inc. is dedicated to researching, developing, and commercializing next-generation ultrasonic bone fracture healing technology. The company combines expertise in fluid mechanics, biophysics, sonar, and medical ultrasound to create safe and effective devices for bone healing.

Member
The University of Texas Medical Branch at Galveston

UTMB is dedicated to supporting research, education, and scholarly endeavors, with a focus on creating the future of healthcare through innovative research and community engagement.

Member
Noblis

Noblis is a nonprofit research and technical organization supporting federal missions in defense, health, environment, and security. Emphasizing applied sciences, engineering, digital transformation, artificial intelligence, cloud, and cybersecurity, Noblis provides objective solutions for government agencies confronting complex operational and scientific challenges.

Member
Vindhya Data Science

Vindhya Data Science is a women-owned small business headquartered in North Carolina, USA, with a presence in RTP and Boston. We specialize in bioinformatics, genomics, artificial intelligence, and data engineering, cheminformatics, evidence-based medicine, epidemiology and related disciplines. Vindhya partners with federal government agencies, leading academic medical centers, and pharma/biotech organizations to transform large datasets into informed decisions using advanced data science technologies. With over 100 years of combined experience, 150+ publications, and 73+ successful projects, Vindhya is committed to delivering impactful solutions in the life sciences sector.

Member
The University of Chicago

The University of Chicago is a prestigious urban research university committed to rigorous inquiry and intellectual freedom. Founded in 1890, it has produced numerous Nobel laureates and is known for its transformative education and groundbreaking research across various fields. The university fosters an inclusive and diverse learning environment, encouraging participation from all community members.

Member
JDSAT, Inc.

JDSAT is a decision science company that fuses human insight with algorithmic precision to help organizations make faster, better-informed decisions, when the stakes are high, and the margin for error is low. We work across defense, interagency, and health sectors to build decision ecosystems that thrive in uncertainty. Whether you're leading transformation inside government or solving tough problems as a prime, JDSAT is your edge in complexity.

Member
Booz Allen Hamilton

Booz Allen Hamilton is a leading management and technology consulting firm with over 110 years of experience. The company is dedicated to empowering people to change the world through innovative solutions in various sectors including cybersecurity, artificial intelligence, engineering, and defense. Booz Allen partners with government and commercial clients to tackle their most complex challenges, leveraging a culture of innovation and a commitment to excellence. The firm operates with core values of integrity, courage, service, ingenuity, and a commitment to diversity and inclusion.

Member
PinMed, Inc.

PinMed, Inc., is a National Innovation Award-winning bioinformatics/medical-device company that develops high-fidelity cardiovascular monitoring systems, personalized (adaptive) software, and integrated systems and custom solutions for tracking cardiovascular data in the most challenging environments (e.g., intensive activity, extreme electromagnetic interference, and interventional cardiovascular procedures) and identifying subtle but clinically important indicators of cardiovascular events. PinMed’s award-winning solutions include versatile, multisensor, high-fidelity monitoring systems for various hospital and ambulatory settings. The company has extensive experience in electronic and mechanical engineering, development of software and firmware for various processors, computational modeling, and cardiovascular physiology. PinMed’s flagship mobile platform, PELEX, provides unparalleled versatility in physiological monitoring and has been cleared by the FDA for diagnostic 12-lead ECG testing and various types of ambulatory monitoring.

Member
DLH Holdings Corp.

DLH delivers improved health and national security readiness solutions for federal programs through science research and development, systems engineering and integration, and digital transformation. With over 3,200 employees, DLH is committed to solving complex problems faced by civilian and military customers, leveraging advanced technologies and methodologies to enhance health outcomes and operational readiness.

Member
Alzheimer’s Treatment Centers of America

This organization specializes in integrated, science-based treatment and diagnostics for Alzheimer’s, dementia, and cognitive decline. Utilizing a precision medicine approach, the center combines advanced AI analysis, biomarker-driven planning, and multimodal therapies including brain imaging, neurocognitive testing, and over 50 clinical and supportive treatment modalities. The care model addresses both the root causes and neuropsychiatric aspects of cognitive impairment, delivered by a multidisciplinary team with expertise in functional, regenerative, and collaborative behavioral medicine.

Member
Texas Christian University

Texas Christian University (TCU) is a private institution in Fort Worth, Texas, offering undergraduate, graduate, and doctoral programs across diverse disciplines. The university emphasizes interdisciplinary research, experiential learning, faculty-student collaboration, and engagement with both local and global communities. Core values include academic excellence, innovation in research and creative activities, inclusive culture, and leadership development.

Member
Tietronix Software, Inc.

Tietronix Software, Inc. is a minority-owned small business founded in 1999, located in Houston, Texas, near NASA Johnson Space Center. The company specializes in providing innovative software solutions and services across various sectors including medical, aerospace, and renewable energy. Tietronix is committed to high quality, reliability, and customer satisfaction, leveraging a diverse workforce and a strong project management team to deliver complex, mission-critical systems.

Member
Nanochon

Nanochon develops 3D-printed synthetic orthopedic implants for articular cartilage repair, focusing on minimally invasive treatments for patients ineligible for joint replacement. The company utilizes advanced biomaterials and additive manufacturing to deliver implants that provide immediate mechanical support while promoting biological integration and cartilage regeneration. Nanochon supports its technology with preclinical animal studies, in vitro validation, and regulatory-driven clinical trials across North America.

Member
Altec

Altec is dedicated to advancing human potential by developing innovative human sensing technologies that enhance health science, operational security, and human performance. Founded in 1997 by Carlo De Luca, the company focuses on translating cutting-edge concepts into practical solutions that shape our understanding of human physiology. Altec's mission is to reimagine human potential through discovery, innovation, and collaboration, making significant strides in healthcare, security, and performance enhancement.

Member
Exponent

Exponent is a multidisciplinary science and engineering consulting firm serving sectors including healthcare, energy, manufacturing, and consumer products. From medical devices, pharmaceuticals, and supplements to digital health and wearables, we deliver rigorous science that quantifies impacts on human health. Exponent helps you push the envelope on the development, deployment, safety, and effectiveness of cutting-edge drugs, devices, and diagnostics — concomitantly balancing benefits and risks. Count on our multidisciplinary, data-driven, evidence-based assessments to give you clarity on your most complex product needs and challenges. With lives on the line, innovations that support healthcare demand the highest levels of scientific rigor. Whether you’re developing a novel drug, a sturdier stent, or a faster flu test, you need clear answers to complex questions, quickly. Exponent supports our life sciences clients across the total product lifecycle by solving critical design, regulatory, safety, and market access challenges. We can collaborate with you throughout your journey, helping you navigate risks and opportunities — and optimize outcomes — with science-based strategies and specialized expertise.

Member
Stream Biomedical

Stream Biomedical is a clinical-stage biotechnology company developing first-in-class biologic therapies to restore neurological function by activating the brain’s natural repair mechanisms. Founded in 2016, the company is advancing a protein therapeutic focusing on treating brain injuries and neurodegenerative diseases—including stroke, traumatic brain injury, and Alzheimer’s disease—by supporting neurovascular repair and modulating inflammation. Stream Biomedical’s approach is underpinned by rigorous preclinical and translational research, with the goal of changing outcomes for patients affected by severe neurological conditions.

Member
University of Cincinnati Office of Research

The University of Cincinnati Office of Research is a premier R1 urban research institution dedicated to advancing transformative knowledge and disruptive discoveries that address real-world challenges. Guided by its Research2030 strategic plan, the Office fosters interdisciplinary collaboration, supports innovative research initiatives, and connects industry, government, and community partners with UC's thought leaders. The Office accelerates economic growth and societal impact by investing in key research strengths such as analytics, cyber, robotics, sensors, skin science, adolescence, cancer, digital humanities, infectious diseases, medical devices, neuroscience, smart cities, sustainability, urban futures, and water. With a strong commitment to transparency, compliance, and research security, the Office provides comprehensive support for faculty, students, and staff throughout the research lifecycle, ensuring excellence and integrity in all scholarly activities. Specialized programs and support offices include biosafety, animal care, research integrity, cybersecurity, human research protection, defense research initiatives, government cost compliance, and radiation safety, all designed to uphold the highest standards of ethical, safe, and innovative research. The Office also keeps the community informed and engaged through its monthly 'Findings' newsletter, highlighting impactful research, partnerships, and opportunities.

Member
PPD

PPD, a clinical research business of Thermo Fisher Scientific, is a leading provider of global contract research organization (CRO) solutions. The company is dedicated to helping clients accelerate the development of life-changing therapies through comprehensive drug development, laboratory, and lifecycle services. With a commitment to operational excellence and innovative technology, PPD empowers its customers to bring therapies to market faster and improve patient health. PPD has been recognized as an industry leader in clinical development digital transformation services and patient engagement digital transformation. With over 30 years of clinical leadership and a workforce of more than 30,000 employees globally, PPD has conducted over 2,100 trials in the past five years.

Member
Simbex

Simbex is a leading partner in medical device and consumer health product design and development, recognized for transforming complex ideas into commercially successful solutions. With a multidisciplinary team, Simbex excels in engineering, product design, software, data analytics, and commercialization strategy, supporting innovators from concept to market. Their mission is to deliver impactful medical devices and consumer health products that improve health outcomes and quality of life. Simbex is known for its holistic approach, deep regulatory expertise, and commitment to innovation and excellence in the health technology sector. The company is also active in thought leadership, regularly publishing regulatory and reimbursement updates, and hosting educational webinars for the MedTech community. Simbex maintains a robust Quality Management System compliant with ISO 13485 and FDA 21 CFR 820, ensuring high standards in product development. The company is also committed to supporting diversity in MedTech, including initiatives for women in the sector. Simbex's leadership and advisory team bring decades of experience in biomedical engineering, commercialization, regulatory affairs, and technology innovation, further strengthening its position as a trusted partner in the MedTech ecosystem.

Member
Nanovaccine Institute

The Nanovaccine Institute, established at Iowa State University in 2017, is a national transdisciplinary research consortium focused on advancing nano-based technologies to treat and prevent diseases. The institute aims to revolutionize public health outcomes through the design and promotion of nano-based vaccines and therapeutics.

Member
TRI Medical, Inc.

TRI Medical, Inc. develops and supplies educational simulation models and training services to enhance the diagnostic and manual skills of healthcare professional students and new graduates. The company focuses on providing real-time, psychomotor feedback tools for medical education programs and healthcare organizations, aiming to improve confidence, self-efficacy, and diagnostic accuracy prior to clinical practice.

Member
UVM An-Cockrell Lab Center for Biomedical Digital Twins

The UVM An-Cockrell Lab Center for Biomedical Digital Twins is a multidisciplinary research group leveraging advanced computational methods, including machine learning, agent-based modeling, and high-performance computing, to study complex biomedical and physiological phenomena. Their mission is to bridge the gap between basic science and clinical interventions by developing digital twins and computational models that inform precision medicine, therapeutic discovery, and translational research. The lab's work spans detailed organ and disease modeling, AI-driven clinical applications, and collaborative projects such as DARPA-funded initiatives, aiming to revolutionize healthcare through technology and simulation.

Member
Profusa, Inc.

Profusa, Inc. is a pioneering digital health company based in the San Francisco Bay Area, dedicated to making the body’s chemistry easily accessible to improve health and wellness. Profusa develops tissue-integrating biosensors for continuous, real-time monitoring of body chemistries, empowering individuals and clinicians with actionable, medical-grade data to transform personal health management and disease prevention. Their unique bioengineering approach overcomes the foreign body response, enabling long-term, in-body monitoring through tiny, flexible biosensors that become one with the body. Profusa’s technology platform supports both consumer and medical applications, with a vision to revolutionize personalized medicine and digital health. The company is supported by significant grant funding from agencies such as DARPA and NIH, and collaborates with leading academic, hospital, and industry partners worldwide.

Member
Solventum

Solventum is a healthcare company dedicated to enabling better, smarter, and safer healthcare solutions. With a legacy of innovation, Solventum focuses on improving patient outcomes through advanced medical technologies, oral care solutions, health information technology, and purification and filtration systems.

Member
Accenture

Accenture is a global professional services company with extensive capabilities in strategy and consulting, digital transformation, technology, and operations. The company aims to drive innovation and efficiency across various industries, helping clients navigate complex challenges and seize opportunities in a rapidly changing environment. Accenture is committed to creating positive change around the world and ensuring responsible business leadership for its people, clients, and communities. The company emphasizes continuous learning, responsible AI practices, and a culture of belonging and diversity.

Member
The University of Texas at Arlington Research Institute

The UT Arlington Research Institute (UTARI) specializes in applying cutting-edge technologies to real-world engineering problems. Our collaborative endeavors reflect a commitment to excellence, integrity, and respect for all, bringing economic growth and fulfillment to our families, business partners, university, and community.

Member
Kromek Group plc

Kromek Group plc develops advanced detection technologies for radiological, nuclear, and biological threats using Cadmium Zinc Telluride (CZT) solid-state detectors. The company offers manufacturing and R&D for high-resolution gamma and neutron detectors, networked and wearable monitoring devices, and automated pathogen detection platforms. Its solutions serve the civil nuclear, medical, environmental, defense, and public health sectors worldwide, enhancing safety, operational efficiency, and health security.

Member
Augmntr

Augmntr is a software and systems engineering company specializing in Augmented Reality and Virtual Reality technologies. We offer solutions for presenting real-time, real-world data to users in a hands-free, eyes-out interface, aiming to transform the way people and complex data sets interact.

Member
Kitware

Kitware is dedicated to delivering innovation through advanced technical computing, state-of-the-art AI, and tailored software solutions. Founded in 1998, the company emphasizes an open-source philosophy, fostering collaboration and transparency to solve complex scientific challenges. Kitware is committed to advancing scientific understanding and improving technology through its extensive expertise in various domains, including AI and deep learning.

Member
MediView XR, Inc.

MediView XR, Inc. is a Cleveland, Ohio-based med-tech company pioneering the use of augmented reality (AR) and mixed reality to transform medical imaging, surgical navigation, and patient care. Their mission is to advance healthcare delivery with intuitive visualization, seamless collaboration, and evidence-based insights. MediView’s vision is to simplify, democratize, and inform healthcare delivery by unlocking the full potential of 3D data for image-guided procedures. Through partnerships with leading organizations such as GE HealthCare, Mayo Clinic, and Microsoft, MediView delivers AR-powered visualization and navigation solutions that provide clinicians with unprecedented 3D "X-ray vision," real-time collaboration, and improved procedural accuracy. The company is recognized for its innovative approach to addressing health equity by expanding access to advanced care, especially in rural and underserved communities. MediView’s technology is also making significant strides in medical education, enabling immersive, hands-on learning and remote collaboration for students and clinicians.

Member
Hyperion Biosystems

Hyperion Biosystems, an MIT spin-out tough tech company, is developing revolutionary diagnostics at the interface of chemistry, computer vision, and algorithms (both physics-based and AI-enhanced) to address medicine’s most expensive blind spot – sepsis. Our flagship molecular platform (Helios™) is able to simultaneously detect hundreds of target species, direct-from-blood, with excellent sensitivity (single-copy) and specificity (VAFs in excess of 0.0001%). These capabilities are tailer-made for rapid, pre-culture, pathogen ID and AMR marker detection in patients with suspected BSI or sepsis.

Member
GrayMatters Health

GrayMatters Health is transforming mental healthcare by providing evidence-based technology that enhances standard-of-care therapies. Their flagship product, Prism for PTSD, is the first FDA-cleared self-neuromodulation device designed to help patients manage PTSD symptoms through innovative brain activity regulation techniques.

Member
CellBios

CellBios is a biotechnology company specializing in the design, development, and manufacturing of single-use bioprocessing and medical device solutions for healthcare, biotechnology, and regenerative medicine sectors. The company operates GMP and ISO-certified cleanroom facilities, offering a comprehensive portfolio of cryopreservation products, bioreactors, fluid management systems, advanced packaging, and specialty devices. By leveraging expertise in extrusion, molding, assembly, sterilization, quality control, and regulatory compliance, CellBios provides customized, scalable solutions to support blood transfusion, cell and gene therapy, biologics manufacturing, and clinical workflows.

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Athari BioSciences

Athari BioSciences is a CLIA-certified BSL-2 diagnostic, research, and training laboratory advancing healthcare through scientific innovation in diagnostics, therapeutics, genomic research, and workforce development. With a mission focused on improving health equity, personalized medicine, and education, the company provides laboratory, research, and regulatory services, and offers hands-on learning experiences to foster the next generation of life sciences professionals.

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Alira Health

Alira Health is a global consulting and clinical services company that aims to humanize healthcare and life sciences through innovative technologies and expert guidance. They focus on improving patient outcomes by integrating patient voices into the development of treatments and enhancing care quality across the healthcare ecosystem.

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University City Science Center

The University City Science Center (the Science Center) is a 501(c)3 non-profit organization based in Philadelphia, PA. The Science Center catalyzes innovation to maintain the technological superiority of the American military and the strength of the American economy. The Science Center’s core activities include programming to support and train entrepreneurs, commercialize dual use technologies, expand available capital for high growth firms, and cultivate the domestic STEM talent pipeline. We empower early-stage companies to secure and manage federal funding through specialized assistance. By leveraging our government relationships, providing comprehensive proposal development, and deploying sophisticated award management, the Science Center streamlines the process for startups in accessing federal funding. By ensuring that American scientific and technological innovations are rapidly advanced and integrated into defense and dual-use applications, the Science Center strengthens the US industrial base, enhances military readiness, and safeguards national security interests. This lab-to-market pipeline is critical to maintaining technological overmatch, securing supply chain resilience, and reinforcing biosecurity infrastructure. The Science Center’s innovation acceleration initiatives can directly contribute to the Department of Defense’s modernization priorities by reducing reliance on foreign technologies, fostering high-growth industries in critical technology areas, and ensuring that STEM advancements serve as strategic assets to protect and advance US interests. Since its founding, the Science Center’s commercialization and small business programming efforts have supported more than 700 companies, leading to 29,100 jobs with an average salary of $105,000 and $7.6 billion in annual economic impact in Greater Philadelphia. Through its commercialization programs, the Science Center has supported a range of mission-critical innovations that align with DoD priorities, including warfighter readiness, medical technology advancement, and operational resilience.

Member
Benchmark Biotech

Benchmark Biotech is a leading contract research organization focused on advancing medical device research and healthcare. Specializing in biotechnology and pharmaceutical development, the company supports the creation of innovative medical devices for trauma and combat casualty care. With a team of experienced scientists, specialists, and physicians, Benchmark Biotech is committed to improving patient outcomes through high-quality research and collaborative partnerships.

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University of Kentucky

The Office of Sponsored Projects Administration (OSPA) at the University of Kentucky is dedicated to transforming tomorrow by streamlining grants and contracts. OSPA provides essential services to faculty and staff, including assistance with proposal preparation, award negotiation, and compliance with sponsor policies.

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Prevent Biometrics

Prevent Biometrics develops validated wearable systems that use embedded sensors to monitor and analyze head impacts in real time. The company's mouthguard-based platforms provide objective data and analytics for sports and military applications, supporting player safety, research, and injury detection. Collaborating with academic and military institutions, Prevent Biometrics aims to advance the understanding and prevention of head injuries.

Member
Parallel Bio

Parallel Bio offers end-to-end drug discovery services powered by scalable human immune organoids and a large diverse biobank. These include comprehensive drug discovery pipelines that progress from disease target identification to IND filing, human tissue-based preclinical testing and validation of therapeutics (as a "clinical trial in a dish" alternative to animal models), and personalized medicine analytics for patient stratification and precision insights. Parallel Bio also provides collaborative services for pharma partners, high-throughput compound testing on diverse human models, data generation and analytics from immune organoid systems, and support for AI-driven biological modeling to accelerate the right candidates toward the clinic.

Member
Southwest Research Institute (SwRI)

Southwest Research Institute (SwRI) is a nonprofit research and development organization that provides independent, premier services to government and industry clients. Founded in 1947, SwRI is committed to advancing science and technology to benefit humanity, focusing on innovative solutions that improve human health and safety. With a diverse range of technical divisions, SwRI addresses complex challenges in various fields including mechanical engineering, materials, aerospace, automotive, biomedical, and more.

Member
HNu Photonics

HNu Photonics is a Hawai’i-based science and technology company specializing in the research, design, fabrication, and assembly of advanced photonics, optics, and instrumentation technologies. The company provides integrated solutions across biotech, defense, energy, and advanced manufacturing sectors, offering vertically-integrated services from concept development to finished products. Areas of focus include renewable energy systems, defense photonics, specialized optics, and medical imaging technologies.

Member
Torpedo Therapeutics

Torpedo Therapeutics is dedicated to advancing the field of neurological disorder treatment through high-precision, closed-loop deep brain stimulation (DBS) therapy. Their mission is to enhance the efficacy and safety of DBS by innovating electrode technologies and developing automated data analysis platforms. This approach aims to minimize side effects and improve long-term outcomes for patients with conditions such as Parkinson’s disease, Essential Tremor, Dystonia, and drug-resistant Epilepsy.

Member
ALA Scientific Instruments, Inc.

ALA Scientific Instruments, Inc. is dedicated to advancing life science through innovative instrumentation. With over thirty years of experience, the company provides researchers with the tools necessary for challenging experiments in biophysics and cellular electrophysiology.

Member
JURA Bio

JURA Bio is pioneering AI-native drug discovery by bridging the gap between computational design and physical reality in biological AI. Their mission is to revolutionize the discovery and development of safe and effective drugs, making even the hardest therapeutic targets tractable. By leveraging manufacturing-aware generative models, JURA Bio not only designs new therapeutics but also builds, tests, and learns from them at unprecedented scale. Their approach integrates machine learning, synthetic biology, and high-throughput experimentation to create a new paradigm in drug discovery, where AI learns from tens of billions of real protein interactions and every candidate is inherently human-safe.

Member
NTx Bio

NTx Bio (Nature’s Toolbox, Inc.) is revolutionizing biomanufacturing by enabling on-demand, decentralized, and scalable production of high-quality RNA and proteins. Our mission is to democratize access to medicines by overcoming the bottlenecks of traditional, centralized manufacturing. Through proprietary, synthetic biology platforms like NTxscribe® (mRNA production) and NTxpress® (cell free protein production), NTx empowers researchers and companies to accelerate the development and delivery of personalized and mass-scale therapeutics, making next-generation medicine more accessible, sustainable, and efficient, while eliminating supply chain concerns by using 100% domestic inputs and production capabilities.

Member
University of Louisville Office of Research and Innovation

The University of Louisville Office of Research and Innovation is a premier metropolitan research institution dedicated to advancing knowledge, fostering creativity, and driving innovation across diverse disciplines. Its mission is to support research, scholarship, and creative activity, translating UofL discoveries to benefit Louisville, Kentucky, the nation, and the world. Recognized as a top-tier 'Research 1' university, UofL supports a vibrant ecosystem of research centers, institutes, and collaborative initiatives spanning medicine, engineering, business, and the arts. The office provides robust support for postdoctoral fellows, industry partnerships, entrepreneurship, and access to state-of-the-art core facilities and research tools, making it a hub for innovation, technology transfer, and startup development. UofL is committed to the highest standards of research integrity, compliance, and ethical conduct, ensuring responsible and impactful research outcomes. The office offers comprehensive resources for research participants, including specialized support for children in research, and maintains a strong focus on research policies, technology licensing, industry collaboration, and researcher development through training and funding opportunities. UofL's vision is to support ideas that change, improve, and even save lives, continuously raising the bar for research excellence and societal impact. The office is structured to provide specialized support through dedicated units, research deans, and operational teams, ensuring efficient management and advancement of the university's research enterprise. UofL also maintains transparent and federally compliant practices for indirect cost recovery, ensuring full cost recovery for sponsored projects and providing clear guidance on budget and financials for researchers and partners.

Member
Radical Numerics

Radical Numerics is an AI research laboratory developing general biological intelligence through large-scale, multimodal AI models tailored for biological data. The organization advances architectures, numerical methods, and hardware-efficient systems for scientific AI, enabling progress in therapeutic discovery, genome analysis, biodefense, and scalable biological intelligence.

Member
Persist AI

Persist AI is a biotechnology company pioneering the use of AI-driven robotics to accelerate and transform pharmaceutical formulation development. Their mission is to deliver life-saving drugs faster, with fewer side effects, and improved patient outcomes by leveraging advanced automation, machine learning, and high-throughput experimentation. Persist AI's integrated platform addresses the bottlenecks of traditional drug formulation by combining custom robotics, computational chemistry, and proprietary AI models, enabling rapid, scalable, and cost-effective development of complex drug delivery systems such as long-acting injectables. With a global presence and a team of experts in drug delivery, automation, and machine learning, Persist AI is committed to making advanced drug delivery systems more accessible and efficient for the pharmaceutical industry worldwide. The company also demonstrates a strong commitment to data protection, privacy, and security, implementing robust technical and organizational measures in compliance with international standards.

Member
University of Wisconsin–Madison

The University of Wisconsin–Madison is a leading public research university dedicated to academic excellence, multidisciplinary research, and community outreach. Founded in 1848, it advances knowledge across humanities, sciences, engineering, and healthcare, and is recognized for innovation in higher education, significant research activity, and global impact. The institution is guided by the Wisconsin Idea, striving to improve lives on and beyond campus.

Member
Pennington Biomedical Research Center

Pennington Biomedical Research Center, a campus of the LSU System, is a global leader in medical discovery and translational science. Pennington Biomedical is dedicated to understanding the biological triggers of disease and nutrition-related conditions. Through basic, clinical, and population research, Pennington Biomedical pursues a bold vision: to lead the world in promoting nutrition and metabolic health and eliminating metabolic disease through scientific discoveries that deliver solutions from cells to society. Building on this foundation, Pennington Biomedical has become a trusted partner in human performance science, with over 30 years of collaboration with the Department of War and a legacy of more than 170 military-focused research projects. This expertise now extends to spaceflight, where Pennington Biomedical seeks to address the physiological demands of long-duration missions. At the forefront of these efforts is the Center for Human Performance Optimization, which unifies military and spaceflight performance science to drive cross-domain innovation. The Center conducts multidisciplinary research to understand and enhance human capabilities under extreme stress. Research spans clinical trials, operational studies, and advanced analytics, with integrated approaches across nutrition, exercise, sleep, pharmaceuticals, cognitive health, and emerging technologies. Studies focus on preventing performance decline and pushing the boundaries of human potential in the harshest environments. Pennington Biomedical’s world-class infrastructure supports this mission. The Clinical Trials Unit includes a 90,000-square-foot outpatient clinic, a 20-bed inpatient unit with metabolic chambers and sleep labs, a metabolic kitchen, dedicated exercise facilities, and flexible-use research space. These resources enable rigorous, multidisciplinary trials. The CTU is further supported by advanced imaging, biochemistry, and data management cores, as well as animal research platforms focused on metabolism, behavior, and comparative biology. Through its integrated platforms and mission-driven focus, Pennington Biomedical is shaping the future of human performance science. The Center for Human Performance Optimization delivers real-world impact for national defense, space exploration, and elite human capability—ensuring warfighter readiness, astronaut resilience, and human excellence across the most challenging environments.

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Israel Innovation Authority

The Israel Innovation Authority is the central governmental body responsible for fostering and advancing Israel's innovation ecosystem. Its mission is to power innovation through investment, insight, and impactful programs, supporting high-tech entrepreneurship, deep-tech ventures, and global collaborations. The Authority provides non-dilutive funding, strategic support, and regulatory guidance to startups and established companies, ensuring Israel remains a global leader in technology and innovation. With a focus on sectors such as AI, bioconvergence, foodtech, climate tech, and more, the Authority bridges academia, industry, and international partners to address humanity's pressing challenges and drive economic growth. Israel's tech ecosystem, often called the "Startup Nation," is characterized by a culture of bold experimentation, interdisciplinary collaboration, and resilience, making it a global powerhouse for innovation. The Authority also plays a pivotal role in shaping national innovation policy, supporting R&D, and facilitating co-investment opportunities for international investors. The Authority's unique features include proactive future-readiness, risk-absorbing investment models, global market integration, and resilience in times of crisis, such as the deployment of Fast-Track bridging funds to protect startups. The Authority also operates innovation centers and manufacturing accelerators to expand high-tech opportunities geographically and demographically, and regularly identifies and supports emerging technologies with high potential impact. The Authority supports a vast portfolio of startups and scale-ups across diverse sectors, including medical engineering, software, electronics, foodtech, biotech, and more, through programs such as Tnufa, Technological Incubators, R&D grants, and international collaborations.

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SRI International

SRI International is an independent nonprofit research institute with a rich history of supporting government and industry. For almost 80 years, SRI has collaborated across technical and scientific disciplines to discover and develop groundbreaking products and technologies, delivering world-changing solutions for a safer, healthier, and more sustainable future. The Nomura-SRI Innovation Center (NSIC) further enhances SRI's mission by bridging the gap between Japan and Silicon Valley, fostering corporate innovation and talent development.

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Spectral AI

Spectral AI develops artificial intelligence-driven diagnostic solutions for wound management, with a focus on burns and diabetic foot ulcers. Utilizing multispectral imaging and advanced machine learning algorithms, the company provides objective, real-time predictions of wound healing potential to support clinical decision-making. Their technology improves accuracy in wound assessment, helping clinicians address diagnostic gaps and reducing subjectivity in care. Spectral AI’s solutions support both risk stratification and treatment planning, aiming to optimize outcomes and reduce healing-related complications.

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George Mason University

The Institute for Biohealth Innovation (IBI) at George Mason University unites over 300 faculty and thousands of students across 34 departments to advance human health and well-being through innovative research. The IBI focuses on major health challenges, including infectious diseases, cancer, brain and behavior, and cardiovascular health, collaborating with national and international partners to implement solutions that enhance health outcomes.

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StethX

StethX is a Georgia Tech spin-off developing Dual-Use technologies, Alt-PNT and AI powered wearables. The company is dedicated to advancing cardiovascular and pulmonary healthcare through innovative, wearable medical devices that capture the acoustic fingerprints of the heart and lungs. By leveraging precision wearable technology, machine learning, and artificial intelligence, StethX aims to provide real-time, customized data for patients and clinicians, enabling informed treatments and improved outcomes. Their mission is to make healthcare more accessible, efficient, and personalized, ensuring everyone has access to high-quality, patient-centered care.

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The University of Texas at Austin

The University of Texas at Austin is a leading public research university offering diverse undergraduate, graduate, and professional programs. Committed to open inquiry, academic freedom, and research excellence, UT Austin advances discovery through interdisciplinary collaboration and strong partnerships with government and industry, with impact across health, engineering, energy, artificial intelligence, entrepreneurship, and national security.

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Charles River Analytics

Charles River Analytics is dedicated to developing human-centered intelligent systems that enhance military performance, ensure homeland security, and transform healthcare through advanced technology. With a strong focus on AI, robotics, and human-centered computing, the company aims to solve complex challenges faced by government and commercial sectors. The company also emphasizes its commitment to corporate social responsibility, employee ownership, and innovative training solutions.

Member
University of Minnesota

The University of Minnesota's Research and Innovation Office (RIO) serves as a central resource for conducting, managing, and sponsoring research. It aims to facilitate collaborative research that addresses complex problems and promotes innovations that improve lives. RIO oversees research compliance and administration, fostering a culture of integrity and ethical practices in research. Additionally, RIO is committed to enhancing research capacity through various funding opportunities and strategic initiatives, including the management of specialized facilities for biocontainment research.

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Wyss Institute for Biologically Inspired Engineering at Harvard University

The Wyss Institute for Biologically Inspired Engineering uses biological design principles to develop new engineering innovations that will transform medicine and create a more sustainable world. At the Wyss Institute, we leverage recent insights into how Nature builds, controls and manufactures to develop new engineering innovations - a new field of research we call Biologically Inspired Engineering. By emulating biological principles of self assembly, organization and regulation, we are developing disruptive technology solutions for healthcare, energy, architecture, robotics, and manufacturing, which are translated into commercial products and therapies through formation of new startups and corporate alliances.

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Exo Insights

Exo Insights offers data-driven solutions for training optimization in high-risk and high-stakes environments. The company's system employs biosensors, motion tracking, and analytics to automate instructor tasks, standardize assessments, and deliver real-time objective feedback during training. Their platform focuses on improving performance, enhancing safety, and increasing operational efficiency for training at scale.

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Digital Ether Computing LLC

Digital Ether Computing LLC develops adaptive intelligence systems at the intersection of artificial intelligence, drug discovery, and computational biology. Their mission is to accelerate therapeutic innovation and redefine complex system management through advanced AI architectures, including drug design, industrial automation, defense systems, and neuromorphic computing. The company applies foundational research in adaptive AI to real-world applications where reliability, explainability, and continuous self-improvement are critical.

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Case Western Reserve University

Case Western Reserve University is dedicated to solving the biggest issues of today and tomorrow through innovative research and education. With a commitment to experiential learning, the university offers a wide range of programs and opportunities for students to engage in research, internships, and community service, all within a vibrant campus located in Cleveland, Ohio.

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Henry M. Rowan College of Engineering at Rowan University

The Henry M. Rowan College of Engineering at Rowan University is a leader in engineering education, research, and innovation. With a mission to advance fundamental and applied science and engineering technology, the college emphasizes responsible use of both renewable and fossil resources to enhance material performance and global sustainability. The college fosters a diverse, collaborative environment that educates and trains the next generation of scientists and engineers, while engaging in impactful research, industry partnerships, and community outreach.

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University of Missouri

The University of Missouri is dedicated to advancing research, innovation, and impact through a comprehensive support system for faculty, students, and staff. It aims to foster collaboration, enhance economic development, and promote entrepreneurship, while ensuring compliance with research regulations and ethical standards. The university also emphasizes the importance of interdisciplinary partnerships and provides resources to support veteran entrepreneurs through programs like the Entrepreneurship Bootcamp for Veterans.

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Prolific Machines

Prolific Machines is pioneering the use of optogenetics and AI-driven bioprocess optimization to revolutionize biomanufacturing. Their mission is to illuminate biology’s limitless potential for a healthier tomorrow by enabling the production of next-generation therapeutics and broadening patient access to life-altering medicines. Founded in 2020, the company has developed a unique Photomolecular™ platform that uses light to precisely control cellular functions, boosting yields, improving quality, and enabling the manufacture of complex biotherapeutics. With a focus on strategic partnerships, Prolific Machines collaborates with innovators in biopharma and advanced nutrition, offering flexible, scalable solutions and in-house cell line development up to 200-liter pilot scale. The company is recognized for its commitment to safety, innovation, and a collaborative, diverse team culture.

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Blue Goat Cyber

Blue Goat Cyber provides cybersecurity solutions specifically for medical devices and digital health products, supporting all phases from design and regulatory submission through postmarket management. The company's services emphasize compliance with FDA, EU, and international standards such as ISO 14971, IEC 81001-5-1, and Section 524B, offering Secure Product Development Frameworks, comprehensive penetration testing, risk management, threat modeling, SBOM management, coordinated vulnerability disclosure, and postmarket monitoring. Blue Goat Cyber aims to ensure manufacturers are not only submission-ready but also equipped for ongoing regulatory and procurement demands from hospitals and global regulators.

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Leidos

Leidos is a leading systems integrator in science, technology, and engineering, dedicated to solving some of the world's toughest challenges. The company emphasizes a commitment to integrity, diversity, and sustainability while delivering innovative solutions across various sectors including defense, healthcare, and energy.

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RTI International

RTI International is an independent nonprofit research institute dedicated to improving the human condition. With a vision to address the world's most critical problems through science-based solutions, RTI integrates expertise across social and laboratory sciences, engineering, and international development to deliver reliable data, thorough analysis, and innovative methods that inform public policy and practice.

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Kendall Square Sciences

Kendall Square Sciences is dedicated to designing, developing, and commercializing personal metabolic sensors. Their technology is based on a novel metabolic fuel model and low-cost breath sensor, which measures, tracks, and enhances metabolism. The company aims to provide accurate, affordable, and accessible metabolic measurements to optimize metabolic health with real-time personalized insights.

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University of Nebraska Medical Center

The University of Nebraska Medical Center (UNMC) is dedicated to transforming lives through premier educational programs, innovative research, and extraordinary patient care. Founded in 1869, UNMC is a leader in health sciences education and research, serving as a vital resource for Nebraska and beyond.

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University of Georgia

The University of Georgia (UGA) is dedicated to facilitating instruction, scholarly and creative activity, and research collaborations across disciplines. UGA is a leader in research-based products and innovation, significantly impacting the state of Georgia and beyond through its extensive research initiatives and academic programs.

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Phare Bio

Phare Bio is a social venture dedicated to addressing the urgent global threat of antibiotic resistance through innovative AI and deep learning technologies. The company aims to revolutionize antibiotic discovery and development, ensuring that new antibiotics reach those in greatest need.

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MassBiologics

MassBiologics, part of UMass Chan Medical School, is the only nonprofit, FDA-licensed manufacturer of vaccines and biologics in the United States. With over 100 years of experience, it is dedicated to improving public health through the research, development, and production of biologic products, including vaccines and monoclonal antibodies.

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Lovelace Biomedical

Lovelace Biomedical is a not-for-profit preclinical contract research organization specializing in advancing new therapies, assessing drug and toxicant risks, and characterizing disease using comprehensive in vivo and in vitro models. Leveraging a GLP-compliant facility and scientific collaborations, the organization provides expertise in toxicology, gene therapy, respiratory, infectious disease, neuroscience, and cell biology, with a commitment to quality, regulatory compliance, and advanced analytical capabilities.

Member
Ceres Nanosciences, Inc.

Ceres Nanosciences, Inc. is a privately held company based in Northern Virginia, specializing in the development and commercialization of Nanotrap® hydrogel particle technology. Their mission is to deliver innovative products powered by Nanotrap Technology to address life science needs and provide better patient outcomes. Ceres' products enable the capture, concentration, and preservation of low-abundance analytes from diverse biological and environmental samples, supporting applications in diagnostics, research, and public health surveillance. The company is ISO 9001:2015 certified and collaborates with leading research institutions, public health agencies, and industry partners to advance global health security and biosecurity. Ceres has established a national network of Wastewater-based Epidemiology Centers of Excellence and has received significant funding from the NIH RADx initiative and other organizations to expand its impact in underserved communities. Their technology is widely adopted for wastewater-based epidemiology, proteomics, and nucleic acid analysis, with a strong focus on supporting public health monitoring, early detection of infectious diseases, and environmental bio-surveillance.

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Design Interactive

Design Interactive is a digital transformation company founded in 1998, dedicated to enhancing and optimizing performance through innovative technology solutions. With a focus on software research, development, and cutting-edge UI/UX design, the company aims to exceed expectations and empower organizations with advanced digital tools.

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Medical University of South Carolina

The Medical University of South Carolina (MUSC) is South Carolina’s premier biomedical research institution, dedicated to advancing health through innovative research, education, and clinical care. With over $300 million in research funding and a commitment to addressing pressing health challenges, MUSC fosters collaboration among faculty, staff, and community partners to translate scientific discoveries into impactful health solutions. The South Carolina Clinical & Translational Research Institute (SCTR) at MUSC supports innovative research across the translational spectrum, from basic science to population health, including patient-centered and community-engaged research.

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Simpli-Fi Automation, Inc.

Simpli-Fi Automation, Inc. is dedicated to advancing healthcare through connected technologies that enhance the availability and effectiveness of quality care. With a team boasting over 290 years of combined expertise in software engineering, remote patient monitoring, device engineering, infectious disease control, and advanced manufacturing, Simpli-Fi delivers innovative SaaS and IoT solutions. The company partners with leading organizations and leverages patented and patent-pending technologies to develop non-invasive diagnostic and monitoring devices, aiming to transform patient care, improve provider efficiency, and enable early disease detection.

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Lumeto

Lumeto is a leader in healthcare simulation using AI and immersive technologies. Its simulation platform is used for training, skills assessment and workforce development in the healthcare, safety, and defense sectors. Their flagship platform, InvolveXR, leverages AI to deliver scalable, customizable, and competency-mapped simulations accessible from anywhere. Lumeto's mission is to revolutionize healthcare and workforce preparedness by providing realistic, data-driven, and engaging learning experiences that enhance decision-making, communication, and patient safety. The company partners with leading academic institutions, healthcare organizations, and technology providers globally, and is recognized for its evidence-based, adaptable, and inclusive approach to training the next generation of first responders. Lumeto is at the forefront of innovation with AI-driven virtual patients, customizable learning modules, and partnerships that extend into remote and space healthcare training. Recent advancements include the launch of industry-first customizable AI non-patient characters, a fully customizable AI-driven conversational system for healthcare simulation in VR, and scalable self-directed learning capabilities. Lumeto's InvolveXR platform is recognized for its flexibility, fidelity, and scalability, supporting both asynchronous and synchronous training, and is validated by research demonstrating significant improvements in clinical training outcomes.

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Cytonus Therapeutics, Inc.

Cytonus Therapeutics is pioneering the convergence of artificial intelligence and synthetic biology to revolutionize drug development and delivery. The company challenges the high failure rates of traditional and precision medicines by developing next-generation therapeutics that are both highly effective and safe. Their mission is to create pragmatic shifts in how drugs are designed and administered, focusing on precision, safety, and efficacy to improve patient outcomes.

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Digital Infuzion

Digital Infuzion is a CMMI level 3-appraised information technology firm that specializes in innovative computer services, informatics, and enterprise solutions. With a strong focus on healthcare, the company aims to help clients manage, mine, and make sense of data, driving digital transformations across various sectors. The company prides itself on creativity, openness, and growth, fostering a culture that encourages innovative problem-solving and collaboration.

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MATTER

MATTER is a collaborative community of healthcare innovators dedicated to advancing care, accelerating innovation, and improving lives. The organization provides a platform for startups, corporations, and investors to connect and collaborate on healthcare solutions. MATTER supports entrepreneurs with resources, mentorship, and a dynamic community to foster innovation in the healthcare sector. Since its inception in 2015, MATTER has worked with over 1,000 healthcare technology ventures and partners with industry-leading companies, health systems, and universities.

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Caleo Biotechnologies

Caleo Biotechnologies develops advanced human tissue models to enable more predictive and clinically relevant preclinical research, with a focus on fibrotic and inflammatory diseases. Their core platform integrates epithelial, immune, and mesenchymal/stromal compartments into self-organizing, patient-derived 3D tissue models. These models are used to study disease mechanisms, evaluate drug responses, and de-risk therapy development by capturing patient-specific biology and microenvironmental interactions. Caleo also combines these systems with molecular analysis and scalable, AI-driven analytics to support drug discovery and translational research.

Member
GE HealthCare Technology & Innovation Center

The GE HealthCare Technology & Innovation Center (HTIC) traces its roots to America's first industrial research facility, established by General Electric in 1900. Today, HTIC scientists tackle healthcare challenges through federal funding, academic collaboration, and private sector development. HTIC enhances GE HealthCare competitiveness through development of innovative technologies that enable creation of differentiated and disruptive products. HTIC engages in exploratory research in collaboration with clinicians and academia, guided by societal needs and governmental priorities to discover new markets. With operations in Niskayuna, NY, USA and Bangalore, India, HTIC translates federal research investments into clinical applications.

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SynVivo

SynVivo is a pioneering provider of cell-based microfluidic organ-on-chip platforms, delivering biologically realistic microenvironments for real-time study of cellular behavior, drug delivery, and drug discovery. Their proprietary technology bridges microfluidics and bioengineering, enabling advanced research in life sciences, disease modeling, and personalized medicine. SynVivo's chips support microvascular networks that closely mimic in vivo tissue conditions, validated by scientific research to more accurately reflect human biology than conventional culture methods. The platform is especially impactful for personalized cancer therapy, allowing patient-derived cells to be used for drug efficacy testing in a simulated tumor environment. SynVivo also distributes a wide range of high-quality primary cells and cell lines from various species, supporting research in immunology, cardiovascular, and cancer biology.

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SoarTech

SoarTech is an industry leader in the application of innovative, context-informed AI solutions for Department of Defense (DoD) research and development problems. The company focuses on developing intelligent software that reasons like humans, automating complex tasks, simplifying human-machine interactions, and modeling human behaviors. SoarTech emphasizes a human-centered approach to AI, aiming to enhance human capabilities rather than replace them, and is committed to transparency and explainability in AI systems.

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Reliable Systems Engineering, LLC

Reliable Systems Engineering, LLC is a consulting firm specializing in systems engineering for the medical device industry. The company supports clients—particularly startups, contract developers, OEMs, and CMOs—through expertise in system architecture, requirements development, risk management, verification, and cross-functional coordination. Its mission is to bring clarity, structure, and guidance to complex device development, ensuring regulatory compliance and efficient progress through disciplined engineering practices, all rooted in recognized industry standards and decades of experience.

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Vielight Inc.

Vielight Inc. designs, develops, and manufactures home-use photobiomodulation (PBM) devices for brain health, systemic wellness, and clinical research. The company specializes in non-invasive transcranial and intranasal light therapy systems, including solutions for neural and systemic applications. Their technology is ISO 13485:2016 and MDSAP certified, utilized in over 35 clinical trials, and supported by a significant patent portfolio. Functional outcomes studied include cognitive enhancement, neurological conditions, immune support, brain-body connectivity, and mental well-being. Vielight offers products for professional, research, and consumer use worldwide, and collaborates with leading research institutions.

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Vistendo

At Vistendo, we are dedicated to helping athletes stay healthy and perform at their best. We create accessible technology for early health detection, simplifying the process of making health-related decisions for athletes, parents, and coaches.

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Adaptyx Biosciences

Adaptyx Biosciences is developing a wearable platform for continuous monitoring of multiple biomarkers in dermal interstitial fluid from a single device at the point of need. Built on programmable molecular switch technology that can be reprogrammed across hormones, drugs, electrolytes, peptides, and proteins, it is a single platform adaptable to needs spanning Military Operational Medicine, Combat Casualty Care, Military Infectious Diseases, Clinical and Rehabilitative Medicine, and Chemical, Biological, and Radiological Defense. The platform draws on more than 17 years of pioneering research from our team at Stanford. We have prototype sensors ready for R&D today, and have already demonstrated continuous measurement of multiple biomarkers in humans, including multi-day free cortisol monitoring that captures the diurnal rhythm conventional single-timepoint tests cannot see.

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Tria Federal

Tria Federal is a premier provider of digital services and technology solutions for the federal government, with a mission to support the health, safety, and operational excellence of veterans, service members, and civilians. Formed through the integration of several legacy companies and the acquisition of Softrams in 2024, Tria delivers end-to-end solutions that modernize, streamline, and transform government systems. The company is recognized for its values-driven culture, commitment to diversity and inclusion, and impactful community engagement. With nearly 1,000 employees across more than 40 states, Tria leverages deep expertise in IT, advisory services, and digital transformation to power possible for its government partners.

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Creare

Creare is a leading innovator in technology and product development, specializing in engineering research and development services. With over 50 years of experience, Creare combines sophisticated analytical methods with creative engineering to solve complex challenges across various sectors, including biomedical systems, cryogenics, fluid dynamics, and advanced manufacturing. The company is dedicated to delivering innovative solutions that enhance product functionality, reduce costs, and accelerate time-to-market for its clients. Technology commercialization has been a key part of Creare’s mission since its founding in 1961, leading to significant revenue generation through licensing and spin-offs.

Member
Vira Regen Inc.

Vira Regen is pioneering electrogenetics—a new class of bioelectronic medicine that uses precision electrical signals to modulate gene expression and activate the body’s natural regenerative pathways. Our platform is designed to move beyond conventional electrical stimulation by targeting specific genetic and biological pathways involved in tissue repair and regeneration. By combining bioelectric stimulation with computational biology, transcriptomic profiling, and signal discovery, Vira Regen is developing noninvasive therapies that can precisely influence cellular behavior at the site of injury. Our lead program, OsteoVolt™, is a noninvasive bioelectronic bone regeneration technology designed to accelerate healing of fresh and nonunion fractures. Preclinical studies have demonstrated accelerated bone regeneration and fracture healing, and the program is advancing through large-animal validation toward a Class II 510(k) regulatory pathway. Beyond bone regeneration, Vira Regen is building its electrogenetic therapeutic modality as a platform technology for regenerative medicine, with potential applications across musculoskeletal disease, osteoporosis, osteoarthritis, oncology, and healthy longevity. Our vision is to create a new generation of medicines that don't simply treat disease—they use the body's own biological signaling systems to regenerate and restore function.

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Imbed Biosciences

Imbed Biosciences is a privately held medical device company that specializes in the development of advanced devices for the treatment of burns, ulcers, and soft-tissue repair. The company is committed to providing innovative solutions that improve patient care and outcomes through its patented Microlyte® Matrix technology.

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Lunai Bioworks Inc.

Lunai Bioworks Inc. is an AI-powered company at the intersection of drug discovery, diagnostics, and biodefense. The company integrates generative AI, proprietary neurotoxicity and chemical datasets, multi-omics, and high-throughput in vivo models to identify and validate therapeutic targets, biomarkers, and to safeguard against dual-use biosecurity risks. Lunai Bioworks partners with academia, industry, and government to advance safe and responsible AI-enabled biomedical innovation, spanning oncology, neurology, precision medicine, and countermeasure development for chemical and biological threats.

Member
Applied Research Associates, Inc. (ARA)

Applied Research Associates, Inc. (ARA) is a globally recognized scientific research and engineering company dedicated to solving critical national problems to improve safety, security, and quality of life. Founded in 1979, ARA is 100% employee-owned and offers innovative technologies and solutions across various sectors, including national security, infrastructure, health solutions, and energy and environment. The company is committed to delivering mission-critical solutions that exceed expectations and lead to new possibilities.

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Battelle

Battelle is an independent nonprofit organization dedicated to advancing science and technology to address the world's most pressing challenges. With over 90 years of experience, Battelle transforms knowledge into profound innovation, reinvesting its proceeds into scientific advancement and STEM education. The organization operates across various markets, including health, national security, environment, infrastructure, and industry, providing solutions through limitless innovation and expertise in scientific and engineering disciplines.

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BlueHalo Labs, LLC

Since 2002, Bluehalo Labs has established itself as a key federal contractor capable of delivering sophisticated technological products and engineering services across multiple domains. Based in Albuquerque, New Mexico, the company provides a diverse range of engineering, research and development, and technological services, with a strong focus on areas including space superiority, directed energy, missile defense, C4ISR, cyber/intelligence, and advanced sensor systems. Through its federal contract awards, Bluehalo Labs has provided an extensive array of goods and services to various agencies, including the Department of Defense, Air Force, Navy, Army, and civilian agencies like Customs and Border Protection and the Federal Railroad Administration. The company's contract work spans multiple technological domains, including developing unmanned aerial systems, sensor pod systems, radar equipment, optical communications systems, battle management software, and advanced research initiatives.

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Kindeva Drug Delivery

Kindeva Drug Delivery is a contract development and manufacturing organization specializing in advanced drug delivery systems including pulmonary, nasal, injectable, transdermal, and intradermal therapies. Services range from formulation and analytical development to commercial-scale, Annex 1-compliant GMP manufacturing across global facilities. The company brings integrated expertise in regulatory strategy, device engineering, process and technology transfer, and quality assurance, with a focus on sustainable solutions such as low-GWP propellants and microneedle patch platforms. Kindeva supports complex, patient-centric, and environmentally optimized therapies from product conception through commercialization.

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Biophoundry

Biophoundry specializes in advancing scalable engineered phage-based solutions for therapeutics, diagnostics, and bio-molecular engineering. It is shifting the paradigm from phage discovery to phage design. Its team leverages expertise in synthetic biology, machine learning, and data science to accelerate the development of precision antibiotics and address critical healthcare challenges such as antimicrobial resistance.

Member
Institute for Human & Machine Cognition (IHMC)

The Institute for Human & Machine Cognition (IHMC) is a non-profit research institute within the Florida University System focused on advancing human capabilities through interdisciplinary research. IHMC develops technologies and systems in artificial intelligence, robotics, human-machine teaming, cognitive systems, distributed computing, human performance monitoring, and cyber-physical security, with major collaborations in defense, healthcare, aerospace, and education. The institute is internationally recognized for pioneering work in resilience, cognition, natural language processing, multiagent systems, human-centered design, and operational excellence. IHMC also partners in academic programs, such as the state’s first Ph.D. in Intelligent Systems and Robotics, to develop expertise for high-demand technology sectors.

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Texas Biomedical Research Institute

Texas Biomedical Research Institute (Texas Biomed) is a leading nonprofit biomedical research organization with more than 80 years of experience supporting the development of medical countermeasures for emerging and high-consequence infectious diseases. Texas Biomed provides comprehensive in-vitro and in-vivo preclinical research services supporting the discovery, development, and evaluation of vaccines, therapeutics, diagnostics, and other medical countermeasures from early discovery through preclinical proof-of-concept, efficacy, and translational research. Studies can be conducted under GLP or GLP-like quality frameworks, as appropriate to program stage and sponsor requirements, with integrated quality assurance and study compliance support. The Institute operates state-of-the-art ABSL-2, ABSL-3, as well as the only privately operated BSL-4 research facilities, together with the Southwest National Primate Research Center, enabling studies in small animal and nonhuman primate models under high-containment conditions. Texas Biomed has extensive expertise in virus propagation and characterization, antiviral and neutralization assays, molecular diagnostics, immunology, pathology, bioinformatics, animal model development, natural history studies, efficacy testing, pharmacology, and biomarker evaluation across a broad range of viral pathogens, including filoviruses, henipaviruses, arenaviruses, alphaviruses, flaviviruses, coronaviruses, hantaviruses, and other emerging and biodefense-relevant viruses. Pathogen expertise includes, but is not limited to, Ebola virus (EBOV), Sudan virus (SUDV), Bundibugyo virus (BDBV), Marburg virus (MARV), Nipah virus (NiV), Lassa virus (LASV), Junín virus (JUNV), Machupo virus (MACV), Western equine encephalitis virus (WEEV), Japanese encephalitis virus (JEV), West Nile virus (WNV), Dengue virus (DENV) and SARS-CoV-2. With decades of experience supporting Animal Rule programs and infectious disease research, Texas Biomed delivers integrated, high-quality preclinical solutions for government, industry, and academic partners developing medical countermeasures for BSL-2, BSL-3, and BSL-4 pathogens.

Member
University at Buffalo (UB)

The University at Buffalo is a leading public research university and flagship of the SUNY System, recognized for its innovative research and commitment to societal impact. It aims to transform scientific and technological breakthroughs into global impact, addressing complex challenges through interdisciplinary collaboration.

Member
BioMojo LLC

BioMojo LLC is a biomedical performance solutions company based in Research Triangle Park, North Carolina. It creates integrated software and hardware solutions to improve human performance, decision-making, knowledge management, resilience, and mission-critical task execution for complex, high-consequence environments. The company leverages advancements in various technologies to enhance the speed, safety, and efficiency of human operators in high-stakes situations.

Member
University of California San Francisco

UC San Francisco is a leading university dedicated to advancing health worldwide through preeminent biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. With a commitment to public service, UCSF aims to innovate health care approaches for vulnerable populations and train the next generation of health professionals.

Member
MaXentric Technologies

MaXentric Technologies is a privately held company that designs and manufactures high-performance electronic solutions for the defense, medical, and commercial industries. Founded in 2003, MaXentric develops compact sensing, monitoring, and communications platforms that support patient assessment, physiological monitoring, and continuous care in austere far-forward environments. This includes advanced medical monitors, contactless vital-sign sensing, ingestible and self-powered biosensor platforms, and automated health data systems. Our company’s long history in RF, embedded, and signal-processing technologies underpin much of our medical technologies. With multidisciplinary teams across three U.S. locations, MaXentric combines hardware, firmware, signal processing, and user-interface development to move innovative medical technologies from concept to deployable systems.

Member
University of Texas Health Houston

UTHealth Houston is Texas’ resource for health care education, innovation, scientific discovery, and excellence in patient care. Since 1972, UTHealth Houston has been dedicated to educating the next generation of health care professionals, advancing biomedical research and public health, and providing exceptional care to communities. With half a century of experience, it is one of the nation’s most comprehensive academic health centers, committed to advancing the quality of human life through education, research, and clinical practice.

Member
4M Therapeutics

4M Therapeutics is a biotechnology company specializing in the discovery and development of targeted therapies for neuropsychiatric and neurodegenerative diseases such as bipolar disorder and Alzheimer's disease. Leveraging a human brain cell platform derived from induced pluripotent stem cells, the company advances small molecule and peptide drug candidates that modulate pathways involved in neuronal health. 4M Therapeutics integrates biomarker-driven drug development and strong academic collaborations to enable predictive and safe preclinical drug discovery, aiming to advance targeted CNS therapies with improved safety and efficacy profiles.

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The University of North Carolina at Chapel Hill

The University of North Carolina at Chapel Hill, the nation’s first public university, is dedicated to teaching, research, and public service. It aims to serve North Carolina, the United States, and the world by fostering a diverse community of students and preparing them to become leaders. With a commitment to excellence, UNC-Chapel Hill invests in knowledge and resources to enhance learning and improve the quality of life for all people in the state. The university is recognized for its innovative teaching, groundbreaking research, and dedication to public service, continuing a legacy that began in 1789.

Member
Xense Inc.

Aiming to minimize radiology error of 30% in healthcare delivery, XENSE 's Meta CT /AI  technology offers accurate standardized real time 3D imaging & 3D physical model for healthcare delivery of critical illnesses with ultralow x-ray radiation,  replacing  traditional CT , fluoroscope, general x ray, densitometer and other medical x modalities and related AI solutions  used in prediction, diagnosis and intervention guidance with one AI powered compact device with higher performances previously not possible.  With initial fundings from NASA and Department of Transportation, based on 30+ years of R & D and effort of two generations of engineers/physicist/molecular biologist from MIT,  Harvard Medical School, Columbia University and Boston University, the first Meta CT / AI aims to  minimize radiology errors, dramatically reduce radiation exposure, significantly lowering costs for the healthcare delivery and minimizing time to diagnosis, intervention & wellness. XENSE has filed 70+ and been granted multiple patents in imaging hardware, algorithms, AI and supporting technologies, though its primary products are currently in development and not yet FDA approved for commercial use.

Member
DefenSight Pty Ltd

DefenSight Pty Ltd, based in Australia, provides automated, auditable biological intelligence leveraging advanced imaging analytics. Originating from academic research in high-content imaging and infectious diseases, the company develops AI-enabled analytical platforms for defence, biosecurity, and translational research, supporting rapid, defensible decision-making. Its containerised analytical solutions focus on per-cell feature extraction, quantitative phenotyping, and audit-ready outputs—delivering capabilities for hazard assessment, countermeasure evaluation, and assay qualification in both laboratory-controlled (BSL-2/3) and field settings.

Member
Luna Labs

Luna Labs is a world-class technology and product development resource for the defense and healthcare industries. Collaborating across our core capabilities in Advanced Materials, Engineered Systems, and Biotechnology, our teams generate solutions for the most demanding environments and customers to save time, save money, and save lives. We partner with universities, government labs, and other world class companies to explore technological feasibility of new ideas, align technologies with customer needs, and generate solutions. Working with a robust global network of manufacturers, suppliers, licensees, and distributors, Luna Labs develops everything from small-scale prototypes up to market-ready products.

Member
Tunnell Government Services, Inc.

Tunnell Government Services, Inc. is a subsidiary of Tunnell Consulting, Inc., dedicated to providing professional services to government agencies. The company focuses on transforming organizations to achieve sustainable results and fulfill agency missions. With expertise in public health preparedness, biodefense lab support, and scientific project portfolio management, Tunnell Government Services partners with government organizations to address the greatest threats to public health and enhance organizational performance.

Member
RTM Vital Signs LLC

RTM Vital Signs LLC is a Philadelphia-based medical device company focused on transforming healthcare from reactive and hospital-centered to preventive, proactive, evidence-based, and person-centered. Specializing in real-time sensing, monitoring, and analysis of critical health information, RTM Vital Signs targets cardiovascular and respiratory health. The company leverages proprietary, cost-effective monitoring technology, advanced sensors, and AI-driven diagnostic algorithms to provide continuous, real-time health status tracking for both hospital and ambulatory patients. Their mission is to enable better health outcomes, lower costs, and improve patient and staff experiences through innovative wearable devices and continuous monitoring solutions. RTM's patented solutions are designed for seamless integration with smart devices and wearables, supporting timely diagnosis, predictive analytics, and improved telemedicine capabilities. Their technology also addresses key public health challenges such as hypertension, respiratory compromise, and opioid-induced respiratory depression, with applications extending to fitness, industrial safety, and veterinary medicine.

Member
BiosYnth s.r.l.

BiosYnth s.r.l. is a biotechnology firm specializing in the research, development, and innovation of bacterial and viral vaccine platforms. With over 40 years of expertise, the company focuses on glycoconjugate, nanostructured vector, and synthetic peptide technologies to address invasive infectious diseases and antibiotic resistance. Operations comply with GLP and GMP standards and are supported by a robust patent portfolio and international collaborations.

Member
University of California, Los Angeles

UCLA is a leading public research university located in Los Angeles, California. It is renowned for its commitment to the creation, dissemination, preservation, and application of knowledge for the advancement of global society. With a rich history of academic and athletic excellence, UCLA offers a comprehensive environment that supports both academic and personal growth. The university is dedicated to fostering innovation and making a significant impact on the world through groundbreaking research and transformative practices.

Member
Kilobaser (MABEAL GmbH)

Kilobaser develops benchtop DNA and RNA synthesizer platforms that enable decentralized, on-demand synthesis of custom oligonucleotides for scientific research, diagnostics, and data storage. Their technology leverages microfluidic chips and cartridge-based reagent delivery, automating solid-phase synthesis processes in a user-friendly system. Kilobaser's mission is to democratize access to nucleic acid synthesis, supporting rapid prototyping, molecular biology workflows, and emerging fields like DNA data storage.

Member
CFD Research Corporation

CFD Research Corporation specializes in engineering simulations, advanced prototypes, and innovative designs for aerospace, defense, life sciences, materials, energy, and other industries. The company is committed to delivering innovative technologies, services, and products to empower customers for success, transforming the future through innovative technology solutions.

Member
Epicore Biosystems

Epicore Biosystems is a digital health company specializing in biowearables for non-invasive monitoring of hydration, metabolic health, and stress through sweat analysis. Their solutions support industrial workers, athletes, and clinical researchers by converting sweat biomarkers and physiological data into actionable insights for real-time health, safety, and performance management. The company combines expertise in data science, material science, and biomedical engineering to create validated, user-centric wearable technologies, and partners with organizations across healthcare, academia, industry, and public health sectors.

Member
Vanderbilt University School of Engineering

The Vanderbilt School of Engineering is a globally recognized academic and research institution dedicated to producing leaders and innovators in engineering. With a commitment to solving grand challenges, the school offers a diverse range of undergraduate and graduate programs across multiple engineering disciplines, fostering a culture of collaboration and excellence.

Member
Medical College of Wisconsin

The Medical College of Wisconsin (MCW) is dedicated to transforming healthcare through innovative education, research, and patient care. With a focus on academic medicine, MCW aims to improve the health of communities by fostering a collaborative learning environment that integrates medical education with groundbreaking research and comprehensive patient care.

Member
Headache Sciences Inc.

Headache Sciences Inc. is a clinical artificial intelligence company pioneering the diagnosis and monitoring of headache disorders, with a primary focus on migraine. Leveraging advanced EEG (electroencephalography) technology and machine learning, the company has developed the world's first objective test for migraine, aiming to address the global challenge of underdiagnosis and misdiagnosis. Their mission is to provide practitioners with innovative tools to improve diagnostics, monitoring, and treatment of headache-related neurogenic and neurodegenerative disorders. With a vision of translating brain electrical activity into a comprehensive suite of diagnostic and monitoring services, Headache Sciences Inc. stands at the forefront of Software as a Medical Device (SaMD) innovation, offering hope through discovery.

Member
Sciperio Inc.

Sciperio Inc. is a pioneering research and development company at the forefront of physical and biological innovation. With a transdisciplinary engineering approach, Sciperio excels in mechanical, chemical, electrical, and biological sciences, pushing the boundaries of traditional scientific fields to develop next-generation technologies. The company is committed to advancing technology for the betterment of humankind, with core capabilities in additively manufactured electronics, mechatronics, machine learning, printed electronics, and biological engineering. Sciperio's mission is to research new concepts and develop technologies that connect people, mobilize businesses, and enhance life through advanced technology.

Member
Imperial College London

Imperial College London is a world-leading university focused on science, technology, engineering, medicine, and business. It is dedicated to addressing global challenges through innovative research and education, fostering a diverse and inclusive community of students and staff.

Member
UC San Diego

The University of California San Diego (UC San Diego) is a leading public research university located in La Jolla, California with over $1.79B in research expenditures. Known for its innovative and interdisciplinary approach, UC San Diego offers a wide range of undergraduate, graduate, and professional programs across various fields. UC San Diego is recognized for its contributions to research and innovation, particularly in areas such as national defense, energy, data science, climate science, health innovation, and artificial intelligence. We also have the nation's first undergraduate program promoting projects and start up devoted to National Security Innovation (4iNS).

Member
Biobeat

Biobeat is a global leader in wearable remote patient monitoring technology, revolutionizing hypertension diagnosis and management through innovative, non-invasive, cuff-less blood pressure monitoring systems. Their mission is to ensure all hypertension patients are monitored and managed effectively, empowering healthcare providers with accurate, real-time data to optimize patient care. Biobeat leverages proprietary patented PPG sensor technology and advanced data analytics to deliver continuous, medical-grade monitoring solutions that enhance clinical decision-making, improve patient compliance, and enable proactive interventions. With FDA-cleared and CE-certified devices, Biobeat is committed to transforming healthcare delivery, supporting both in-hospital and home-based care, and driving better patient outcomes worldwide.

Member
MedTech Innovator

MedTech Innovator is the world's largest accelerator for medical device, digital health, and diagnostic companies. Their mission is to improve patients' lives by accelerating the growth of companies transforming healthcare worldwide. They offer programs and resources to support innovators in the medtech industry, including webinars, fellowships, and strategic partnerships.

Member
Chronic Trace, Inc.

Chronic Trace develops a research-stage platform that turns video from a commodity smartphone into objective, baseline-relative indices of brain function. A single short capture fuses involuntary signals (oculomotor and postural) with task-based measures (cognitive and reaction) into one calibrated index, the Trace Score, for decision support. The live focus today is concussion and mild TBI; the same architecture is patent-staked to extend toward stroke triage, psychiatric, and neurodegenerative monitoring. The platform is in active validation, backed by 15 U.S. patents pending, with encrypted data handling at rest and in transit. It is decision-support and research-stage, not a cleared medical device, and its outputs are intended for interpretation by qualified health professionals.

Member
Triton Systems, Inc.

Triton Systems is dedicated to developing innovative products that address the most challenging problems faced by customers, particularly in defense, medical, and environmental sectors. With over thirty years of experience in research and development for the U.S. Department of Defense, Triton combines innovative solutions with emerging technologies to create impactful products. The company is also focused on clean energy technologies and has established partnerships to enhance U.S. manufacturing capabilities. Triton is actively engaged in developing neurosymbolic AI, advanced materials for military applications, and biofabrication techniques, positioning itself at the forefront of technological innovation.

Member
Houston Methodist Academic Institute

Houston Methodist Academic Institute integrates advanced clinical research, education, and healthcare innovation with a focus on translating scientific discoveries into improved patient outcomes. The institute offers accredited graduate and postgraduate medical education, supports interdisciplinary research in major areas such as cancer, cardiology, neuroscience, transplant medicine, and regenerative medicine, and provides extensive infrastructure for digital health and medical technology development. Training and fellowship programs span from medical residencies and fellowships to doctoral and research-oriented positions, supported by collaborations with leading academic and industry partners. The institute leverages core technology platforms, simulation centers, and comprehensive educational pathways to foster future leaders in medicine and biomedical research.

Member
Sense Neuro Diagnostics

Sense Neuro Diagnostics is dedicated to developing non-invasive technology for the rapid detection and monitoring of stroke and traumatic brain injuries (TBI). Their mission is to improve patient outcomes by providing real-time assessments that enhance the efficiency of care in emergency situations.

Member
Nutromics

Nutromics develops minimally invasive, wearable biosensor solutions for real-time, continuous monitoring of molecular biomarkers and therapeutic drugs. The company's platform technology integrates DNA-based electrochemical sensors with microneedles, aiming to transform current diagnostic practices by enabling continuous molecular measurements directly from patients. Nutromics is focused on therapeutic drug monitoring and broader critical care indications, with ongoing clinical studies and regulatory development. Its interdisciplinary team operates from Melbourne and San Diego, supported by collaborations with leading academic partners.

Member
ARIScience

ARIScience is at the forefront of drug discovery, leveraging a unique combination of AI, quantum chemistry, computer vision, and biochemistry to develop novel small molecule drugs. Their mission is to reduce the burden of human disease by discovering therapeutics that interrupt disease pathways. With a focus on neurodegenerative, inflammatory, and infectious diseases, ARIScience employs cutting-edge in silico methods to efficiently identify and optimize drug candidates. Their commitment to innovation and collaboration with leading institutions positions them to make a significant impact on human health. ARIScience is creating value in two ways: Value 1: ARIScience is developing small molecule assets targeting respiratory depression, cutaneous burn and radiation injuries, antivirals for EBOV and DENV, bacteriostatic antibiotic targeting Staph aureus. Value 2: It's novel AI driven quasi quantum chemistry (AI+QQ) small molecule discovery platform for precision protein inhibition and potentiation.

Member
X-trodes

X-trodes is a pioneering company in wearable electrophysiological monitoring, dedicated to liberating data collection from traditional lab settings. Their mission is to enhance healthcare quality, accessibility, and efficiency by enabling real-life, medical-grade monitoring through innovative, flexible skin patches and advanced sensor technology. Rooted in over a decade of research at Prof. Yael Hanein’s Neuro Engineering laboratory, X-trodes empowers healthcare practitioners, patients, and researchers with actionable insights, personalized treatments, and improved outcomes. Their technology is validated by extensive scientific research and is designed for use in diverse environments, making healthcare more inclusive and accessible for all. X-trodes emphasizes collaboration with industry leaders and research centers, user-friendly design for self-application, and the development of robust data analysis algorithms to ensure high-quality, actionable data in real-world settings.

Member
The University of Texas Southwestern Medical Center

UT Southwestern Medical Center is a premier academic medical institution dedicated to advancing medical science and improving health care through excellence in education, research, and patient care. The center is renowned for its collaborative environment that fosters innovation and discovery, housing distinguished faculty including Nobel Laureates. UT Southwestern is recognized for its groundbreaking research, comprehensive educational programs, and commitment to patient care, serving millions annually across its facilities.

Member
University of Connecticut Health Center

UConn Health is a vibrant, integrated academic medical center that is entering an era of unprecedented growth in academics, research, and clinical care. The campus hosts the Schools of Medicine and Dental Medicine with their respective graduate research programs, medical and dental clinics, and the UConn John Dempsey Hospital, rated as one of the World’s Best Hospitals for Infection Prevention and Patient Experience, and one of America’s Best-in-State Hospitals by Newsweek for the past four years. Recent investments in infrastructure, including new construction and renovated laboratory and teaching spaces, demonstrate a commitment to providing our faculty with access to the best possible infrastructure for scientific discovery, supporting Connecticut's and our region's need for innovation in service of our patients, transformative research, and society. We empower faculty, students, and industry partners to advance solutions that benefit Connecticut and the world, driving innovation, discovery, and societal impact through robust partnerships, state-of-the-art facilities, and a collaborative environment.

Member
Stanford University

Stanford University, founded nearly 150 years ago, is dedicated to educating students for lives of leadership and contribution with integrity. The university emphasizes advancing fundamental knowledge, cultivating creativity, and pioneering research for effective clinical therapies, while also focusing on societal impact and solutions.

Member
The Geneva Foundation

The Geneva Foundation is a 501(c)3 nonprofit established in 1993, dedicated to advancing military medicine through research, development, and education. With a commitment to ensuring optimal health for service members and the communities they serve, Geneva collaborates with various partners to drive innovative medical research and improve healthcare outcomes.

Member
Moberg Analytics

Moberg Analytics is pioneering the future of neuromonitoring with the first and only AI Ecosystem for neurocritical care. The company leverages AI, machine learning, and next-gen analytics to enhance patient care and data management in neurocritical care settings, focusing on traumatic brain injury (TBI) and other neurological conditions.

Member
Fluxion Therapeutics

Fluxion Therapeutics is focused on advancing pre-clinical drug discovery by integrating real-time electrophysiology data with artificial intelligence for the analysis of ion channel activity. The company specializes in large-scale electrophysiological data collection, automated patch-clamp analytics, and the development of machine learning models for drug safety and toxicology. Its mission is to unlock dynamic, functional insights from live cell signals, offering a new 'omics' layer for cellular physiology in drug R&D.

Member
SPOC Biosciences

SPOC Biosciences is a life sciences technology company focused on advancing proteomics through high-plex biosensor chip platforms. The company enables high-throughput, cost-effective protein production and deep characterization of protein interactions using techniques such as cell-free expression and multiplexed SPR biosensing. Their platform accelerates drug discovery, AI-driven drug design, biomarker identification, diagnostics, antibody screening, and vaccine development by generating scalable, high-resolution kinetic datasets suitable for advanced analytics and AI model training.

Member
Columbia University

Columbia University is a leading Ivy League research university in New York City, founded in 1754. It comprises undergraduate and graduate programs across 17+ schools, a world-renowned medical center, and nearly 200 research centers and institutes. The Global Alliance for Preventing Pandemics (GAPP) in the Mailman School of Public Health is dedicated to capacity building through workforce development and democratization of technology to provide public health professionals in the Global South every opportunity to independently identify and contain pathogen outbreaks. GAPP focuses on sharing sustainable technologies and best technical practices involving sequencing, serological, and rapid diagnostics tools so public health teams are poised to achieve their very different goals addressing their varied and evolving needs. GAPP works closely with the US CDC, NIAID, WHO, GOARN, foundations dedicated to global health and medical equity, and local and regional ministries of health and education to address human health, and the ministries of livestock and fisheries to help address food security while fostering a culture of the open sharing of data.

Member
Axiom Management Solutions

Axiom Management Solutions is a veteran-owned business offering consulting and service support across all stages of medical device development. Axiom's core philosophy: Early-stage medtech innovators deserve to own their development journey without the burden of heavy overhead or restrictive partnerships. Axiom empowers developers to bring their vision to life with precision, flexibility and expert support. The company specializes in helping innovators navigate regulatory requirements, develop prototypes, establish quality management systems, and take medical devices from concept to commercialization.

Member
CuriRx

CuriRx is a minority woman-owned Contract Research, Development, and Manufacturing Organization (CRDMO) based in Massachusetts. The company provides comprehensive solutions for drug development with expertise in bioprocessing, formulation development, analytical testing, and manufacturing support. CuriRx offers services across the therapeutic development spectrum, including customized solutions, collaboration, cutting-edge analytical methods, and process optimization to accelerate client projects from discovery to clinical and commercial stages.

Member
Neurable

Neurable develops non-invasive brain-computer interface technology, integrating advanced EEG signal processing, AI analytics, and secure data infrastructure into wearable devices for real-time cognitive and brain health monitoring. The focus is on providing accessible, research-grade mental wellness and cognitive insights through user-friendly, privacy-first devices for daily consumer, clinical, and research settings.

Member
Signature Science, LLC

Signature Science, LLC is a multidisciplinary applied science and technology company dedicated to solving the toughest forensic, biosecurity, and public health challenges. Serving both government and commercial clients, Signature Science combines scientific rigor with proven quality assurance to enhance the credibility and defensibility of programs in national security, public safety, and health security. The company is recognized for its innovation, technical excellence, and commitment to advancing the state-of-the-art in forensic science, genomics, and biosecurity technologies. Signature Science also offers advanced bioinformatics and microbiome analysis services, empowering clients with data-driven insights to address emerging threats, pandemics, and bioterrorism. The company is a subsidiary of Southwest Research Institute and is committed to community engagement and workforce development.

Member
EROS Technologies LLC

Veteran-owned Small Business (VOSB) with core capabilities in supply chain technologies and systems design. Patent pending for a nanotechnology-based, autonomous, non-intrusive inspection (NII), multi-target analyte sensor. Founder/CEO doctoral dissertation-based design of an innovative, rural area, agricultural business supply chain system technology cooperative (SmartHub).

Member
Finch AI

Finch AI specializes in advanced data science and AI-driven analytic platforms that transform high-volume structured and unstructured text into actionable intelligence. By leveraging knowledge graphs, retrieval-augmented generation, domain-tailored models, and multimodal data fusion—including geospatial data—Finch AI enables real-time insights, risk assessment, and decision support for sectors including government, finance, law enforcement, and academia. The company maintains a quality-centric development process, emphasizing model validation, monitoring, and explainability across applications such as intelligence, due diligence, and situational awareness.

Member
Texas A&M Engineering Experiment Station (TEES)

The Texas A&M Engineering Experiment Station (TEES) is a state agency and part of the Texas A&M University System, dedicated to improving lives through engineering research, workforce development, and technology transition. TEES collaborates with industry, academia, and government to provide innovative solutions to global technical challenges.

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Moonrise Medical

Automated Portable Ultrasound for Rapid Vascular Assessment in Combat Casualty Care: Moonrise Medical Inc.

Moonrise Medical Inc. is developing an automated portable ultrasound system for rapid vascular assessment and real-time blood-flow monitoring in combat casualty care. The project is supported through MTEC Award No. 24-01-MPAI-149.

NIRSense

Rugged Physiological Monitoring for the Modern Warfighter: NIRSense

Under MTEC-21-10-NavyMultiTopic, NIRSense is advancing its tactical jet physiological monitoring technology for broader Navy applications. The project focuses on ruggedized, wireless physiological sensors that can provide reliable, real-time insight into warfighter health and performance in demanding operational environments.

Safi Biotherapeutics

Next-Generation Manufactured Red Blood Cells for Extended Battlefield Blood Supply: Safi Biotherapeutics

Safi Biotherapeutics is developing manufactured red blood cells (mRBCs) with extended shelf life to improve battlefield transfusion readiness and emergency trauma care.

Non-Invasive Glymphatic (GF) Monitoring and Recovery Optimization for Warfighter Cognitive Readiness

Applied Cognition is developing non-invasive glymphatic monitoring and recovery technologies to enhance warfighter cognitive readiness, resilience, and sleep recovery.

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