SynVivo
SynVivo is a cell-based microfluidic organ-on-chip platform dedicated to providing realistic microenvironments for real-time cellular behavior, drug delivery, and drug discovery. Their proprietary microfluidic chips support microvascular networks that simulate tissue circulation, supporting cells that retain biological phenotypes similar to in vivo tissues. They focus on applications in personalized medicine, oncology, neuroscience, inflammation, and toxicology, offering models, microfluidic chips, instruments, and accessories to facilitate advanced research and development in the life sciences.
Industries
Nr. of Employees
small (1-50)
SynVivo
601 Genome Way, STE 2023E, Huntsville, Alabama, 35806
Patents
Products
3D tissue and organ-on-chip model suites (BBB, tumor, inflammation, lung ALI, toxicology)
Pre-configured microfluidic 3D tissue models representing blood–brain barrier, vascularized tumor microenvironment, inflammation assays, air–liquid interface lung models, and toxicology co-cultures for perfused assays and imaging.
Microfluidic chips in multiple geometries
Fabricated microfluidic devices in linear, bifurcating, idealized, and mapped microvascular network geometries to model distinct hemodynamic conditions for particle adhesion, transport, and cell migration studies.
Flow instrumentation and laboratory hardware for perfused assays
Instruments and controllers commonly used with microfluidic chips, including syringe pumps, pneumatic primers/controllers, stage-top incubators, and cell impedance analyzers to support controlled flow and environmental conditions during experiments.
Consumable accessories for flow-based assays
Consumables required to operate flow-based microfluidic assays such as laboratory tubing, clamps, syringes with Luer connections, and blunt-tip needles supplied in pack quantities.
3D tissue and organ-on-chip model suites (BBB, tumor, inflammation, lung ALI, toxicology)
Pre-configured microfluidic 3D tissue models representing blood–brain barrier, vascularized tumor microenvironment, inflammation assays, air–liquid interface lung models, and toxicology co-cultures for perfused assays and imaging.
Microfluidic chips in multiple geometries
Fabricated microfluidic devices in linear, bifurcating, idealized, and mapped microvascular network geometries to model distinct hemodynamic conditions for particle adhesion, transport, and cell migration studies.
Flow instrumentation and laboratory hardware for perfused assays
Instruments and controllers commonly used with microfluidic chips, including syringe pumps, pneumatic primers/controllers, stage-top incubators, and cell impedance analyzers to support controlled flow and environmental conditions during experiments.
Consumable accessories for flow-based assays
Consumables required to operate flow-based microfluidic assays such as laboratory tubing, clamps, syringes with Luer connections, and blunt-tip needles supplied in pack quantities.
Services
Custom development and validation of assays and 3D tissue/organ-on-chip models for drug screening, mechanism-of-action studies, and toxicology.
Educational workshops and hands-on training on protocols, instrumentation, and best practices for running microfluidic organ-on-chip assays.
Custom development and validation of assays and 3D tissue/organ-on-chip models for drug screening, mechanism-of-action studies, and toxicology.
Educational workshops and hands-on training on protocols, instrumentation, and best practices for running microfluidic organ-on-chip assays.
Expertise Areas
- Organ-on-chip and perfused 3D tissue model development
- Microvascular network engineering and endothelial biology under flow
- Tumor microenvironment modeling and preclinical drug delivery assessment
- Blood–brain barrier modeling and functional permeability testing
Key Technologies
- Microfluidics for perfused cell culture
- Organ-on-chip platforms
- Microfabrication of PDMS and similar polymers
- Endothelialized vascular network culture
News & Updates
SynVivo will participate in SHOCK 2025 in Boston, showcasing their organ-on-chip capabilities.
SynVivo will attend BIO International 2025 in Boston, presenting their latest research and models.
Participation in the MPS World Summit 2025 to discuss advances in microphysiological systems.
Research on a peptide that enhances blood-brain barrier integrity in mice and humans.
Study identifying neutrophil phenotypes associated with sepsis severity.
Development of a chip to evaluate how monoclonal antibodies are absorbed subcutaneously in humans.
SynVivo will participate in SHOCK 2025 in Boston, showcasing their organ-on-chip capabilities.
SynVivo will attend BIO International 2025 in Boston, presenting their latest research and models.
Participation in the MPS World Summit 2025 to discuss advances in microphysiological systems.
Research on a peptide that enhances blood-brain barrier integrity in mice and humans.
Study identifying neutrophil phenotypes associated with sepsis severity.
Development of a chip to evaluate how monoclonal antibodies are absorbed subcutaneously in humans.