Emulate

Consumable kits providing chips and reagents for laboratories that supply their own cells to build organ-chip models.

Organ-Chip model to study neurovascular unit physiology, disease, and drug candidate effect.

Contains FUJIFILM Cellular Dynamics iCell GABANeurons, iCell Astrocytes 2.0, iCell Pericytes, and iCell Microglia, as well as Emulate's proprietary BMECs manufactured by FUJIFILM Cellular Dynamics. Also contains custom media and Chip-R1 Rigid Chips.

Brain Bio-Kit containing 12 stretchable chips and essential components for recreating the human brain and blood-brain barrier.

Brain Bio-Kit containing 6 stretchable chips and essential components for recreating the human brain and blood-brain barrier.

Capable of 96 Organ-Chip samples per run, AVA unleashes unprecedented experimental power to rank order lead candidates and optimize the preclinical safety and efficacy of your drug candidates.

An advanced organ-chip BioKit integrating the AVA Emulation System with the Liver-Chip S1 model for human-relevant drug discovery.

With its versatile modeling capabilities and 12-Chip capacity, Zoë is ideally suited for developing functional models of human biology and disease to identify and validate drug targets.

Culture module designed to sustain the life of cells within Organ-Chips by providing dynamic media flow and mechanical forces.

A research kit combining the Chip-S1 and Zoë-CM2 Culture Module for organ-chip emulation systems and modeling applications.

Includes chips and reagents for use with customer cell sourcing.

Hub module that provides a simple solution for installing and operating the Zoë Culture Module within the laboratory environment.

A module that connects to standard lab outputs and provides gas, power, and stretch to up to four Zoë Culture Modules.

Organoid-based model to investigate mechanisms of colon inflammation and barrier disruption and evaluate the efficacy of anti-inflammatory drug candidates.

Contains biopsy-derived primary colonic organoids, colonic microvascular endothelial cells, and Chip-S1 Stretchable Chips.

Portable module that houses the organ-chip, supplies media, and enables compatibility with microscopes and standard laboratory analysis equipment.

The interface between Organ-Chips and Zoë that houses the chip, contains media and effluent, and enables compatibility with laboratory equipment.

Primary organoid-based model of the human small intestine to study drug absorption.

Contains biopsy-derived primary duodenal organoids, small intestinal microvascular endothelial cells, and Chip-S1 Stretchable Chips.

Available in co- and quad-culture configurations that include primary human hepatocytes, liver sinusoidal endothelial cells, Kupffer cells (quad only), and stellate cells (quad only).

The Chip-Array™ Basic Research Kit contains all the non-biological components required to run a 96-sample experiment on the AVA Emulation System. It integrates 12 individual Organ-Chip Emulations into a single, high-throughput consumable made from low-drug-absorbing materials.

The Chip-S1 Basic Research Kit includes the essential components needed to create a vast array of Organ-Chip models and is available in multiple quantities to meet various study needs.

Model complex 3D tissues with the ability to directly apply topical or aerosolized drugs. A revolutionary design empowering high-throughput Organ-Chip studies.

Human-relevant organ-on-a-chip models that recreate complex disease biology, evaluate ADME properties, and assess human safety liabilities.

Improve precision in ADME and toxicology applications with a low-drug-absorption profile.

Available in co- and quad-culture configurations that include primary human hepatocytes, liver sinusoidal endothelial cells, Kupffer cells (quad only), and stellate cells (quad only).

Our BioKits provide the essential components needed to create validated, functional organ models, including Organ-Chip consumables, pre-qualified human cells, and chip activation reagents.

A comprehensive brochure detailing Emulate's portfolio of user-friendly Organ-Chip systems designed to incorporate Organ-on-a-Chip technology into drug discovery and development.

A research kit used for human emulation systems incorporating microfluidic organ-on-chip technology.

The Proximal Tubule Kidney-Chip S1 BioKit includes the essential components needed to create the Proximal Tubule Kidney-Chip S1—including Emulate qualified cells—and is available in multiple sizes to meet various study needs.

An Organ-on-a-Chip model used to study lung physiology, disease, and the effect of drug candidates, including evaluating treatments for viral infections such as COVID-19.

Co-culture human proximal tubule model to evaluate drug candidate toxicity at clinically-relevant concentrations.

Organ-Chip model supported by Emulate guidelines to understand bone marrow pathophysiology induced by drugs, radiation, or genetic mutations.

The Lymphoid Organ-Chip model supports the formation of lymphoid follicles with functional germinal centers similar to those found in secondary and tertiary lymphoid organs in vivo, enabling researchers to recapitulate human vaccine and adjuvant responses.

A novel and flexible workflow that enables researchers to model the holistic journey of CAR T-cell therapy from blood vessel to target in a vascularized cancer cell line model.

Organ-Chip model to study host-microbiome interactions and test new therapies.

A primary human Small Intestine-on-a-Chip containing epithelial cells isolated from healthy regions of intestinal biopsies, cultured on a porous membrane within a microfluidic device with human intestinal microvascular endothelium under flow and cyclic deformation.

Application-specific tool to quantify the migration of immune cells across the channels of Emulate Organ-Chips, such as the Colon Intestine-Chip.

General tool to calculate the permeability of the epithelial-endothelial barrier in Emulate Organ-Chips.

Application-specific tool to determine the appropriate dilution of adeno-associated virus (AAV), given the desired MOI, vector titer, and the number of chips.

Application-specific tool to analyze CAR T-cell recruitment, segmentation, and killing response in an Organ-Chip model.

Application-specific tools to simplify assay preparation and data analysis for the Emulate Compound Distribution Kit (CDK) protocol.