Biopico Systems, Inc.


Biopico Systems Inc. is dedicated to developing accurate biology models for precision medicine through innovative microfluidic technology. Their mission is to create functional organ tissues and multi-organ systems for therapeutic discoveries, drug testing, and organ repair, enabling better understanding of human physiology and disease.

Industries

biotechnology
manufacturing
marketing-2795

Nr. of Employees

small (1-50)

Biopico Systems, Inc.

188 Technology Dr, Suite G Irvine CA 92618


Patents

Fluidic array systems and testing for cells, organoids, and organ cultures

US-11807842-B2

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Microfluidic devices and methods for cell processing

US-10232371-B2

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Microfluidic devices and methods based on massively parallel picoreactors for cell and molecular diagnostics

US-9110026-B2

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Products

Multi-organ recirculation microfluidic system

A gravity-driven microfluidic system that enables passive unidirectional shear flow and programmable recirculation across multiple connected organ units to emulate physiological flow.

Glass-bottom multi-unit organ culture plate

Injection-molded disposable plate with glass bottoms and multiple multi-organ units (six-unit format referenced) designed for media recirculation and 3-D organ maturation from primary cells, cell lines, or iPSC-derived tissues.

Organotypic tissue constructs for repair and implantation studies

Engineered vascular and cardiac tissue constructs developed under microfluidic culture conditions for use in graft development and preclinical implantation research.


Services

Laboratory testing of compounds using barrier and multi-organ tissue models to determine transport characteristics, toxicity, and off-target effects.

Analytical workflows to sample culture media and perform LC‑MS to identify drug metabolites and biomarkers produced by specific organ units.

Expertise Areas

  • Multi-organ microfluidic culture
  • Organ-on-chip toxicology and ADME‑Tox
  • Tissue engineering and graft development
  • Barrier and blood–brain barrier modeling
  • Show More (4)

Key Technologies

  • Microfluidics
  • Gravity-driven unidirectional recirculation
  • Laplace fluidic-stop channels
  • 3D cell culture and organoids
  • Show More (6)

News & Updates

Participation in the Society of Toxicology's annual event.

Participation in the Society of Neuroscience's annual event.

Discusses the significance of fluidic shear stress in organ systems using OrganRX™ technology.

Details the use of liquid chromatography-mass spectrometry to analyze drug metabolism in OrganRX™ systems.

Research on drug testing models for Alzheimer’s disease using multi-organ systems.

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