Dynamic42
Dynamic42 GmbH is a biotech company specializing in organ-on-chip technology, developing human microphysiological systems for toxicity screening, drug development, disease modeling, and preclinical research. The company aims to support ethical, animal-free, and sustainable research practices, reduce animal testing, and advance personalized medicine through innovative biochip solutions and comprehensive training programs.
Industries
Nr. of Employees
small (1-50)
Dynamic42
Winzerlaer Straße 2, 07745 Jena, Germany
Patents
Method and devices for the in vitro production of arrangements of cell layers
US-10731119-B2
View Details
Method and devices for the in vitro production of arrangements of cell layers
US-10731119-B2
View DetailsProducts
Modular organ-on-chip platform
A modular platform combining microfabricated biochips, perfusion hardware and accessories to recreate physiological cell and tissue culture conditions including vascular perfusion and immune cell integration.
Low-adsorption microfluidic biochips
Microfabricated biochips offered as consumables for 3D and co-culture organ experiments, engineered for low compound adsorption, membrane customization and compatibility with perfusion and imaging workflows.
Developer kits and protocol packs
Starter kits and documentation to help laboratories set up organ-on-chip experiments, including consumables, stepwise protocols for sterilization, cell seeding, perfusion and standard assays.
Modular organ-on-chip platform
A modular platform combining microfabricated biochips, perfusion hardware and accessories to recreate physiological cell and tissue culture conditions including vascular perfusion and immune cell integration.
Low-adsorption microfluidic biochips
Microfabricated biochips offered as consumables for 3D and co-culture organ experiments, engineered for low compound adsorption, membrane customization and compatibility with perfusion and imaging workflows.
Developer kits and protocol packs
Starter kits and documentation to help laboratories set up organ-on-chip experiments, including consumables, stepwise protocols for sterilization, cell seeding, perfusion and standard assays.
Services
Fee-for-service experimental work including toxicity screening, lead optimization, antibody safety testing, ADME/PK profiling and custom in vitro model development using perfused microphysiological systems.
Two- to three-day hands-on workshops covering biochip handling, sterilization, cell seeding, perfusion setup, sampling, imaging and troubleshooting to enable participants to implement organ-on-chip methods in their laboratories.
On-demand instructional content including theoretical background and stepwise protocol videos for organ-on-chip laboratory procedures to support remote learning and scalable training.
Fee-for-service experimental work including toxicity screening, lead optimization, antibody safety testing, ADME/PK profiling and custom in vitro model development using perfused microphysiological systems.
Two- to three-day hands-on workshops covering biochip handling, sterilization, cell seeding, perfusion setup, sampling, imaging and troubleshooting to enable participants to implement organ-on-chip methods in their laboratories.
On-demand instructional content including theoretical background and stepwise protocol videos for organ-on-chip laboratory procedures to support remote learning and scalable training.
Expertise Areas
- Microphysiological systems (organ-on-chip) development
- Perfused vascularized co-culture and multi-organ integration
- Immunocompetent infection and host–pathogen modeling
- Preclinical toxicity, ADME/PK and antibody disposition profiling
Key Technologies
- Microfluidic perfusion systems
- Microphysiological systems (MPS) / organ-on-chip
- 3D cell culture and spheroid/organoid integration
- Vascularized co-culture models
News & Updates
Partnership announcement for distribution in the United States.
Development of a 3D tumour-on-chip model for realistic drug testing.
Development of an innovative three-organ system in collaboration with research partners.
Overview of organ-on-chip systems, their components, and workflows.
Summary of research areas where organ-on-chip technology can be applied.
Introduction to organ-on-chip technology and its potential to bridge 2D-cell-culture and animal experiments.
Partnership announcement for distribution in the United States.
Development of a 3D tumour-on-chip model for realistic drug testing.
Development of an innovative three-organ system in collaboration with research partners.
Overview of organ-on-chip systems, their components, and workflows.
Summary of research areas where organ-on-chip technology can be applied.
Introduction to organ-on-chip technology and its potential to bridge 2D-cell-culture and animal experiments.