Tissuse Gmbh


TissUse is a Berlin-based biotechnology company pioneering human-on-a-chip technology. Their mission is to develop innovative microphysiological systems that simulate human organs for drug development, safety evaluation, and personalized medicine, aiming to replace animal testing and streamline clinical trials.

Industries

biotechnology
product-design

Nr. of Employees

small (1-50)

Tissuse Gmbh


Products

Bench-top multi‑organ-chip controller devices

Bench-top devices that control and monitor microfluidic multi-organ chips, providing perfusion, pneumatic actuation and interfaces for chip operation and imaging. Device variants support manual and automated workflows.

Single-use multi-organ microfluidic chips (various organ configurations)

Single-use microfluidic chips designed to host one or multiple human organ models in defined arrangements for ADME, toxicity and efficacy assays. Chips are produced in cleanrooms, shipped filled with buffer and configurable to customer organ combinations.

Accessories and consumables for microphysiological systems

Supportive accessories and consumables such as tubing, tube adapters and heat support components used to operate devices and chips; consumable replacement and spare parts available.


Services

Custom assay development and contract services for safety and efficacy testing

Contracted development of flexible multi-organ assays for hazard identification, toxicity, efficacy and DMPK/ADME profiling using human tissue microphysiological systems.

Rapid prototyping and custom chip design service

Design and short‑turnaround production of custom microfluidic chip geometries and organ arrangements to meet specific assay requirements.

Maintenance and field application specialist support

Maintenance service contracts and field application specialist support covering consumable exchange and device performance optimization.

Protocols, training and user documentation

Provision of cultivation and assay protocols, publications and laboratory training (master classes) to support users in implementing chip-based experiments.

Expertise Areas

  • Microphysiological systems (organ-on-chip) development
  • Multi-organ assay design for ADME/DMPK and toxicity testing
  • Preclinical human disease modelling
  • Microfluidic device prototyping and manufacturing
  • Show More (4)

Key Technologies

  • Microfluidics
  • Multi-organ microphysiological systems
  • On-chip micro-pumps and perfusion systems
  • Vascularized organ models
  • Show More (5)

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