Conjugate Vaccines
Conjugate vaccines convert T-cell–independent capsular polysaccharide antigens into T-cell–dependent immunogens by covalent linkage to carrier proteins. This enhances immunologic memory, affinity maturation, and efficacy in infants and immunocompromised adults, reducing invasive disease from encapsulated pathogens such as Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae.
Technical Challenges
Heterogeneity of polysaccharide antigens complicates consistent conjugation and potency.
Thermostability and cold-chain dependence limit deployment in austere and prolonged-field-care environments.
Reduced immunogenicity in immunocompromised or heavily pre-exposed populations and elderly service members.
Manufacturing scale-up and batch-to-batch consistency for novel glycoconjugates remains resource-intensive.
Emerging Opportunities
Rapidly deployable, thermostable conjugate formulations suitable for austere settings and prolonged field care.
Platform technologies enabling fast design and clinical translation against emerging bacterial threats.
Improved carriers and adjuvant strategies to boost responses in immunosenescent and immunocompromised personnel.
Manufacturing approaches that reduce cost, increase throughput, and ensure consistent glycan presentation.
Current and Emerging Technologies in Conjugate Vaccines
Polysaccharide–Protein Conjugation Chemistry
Click chemistry, reductive amination, and linker chemistries improve site-specific conjugation to control glycan:protein ratios and presentation, enhancing reproducible immunogenicity.
Synthetic Oligosaccharide and Glycoengineering
Chemical synthesis and enzymatic glycoengineering produce defined oligosaccharides for precise vaccine antigens, reducing variability inherent in native polysaccharide extraction.
Carrier Protein Optimization & Novel Carriers
Alternatives to CRM197 and toxoid carriers, including recombinant proteins and nanoparticle scaffolds, aim to reduce carrier-induced immune interference and broaden T-cell help.
Nanoparticles, VLPs, and Multivalent Display
Virus-like particles and synthetic nanoparticle platforms present multiple glycan epitopes to mimic pathogen architecture, improving B-cell activation and enabling dose sparing.
Formulation, Adjuvants, and Thermostable Delivery
Lyophilized, single-dose, and adjuvanted formulations—including novel TLR and saponin-based adjuvants—support durable immunity and reduce cold-chain dependence for forward-deployed forces.
Importance to Military Medicine
Force Readiness and Outbreak Prevention
Prevention of invasive bacterial disease preserves operational capability and reduces mission-impacting morbidity during deployments and training.
Austere and Prolonged Field Care
Thermostable conjugates and single-dose strategies enable immunization where cold chain and evacuation are limited, protecting personnel in forward and prolonged-care settings.
Reduced Evacuation and Clinical Burden
Preventing vaccine-preventable bacterial sepsis and meningitis decreases medevac requirements and conserves scarce surgical and critical care resources.
Biodefense and Contingency Preparedness
Conjugate platforms can be leveraged for rapid response to bacterial threats and for improving prophylaxis in mass-casualty or outbreak scenarios.
Alignment with the MTEC Mission
Directly supports DoD readiness priorities by preventing infectious disease that undermines unit effectiveness.
Enables rapid translation of improved vaccine platforms—aligning with MTEC’s mission to accelerate medical technologies for Warfighters.
Addresses biodefense and outbreak resilience, a core MTEC portfolio area in infectious disease and force health protection.
Supports dual-use impact—civilian public health benefits accelerate acceptance and scale for military-relevant vaccines.
Dual-Use (Military + Civilian) Applications
Pre-deployment immunization programs to reduce mission-limiting bacterial disease.
Austere-point vaccination with thermostable conjugates during prolonged-field-care or expeditionary operations.
Rapid-response platform vaccines for emergent encapsulated-bacteria threats and biodefense scenarios.
Explore MTEC Members with Conjugate Vaccines Capabilities
MTEC members bring multidisciplinary strengths—glycochemistry, clinical vaccinology, biomanufacturing, and forward-deployment logistics—to advance conjugate vaccine candidates. Explore member profiles to identify partners for platform development, thermostable formulation, clinical trials under DoD constraints, and rapid scale-up for both military and civilian use.
68 Members with Conjugate Vaccines capabilities.
Georgia Southern University is a vibrant institution with over 26,100 students across three campuses in Statesboro, Savannah, and Hinesville. The university offers 132 degree programs at the associate, bachelor’s, master’s, and doctorate levels, emphasizing student success, community impact, and research excellence. With a commitment to inclusivity and engagement, Georgia Southern fosters a supportive environment for diverse learners, including military-affiliated and adult students. The university is dedicated to transforming lives through education and community engagement, aligning its programs with regional needs. Additionally, Georgia Southern provides accelerated pathways for students to fast-track their master's degrees, enhancing educational opportunities. The university also emphasizes career readiness and public impact research, preparing students for successful careers and contributing to community development.
STAT Therapeutics is focused on developing a drug- device combination for easy, rapid administration of intramuscular, life-saving medications by users in any setting, aiming to improve access and usability for acute emergency treatments such as pain, anaphylaxis, and seizures.
Auburn University Research & Economic Development is dedicated to advancing research and economic growth through a collaborative effort among its various colleges and departments. The organization focuses on fostering innovation, supporting faculty and student research, and facilitating partnerships with industry and government to address societal challenges and enhance the quality of life. Recent initiatives include the launch of the Team Science Series to promote interdisciplinary collaboration and the development of the Gulf Coast Engineering Research Station to address coastal environmental challenges.
The Institute for Integrative & Innovative Research (I3R) at the University of Arkansas is dedicated to pioneering solutions to complex societal challenges through convergence research. With a mission to advance research excellence and stimulate economic development, I3R focuses on deploying innovations at scale through collaboration across various sectors, including academia, industry, and government.
The University of Chicago is a prestigious urban research university committed to rigorous inquiry and intellectual freedom. Founded in 1890, it has produced numerous Nobel laureates and is known for its transformative education and groundbreaking research across various fields. The university fosters an inclusive and diverse learning environment, encouraging participation from all community members.
Boston University is a major research institution committed to leading breakthroughs across various disciplines. The Office of Research supports and advances research excellence, fostering collaboration among researchers, industry partners, and government leaders to address significant societal challenges.
Baylor University is a preeminent Christian research university committed to addressing the world's most meaningful challenges through top-tier research and scholarship. Recognized as an R1 research institution, Baylor focuses on infusing its distinct Christian mission into its research initiatives, fostering a commitment to excellence and innovation.
Base Pair Biotechnologies specializes in custom aptamer discovery and development for research, diagnostics, therapeutics, and industrial applications. The company leverages proprietary multiplex selection, advanced bioinformatics, and chemical modification techniques to develop high-affinity and selective nucleic acid aptamers. Base Pair enables affinity reagent development, biosensor design, and molecular detection for a broad range of targets and partners across academia and industry.
The Nanovaccine Institute, established at Iowa State University in 2017, is a national transdisciplinary research consortium focused on advancing nano-based technologies to treat and prevent diseases. The institute aims to revolutionize public health outcomes through the design and promotion of nano-based vaccines and therapeutics.
Smith+Nephew is a portfolio medical technology company focused on the repair, regeneration, and replacement of soft and hard tissue. The company aims to restore people's bodies and their self-belief by using technology to take the limits off living. With a commitment to medical education and improving patient outcomes, Smith+Nephew operates in over 100 countries and is dedicated to sustainability and community health. Their purpose is to promote health and wellbeing, not just through their products but also by ensuring a positive impact on society and the environment. Smith+Nephew is also committed to increasing diversity within the medical device industry through initiatives like the Orthopaedics for All global advisory board.
The University of Maryland, Baltimore (UMB) is Maryland’s public health, law, and human services university. It is dedicated to improving the human condition and serving the public good through education, research, clinical care, and service. UMB is the founding campus of the University System of Maryland and offers a wide range of professional degrees in health care, human services, and law.
The University of North Carolina Wilmington (UNCW) is a top doctoral and research institution located in Wilmington, North Carolina. Established in 1947, UNCW has grown to serve nearly 18,000 students and employs about 2,500 staff. The university is dedicated to providing a powerful academic experience that fosters creative inquiry, critical thinking, and thoughtful expression in a beautiful coastal setting. UNCW is committed to educational excellence, community engagement, and global connections, making it a vibrant part of the southeastern North Carolina community. UNCW also emphasizes the importance of freedom of expression and mutual respect within its diverse community.
CellBios is a biotechnology company specializing in the design, development, and manufacturing of single-use bioprocessing and medical device solutions for healthcare, biotechnology, and regenerative medicine sectors. The company operates GMP and ISO-certified cleanroom facilities, offering a comprehensive portfolio of cryopreservation products, bioreactors, fluid management systems, advanced packaging, and specialty devices. By leveraging expertise in extrusion, molding, assembly, sterilization, quality control, and regulatory compliance, CellBios provides customized, scalable solutions to support blood transfusion, cell and gene therapy, biologics manufacturing, and clinical workflows.
The University of Missouri-Kansas City (UMKC) is dedicated to transforming today's learners into tomorrow's leaders through innovative education, research, and community engagement. With over 125 academic programs, UMKC fosters a diverse and inclusive environment that empowers students to achieve their goals and make a positive impact in their communities.
Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world, dedicated to providing high-quality, patient-centered care. With a history of innovation spanning nearly 150 years, Mayo Clinic is committed to transforming healthcare through research, education, and compassionate care, ensuring that the best possible treatment is available to everyone.
Ambient Biosciences is a global leader in biostabilization, dedicated to eliminating cold chain reliance and improving global health equity through innovative biomolecule stabilization technology. Their patented Capillary-Assisted Vitrification (CAV) process enables room-temperature storage and shipping of sensitive reagents and biomolecules, offering a superior alternative to traditional lyophilization and cryopreservation. With a values-driven, diverse team of scientific experts and visionary leaders, Ambient Biosciences is committed to transforming laboratory operations, reducing costs and waste, and making life sciences more accessible and sustainable worldwide.
Micron Biomedical is a clinical-stage life science company and the leader in dissolvable microarray-based technology for needle-free delivery of vaccines and therapeutics. The company's mission is to radically expand access to treatments and vaccines, improve global health outcomes, and transform how vaccines and drugs are administered. Micron's proprietary technology enables painless, thermostable, and self-administered drug and vaccine delivery, eliminating the need for cold chain logistics and reducing infrastructure barriers. The company is recognized for its innovative approach to overcoming vaccine hesitancy and access challenges, and is rapidly advancing toward commercializing its technology for global impact. Micron partners with leading global health organizations and has secured significant funding to accelerate the development and commercialization of its needle-free solutions.
Temple University is Philadelphia’s only public university and a global center of academic excellence. It is classified as an R1 institution, indicating very high research activity, and offers over 600 academic programs across 17 diverse schools and colleges. The university is committed to providing accessible education that fosters positive change and prepares students to become leaders in their fields. Additionally, Temple emphasizes a vibrant campus life enriched by arts, culture, and a commitment to diversity and inclusivity. The university also promotes a tobacco-free environment to enhance the health and well-being of its community. Temple's athletics program further enhances student life, with 19 varsity teams competing at the NCAA Division I level, fostering school spirit and community engagement.
The Office of Sponsored Projects Administration (OSPA) at the University of Kentucky is dedicated to transforming tomorrow by streamlining grants and contracts. OSPA provides essential services to faculty and staff, including assistance with proposal preparation, award negotiation, and compliance with sponsor policies.
Southwest Research Institute (SwRI) is a nonprofit research and development organization that provides independent, premier services to government and industry clients. Founded in 1947, SwRI is committed to advancing science and technology to benefit humanity, focusing on innovative solutions that improve human health and safety. With a diverse range of technical divisions, SwRI addresses complex challenges in various fields including mechanical engineering, materials, aerospace, automotive, biomedical, and more.
BioFactura, Inc., based in Frederick, Maryland, is a biopharmaceutical company specializing in the development and commercialization of high-value biosimilars, biodefense medical countermeasures, and novel drugs. Leveraging its proprietary StableFast™ Biomanufacturing Platform, BioFactura delivers faster, lower-cost, and superior-quality biologics. With over a decade of experience, the company has advanced life-saving medicines from research to patient care, focusing on unmet global biomedical and national biodefense needs. Its portfolio includes drugs for smallpox, Ebola, cancer, autoimmune, and infectious diseases.
JURA Bio is pioneering AI-native drug discovery by bridging the gap between computational design and physical reality in biological AI. Their mission is to revolutionize the discovery and development of safe and effective drugs, making even the hardest therapeutic targets tractable. By leveraging manufacturing-aware generative models, JURA Bio not only designs new therapeutics but also builds, tests, and learns from them at unprecedented scale. Their approach integrates machine learning, synthetic biology, and high-throughput experimentation to create a new paradigm in drug discovery, where AI learns from tens of billions of real protein interactions and every candidate is inherently human-safe.
The Wagar Lab at UC Irvine investigates the initiation, regulation, and resolution of human immune responses to infectious diseases and vaccines, with a focus on lymphoid and mucosal tissues. Their mission is to accelerate vaccine and immunotherapy design by understanding and manipulating the specialized immune microenvironments in human tissues. Using innovative immune organoid models, the lab aims to improve translational vaccine studies, enable novel mechanistic experiments, and explore genetic and environmental contributions to immune variation, particularly in the context of respiratory infections.
Macro Biologics, Inc. is dedicated to designing, patenting, and producing macro biologics, which are large molecule biologics with both physical properties and functional activities. These biologics are composed of natural building blocks, such as amino acids or carbohydrates, and are designed to degrade back into their natural components, making them environmentally friendly. The company aims to address significant global challenges, such as antibiotic resistance and pollution, by providing biologics that are safe for both people and the environment. Macro Biologics is committed to the highest standards of science, medicine, and business, with a focus on healthcare applications.
The University of Arizona Applied Research Corporation (UA-ARC) is a non-profit organization affiliated with the University of Arizona, dedicated to leveraging the university's strengths in research and education to address national security challenges. UA-ARC aims to deliver innovative solutions and foster collaborations between academia, industry, and government.
The University of Utah (UU) is a leading research institution recognized for its research activity and commitment to innovation and discovery. As an R1 Institution, it is dedicated to advancing knowledge and solving critical problems that challenge our national security interests and impact the global community. We foster interdisciplinary collaboration and provide resources to drive transformative research focused on enhancing medical care superiority for the U.S. Department of Defense (DoD) through advanced medical and engineering research sponsored by our Applied Medical & Engineering Laboratory (AM&E Lab). As a leading public university, UU also provides healthcare services to seven states in the Intermountain West, with the largest catchment of remote and austere frontier territory for any academic center. Leveraging its geographic advantage, technological and commercialization strengths, expertise in medical services, and leading-edge, core engineering competencies, UU is uniquely positioned to address the nation's critical national security interests.
LenioBio GmbH develops scalable eukaryotic cell-free protein expression technologies enabling rapid and flexible production of complex proteins. Its proprietary platform facilitates expression of membrane proteins, antibodies, virus-like particles, and proteins with complex post-translational modifications, supporting applications from research to biomanufacturing and vaccine development. The technology addresses key bottlenecks in traditional protein production, offering fast turnaround, batch consistency, and the potential for integration with rapid DNA template synthesis. LenioBio collaborates with leading industry partners and continually advances its platform for broad accessibility and application in life sciences.
The Institute for Biohealth Innovation (IBI) at George Mason University unites over 300 faculty and thousands of students across 34 departments to advance human health and well-being through innovative research. The IBI focuses on major health challenges, including infectious diseases, cancer, brain and behavior, and cardiovascular health, collaborating with national and international partners to implement solutions that enhance health outcomes.
The University of Minnesota's Research and Innovation Office (RIO) serves as a central resource for conducting, managing, and sponsoring research. It aims to facilitate collaborative research that addresses complex problems and promotes innovations that improve lives. RIO oversees research compliance and administration, fostering a culture of integrity and ethical practices in research. Additionally, RIO is committed to enhancing research capacity through various funding opportunities and strategic initiatives, including the management of specialized facilities for biocontainment research.
The University of Notre Dame, founded in 1842, is a prestigious Catholic research university located in South Bend, Indiana. It is dedicated to providing a holistic education that integrates faith, reason, and service to others. The university aims to be a leading global Catholic research institution, fostering a community of scholars committed to inquiry, justice, and the common good.
New York University (NYU) is a global university that connects talented and ambitious individuals in some of the world's greatest cities. Its mission is to be a top-quality institution, providing a diverse range of academic programs and opportunities for students to engage with the world's challenges. NYU is committed to fostering innovation and entrepreneurship, and it emphasizes diversity, equity, and inclusion in its educational mission. Founded in 1831, NYU has evolved to become a leader in higher education, with a commitment to accessibility and a diverse student body. NYU offers a wide array of academic programs, including accelerated studies and online education, catering to the needs of a global student population.
The Wyss Institute for Biologically Inspired Engineering uses biological design principles to develop new engineering innovations that will transform medicine and create a more sustainable world. At the Wyss Institute, we leverage recent insights into how Nature builds, controls and manufactures to develop new engineering innovations - a new field of research we call Biologically Inspired Engineering. By emulating biological principles of self assembly, organization and regulation, we are developing disruptive technology solutions for healthcare, energy, architecture, robotics, and manufacturing, which are translated into commercial products and therapies through formation of new startups and corporate alliances.
Northwestern University is a prestigious institution dedicated to fostering a diverse and inclusive environment, promoting academic excellence, and engaging in impactful research. With campuses in Evanston, Chicago, and Doha, Qatar, Northwestern emphasizes global engagement and community involvement, preparing students to tackle complex challenges through interdisciplinary collaboration and innovative thinking.
The University of Iowa is dedicated to providing a comprehensive educational experience that fosters academic excellence, research opportunities, and a vibrant student life. With a commitment to accessibility and inclusivity, the university aims to prepare its students for success in various fields while promoting a supportive community.
Case Western Reserve University is dedicated to solving the biggest issues of today and tomorrow through innovative research and education. With a commitment to experiential learning, the university offers a wide range of programs and opportunities for students to engage in research, internships, and community service, all within a vibrant campus located in Cleveland, Ohio.
The University of Alaska Fairbanks (UAF) is a Land, Sea, and Space Grant university and an international center for research, education, and the arts, emphasizing the circumpolar North and its diverse peoples. UAF integrates teaching, research, and public service as it educates students for active citizenship and prepares them for lifelong learning and careers.
New Jersey Institute of Technology (NJIT) is a leading public research university dedicated to providing students with a world-class education in STEM fields and beyond. With a commitment to academic excellence, NJIT prepares students to be leaders in the most in-demand fields through innovative programs, expert faculty, and extensive research opportunities. NJIT is recognized for its affordability and return on investment, making it a top choice for students seeking a quality education. NJIT is also ranked among the top public universities in the nation, known for its diverse student body and commitment to fostering an inclusive environment.
The University of Arkansas for Medical Sciences Office of Research and Sponsored Programs (ORSP) is dedicated to supporting UAMS faculty in acquiring, performing, and administering projects funded by external sources. The ORSP ensures compliance with policies, negotiates award terms, liaises between investigators and sponsors, and manages subcontracts.
Founded by Thomas Jefferson in 1819, the University of Virginia is a prestigious public university that emphasizes the advancement of human knowledge, education of leaders, and cultivation of an informed citizenry. It is recognized for its commitment to academic excellence, vibrant student life, and a strong alumni network, making it one of the top public universities in the United States.
The University of Missouri is dedicated to advancing research, innovation, and impact through a comprehensive support system for faculty, students, and staff. It aims to foster collaboration, enhance economic development, and promote entrepreneurship, while ensuring compliance with research regulations and ethical standards. The university also emphasizes the importance of interdisciplinary partnerships and provides resources to support veteran entrepreneurs through programs like the Entrepreneurship Bootcamp for Veterans.
Prolific Machines is pioneering the use of optogenetics and AI-driven bioprocess optimization to revolutionize biomanufacturing. Their mission is to illuminate biology’s limitless potential for a healthier tomorrow by enabling the production of next-generation therapeutics and broadening patient access to life-altering medicines. Founded in 2020, the company has developed a unique Photomolecular™ platform that uses light to precisely control cellular functions, boosting yields, improving quality, and enabling the manufacture of complex biotherapeutics. With a focus on strategic partnerships, Prolific Machines collaborates with innovators in biopharma and advanced nutrition, offering flexible, scalable solutions and in-house cell line development up to 200-liter pilot scale. The company is recognized for its commitment to safety, innovation, and a collaborative, diverse team culture.
The University of Massachusetts Lowell (UML) is dedicated to providing a comprehensive educational experience that prepares students for success in their careers and lives. With over 200 degree programs and a commitment to research and community engagement, UML fosters a vibrant learning environment for its diverse student body.
Aphios is a green biotechnology company focused on developing enabling nanotechnology platforms and enhanced therapeutics for health maintenance, disease prevention, and treatment of various conditions including cancers, infectious diseases, and central nervous system (CNS) disorders. The company emphasizes environmentally-sustainable practices and aims to improve the quality of life through innovative therapies.
The University of Nebraska Medical Center (UNMC) is dedicated to transforming lives through premier educational programs, innovative research, and extraordinary patient care. Founded in 1869, UNMC is a leader in health sciences education and research, serving as a vital resource for Nebraska and beyond.
The University of Georgia (UGA) is dedicated to facilitating instruction, scholarly and creative activity, and research collaborations across disciplines. UGA is a leader in research-based products and innovation, significantly impacting the state of Georgia and beyond through its extensive research initiatives and academic programs.
MassBiologics, part of UMass Chan Medical School, is the only nonprofit, FDA-licensed manufacturer of vaccines and biologics in the United States. With over 100 years of experience, it is dedicated to improving public health through the research, development, and production of biologic products, including vaccines and monoclonal antibodies.
The Medical University of South Carolina (MUSC) is South Carolina’s premier biomedical research institution, dedicated to advancing health through innovative research, education, and clinical care. With over $300 million in research funding and a commitment to addressing pressing health challenges, MUSC fosters collaboration among faculty, staff, and community partners to translate scientific discoveries into impactful health solutions. The South Carolina Clinical & Translational Research Institute (SCTR) at MUSC supports innovative research across the translational spectrum, from basic science to population health, including patient-centered and community-engaged research.
The UCI Office of Research is dedicated to supporting and enhancing the creative and scholarly activities of UCI faculty and researchers. It provides central administrative support for research programs, ensuring compliance with regulations and fostering an environment conducive to research and innovation.
Precision Antibody is a leading provider of custom antibody development services, with over 24 years of experience and more than 20,000 successful projects delivered to over 500 organizations worldwide. The company specializes in rapid, high-quality, application-specific monoclonal and polyclonal antibody development, production, and characterization, serving pharmaceutical, biotech, academic, and government clients. Precision Antibody is recognized for its proprietary technologies, award-winning services, and a success rate exceeding 95% in delivering antibodies that perform as intended. Accredited by AAALAC and OLAW, the company is committed to strict quality control, confidentiality, and milestone-based, transparent pricing. Their mission is to enable scientific advancement through innovative, reliable, and tailored antibody solutions.
The Clemson University Research Foundation (CURF) is dedicated to advancing the research enterprise at Clemson University by connecting faculty and students with industry partners. CURF facilitates the commercialization of university technologies, supports research collaboration, and promotes innovation through various funding and support programs.
Virginia Tech is a leading research institution dedicated to improving the quality of life and the human condition through education, research, and community engagement. With a commitment to its motto, 'Ut Prosim' (That I May Serve), Virginia Tech fosters a collaborative environment that integrates technology into all disciplines, preparing scholars to be leaders and problem-solvers.
LSU Health Sciences Center New Orleans is dedicated to educating future health professionals and scientists, advancing research, and providing exceptional healthcare. With six professional schools and numerous affiliated hospitals, LSUHSC-NO aims to improve health outcomes and address health equity challenges in Louisiana.
Northeastern University is a global research university founded in 1898, renowned for its experiential learning model, high-impact research, and deep partnerships. The university emphasizes innovative teaching and research that engage students, faculty, and alumni in solving real-world problems, fostering a dynamic and inclusive community across its 13 campuses worldwide.
The University of Montana (UM) is a flagship public research university located in Missoula, Montana. Established in 1893, UM offers a wide range of undergraduate and graduate programs, emphasizing research, creativity, and community engagement. With a commitment to academic excellence and public service, UM aims to transform lives through education and research, fostering a diverse and inclusive environment for its students.
The University at Buffalo is a leading public research university and flagship of the SUNY System, recognized for its innovative research and commitment to societal impact. It aims to transform scientific and technological breakthroughs into global impact, addressing complex challenges through interdisciplinary collaboration.
UC San Francisco is a leading university dedicated to advancing health worldwide through preeminent biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. With a commitment to public service, UCSF aims to innovate health care approaches for vulnerable populations and train the next generation of health professionals.
Vaxart is a clinical-stage biotechnology company focused on developing oral recombinant vaccines using a proprietary delivery platform. Their mission is to create transformative vaccines that are easier to distribute and administer, aiming to improve global public health by addressing common viral infections.
SUNY Upstate Medical University is a leading academic medical center in Central New York, dedicated to providing exceptional patient care, advancing medical research, and educating future healthcare professionals. As the region's only Level I trauma center and a Magnet recognized institution, Upstate is committed to delivering cutting-edge, life-saving treatments and fostering a compassionate, patient-centered environment. The university also plays a significant role in the community through outreach programs and is recognized as one of America's best large employers by Forbes.
Washington State University (WSU) is a public research university dedicated to improving lives by serving the public good. With a commitment to unlocking possibilities, WSU empowers students, faculty, and others to create a world where all people can thrive. The university offers a diverse range of academic programs across its six campuses and is recognized for its high research activity and community engagement.
UCLA is a leading public research university located in Los Angeles, California. It is renowned for its commitment to the creation, dissemination, preservation, and application of knowledge for the advancement of global society. With a rich history of academic and athletic excellence, UCLA offers a comprehensive environment that supports both academic and personal growth. The university is dedicated to fostering innovation and making a significant impact on the world through groundbreaking research and transformative practices.
Rx Bandz is dedicated to developing innovative, next-generation auto-injectors and life-saving formulations that provide simple solutions for patients, first responders, and the military. Their mission is to enhance the delivery of injectable medications, ensuring accessibility and ease of use for anyone, anytime, anywhere.
Arizona State University (ASU) is a comprehensive public research university known for its commitment to inclusivity, excellence, and societal impact. ASU is dedicated to advancing research-based solutions for global challenges, fostering strong leadership, and providing quality education accessible to all learners. The university is recognized for its innovative approach to education and its efforts in sustainability, research, and community service. ASU exemplifies a new prototype for the American public research university, focusing on excellence, broad access to quality education, and meaningful societal impact.
The Medical College of Wisconsin (MCW) is dedicated to transforming healthcare through innovative education, research, and patient care. With a focus on academic medicine, MCW aims to improve the health of communities by fostering a collaborative learning environment that integrates medical education with groundbreaking research and comprehensive patient care.
Indiana University is dedicated to building a better future through education, research, and community engagement. With a commitment to academic excellence, IU offers a diverse range of programs across its nine campuses, fostering an inclusive environment for over 90,000 students from around the world. IU is also at the forefront of groundbreaking research, particularly in areas such as brain health and Alzheimer's disease.
The University of Tennessee, Knoxville is dedicated to advancing knowledge and understanding through research, scholarship, and creative work. The Office of Research, Innovation, and Economic Development supports faculty, staff, and students in developing competitive proposals and fostering a strong culture of research integrity, aiming to create a more just, prosperous, and sustainable world.
Signature Science, LLC is a multidisciplinary applied science and technology company dedicated to solving the toughest forensic, biosecurity, and public health challenges. Serving both government and commercial clients, Signature Science combines scientific rigor with proven quality assurance to enhance the credibility and defensibility of programs in national security, public safety, and health security. The company is recognized for its innovation, technical excellence, and commitment to advancing the state-of-the-art in forensic science, genomics, and biosecurity technologies. Signature Science also offers advanced bioinformatics and microbiome analysis services, empowering clients with data-driven insights to address emerging threats, pandemics, and bioterrorism. The company is a subsidiary of Southwest Research Institute and is committed to community engagement and workforce development.
The Center for Military Medicine Research (CMMR) at the University of Pittsburgh is dedicated to advancing medical research for wounded service members and their families. The center focuses on trauma, emergency, and critical care, leveraging the university's strengths in medical and engineering fields, and collaborating with Carnegie Mellon University's robotics and AI expertise. CMMR aims to enhance trauma care for warfighters and civilians, contributing to the defense innovation economy.
The Texas A&M Engineering Experiment Station (TEES) is a state agency and part of the Texas A&M University System, dedicated to improving lives through engineering research, workforce development, and technology transition. TEES collaborates with industry, academia, and government to provide innovative solutions to global technical challenges.

Arizona State University
ASU Crosscutting Technologies to Enhance Military Medical Readiness and Resilience
Dr. Rachel Cassalia leads MTEC-supported efforts at ASU to shift military health from reactive care to proactive readiness through data-driven prevention.
University of Pittsburgh
Topical Metformin Lotion for Tendinopathy Prevention
University of Pittsburgh study shows topical metformin prevents overuse tendon injury. This work was sponsored through MTEC project 22-02-MPAI-014.
Theradaptive
Theradaptive’s RESTORE Trial Initiation for OsteoAdapt™ DE
Theradaptive launches RESTORE Phase I/II trial of OsteoAdapt™ DE for faster, precision bone healing in craniofacial injuries. MTEC-funded study targets improved recovery for military and civilian patients.
Altec
Autonomous Rehabilitation Device for Improved Recovery in Warfighters
The OSCIR platform—developed by Altec Inc in collaboration with the Naval Health Research Center—is bringing clinical-grade, real-time movement analysis to the front lines. Funded under MTEC-22-02-MPAI