FiteBac Pharma
FiteBac Technology/FiteBac Pharma's K21 uniquely targets the underlying disease state, given that most diseases involve microbial-associated inflammation and mitochondrial dysfunction. FiteBac Technology innovations stem from the work of numerous international academic research scientists. FiteBac Pharma K21 is the blockbuster antimicrobial small molecule designed to modulate biological, immunological, and metabolic systems for treating a wide range of infectious and inflammatory diseases. This patented drug substance has demonstrated the ability to safely eliminate bacterial, fungal, and viral infections, enhance innate immunity, induce mitophagy while improving mitochondrial and cellular metabolism, accelerate wound healing, and even promote the development of zebrafish and chickens, leading to increased adult mass. Rigorous research from Dr. Bhupesh Prusty's laboratory and Dr Christopher Rongo's laboratory is focused on various aspects of mitochondrial remodeling and reprograming, as well as mitochondrial-to-nuclear signaling with K21.
Industries
N/A
Nr. of Employees
small (1-50)
FiteBac Pharma is currently seeking investment
FiteBac Pharma is seeking a series-a investment in the range of 1m-5m
Products
Antimicrobial cavity cleanser (2% quaternary ammonium in aqueous ethanol)
Topical cavity cleansing solution formulated as a low‑migration quaternary ammonium silane in aqueous ethanol for disinfecting cavity preparations and reducing oral microbes prior to restoration.
Methacryloxy silicate antimicrobial additive for orthodontic acrylics
Methacryloxy silicate additive intended for copolymerization into MMA/PMMA orthodontic acrylics and removable dental appliances to provide contact‑killing antimicrobial properties and modify mechanical properties.
Antimicrobial glass, silica and nanoparticle filler products (product codes: G30, G41, G50, G55, RD70, S171, S1711)
Particulate antimicrobial glass, silica and nanoparticle silsesquioxane fillers offered in a range of formulations and particle sizes for integration into composites and resin systems; some variants specify refractive index and particle size.
K18 family antimicrobial monomer variants (K18, K18M, K18H, K18U, K18IBOA)
Series of antimicrobial monomer/oligomer variants formatted for use across adhesives, sealants, cements, endodontic sealers, orthodontic acrylics, dentures, 3D printing resins and other resin systems; technical datasheets available.
K21 antimicrobial formulation (product code K21) for rinses, sealants and cavity applications
Antimicrobial formulation offered for use in cavity cleansers, mouth rinses and sealant formulations; related antifungal and antiviral activity has been reported in technical posters and reports.
Antimicrobial cavity cleanser (2% quaternary ammonium in aqueous ethanol)
Topical cavity cleansing solution formulated as a low‑migration quaternary ammonium silane in aqueous ethanol for disinfecting cavity preparations and reducing oral microbes prior to restoration.
Methacryloxy silicate antimicrobial additive for orthodontic acrylics
Methacryloxy silicate additive intended for copolymerization into MMA/PMMA orthodontic acrylics and removable dental appliances to provide contact‑killing antimicrobial properties and modify mechanical properties.
Antimicrobial glass, silica and nanoparticle filler products (product codes: G30, G41, G50, G55, RD70, S171, S1711)
Particulate antimicrobial glass, silica and nanoparticle silsesquioxane fillers offered in a range of formulations and particle sizes for integration into composites and resin systems; some variants specify refractive index and particle size.
K18 family antimicrobial monomer variants (K18, K18M, K18H, K18U, K18IBOA)
Series of antimicrobial monomer/oligomer variants formatted for use across adhesives, sealants, cements, endodontic sealers, orthodontic acrylics, dentures, 3D printing resins and other resin systems; technical datasheets available.
K21 antimicrobial formulation (product code K21) for rinses, sealants and cavity applications
Antimicrobial formulation offered for use in cavity cleansers, mouth rinses and sealant formulations; related antifungal and antiviral activity has been reported in technical posters and reports.
Expertise Areas
- Antimicrobial materials development
- Dental restorative and appliance material chemistry
- Polymer additive formulation and masterbatch integration
- Surface modification for adhesion and bondability
Key Technologies
- Quaternary ammonium silane chemistries
- Trialkoxysilane / TEOS anchoring chemistry
- Sol‑gel and ORMOSIL processing
- Silsesquioxane nanoparticle production
Key People
News & Updates
Research article detailing the mechanism by which quaternary ammonium silane compounds disrupt bacterial membranes and biofilms.
Clinical trial evaluating the antimicrobial efficacy of QAMS-containing orthodontic acrylic resin in vivo.
Study on the antiviral properties of K21 against herpes viruses.
Study demonstrating the antifungal efficacy of K21 against fluconazole-resistant Candida species.
Anti-viral Activity of Quaternary Ammonium Silane (K21) Against HHV-6A and HHV-7
The antiviral compound K21, a quaternary ammonium silane, demonstrates significant inhibitory effects against HHV-6A and HHV-7 in vitro. While also showing some activity against HSV-1, K21 is considerably more potent against HHV-6A and HHV-7. This suggests a potential role for K21 in treating infections caused by these viruses
Study showing that K21 inhibits replication of a broad range of viruses, including both enveloped and non-enveloped DNA and RNA viruses.K21 has been shown to inhibit the replication of a wide range of viruses, including both enveloped viruses (like HSV-1, HHV-6, HHV-7, and influenza A) and non-enveloped viruses (like phage MS2 and feline norovirus)
Research article detailing the mechanism by which quaternary ammonium silane compounds disrupt bacterial membranes and biofilms.
Clinical trial evaluating the antimicrobial efficacy of QAMS-containing orthodontic acrylic resin in vivo.
Study on the antiviral properties of K21 against herpes viruses.
Study demonstrating the antifungal efficacy of K21 against fluconazole-resistant Candida species.
Anti-viral Activity of Quaternary Ammonium Silane (K21) Against HHV-6A and HHV-7
The antiviral compound K21, a quaternary ammonium silane, demonstrates significant inhibitory effects against HHV-6A and HHV-7 in vitro. While also showing some activity against HSV-1, K21 is considerably more potent against HHV-6A and HHV-7. This suggests a potential role for K21 in treating infections caused by these viruses
Study showing that K21 inhibits replication of a broad range of viruses, including both enveloped and non-enveloped DNA and RNA viruses.K21 has been shown to inhibit the replication of a wide range of viruses, including both enveloped viruses (like HSV-1, HHV-6, HHV-7, and influenza A) and non-enveloped viruses (like phage MS2 and feline norovirus)