Chemical, Nuclear, Radiation Defense

This capability integrates fast, field-deployable detection, biodosimetry, decontamination, antidotes and supportive care pathways for CBRN (chemical, biological, radiological, nuclear) exposures. It emphasizes durable countermeasures, decision support, and systems that function in austere, prolonged-care and delayed-evacuation environments.

Technical Challenges

  • Rapid, accurate point-of-care detection and quantification of low-dose radiation and mixed chemical exposures in noisy operational environments.

  • Real-time biodosimetry and prognostic tools to stratify casualties for evacuation, decorporation, or prolonged field care.

  • Effective, field-suitable decontamination and containment methods that are non-damaging to tissues and equipment.

  • Stable, easy-to-administer medical countermeasures (antidotes, chelators, radioprotectors) with minimal logistical burden.

Emerging Opportunities

  • Portable, validated biodosimeters and biomarkers that predict delayed radiation syndromes and combined-injury outcomes.

  • Integrated clinical decision-support linking sensor data, exposure history, and triage algorithms for medics under fire.

  • Shelf-stable, broad-spectrum countermeasures that cover organophosphates, vesicants, radioactive isotopes, and internal contamination.

  • Validated decontamination solutions and PPE optimized for prolonged use in hot, austere, or resource-limited settings.

Current and Emerging Technologies in Chemical, Nuclear, Radiation Defense

Field-deployable detection and sensor networks

Miniaturized mass spectrometers, electrochemical sensors, and multiplexed biosensors for rapid identification of toxic agents and radionuclides at point-of-contact.

Biodosimetry and biomarker platforms

Genomic, proteomic, and metabolomic assays and portable immunoassays to estimate absorbed dose, predict hematopoietic failure, and guide decorporation therapy.

Advanced decontamination and PPE

Novel adsorbents, enzymatic neutralizers, and wearable, breathable protective fabrics that reduce dermal absorption while enabling prolonged operations.

Pharmacologic countermeasures and decorporation agents

Next-generation antidotes, chelators, and radio-protectors formulated for intramuscular, intranasal, or auto-injector delivery and extended shelf-life.

Wearables, telemedicine, and decision-support AI

Physiologic monitoring, exposure logging, and AI-driven triage tools to prioritize care, predict deterioration, and guide prolonged field management.

Radiation mitigation and regenerative therapies

Cell- and cytokine-based approaches to accelerate hematopoietic recovery, mitigate fibrosis, and treat combined blast-plus-radiation polytrauma.

Importance to Military Medicine

Improves combat casualty outcomes

Early detection and targeted therapies reduce mortality from chemical and radiation injuries and limit progression to multi-organ failure in polytrauma.

Enables prolonged and distributed care

Portable diagnostics, robust countermeasures, and telehealth preserve force health during delayed evacuation and austere operations.

Maintains readiness and force protection

Rapid surveillance and mitigation strategies limit mission degradation from CBRN incidents and support resilient unit-level operations.

Supports civilian surge and dual-use resilience

Technologies developed for military deployment translate to civilian emergency response, mass-casualty care, and public health preparedness.

Alignment with the MTEC Mission

Directly advances MTEC mission by accelerating translational development of medical countermeasures and field-ready diagnostics for Warfighters.

Fosters multi-sector collaboration among DoD, industry, and academia to de-risk technologies and shorten timelines from concept to deployment.

Prioritizes dual-use outcomes, ensuring civilian benefit and surge-capacity solutions align with DoD readiness requirements.

Supports MTEC’s portfolio approach—integrating CBRN defense with trauma, prolonged care, and performance medicine for comprehensive force health solutions.

Dual-Use (Military + Civilian) Applications

Civilian emergency medicine: rapid diagnostics and countermeasures scale to mass-casualty incidents, industrial chemical spills, and radiologic events.

Public health and hospital surge capacity: biodosimetry and triage tools support allocation of limited resources during large-scale exposures.

Industrial and environmental monitoring: sensor networks and neutralizers reduce routine occupational risks and civilian contamination events.

Clinical research and regenerative therapies: lessons from military-grade radiomitigation inform civilian oncology supportive care and radiation injury recovery.

Explore MTEC Members with Chemical, Nuclear, Radiation Defense Capabilities

MTEC members bring cross-disciplinary strengths—medical device firms, biotech developers, academic translational research centers, and clinical networks—to accelerate validation, regulatory pathways, and field evaluation.

Members contribute unique access to DoD priorities, clinical trial expertise, manufacturing scale-up, and dual-use commercialization channels.

Explore MTEC member profiles to identify partners with capabilities in biodosimetry, decontamination chemistry, countermeasure formulation, wearable sensors, and prolonged-field-care systems.

85 Members with Chemical, Nuclear, Radiation Defense capabilities.

Member
Georgia Southern University

Georgia Southern University is a vibrant institution with over 26,100 students across three campuses in Statesboro, Savannah, and Hinesville. The university offers 132 degree programs at the associate, bachelor’s, master’s, and doctorate levels, emphasizing student success, community impact, and research excellence. With a commitment to inclusivity and engagement, Georgia Southern fosters a supportive environment for diverse learners, including military-affiliated and adult students. The university is dedicated to transforming lives through education and community engagement, aligning its programs with regional needs. Additionally, Georgia Southern provides accelerated pathways for students to fast-track their master's degrees, enhancing educational opportunities. The university also emphasizes career readiness and public impact research, preparing students for successful careers and contributing to community development.

Member
FiteBac Pharma

FiteBac Technology/FiteBac Pharma's K21 uniquely targets the underlying disease state, given that most diseases involve microbial-associated inflammation and mitochondrial dysfunction. FiteBac Technology innovations stem from the work of numerous international academic research scientists. FiteBac Pharma K21 is the blockbuster antimicrobial small molecule designed to modulate biological, immunological, and metabolic systems for treating a wide range of infectious and inflammatory diseases. This patented drug substance has demonstrated the ability to safely eliminate bacterial, fungal, and viral infections, enhance innate immunity, induce mitophagy while improving mitochondrial and cellular metabolism, accelerate wound healing, and even promote the development of zebrafish and chickens, leading to increased adult mass. Rigorous research from Dr. Bhupesh Prusty's laboratory and Dr Christopher Rongo's laboratory is focused on various aspects of mitochondrial remodeling and reprograming, as well as mitochondrial-to-nuclear signaling with K21.

Member
Humanetics Corporation

Humanetics Corporation is a clinical-stage pharmaceutical company based in Minneapolis, Minnesota, focused on developing and commercializing products to enhance human health and wellbeing. Founded in 1988, the company specializes in radiation modulators, adjunctive oncology therapies, and pulmonary protective therapies, particularly for COVID-19. Humanetics is known for its lead drug candidate, BIO 300, which is being developed as a radioprotectant for military and civilian use, as well as a treatment to improve outcomes in cancer patients receiving radiotherapy. The company is actively engaged in research programs for non-small cell lung cancer, prostate cancer, and head and neck cancers.

Member
Physical Sciences Inc.

Physical Sciences Inc. (PSI) is an employee-owned company dedicated to inventing, demonstrating, and translating technologies that address critical national needs in defense, security, healthcare, and environmental stewardship. With over 50 years of experience, PSI combines extensive research and development capabilities with a commitment to innovation and customer focus.

Member
Maverick Labs, Inc.

Maverick Labs is a U.S.-based biotechnology and materials science company specializing in advanced protein design, synthetic biology, and microbial engineering. The company operates through three tightly integrated subsidiaries—Maverick Metals, Maverick Energy, and the Maverick Bio-Gene Therapy Translational Unit—each of which applies a shared technological foundation to tackle critical challenges across national defense, energy independence, and strategic material access. Together, they develop scalable, field-ready solutions that reinforce the United States’ industrial resilience and military readiness through biotechnology-driven innovation.

Member
The University of Texas at San Antonio

The University of Texas at San Antonio (UTSA) is dedicated to the advancement of knowledge through research, teaching, and community engagement. As a premier public research university, UTSA embraces multicultural traditions and serves as a catalyst for socioeconomic development, providing access to educational excellence and preparing citizen leaders for the global environment.

Member
Auburn University

Auburn University Research & Economic Development is dedicated to advancing research and economic growth through a collaborative effort among its various colleges and departments. The organization focuses on fostering innovation, supporting faculty and student research, and facilitating partnerships with industry and government to address societal challenges and enhance the quality of life. Recent initiatives include the launch of the Team Science Series to promote interdisciplinary collaboration and the development of the Gulf Coast Engineering Research Station to address coastal environmental challenges.

Member
SERDA Therapeutics

SERDA Therapeutics is a clinical stage biopharmaceutical company focused on developing innovative solutions for wound care, particularly in the treatment of burn injuries and chronic ulcers. The company aims to provide fast and effective therapeutic debridement through its proprietary enzymatic product, SN514, which is designed to enhance healing by selectively removing necrotic tissue.

Member
University of Arkansas

The Institute for Integrative & Innovative Research (I3R) at the University of Arkansas is dedicated to pioneering solutions to complex societal challenges through convergence research. With a mission to advance research excellence and stimulate economic development, I3R focuses on deploying innovations at scale through collaboration across various sectors, including academia, industry, and government.

Member
The University of Texas Medical Branch at Galveston

UTMB is dedicated to supporting research, education, and scholarly endeavors, with a focus on creating the future of healthcare through innovative research and community engagement.

Member
HELM Innovations

HELM Innovations is a service-disabled veteran-owned small business specializing in the integration of science, technology, and programmatic and strategic solutions, primarily for U.S. federal government clients. With over 30 years of experience in national security, systems engineering, and interagency collaboration, the company provides expertise in areas such as complex systems acquisition, R&D, environmental lab testing, crisis response, and leadership development. HELM Innovations is noted for applying advanced business models, fostering cross-disciplinary teamwork, and supporting rapid, effective decision-making in complex environments.

Member
The University of Chicago

The University of Chicago is a prestigious urban research university committed to rigorous inquiry and intellectual freedom. Founded in 1890, it has produced numerous Nobel laureates and is known for its transformative education and groundbreaking research across various fields. The university fosters an inclusive and diverse learning environment, encouraging participation from all community members.

Member
Booz Allen Hamilton

Booz Allen Hamilton is a leading management and technology consulting firm with over 110 years of experience. The company is dedicated to empowering people to change the world through innovative solutions in various sectors including cybersecurity, artificial intelligence, engineering, and defense. Booz Allen partners with government and commercial clients to tackle their most complex challenges, leveraging a culture of innovation and a commitment to excellence. The firm operates with core values of integrity, courage, service, ingenuity, and a commitment to diversity and inclusion.

Member
Baylor University

Baylor University is a preeminent Christian research university committed to addressing the world's most meaningful challenges through top-tier research and scholarship. Recognized as an R1 research institution, Baylor focuses on infusing its distinct Christian mission into its research initiatives, fostering a commitment to excellence and innovation.

Member
Exponent

Exponent is a multidisciplinary science and engineering consulting firm serving sectors including healthcare, energy, manufacturing, and consumer products. From medical devices, pharmaceuticals, and supplements to digital health and wearables, we deliver rigorous science that quantifies impacts on human health. Exponent helps you push the envelope on the development, deployment, safety, and effectiveness of cutting-edge drugs, devices, and diagnostics — concomitantly balancing benefits and risks. Count on our multidisciplinary, data-driven, evidence-based assessments to give you clarity on your most complex product needs and challenges. With lives on the line, innovations that support healthcare demand the highest levels of scientific rigor. Whether you’re developing a novel drug, a sturdier stent, or a faster flu test, you need clear answers to complex questions, quickly. Exponent supports our life sciences clients across the total product lifecycle by solving critical design, regulatory, safety, and market access challenges. We can collaborate with you throughout your journey, helping you navigate risks and opportunities — and optimize outcomes — with science-based strategies and specialized expertise.

Member
University of Cincinnati Office of Research

The University of Cincinnati Office of Research is a premier R1 urban research institution dedicated to advancing transformative knowledge and disruptive discoveries that address real-world challenges. Guided by its Research2030 strategic plan, the Office fosters interdisciplinary collaboration, supports innovative research initiatives, and connects industry, government, and community partners with UC's thought leaders. The Office accelerates economic growth and societal impact by investing in key research strengths such as analytics, cyber, robotics, sensors, skin science, adolescence, cancer, digital humanities, infectious diseases, medical devices, neuroscience, smart cities, sustainability, urban futures, and water. With a strong commitment to transparency, compliance, and research security, the Office provides comprehensive support for faculty, students, and staff throughout the research lifecycle, ensuring excellence and integrity in all scholarly activities. Specialized programs and support offices include biosafety, animal care, research integrity, cybersecurity, human research protection, defense research initiatives, government cost compliance, and radiation safety, all designed to uphold the highest standards of ethical, safe, and innovative research. The Office also keeps the community informed and engaged through its monthly 'Findings' newsletter, highlighting impactful research, partnerships, and opportunities.

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Projects

Technology Showcase

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Non-Invasive Glymphatic (GF) Monitoring and Recovery Optimization for Warfighter Cognitive Readiness

Applied Cognition is developing non-invasive glymphatic monitoring and recovery technologies to enhance warfighter cognitive readiness, resilience, and sleep recovery.

Moberg Analytics

Moberg Analytics – Advanced Brain Monitoring & Critical Care Informatic

Moberg’s platform unifies brain monitoring data for faster, precise treatment of severe brain injuries in military and civilian care.

University of California San Francisco

TemPredict: AI-Driven Wearable Monitoring for Early Illness Detection and Warfighter Readiness

TemPredict: AI wearables detect early illness and health risks to support warfighter readiness.

Arizona State University

ASU Crosscutting Technologies to Enhance Military Medical Readiness and Resilience

Dr. Rachel Cassalia leads MTEC-supported efforts at ASU to shift military health from reactive care to proactive readiness through data-driven prevention.

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