CMTx Biotech, Inc.
CMTx Biotech, Inc. is an emerging biopharmaceutical company working to develop and commercialize host-directed therapeutics for the treatment of inflammatory and infectious diseases, as well as threat-agnostic medical countermeasures against high-priority chemical, biological, radiological and nuclear (CBRN) threats to homeland security and national defense. Our lead drug candidate is a clinically-tested, highly-stable, orally-administered small molecule that has been shown to improve survival and prevent lung injury in a wide variety of animal models of sepsis, acute respiratory distress syndrome (ARDS) and multiple organ dysfunction syndrome (MODS) across several species, including mice, rats, hamsters, pigs and sheep. Having already secured approximately $4M in funding to-date, including $3.6M in NIH SBIR/STTR grants, we are actively seeking non-dilutive funding, private investment capital and/or an established strategic partner to help advance human clinical trials and FDA Animal Rule development, as well as to expand our product pipeline.
Industries
Nr. of Employees
small (1-50)
CMTx Biotech, Inc.
Long Island High Technology Incubator (LIHTI), 25 Health Sciences Drive, Suite 314, Stony Brook, NY 11790-3350
CMTx Biotech, Inc. is currently seeking investment
CMTx Biotech, Inc. is seeking a seed investment in the range of 1m-5m
Products
Chemically modified tetracycline derivative (lead small-molecule candidate)
A non-antimicrobial, chemically modified tetracycline-class small-molecule candidate developed as an anti-inflammatory and MMP-inhibiting therapeutic for indications including acute lung injury, ARDS, sepsis complications, and potential pandemic respiratory disease treatment.
Chemically modified tetracycline derivative (lead small-molecule candidate)
A non-antimicrobial, chemically modified tetracycline-class small-molecule candidate developed as an anti-inflammatory and MMP-inhibiting therapeutic for indications including acute lung injury, ARDS, sepsis complications, and potential pandemic respiratory disease treatment.
Expertise Areas
- Clinical trial management (Phase I/II)
- Preclinical models of ARDS and sepsis
- Small-molecule therapeutic development
- Drug repurposing and computational screening
Key Technologies
- In silico drug repurposing / computational network analysis
- Clinically relevant animal models for lung injury and sepsis
- Matrix metalloproteinase (MMP) inhibition assays
- Cytokine and biomarker assays