Member

CMTx Biotech, Inc.


CMTx Biotech, Inc. is an emerging biopharmaceutical company working to develop and commercialize host-directed therapeutics for the treatment of inflammatory and infectious diseases, as well as threat-agnostic medical countermeasures against high-priority chemical, biological, radiological and nuclear (CBRN) threats to homeland security and national defense. Our lead drug candidate is a clinically-tested, highly-stable, orally-administered small molecule that has been shown to improve survival and prevent lung injury in a wide variety of animal models of sepsis, acute respiratory distress syndrome (ARDS) and multiple organ dysfunction syndrome (MODS) across several species, including mice, rats, hamsters, pigs and sheep. Having already secured approximately $4M in funding to-date, including $3.6M in NIH SBIR/STTR grants, we are actively seeking non-dilutive funding, private investment capital and/or an established strategic partner to help advance human clinical trials and FDA Animal Rule development, as well as to expand our product pipeline.

Industries

biotechnology
medical
pharmaceutical

Nr. of Employees

small (1-50)

CMTx Biotech, Inc.

Long Island High Technology Incubator (LIHTI), 25 Health Sciences Drive, Suite 314, Stony Brook, NY 11790-3350

CMTx Biotech, Inc. is currently seeking investment

CMTx Biotech, Inc. is seeking a seed investment in the range of 1m-5m

All Investment-seeking Members

Products

Chemically modified tetracycline derivative (lead small-molecule candidate)

A non-antimicrobial, chemically modified tetracycline-class small-molecule candidate developed as an anti-inflammatory and MMP-inhibiting therapeutic for indications including acute lung injury, ARDS, sepsis complications, and potential pandemic respiratory disease treatment.

Expertise Areas

  • Clinical trial management (Phase I/II)
  • Preclinical models of ARDS and sepsis
  • Small-molecule therapeutic development
  • Drug repurposing and computational screening
  • Show More (4)

Key Technologies

  • In silico drug repurposing / computational network analysis
  • Clinically relevant animal models for lung injury and sepsis
  • Matrix metalloproteinase (MMP) inhibition assays
  • Cytokine and biomarker assays
  • Show More (4)

Key People

Joseph Scaduto, MS, MBA

Co-Founder & Chief Executive Officer

LinkedIn

Lorne Golub, DMD, MSc, MD (Honorary)

Scientific Co-Founder

LinkedIn

James Keane, BS, MBA

Co-Founder and COO

LinkedIn

JoAnn Wilson, PhD

Chemistry, Manufacturing and Controls

LinkedIn

Janet S Lee, PhD

Clinical Research

LinkedIn

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