Armed Forces Institute of Regenerative Medicine (AFIRM)
The Armed Forces Institute of Regenerative Medicine (AFIRM) , led by the Wake Forest Institute for Regenerative Medicine, is a collaborative effort involving over 30 academic institutions and industry partners. The consortium focuses on advancing regenerative medicine solutions for battlefield injuries, aiming to improve the lives of wounded service members, veterans, and the general public. With a $40 million, five-year award from the Defense Health Agency, AFIRM is dedicated to developing clinical therapies in areas such as craniofacial regeneration, extremity regeneration, genitourinary/lower abdomen, skin and wound healing, on-demand blood, and cellular therapies for trauma.
Armed Forces Institute of Regenerative Medicine (AFIRM)
What We Do
An innovative platform using functionalized acellular muscle fiber fragments to restore normal muscle mass and function, particularly for pelvic and urogenital injuries.
A biological product aimed at accelerating wound healing and preventing scarring in burn wounds, particularly in remote, pre-hospital settings.
A project focused on creating bioengineered constructs for repairing craniofacial and dental defects, enhancing functional and aesthetic recovery.
An injection therapy platform using decellularized muscle fiber fragments to improve muscle mass and function in rotator cuff injuries.
A cellular therapy aimed at enhancing prosthetic use by converting skin at the stump site to volar type, improving comfort and durability.
A synthetic platelet surrogate developed to enhance hemostatic function in traumatic brain injury-associated coagulopathy.
Application Area
Show More (7)Battlefield Resuscitation
Show More (1)Psychological and Cognitive Health and Performance
Biologics
Digital Health Technologies
Key People
Co-director for AFIRM and Professor of Bioengineering at the University of Pittsburgh
Lead Investigator for AFIRM and Director of the Wake Forest Institute for Regenerative Medicine