Hemorrhage Detection and Management

Rapid, objective detection and targeted management of bleeding integrates physiologic monitoring, point-of-injury diagnostics, and minimally invasive interventions to stop hemorrhage, preserve perfusion, and guide evacuation decisions in combat, prolonged field care, and austere civilian settings.

Technical Challenges

  • Rapid, noninvasive identification of internal and junctional hemorrhage before hemodynamic collapse

  • Robust, low-power sensors and algorithms that function in motion, extreme temperatures, and electromagnetic interference

  • Integration of hemorrhage detection with decision-support and communication during delayed or prolonged evacuation

  • Real-time assessment of efficacy of control measures (tourniquet, hemostatic agents, REBOA) at point of injury

Emerging Opportunities

  • Compact, wearable sensors that reliably detect occult bleeding and quantify volume/rate of blood loss

  • Automated triage tools that combine physiologic data, injury pattern, and limited diagnostics for non-expert providers

  • Field-deployable diagnostics to differentiate surgical bleeding from coagulopathy, anticoagulant effect, or trauma-induced coagulopathy

  • Validated algorithms and regulatory pathways for AI-assisted hemorrhage detection in austere and prehospital environments

Current and Emerging Technologies in Hemorrhage Detection and Management

Wearable and patch-based sensors

Photoplethysmography, impedance, and multi-modal biosensors that continuously monitor perfusion, hemoglobin trends, and compensatory physiology for early detection of bleeding.

Portable ultrasound and automated image interpretation

Compact FAST scanners with AI-assisted detection of free fluid and focused assessments to identify intrathoracic and intra-abdominal hemorrhage at point of care.

Blood loss quantification and wearable coagulation monitors

Near-patient assays and microfluidic platforms that rapidly assess platelet function, fibrinogen, and anticoagulant levels to guide targeted hemostatic therapy.

Automated decision-support and telemedicine links

Embedded clinical algorithms and secure comms that prioritize interventions, recommend hemostatic adjuncts (tourniquet, tranexamic acid, REBOA), and connect far-forward medics with specialists.

Advanced hemostatic devices and adjuncts

Biomaterial-based sealants, inflatable junctional devices, portable REBOA-compatible tools, and smart tourniquets that enable rapid, durable hemorrhage control in austere settings.

Importance to Military Medicine

Reduce preventable deaths

Hemorrhage remains the leading cause of potentially preventable death in combat; early detection and control directly improve survival.

Enable prolonged and distributed care

Technologies that identify and manage bleeding extend life-saving care when evacuation is delayed or environments are austere.

Improve readiness and force health protection

Rapid diagnostics and actionable guidance reduce morbidity, speed return-to-duty, and preserve unit capability.

Optimize resource use in mass-casualty events

Automated triage and monitoring help prioritize limited blood products, surgical assets, and evacuation assets during complex incidents.

Alignment with the MTEC Mission

Directly aligns with MTEC’s focus on accelerating medically relevant technologies from concept to fielded capability for Warfighters.

Supports MTEC portfolios in combat casualty care, prolonged and distributed care, and trauma diagnostics by translating innovations into operational solutions.

Enables dual-use impact—improving military readiness while offering civilian benefits for prehospital and hospital hemorrhage management.

Creates opportunities for multi-disciplinary consortia, rapid prototyping, and clinical validation consistent with MTEC’s mission to accelerate adoption.

Dual-Use (Military + Civilian) Applications

Civilian trauma care: faster triage in ambulances, EDs, and mass-casualty incidents reduces time to definitive control.

Prehospital emergency medical services: wearable detection and tele-guidance improve lay rescuer and medic performance.

Rural and austere healthcare: technologies developed for the battlefield translate to prolonged field care in remote civilian settings.

Hospital operations: rapid diagnostics for coagulopathy improve blood product stewardship and surgical planning.

Explore MTEC Members with Hemorrhage Detection and Management Capabilities

MTEC members bring clinical expertise, engineering capability, regulatory experience, and DoD operational insight to advance hemorrhage detection and management from prototype to deployment.

Through collaborative consortia, members accelerate validation studies, create operational testbeds, and address military-specific requirements such as low SWaP, ruggedization, and secure communications.

Explore member profiles to find partners with experience in biosensing, trauma surgery, materials science, AI diagnostics, and clinical trial execution to drive field-ready solutions.

103 Members with Hemorrhage Detection and Management capabilities.

Member
SIMETRI

SIMETRI is a woman-and-minority owned small business based in Winter Park, Florida, specializing in modeling, simulation, and training technologies. Founded in 2009, the company focuses on delivering innovative products and services that enhance the human experience and improve client outcomes through advanced training and program management analysis.

Member
Georgia Southern University

Georgia Southern University is a vibrant institution with over 26,100 students across three campuses in Statesboro, Savannah, and Hinesville. The university offers 132 degree programs at the associate, bachelor’s, master’s, and doctorate levels, emphasizing student success, community impact, and research excellence. With a commitment to inclusivity and engagement, Georgia Southern fosters a supportive environment for diverse learners, including military-affiliated and adult students. The university is dedicated to transforming lives through education and community engagement, aligning its programs with regional needs. Additionally, Georgia Southern provides accelerated pathways for students to fast-track their master's degrees, enhancing educational opportunities. The university also emphasizes career readiness and public impact research, preparing students for successful careers and contributing to community development.

Member
Teleflex

Teleflex is a global provider of medical technologies designed to improve the health and quality of people's lives. The company focuses on purpose-driven innovation to empower healthcare professionals and enhance patient outcomes across various medical fields.

Member
VirTech Bio

VirTech Bio is an early-stage biotechnology company based in Natick, Massachusetts, focused on developing a human-derived hemoglobin-based oxygen carrier (HBOC) for use as a temporary blood substitute in trauma and transplantation. The company leverages expertise in hemoglobin polymerization to address critical needs in emergency medicine and organ preservation, with a pipeline also targeting veterinary and research applications. Process innovations allow scalable and contract-based manufacturing, supported by significant non-dilutive funding from the US Department of Defense and private investment.

Member
Auburn University

Auburn University Research & Economic Development is dedicated to advancing research and economic growth through a collaborative effort among its various colleges and departments. The organization focuses on fostering innovation, supporting faculty and student research, and facilitating partnerships with industry and government to address societal challenges and enhance the quality of life. Recent initiatives include the launch of the Team Science Series to promote interdisciplinary collaboration and the development of the Gulf Coast Engineering Research Station to address coastal environmental challenges.

Member
University of Arkansas

The Institute for Integrative & Innovative Research (I3R) at the University of Arkansas is dedicated to pioneering solutions to complex societal challenges through convergence research. With a mission to advance research excellence and stimulate economic development, I3R focuses on deploying innovations at scale through collaboration across various sectors, including academia, industry, and government.

Member
The University of Chicago

The University of Chicago is a prestigious urban research university committed to rigorous inquiry and intellectual freedom. Founded in 1890, it has produced numerous Nobel laureates and is known for its transformative education and groundbreaking research across various fields. The university fosters an inclusive and diverse learning environment, encouraging participation from all community members.

Member
PinMed, Inc.

PinMed, Inc., is a National Innovation Award-winning bioinformatics/medical-device company that develops high-fidelity cardiovascular monitoring systems, personalized (adaptive) software, and integrated systems and custom solutions for tracking cardiovascular data in the most challenging environments (e.g., intensive activity, extreme electromagnetic interference, and interventional cardiovascular procedures) and identifying subtle but clinically important indicators of cardiovascular events. PinMed’s award-winning solutions include versatile, multisensor, high-fidelity monitoring systems for various hospital and ambulatory settings. The company has extensive experience in electronic and mechanical engineering, development of software and firmware for various processors, computational modeling, and cardiovascular physiology. PinMed’s flagship mobile platform, PELEX, provides unparalleled versatility in physiological monitoring and has been cleared by the FDA for diagnostic 12-lead ECG testing and various types of ambulatory monitoring.

Member
Boston University

Boston University is a major research institution committed to leading breakthroughs across various disciplines. The Office of Research supports and advances research excellence, fostering collaboration among researchers, industry partners, and government leaders to address significant societal challenges.

Member
Cooper University Health Care

Cooper University Health Care is a regional academic health system recognized for comprehensive clinical services, advanced multidisciplinary care, specialized surgery, and robust research in South Jersey. It provides integrated healthcare across general and specialty domains, including cancer, neurosciences, cardiology, trauma, genetics, addiction medicine, and complex surgical procedures, supported by leading technologies and a network of modern facilities.

Member
Baylor University

Baylor University is a preeminent Christian research university committed to addressing the world's most meaningful challenges through top-tier research and scholarship. Recognized as an R1 research institution, Baylor focuses on infusing its distinct Christian mission into its research initiatives, fostering a commitment to excellence and innovation.

Member
Vivosang Inc

Vivosang Inc is an investigational stage biotechnology company focused on developing pegylated human hemoglobin products to enhance oxygen delivery in medical applications, particularly in traumatic hemorrhagic injuries. Their lead product, VS-101, aims to provide targeted oxygen delivery to tissues in need, addressing significant medical needs in emergency and surgical settings.

Member
Exponent

Exponent is a multidisciplinary science and engineering consulting firm serving sectors including healthcare, energy, manufacturing, and consumer products. From medical devices, pharmaceuticals, and supplements to digital health and wearables, we deliver rigorous science that quantifies impacts on human health. Exponent helps you push the envelope on the development, deployment, safety, and effectiveness of cutting-edge drugs, devices, and diagnostics — concomitantly balancing benefits and risks. Count on our multidisciplinary, data-driven, evidence-based assessments to give you clarity on your most complex product needs and challenges. With lives on the line, innovations that support healthcare demand the highest levels of scientific rigor. Whether you’re developing a novel drug, a sturdier stent, or a faster flu test, you need clear answers to complex questions, quickly. Exponent supports our life sciences clients across the total product lifecycle by solving critical design, regulatory, safety, and market access challenges. We can collaborate with you throughout your journey, helping you navigate risks and opportunities — and optimize outcomes — with science-based strategies and specialized expertise.

Member
Thornhill Medical

Thornhill Medical specializes in advanced medical technologies for critical care, anesthesia, respiratory therapy, and vascular diagnostics. Their core offerings address clinical needs in austere, emergency, battlefield, and transport environments, enabling mobile and integrated life support, portable anesthesia, and precise non-invasive control and measurement of blood gases. With significant expertise in both product engineering and translational clinical research, the company supports deployments worldwide, collaborates with military and civilian partners, and contributes to innovation in healthcare delivery and device interoperability.

Member
Martin, Blanck & Associates, LLC

Martin, Blanck & Associates, LLC (MBA) is a healthcare consulting firm based in Alexandria, Virginia, founded in 1998 by Dr. Edward Martin and Mr. Alfred Giambone. The firm specializes in providing critical assistance to private sector clients, nonprofits, associations, and universities focused on federal healthcare delivery systems, public health programs, and government contracting. With over two dozen senior executive partners and more than 500 years of combined healthcare experience, MBA offers expertise in healthcare policy, program development, executive management, strategic planning, informatics, medical countermeasures, public health strategies, and emerging infectious diseases. The firm is committed to professionalism, ethical service, and delivering results for clients in both the public and private sectors.

Member
Cellphire Therapeutics, Inc.

Cellphire Therapeutics' vision is that no-one should die from controllable hemorrhage. In the US, hemorrhage remains a leading cause of preventable death for those under 45. For this reason, we need new products with improved hemostatic efficacy and ensure they are in the hands of clinicians when they are needed. The extremely short shelf-life – 7 days max – of platelets used as the standard of care Liquid Stored Platelets (LSP) gives rise to an inability to create an inventory buffer to address any increase in demand, particularly mass casualty events, military conflicts or significant hemorrhage situations such as post-partum hemorrhage and traumatic injury. This means: 1) Platelet rationing occurs across the system. 2) Nearly 400,000 platelet units a year expire before they can get to a patient in need. 3) Ten million Americans on anti-platelet or anticoagulant medications face greater risks when effective therapies aren’t available to clinicians, complicating surgery and trauma care.

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