Clinical Research Organizations (CRO)

CROs deliver integrated, Good Clinical Practice–compliant services including protocol design, site and investigator management, biostatistics, safety monitoring, and regulatory submissions (IND/IDE). They enable rigorous evaluation of combat casualty countermeasures, antimicrobials, regenerative therapies, telemedicine platforms, and diagnostics under austere, prolonged-field-care, and delayed-evacuation conditions.

Technical Challenges

  • Complexity of polytrauma and blast injury endpoints that reduce trial signal and require specialized outcome measures.

  • Logistical constraints in austere and prolonged-field-care settings that impede standardized data capture and follow-up.

  • Regulatory and ethical hurdles for expeditionary trials, emergency use, and IND/IDE pathways in military populations.

  • Integration of heterogeneous data (wearables, ePRO, imaging, biomarkers) into validated clinical endpoints.

Emerging Opportunities

  • Validated, deployable outcome measures tailored to combat injuries and prolonged evacuation timelines.

  • Rapid-start trial infrastructure for surge testing during outbreaks or operational deployments.

  • Harmonized data standards and interoperable platforms to aggregate real-world evidence from forward environments.

  • Streamlined DoD–FDA regulatory engagement models for combination products and novel biologics in combat care.

Current and Emerging Technologies in Clinical Research Organizations (CRO)

Decentralized and hybrid trial platforms

Remote site activation, teleconsent, mobile phlebotomy, and field-capable trial workflows reduce reliance on fixed clinical sites and support continuity in distributed or deployed cohorts.

Wearables, biosensors, and ePRO integration

Continuous physiological monitoring (hemodynamics, activity, sleep, wound sensors) and electronic patient-reported outcomes enable objective, remote endpoints relevant to readiness and recovery.

Adaptive designs and Bayesian statistics

Platform trials, adaptive randomization, and Bayesian approaches accelerate decision-making, reduce sample sizes, and allow efficient evaluation of multiple interventions during force health emergencies.

Integrated data platforms and real-world evidence

FHIR-compatible data lakes, secure cloud analytics, and linkage with clinical registries enable longitudinal safety surveillance, comparative effectiveness, and rapid signal detection in operational populations.

Accelerated regulatory pathways and CMC innovations

Early regulatory engagement, master files, and streamlined Chemistry, Manufacturing, and Controls (CMC) strategies are vital for field-deployable biologics, antimicrobial agents, and novel devices.

Importance to Military Medicine

Accelerates translation of battlefield solutions

Rapid, rigorous trials shorten timelines from prototype to deployed countermeasure for hemorrhage control, REBOA adjuncts, and wound therapies.

Enables evidence-based prolonged and austere care

Validates interventions for delayed evacuation, telemedicine systems, and field-capable diagnostics critical to survival and functional recovery.

Supports readiness and force health protection

Robust safety surveillance and interoperable data inform preventive strategies against infectious threats, AMR, and operational stressors.

Ensures regulatory and ethical compliance

GCP oversight and coordinated DoD–FDA engagement reduce downstream deployment risk and expedite fielding of validated technologies.

Alignment with the MTEC Mission

Directly advances MTEC’s mission to accelerate medical innovations for Warfighters by providing the clinical and regulatory pathway to field-ready solutions.

Bridges multidisciplinary MTEC portfolios—trauma, infectious disease, regenerative medicine, and telehealth—into validated products with civilian health benefit.

Supports DoD priorities for readiness by enabling rapid-response clinical studies during outbreaks, deployments, and surge events.

Dual-Use (Military + Civilian) Applications

Combat casualty care: trials for hemorrhage control devices, infection control, wound healing biologics, and point-of-injury diagnostics.

Infectious disease and biodefense: vaccine and therapeutic evaluation, platform trials during outbreaks, and AMR countermeasure studies.

Regenerative and reconstructive medicine: cell and tissue therapy safety/efficacy trials with functional recovery endpoints.

Prolonged and distributed care: validation of telehealth, remote monitoring, and decision-support tools used in delayed-evacuation or forward roles.

Explore MTEC Members with Clinical Research Organizations (CRO) Capabilities

MTEC members bring multidisciplinary strengths—clinical trial operations, regulatory affairs, DoD clinical site networks, biomarker development, and advanced analytics—that de-risk complex military-focused studies.

Explore member profiles to identify partners with field-tested trial logistics, adaptive design expertise, and secure data platforms that accelerate fielding of life-saving medical technologies.

147 Members with Clinical Research Organizations (CRO) capabilities.

The University of Texas System
The University of Texas System

The University of Texas System is a leading public university system in the United States, dedicated to improving lives through education, health care, and research. With over 256,000 students enrolled across 14 institutions, the UT System is committed to providing affordable access to higher education and producing a skilled workforce to drive Texas's economy.

IQVIA
IQVIA

IQVIA is a global leader in advanced analytics, technology solutions, and clinical research services for the life sciences industry. With a mission to accelerate innovation for a healthier world and a vision to power smarter healthcare for everyone, everywhere, IQVIA leverages unparalleled data, transformative technology, and deep healthcare expertise to drive better patient outcomes. Operating in over 100 countries with approximately 88,000 employees, IQVIA supports pharmaceutical, biotech, medtech, public health, and government organizations with a comprehensive portfolio of services and solutions. The company is recognized for its Connected Intelligence™, healthcare-grade AI, and commitment to sustainability, innovation, and evidence-based insights that shape the future of healthcare globally. IQVIA is also dedicated to reducing health inequities and driving sustainable change through innovation, collaboration, and data-driven solutions, partnering with organizations worldwide to address complex healthcare challenges.

Georgia Southern University
Georgia Southern University

Georgia Southern University is a vibrant institution with over 26,100 students across three campuses in Statesboro, Savannah, and Hinesville. The university offers 132 degree programs at the associate, bachelor’s, master’s, and doctorate levels, emphasizing student success, community impact, and research excellence. With a commitment to inclusivity and engagement, Georgia Southern fosters a supportive environment for diverse learners, including military-affiliated and adult students. The university is dedicated to transforming lives through education and community engagement, aligning its programs with regional needs. Additionally, Georgia Southern provides accelerated pathways for students to fast-track their master's degrees, enhancing educational opportunities. The university also emphasizes career readiness and public impact research, preparing students for successful careers and contributing to community development.

Institutes for Behavior Resources, Inc.
Institutes for Behavior Resources, Inc.

Founded in 1960 by Dr. Joseph V. Brady, the Institutes for Behavior Resources, Inc. (IBR) is a nonprofit organization dedicated to enhancing the growth of behavioral sciences and their application to human affairs through research, clinical services, and educational initiatives. IBR focuses on addressing social challenges through innovative research and comprehensive health services.

Alithia Life Sciences
Alithia Life Sciences

Alithia Life Sciences is an Australian-owned, boutique, full-service Contract Research Organization (CRO) dedicated to supporting pharmaceutical, biotechnology, device companies, and institutional research groups with their projects in Australia and beyond. With over 25 years of operational expertise across a wide range of therapeutic areas, Alithia offers personalized project management from Phase I to Phase III, aiming to deliver efficient project outcomes, add value to client programs, and ultimately improve human health and wellbeing.

Massachusetts General Hospital (Mass General)
Massachusetts General Hospital (Mass General)

Massachusetts General Hospital (Mass General) is a world-renowned academic medical center and the original and largest teaching hospital of Harvard Medical School. Mass General is recognized for its commitment to high-quality patient care, innovative research, and comprehensive educational opportunities. The hospital operates the largest hospital-based research program in the United States, fostering collaboration among leading clinicians and scientists to bridge innovation science with state-of-the-art clinical medicine. Mass General for Children (MGfC) is a leader in pediatric care, offering more than 50 medical specialties and 15 surgical services, and is home to the only proton beam facility in New England. The hospital is dedicated to serving local and global communities, training the next generation of healthcare professionals, and advancing medical knowledge through groundbreaking research, multidisciplinary care, and a strong commitment to family-centered and equitable healthcare.

Danforth Advisors
Danforth Advisors

Danforth Advisors is a strategic and operational consulting firm dedicated to supporting life science companies. They provide a comprehensive range of services tailored to the unique needs of biotech and pharmaceutical companies, from operational finance and accounting to clinical development and regulatory affairs. Their mission is to empower clients with expert guidance and flexible solutions that advance scientific innovation and drive business success.

The University of Texas at San Antonio
The University of Texas at San Antonio

The University of Texas at San Antonio (UTSA) is dedicated to the advancement of knowledge through research, teaching, and community engagement. As a premier public research university, UTSA embraces multicultural traditions and serves as a catalyst for socioeconomic development, providing access to educational excellence and preparing citizen leaders for the global environment.

Auburn University
Auburn University

Auburn University Research & Economic Development is dedicated to advancing research and economic growth through a collaborative effort among its various colleges and departments. The organization focuses on fostering innovation, supporting faculty and student research, and facilitating partnerships with industry and government to address societal challenges and enhance the quality of life. Recent initiatives include the launch of the Team Science Series to promote interdisciplinary collaboration and the development of the Gulf Coast Engineering Research Station to address coastal environmental challenges.

Deloitte
Deloitte

Deloitte is a leading global provider of audit, consulting, tax, and advisory services. The company is committed to improving public outcomes through a focus on people and developing relevant, timely, and sustainable solutions for clients. Deloitte's mission is to lead with purpose and drive positive change for people and communities, with a strong emphasis on social impact, sustainability, equity, and trust. Deloitte is also dedicated to helping the power, utilities, and renewables industry grow to become more sustainable, safe, and efficient, and is a fierce champion of industrials, inspiring optimism for the future.

University of Arkansas
University of Arkansas

The Institute for Integrative & Innovative Research (I3R) at the University of Arkansas is dedicated to pioneering solutions to complex societal challenges through convergence research. With a mission to advance research excellence and stimulate economic development, I3R focuses on deploying innovations at scale through collaboration across various sectors, including academia, industry, and government.

The University of Texas Medical Branch at Galveston
The University of Texas Medical Branch at Galveston

UTMB is dedicated to supporting research, education, and scholarly endeavors, with a focus on creating the future of healthcare through innovative research and community engagement.

ATCC (American Type Culture Collection)
ATCC (American Type Culture Collection)

ATCC is a nonprofit biological resource center, with a nearly century-long legacy supporting public health, biodefense, and global health security. ATCC provides critical infrastructure for infectious disease research and CBR threat response. Our biorepository operations support federal agencies, academia, and industry through secure specimen handling, reagent authentication, and global distribution. ATCC manages over 22 million vials under federal contracts, including repositories for NIAID, CDC, BARDA, NCI, FDA, and USDA. These programs enable rapid deployment of validated biological materials for vaccine development, diagnostic assay verification, and therapeutic screening against high-consequence pathogens such as SARS-CoV-2. Certified under ISO 9001, 13485, 17025, and 17034, ATCC ensures quality, traceability, and regulatory compliance across its operations. Our high-containment laboratories (BSL-2 and BSL-3, with access to BSL-4 through partners) and Select Agent license position us to support MTEC-aligned efforts in emerging infectious diseases and medical countermeasure development for CBRN threats.

The University of Queensland
The University of Queensland

The University of Queensland (UQ) is one of Australia's leading research and teaching institutions, dedicated to transforming lives through education and research. UQ aims to create a better future by equipping students with the skills and knowledge necessary for their chosen careers, while also addressing some of the world's most complex challenges through innovative research.

The University of Chicago
The University of Chicago

The University of Chicago is a prestigious urban research university committed to rigorous inquiry and intellectual freedom. Founded in 1890, it has produced numerous Nobel laureates and is known for its transformative education and groundbreaking research across various fields. The university fosters an inclusive and diverse learning environment, encouraging participation from all community members.

Clinical Research Strategies
Clinical Research Strategies

Clinical Research Strategies (CRS) is a Pittsburgh-based contract research organization and executive management consultancy dedicated to improving the performance of start-up and mid-size life sciences companies. With a focus on instilling fiscal discipline and reducing risks in clinical development, corporate affairs, and quality assurance programs, CRS provides tailored consulting and staffing solutions to navigate the complexities of regulatory pathways and ensure successful product launches. CRS is also committed to leveraging advancements in artificial intelligence and machine learning to enhance clinical research and regulatory processes.

We are here to help

Can’t find what you’re looking for?

Projects

Technology Showcase

See All Projects

Arizona State University

ASU Crosscutting Technologies to Enhance Military Medical Readiness and Resilience

Dr. Rachel Cassalia leads MTEC-supported efforts at ASU to shift military health from reactive care to proactive readiness through data-driven prevention.

University of Pittsburgh

Topical Metformin Lotion for Tendinopathy Prevention

University of Pittsburgh study shows topical metformin prevents overuse tendon injury. This work was sponsored through MTEC project 22-02-MPAI-014.

Theradaptive

Theradaptive’s RESTORE Trial Initiation for OsteoAdapt™ DE

Theradaptive launches RESTORE Phase I/II trial of OsteoAdapt™ DE for faster, precision bone healing in craniofacial injuries. MTEC-funded study targets improved recovery for military and civilian patients.

Altec

Autonomous Rehabilitation Device for Improved Recovery in Warfighters

The OSCIR platform—developed by Altec Inc in collaboration with the Naval Health Research Center—is bringing clinical-grade, real-time movement analysis to the front lines. Funded under MTEC-22-02-MPAI

JOIN OUR MAILING LIST

Stay Connected with MTEC

Keep up with active and upcoming solicitations, MTEC news and other valuable information.