RJH Biosciences
RJH Biosciences is a biotechnology company based in Edmonton, Alberta, Canada, specializing in developing novel transfection reagents and delivery systems for nucleic acids. They serve biomedical R&D, preclinical, and clinical applications, offering products, services, and partnerships to advance nucleic acid therapeutics and research.
Industries
Nr. of Employees
small (1-50)
RJH Biosciences
Edmonton, Alberta, Canada, North America
Products
Reagents for mRNA delivery (in vitro and in vivo configurations)
Delivery reagents and kits optimized for mRNA transfection in adherent and suspension cells, with kit options that include a transfection enhancer to increase efficiency in hard-to-transfect cells and in vivo formulations for animal studies.
Reagents for plasmid DNA (pDNA) delivery
Broadly acting reagents and kit configurations for plasmid DNA transfection across a range of cell lines and primary cells, plus in vivo formulations for animal model delivery.
Reagents for siRNA, microRNA and ASO delivery
Formulations targeted to small RNA delivery in suspension and adherent cells, with in vivo-capable variants and product bundles for hard-to-transfect cell types.
RNP delivery reagent for CRISPR applications
Formulation optimized for delivery of CRISPR-Cas9 ribonucleoprotein complexes to support genome editing workflows in both adherent and suspension cells under cell culture conditions.
Reagents for mRNA delivery (in vitro and in vivo configurations)
Delivery reagents and kits optimized for mRNA transfection in adherent and suspension cells, with kit options that include a transfection enhancer to increase efficiency in hard-to-transfect cells and in vivo formulations for animal studies.
Reagents for plasmid DNA (pDNA) delivery
Broadly acting reagents and kit configurations for plasmid DNA transfection across a range of cell lines and primary cells, plus in vivo formulations for animal model delivery.
Reagents for siRNA, microRNA and ASO delivery
Formulations targeted to small RNA delivery in suspension and adherent cells, with in vivo-capable variants and product bundles for hard-to-transfect cell types.
RNP delivery reagent for CRISPR applications
Formulation optimized for delivery of CRISPR-Cas9 ribonucleoprotein complexes to support genome editing workflows in both adherent and suspension cells under cell culture conditions.
Services
Transfection reagent screening service
Screening of multiple reagent formulations against a user-specified or in-house nucleic acid and cell type to identify optimal reagents using functional assays (transgene expression, gene silencing, cell viability).
R&D validation and functional assay services
Validation studies to establish construct functionality or validate new nucleic acid technologies, including reporter assays, gene silencing validation, and limited animal studies where appropriate.
Preclinical delivery and biodistribution studies
Preclinical evaluation of nucleic acid delivery systems in rodent models including local and systemic administration routes and biodistribution assessment.
Clinical development support (scale-up and safety studies)
Assistance with scaled-up synthesis of delivery systems, reproducibility assessment across batch scales and undertaking nonclinical safety/toxicology studies to support clinical translation.
Transfection reagent screening service
Screening of multiple reagent formulations against a user-specified or in-house nucleic acid and cell type to identify optimal reagents using functional assays (transgene expression, gene silencing, cell viability).
R&D validation and functional assay services
Validation studies to establish construct functionality or validate new nucleic acid technologies, including reporter assays, gene silencing validation, and limited animal studies where appropriate.
Preclinical delivery and biodistribution studies
Preclinical evaluation of nucleic acid delivery systems in rodent models including local and systemic administration routes and biodistribution assessment.
Clinical development support (scale-up and safety studies)
Assistance with scaled-up synthesis of delivery systems, reproducibility assessment across batch scales and undertaking nonclinical safety/toxicology studies to support clinical translation.
Expertise Areas
- Transfection reagent development
- Nucleic acid delivery (mRNA, siRNA, pDNA, ASO, microRNA)
- Preclinical in vivo delivery and biodistribution
- R&D screening and validation services for transfection
Key Technologies
- Cationic lipopolymer-based delivery
- Lipid-polymer hybrid vectors
- mRNA delivery
- siRNA/RNAi delivery