Altogen Biosystem
Supplier of non-viral transfection reagents and provider of preclinical GLP contract research services. Develops cell-line–specific in vitro transfection reagents and tissue-targeted in vivo delivery formulations (lipid, PEGylated liposomes, polymer and nanoparticle platforms). Offers validated preclinical models and assays for efficacy and toxicology assessment, and supplies downloadable protocols, safety documentation and online experimental tools.
Industries
Nr. of Employees
medium (51-250)
Altogen Biosystem
Products
Brain in vivo transfection kit
Nanoparticle/liposome-based reagent formulated for delivery of nucleic acids and proteins into mouse and rat brain; supplied with validated administration protocols and safety documentation.
Lungs (pulmonary) in vivo transfection kit
Formulation for intranasal or inhalation administration to deliver proteins, nucleic acids and small molecules to lung tissue and tumors in mice and rats; supplied with protocols and safety data.
Liver in vivo transfection kit
Biodegradable lipid/liposome reagent for systemic or intratumoral delivery to liver tissue and liver tumors; documents serum stability for conjugated complexes and includes validated administration protocols.
Lipid-based in vivo transfection reagent (broad)
Cationic lipid liposome reagent and enhancer formulated for tissue-targeted in vivo delivery of siRNA and plasmid DNA with reported functional validation in rodents and minimal immune response.
Kidney-targeted in vivo transfection kit
Nanoparticle-based liposomal reagent reported to be serum-stable for 24 hours and validated for efficient delivery of small RNAs, mRNA and plasmid DNA to kidney tissue and tumors via systemic or intratumoral administration.
Polymer-based in vivo transfection reagent
Biodegradable polymer-based reagent intended for efficient siRNA and plasmid DNA delivery to multiple organs (lung, liver, kidney, spleen) with minimal inflammatory response; supplied with protocols and safety documentation.
Brain in vivo transfection kit
Nanoparticle/liposome-based reagent formulated for delivery of nucleic acids and proteins into mouse and rat brain; supplied with validated administration protocols and safety documentation.
Lungs (pulmonary) in vivo transfection kit
Formulation for intranasal or inhalation administration to deliver proteins, nucleic acids and small molecules to lung tissue and tumors in mice and rats; supplied with protocols and safety data.
Liver in vivo transfection kit
Biodegradable lipid/liposome reagent for systemic or intratumoral delivery to liver tissue and liver tumors; documents serum stability for conjugated complexes and includes validated administration protocols.
Lipid-based in vivo transfection reagent (broad)
Cationic lipid liposome reagent and enhancer formulated for tissue-targeted in vivo delivery of siRNA and plasmid DNA with reported functional validation in rodents and minimal immune response.
Kidney-targeted in vivo transfection kit
Nanoparticle-based liposomal reagent reported to be serum-stable for 24 hours and validated for efficient delivery of small RNAs, mRNA and plasmid DNA to kidney tissue and tumors via systemic or intratumoral administration.
Polymer-based in vivo transfection reagent
Biodegradable polymer-based reagent intended for efficient siRNA and plasmid DNA delivery to multiple organs (lung, liver, kidney, spleen) with minimal inflammatory response; supplied with protocols and safety documentation.
Services
Contract laboratory services for preclinical testing including xenograft efficacy studies, immuno-oncology studies with humanized models, safety/toxicology studies to support regulatory submissions, assay development and stable cell line derivation.
Contract laboratory services for preclinical testing including xenograft efficacy studies, immuno-oncology studies with humanized models, safety/toxicology studies to support regulatory submissions, assay development and stable cell line derivation.
Expertise Areas
- Non-viral nucleic acid delivery
- Tissue-targeted in vivo delivery formulation (lipid, PEG-liposome, polymer, nanoparticle)
- Preclinical GLP study execution and model use (xenograft, humanized models)
- Cell-line–specific transfection optimization
Key Technologies
- Lipid-based nanoparticles
- PEGylated liposomes
- Biodegradable polymer carriers (PLGA, PBAE or similar)
- Polymer- or lipid-stabilized nanoparticles
News & Updates
In vivo transfection reagents and delivery kits have been cited or used in multiple peer-reviewed publications across journals such as Nature, Nature Biotechnology, Molecular Therapy, PLoS Pathogens and others.
In vivo transfection reagents and delivery kits have been cited or used in multiple peer-reviewed publications across journals such as Nature, Nature Biotechnology, Molecular Therapy, PLoS Pathogens and others.