General Therapeutics, Inc.
Developer of non-viral RNA delivery technologies focused on ionizable lipid chemistry and lipid nanoparticle (LNP) formulations for in vitro and in vivo research. Offers ready-to-use LNP transfection kits, custom formulation and manufacturing services, and licensing for proprietary ionizable lipids. Reports preclinical performance data showing increased protein expression and reduced inflammatory/reactogenic responses relative to traditional LNPs.
Industries
N/A
Products
Ready-to-use LNP transfection kits (multiple organ-targeting variants)
Pre-formulated LNP kits intended for rapid RNA encapsulation and delivery in both in vitro and in vivo experiments. Variants are formulated for general use and for targeting liver, spleen, lung, and hard-to-transfect cells.
Ready-to-use LNP transfection kits (multiple organ-targeting variants)
Pre-formulated LNP kits intended for rapid RNA encapsulation and delivery in both in vitro and in vivo experiments. Variants are formulated for general use and for targeting liver, spleen, lung, and hard-to-transfect cells.
Services
Custom LNP formulation and consultation
Project-specific formulation development, expert consultation, and guidance to select or optimize LNP compositions for research needs.
Large-scale lipid manufacturing and licensing
Provision of large-scale production of proprietary ionizable lipids and licensing arrangements for lipid chemistries.
Validation and performance testing support
Support for preclinical validation, including assay guidance and benchmarking in cell and animal models.
Custom LNP formulation and consultation
Project-specific formulation development, expert consultation, and guidance to select or optimize LNP compositions for research needs.
Large-scale lipid manufacturing and licensing
Provision of large-scale production of proprietary ionizable lipids and licensing arrangements for lipid chemistries.
Validation and performance testing support
Support for preclinical validation, including assay guidance and benchmarking in cell and animal models.
Expertise Areas
- Non-viral RNA delivery
- Lipid nanoparticle (LNP) formulation
- Ionizable lipid chemistry
- Preclinical in vitro and in vivo transfection
Key Technologies
- Ionizable lipid chemistry
- Lipid nanoparticle (LNP) formulation
- Non-SORT organ targeting
- mRNA/siRNA/saRNA encapsulation