Vectalys
Provider of lentiviral-based delivery technologies and CDMO services for research, pre-clinical and clinical gene & cell therapy. Offers integrative lentiviral vector design and production, a non-integrative RNA delivery particle format for transient expression, purification and titration methods to maximize functional particle quality, and scale-up/GMP manufacturing support.
Industries
Nr. of Employees
small (1-50)
Products
Ready-to-use integrative lentiviral particles (reporters and gene editing)
Pre-made integrative lentiviral particle products including fluorescent reporters, bioluminescent reporters, and vectors configured for gene editing or specific promoters for rapid testing and assays.
Ready-to-use non-integrative RNA lentiviral particles (reporters, Cre, Cas9)
Pre-made non-integrative RNA-packaging particles for transient expression including luciferase reporter, recombinase and nuclease mRNA formats for gene editing tests and in vivo/transient applications.
Plasmid packaging mixes for non-integrative RNA particle production
Plasmid kits and packaging mixes enabling in-lab production of non-integrative RNA-packaging particles for academic research use.
Ready-to-use integrative lentiviral particles (reporters and gene editing)
Pre-made integrative lentiviral particle products including fluorescent reporters, bioluminescent reporters, and vectors configured for gene editing or specific promoters for rapid testing and assays.
Ready-to-use non-integrative RNA lentiviral particles (reporters, Cre, Cas9)
Pre-made non-integrative RNA-packaging particles for transient expression including luciferase reporter, recombinase and nuclease mRNA formats for gene editing tests and in vivo/transient applications.
Plasmid packaging mixes for non-integrative RNA particle production
Plasmid kits and packaging mixes enabling in-lab production of non-integrative RNA-packaging particles for academic research use.
Services
Custom integrative lentiviral vector production (research → clinical)
Design and manufacture of custom integrative lentiviral vectors with selectable purification/quality tiers for applications from cell line generation to in vivo experiments; scale-up and GMP transfer available.
Custom non-integrative RNA particle production (transient RNA delivery)
Production of highly purified non-integrative RNA-packaging particles for transient expression and multiplex RNA delivery (e.g., sgRNA, Cas9 mRNA, antigens), with premium purification for sensitive cell types.
Large-scale and pre-clinical vector manufacturing
Production of larger batch volumes with consistent titer and purity for pre-clinical studies and animal models, enabling use of the same vector composition from research to pre-clinical stages.
GMP manufacturing and transfer for clinical studies
Stepwise qualification plan and GMP-grade production capabilities (including partnership-operated GMP facilities) for clinical-grade lentiviral and RNA particle manufacturing and associated quality control.
Technical support, project management and experimental design
Advisory and hands-on support for vector construction choices, purification level selection, titration strategy and downstream experimental design to maximize transduction efficiency and preserve cell phenotype.
Custom integrative lentiviral vector production (research → clinical)
Design and manufacture of custom integrative lentiviral vectors with selectable purification/quality tiers for applications from cell line generation to in vivo experiments; scale-up and GMP transfer available.
Custom non-integrative RNA particle production (transient RNA delivery)
Production of highly purified non-integrative RNA-packaging particles for transient expression and multiplex RNA delivery (e.g., sgRNA, Cas9 mRNA, antigens), with premium purification for sensitive cell types.
Large-scale and pre-clinical vector manufacturing
Production of larger batch volumes with consistent titer and purity for pre-clinical studies and animal models, enabling use of the same vector composition from research to pre-clinical stages.
GMP manufacturing and transfer for clinical studies
Stepwise qualification plan and GMP-grade production capabilities (including partnership-operated GMP facilities) for clinical-grade lentiviral and RNA particle manufacturing and associated quality control.
Technical support, project management and experimental design
Advisory and hands-on support for vector construction choices, purification level selection, titration strategy and downstream experimental design to maximize transduction efficiency and preserve cell phenotype.
Expertise Areas
- Lentiviral vector manufacturing (integrative and non-integrative)
- Transient RNA delivery for gene editing
- Cell and gene therapy CDMO services (scale-up and GMP transition)
- Immunotherapy and CAR‑T/NK cell transduction
Key Technologies
- Integrative lentiviral vectors
- Non-integrative RNA-packaging lentiviral particles (bacteriophage coat-based)
- CRISPR-Cas9 RNA delivery
- VSV-G pseudotyping