Paragonix Technologies
Developer and provider of controlled hypothermic organ preservation systems, portable perfusion devices, digital monitoring for real-time telemetry and case coordination, nationwide clinical procurement support, and organ-specific registries for post-transplant outcomes and real-world evidence. Company-reported metrics include more than 20,000 donor organs preserved, support for over 250 transplant centers, and over 35 clinical studies.
Industries
Nr. of Employees
medium (51-250)
Paragonix Technologies
Waltham, Massachusetts, United States
Patents
Products
Cardiac controlled hypothermic transport system
Sterile transport device designed to suspend and maintain donor hearts in a pressure-controlled canister with validated temperature stabilization and telemetry reporting during transit.
Lung transport system with automated airway pressure regulation
Donor lung transport system that maintains consistent thermal conditions and actively monitors and regulates airway inflation pressure while transmitting temperature, pressure and location data.
Portable renal perfusion system
Portable renal perfusion device engineered for continuous hypothermic perfusion of kidneys during transport with integrated monitoring and remote telemetry, enabling extended preservation and multi-segment transport including commercial flights.
Static hypothermic preservation systems for liver and pancreas
Transport devices designed to maintain donor livers and pancreases at validated hypothermic conditions with embedded temperature monitoring and telemetry for extended transport scenarios.
Cardiac controlled hypothermic transport system
Sterile transport device designed to suspend and maintain donor hearts in a pressure-controlled canister with validated temperature stabilization and telemetry reporting during transit.
Lung transport system with automated airway pressure regulation
Donor lung transport system that maintains consistent thermal conditions and actively monitors and regulates airway inflation pressure while transmitting temperature, pressure and location data.
Portable renal perfusion system
Portable renal perfusion device engineered for continuous hypothermic perfusion of kidneys during transport with integrated monitoring and remote telemetry, enabling extended preservation and multi-segment transport including commercial flights.
Static hypothermic preservation systems for liver and pancreas
Transport devices designed to maintain donor livers and pancreases at validated hypothermic conditions with embedded temperature monitoring and telemetry for extended transport scenarios.
Services
Mobile and web platform providing real-time device telemetry (temperature, pressure), GPS tracking, secure messaging, and case timelines to coordinate transplant teams and support remote participation.
24/7 on-call clinical support with trained procurement surgeons, preservationists, surgical assistants, and regional deployment hubs to provide on-site procurement assistance and organ delivery logistics.
Organ-specific observational registries that collect retrospective and prospective post-transplant outcome data to evaluate preservation performance and support comparative effectiveness research.
Regular podcast series and multimedia content covering transplantation topics, clinical research summaries, logistics and interviews with clinicians and stakeholders aimed at clinical education and stakeholder outreach.
Mobile and web platform providing real-time device telemetry (temperature, pressure), GPS tracking, secure messaging, and case timelines to coordinate transplant teams and support remote participation.
24/7 on-call clinical support with trained procurement surgeons, preservationists, surgical assistants, and regional deployment hubs to provide on-site procurement assistance and organ delivery logistics.
Organ-specific observational registries that collect retrospective and prospective post-transplant outcome data to evaluate preservation performance and support comparative effectiveness research.
Regular podcast series and multimedia content covering transplantation topics, clinical research summaries, logistics and interviews with clinicians and stakeholders aimed at clinical education and stakeholder outreach.
Expertise Areas
- Organ preservation device development
- Hypothermic machine perfusion for renal transplantation
- Static hypothermic preservation for heart, lung, liver and pancreas
- Real-time telemetry and digital case coordination for transplant logistics
Key Technologies
- Controlled hypothermic preservation
- Hypothermic machine perfusion
- Phase-change thermal materials
- Automated airway pressure control
News & Updates
Report of a donor kidney that remained on continuous perfusion across multiple handoffs and commercial flights, enabling reallocation after an out-of-state decline and resulting in successful transplantation.
Case report of a donor kidney continuously perfused for over 30 hours on a portable renal perfusion system with successful transplantation after prolonged cold ischemic time.
Announcement of multiple device approvals and conformity decisions including EU MDR approvals and various regulatory clearances enabling clinical and commercial availability.
Presentations and publications from registry and clinical study data showing reductions in rehospitalization and complications for lung and liver recipients and improved survival metrics for heart transplant recipients using controlled preservation methods.
Regulatory clearance granted for a portable renal perfusion device enabling continuous perfusion transport of donor kidneys.
Announcement of a clinical trial collaboration focused on donation after circulatory death (DCD) heart utilization and evaluation of advanced preservation methods.
Report of a donor kidney that remained on continuous perfusion across multiple handoffs and commercial flights, enabling reallocation after an out-of-state decline and resulting in successful transplantation.
Case report of a donor kidney continuously perfused for over 30 hours on a portable renal perfusion system with successful transplantation after prolonged cold ischemic time.
Announcement of multiple device approvals and conformity decisions including EU MDR approvals and various regulatory clearances enabling clinical and commercial availability.
Presentations and publications from registry and clinical study data showing reductions in rehospitalization and complications for lung and liver recipients and improved survival metrics for heart transplant recipients using controlled preservation methods.
Regulatory clearance granted for a portable renal perfusion device enabling continuous perfusion transport of donor kidneys.
Announcement of a clinical trial collaboration focused on donation after circulatory death (DCD) heart utilization and evaluation of advanced preservation methods.