System for hypothermic transport of samples

Inventors

Anderson, Lisa MariaJudson, Jared Alden

Assignees

Paragonix Technologies Inc

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Publication Number

US-12121023-B1

Patent

Publication Date

2024-10-22

Expiration Date


Abstract

A system for the hypothermic transport of biological samples, such as tissues, organs, or body fluids. The system includes a self-purging preservation apparatus to suspend a sample in preservation fluid and perfuse a tissue with preservation fluid. The self-purging preservation apparatus is placed in an insulated transport container having a cooling medium. When assembled, the system allows for transport of biological samples for extended periods of time at a stable temperature.

Core Innovation

The invention provides a system for hypothermic transport of an organ using a transport container that includes a floor and walls. Eutectic cooling blocks are arranged within recesses positioned along inside surfaces of the interior of the transport container, and the eutectic cooling blocks are engineered to have a temperature of 2-8°C. The eutectic cooling blocks are configured to maintain a temperature within the interior of the transport container within an acceptable range during transport.

The system further includes a basket configured to support the organ. The basket is disposed within the interior of the transport container and corresponds in size and shape to a perimeter of the interior so that lateral movement of the basket is limited. The basket comprises a plurality of vertically extending ribs configured to secure the basket to inside surfaces of the walls of the transport container by abutting the inside surfaces of the walls of the transport container.

An insulated environment is formed within the transport container by a lid operable to couple with the walls. A temperature sensor is configured to measure a temperature within the interior of the transport container, and the temperature within the interior of the transport container is readable outside the insulated environment without opening the lid.

Claims Coverage

The partial content includes two independent claims (a system claim and a container claim). Each independent claim centers on maintaining an organ hypothermically using eutectic cooling blocks arranged in recesses, an organ-support basket with limited lateral movement, an insulated lid, and a temperature sensor readable from outside without opening the lid.

Eutectic cooling blocks in recesses within an insulated transport container

The transport container comprises a floor and walls, with eutectic cooling blocks arranged within recesses positioned along inside surfaces of the interior, wherein the eutectic cooling blocks are engineered to have a temperature of 2-8°C and are configured to maintain a temperature within the interior within an acceptable range during transport.

Basket sized to limit lateral movement with vertically extending ribs abutting wall inside surfaces

A basket configured to support the organ is disposed within the interior, where the basket corresponds in size and shape to a perimeter of the interior so that lateral movement is limited, and the basket comprises a plurality of vertically extending ribs configured to secure the basket to inside surfaces of the walls by abutting the inside surfaces of the walls.

Insulated lid and temperature sensor readable outside without opening the lid

A lid operable to couple with the walls forms an insulated environment within the transport container, and a temperature sensor measures a temperature within the interior wherein the temperature is readable outside the insulated environment without opening the lid.

Across both independent claims, the inventive coverage is directed to an insulated hypothermic transport container that uses eutectic cooling blocks positioned in interior recesses to maintain an acceptable temperature range, together with an organ-support basket configured to limit lateral movement and an externally readable temperature sensor without opening the lid.

Stated Advantages

Maintain a temperature within the interior of the transport container within an acceptable range during transport.

Temperature within the interior is readable outside the insulated environment without opening the lid.

Documented Applications

Hypothermic transport of an organ in a transport container for maintaining interior temperature within an acceptable range during transport.

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