System for hypothermic transport of samples
Inventors
Anderson, Lisa Maria • Judson, Jared Alden
Assignees
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Publication Number
US-12279610-B2
Publication Date
2025-04-22
Expiration Date
Abstract
A system for the hypothermic transport of biological samples, such as tissues, organs, or body fluids. The system includes a self-purging preservation apparatus to suspend a sample in preservation fluid and perfuse a tissue with preservation fluid. The self-purging preservation apparatus is placed in an insulated transport container having a cooling medium. When assembled, the system allows for transport of biological samples for extended periods of time at a stable temperature.
Core Innovation
The invention relates to a canister for transporting a biological sample in a sterile environment, with a removable lid that couples with the walls of a sample storage chamber to form the sterile environment. The removable lid includes a chamber, a fill port, a vent between the chamber and an exterior of the transport container, and a valve between the chamber and the sample storage chamber.
The valve and vent are arranged so that gases are purged from the sample chamber through the valve to the chamber and from the chamber through the vent to the exterior of the canister as the sample chamber is filled with fluid through the fill port. The invention further includes an adapter separate from the fill port and configured to couple to and suspend the biological sample from a bottom portion within the sterile environment, without the biological sample contacting the floor and the walls.
A temperature sensor is positioned within the sterile environment and is in communication with a temperature display readable outside the sterile environment without opening the removable lid. The canister additionally includes a plurality of cooling blocks positioned around an exterior of the canister.
Claims Coverage
The partial content includes one independent claim (clm-00001). Its inventive scope is centered on four inventive features: a self-purging sterile-sample transport lid architecture, a sample-suspending adapter, external-readable temperature monitoring, and exterior cooling blocks for hypothermic transport.
Sterile sample chamber with purging lid valve and vent during filling
A canister having a sample storage chamber, and a removable lid operable to couple with the walls to form a sterile environment, the removable lid including a chamber, a fill port, a vent between the chamber and an exterior of the transport container, and a valve between the chamber and the sample storage chamber, wherein the valve and vent are positioned to direct fluids in the sample chamber to the valve, allowing gases to be purged from the sample chamber through the valve to the chamber and from the chamber through the vent to the exterior of the canister as the sample chamber is filled with fluid through the fill port.
Sample suspension adapter without contacting floor and walls
An adapter, separate from the fill port, configured to couple to and suspend the biological sample from the bottom portion within the sterile environment without the biological sample contacting the floor and the walls.
External-readable temperature monitoring without opening the lid
A temperature sensor within the sterile environment and in communication with a temperature display readable outside the sterile environment without opening the removable lid.
Exterior cooling blocks for transport temperature control
A plurality of cooling blocks positioned around an exterior of the canister.
Overall, the independent claim covers a sterile transporting canister with a removable lid that purges gases through an arranged valve-and-vent pathway during filling, an adapter that suspends the sample without contact with chamber surfaces, a temperature sensor with an externally readable display without opening the lid, and cooling blocks positioned around the canister exterior.
Stated Advantages
Not explicitly described in patent.
Documented Applications
Not explicitly described in patent.
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