Gemini Biosciences
Gemini Biosciences Ltd is an innovative and reliable partner in life sciences and biomedical research, offering high-quality products and services to support research activities. The company develops and commercializes research products and services in proteomics, biochemistry, molecular biology, structural biology, metabolomics, cell biology, and computational biology, aiming to make life sciences research easier, more reliable, and cost-effective.
Industries
Nr. of Employees
small (1-50)
Gemini Biosciences
Liverpool, Liverpool, United Kingdom, Europe
Products
Proteomics Services
Comprehensive proteomics services including experimental design, sample processing, mass spectrometry, and data analysis for protein identification and modification analysis.
Proteomics Services
Comprehensive proteomics services including experimental design, sample processing, mass spectrometry, and data analysis for protein identification and modification analysis.
Custom Antibodies
Development of custom polyclonal and monoclonal antibodies for various applications such as Western blotting and ELISA.
Custom Antibodies
Development of custom polyclonal and monoclonal antibodies for various applications such as Western blotting and ELISA.
Molecular Biology Services
Services including Next Generation Sequencing, DNA cloning, gene synthesis, and custom recombinant protein production.
Molecular Biology Services
Services including Next Generation Sequencing, DNA cloning, gene synthesis, and custom recombinant protein production.
Proteomics Services
Comprehensive proteomics services including experimental design, sample processing, mass spectrometry, and data analysis for protein identification and modification analysis.
Proteomics Services
Comprehensive proteomics services including experimental design, sample processing, mass spectrometry, and data analysis for protein identification and modification analysis.
Custom Antibodies
Development of custom polyclonal and monoclonal antibodies for various applications such as Western blotting and ELISA.
Custom Antibodies
Development of custom polyclonal and monoclonal antibodies for various applications such as Western blotting and ELISA.
Molecular Biology Services
Services including Next Generation Sequencing, DNA cloning, gene synthesis, and custom recombinant protein production.
Molecular Biology Services
Services including Next Generation Sequencing, DNA cloning, gene synthesis, and custom recombinant protein production.
Services
Quantitative proteomics analyses (SILAC, label-free, TMT)
Experimental design and execution of quantitative proteomics projects using SILAC, label-free, or TMT workflows with LC-MS/MS identification and relative quantitation.
Peptide mapping and PTM characterization (analytical and micro)
Analytical peptide mapping (HPLC-UV + LC-MS/MS) and micro peptide mapping (nanoLC-MS/MS) for primary sequence confirmation, PTM identification and comparability studies.
Disulfide bond mapping and free thiol assays
Analytical and micro disulfide mapping using LC-MS/MS combined with free thiol quantitation by colorimetric assay; semi-quantitative EIC options for limited sample amounts.
Epitope mapping (HDX-MS, peptide arrays, phage display)
Determination of antibody binding sites (linear, conformational, discontinuous) using HDX-MS, peptide array screening and phage display selection; typical project timelines and parallel screening options available.
Custom antibody production (polyclonal and monoclonal)
End-to-end custom antibody services including peptide antigen design and synthesis, use of recombinant protein antigens, host species selection (including mouse), immunization, hybridoma generation for monoclonals, and purification by protein A/G, antigen affinity or fractional precipitation.
Ascites production for monoclonal antibodies
Generation of high-titre monoclonal antibody ascitic fluid for projects where in vitro production is insufficient or unsuitable; service can use customer-supplied hybridoma lines.
Quantitative proteomics analyses (SILAC, label-free, TMT)
Experimental design and execution of quantitative proteomics projects using SILAC, label-free, or TMT workflows with LC-MS/MS identification and relative quantitation.
Peptide mapping and PTM characterization (analytical and micro)
Analytical peptide mapping (HPLC-UV + LC-MS/MS) and micro peptide mapping (nanoLC-MS/MS) for primary sequence confirmation, PTM identification and comparability studies.
Disulfide bond mapping and free thiol assays
Analytical and micro disulfide mapping using LC-MS/MS combined with free thiol quantitation by colorimetric assay; semi-quantitative EIC options for limited sample amounts.
Epitope mapping (HDX-MS, peptide arrays, phage display)
Determination of antibody binding sites (linear, conformational, discontinuous) using HDX-MS, peptide array screening and phage display selection; typical project timelines and parallel screening options available.
Custom antibody production (polyclonal and monoclonal)
End-to-end custom antibody services including peptide antigen design and synthesis, use of recombinant protein antigens, host species selection (including mouse), immunization, hybridoma generation for monoclonals, and purification by protein A/G, antigen affinity or fractional precipitation.
Ascites production for monoclonal antibodies
Generation of high-titre monoclonal antibody ascitic fluid for projects where in vitro production is insufficient or unsuitable; service can use customer-supplied hybridoma lines.
Expertise Areas
- Quantitative proteomics
- Mass spectrometry-based protein characterization
- Glycoproteomics and site-specific glycosylation analysis
- Antibody discovery and development
Key Technologies
- Liquid chromatography tandem mass spectrometry (LC-MS/MS)
- NanoLC-ESI-MS/MS
- Hydrogen-deuterium exchange mass spectrometry (HDX-MS)
- HILIC glycan separation