MtoZ-Biolabs


MtoZ Biolabs is an integrated contract research organization (CRO) specializing in proteomics, metabolomics, bioinformatics, biopharmaceutical analysis services, and advanced structural analysis. They utilize cutting-edge mass spectrometry and chromatography platforms to provide rapid, high-throughput, and cost-effective research solutions in biochemistry, biotechnology, and biopharmaceutical fields, supporting scientific discovery, development, and structural characterization.

Industries

Biopharma
Biotechnology
Life Science
Biotechnology Research

Nr. of Employees

small (1-50)

MtoZ-Biolabs

Boston, Massachusetts, United States, North America


Products

Bradford Protein

A rapid quantitative technique based on the color change that occurs when Coomassie Brilliant Blue G-250 binds to proteins, providing fast and simple protein quantification solutions for high-throughput screening.

Bradford Protein Quantification Kit

Exceptionally fast and easy-to-use protein quantification kit requiring only a 5-minute reaction time with excellent reagent stability.

GST Tagged Protein Purification

MtoZ Biolabs' GST Tagged Protein Purification Kit is designed for rapid purification of GST-tagged fusion proteins, efficiently obtaining high-purity recombinant proteins for enzymatic studies, interaction validation, and structural and functional analyses.

GST Tagged Protein Purification Column

Purification column tailored for GST-tagged proteins.

Lowry Protein

A classical, reliable protein quantification method based on the specific reaction between the Folin phenol reagent and proteins, utilizing a two-step color development process involving the biuret reaction and the Folin phenol reaction.

Lowry Protein Quantification Kit

Protein quantification kit known for outstanding accuracy, precision, low variability, and excellent reproducibility.

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Services

Ion-mobility-enhanced proteomics integrating ion mobility with LC–MS/MS to improve sensitivity, separate isomeric peptides and support low-input and high-throughput cohort studies. Deliverables include experimental procedures, instrument parameters, raw data and analysis reports.

Targeted absolute quantification using stable isotope-labeled synthetic peptides and SRM/MRM workflows to measure absolute protein and PTM levels from digested samples with quantitative reporting and raw data.

Single-cell immune-repertoire profiling including sample preparation, barcoded library construction, high-throughput sequencing and computational analysis to resolve T cell clonotypes at single-cell resolution.

Single-cell B cell receptor sequencing including cell enrichment, barcoded library preparation, high-throughput sequencing and bioinformatic analysis to profile BCR diversity and clonal evolution.

Workflows for protein digestion (including multiple proteases), peptide cleanup, LC separation, MS/MS identification and quantitative comparison (isobaric or label-free) with bioinformatic peptide-to-protein mapping and PTM detection.

Phosphoproteomics workflows combining enrichment, mass spectrometric identification and quantitative profiling to map signaling pathway changes and discover phosphorylation biomarkers.

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Expertise Areas

  • Mass spectrometry-based proteomics
  • Ion-mobility and high-throughput proteomics
  • Targeted and quantitative proteomics assay development
  • Post-translational modification (PTM) analysis and enrichment
  • Show More (6)

Key Technologies

  • Liquid chromatography–tandem mass spectrometry (LC–MS/MS)
  • MALDI‑TOF mass spectrometry
  • Ion mobility separation with serial fragmentation
  • High-resolution Orbitrap-class mass spectrometry
  • Show More (15)

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