IQ Proteomics


IQ Proteomics specializes in next-generation proteomic applications, offering optimized workflows for comprehensive and timely proteome characterization. Their services include discovery, targeted, and support proteomics, utilizing advanced technologies such as multiplexing with TMT™ reagents, PTMScan® technology, and real-time search MS3 or DIA acquisition. They focus on unbiased, proteome-wide, quantitative proteomics for drug target identification, biomarker discovery, and post-translational modifications, with a commitment to providing accurate, sensitive, and rapid quantification of biologically relevant targets. Established in 2015 and located near Boston, MA, IQ Proteomics has a proven track record of completing thousands of projects for major pharmaceutical and biotech companies.

Industries

biotechnology
information-technology-dbca

Nr. of Employees

small (1-50)

IQ Proteomics

39 Grant St. Suite 400, Framingham, MA 01702


Services

End-to-end discovery proteomics: project consultation and design, sample preparation, LC-MS data acquisition, data analysis, and delivery of QC metrics and annotated quantitative protein tables. Raw data and detailed methods available on request.

Custom targeted LC-MS assay development and execution for absolute and relative quantification, target engagement studies, and high-throughput sample analysis using targeted MS workflows and automated sample preparation.

Supplementary services including cell culture support, dedicated proteome informatics, instrument time (LC-MS acquisition of customer-prepared samples with flexible scheduling), and expedited processing options.

Expertise Areas

  • Quantitative proteomics (discovery and targeted)
  • Data-independent acquisition (DIA) workflows
  • Isobaric multiplexed proteomics
  • Post-translational modification analysis
  • Show More (7)

Key Technologies

  • High-resolution accurate-mass LC-MS/MS
  • Data-independent acquisition (DIA)
  • Data-dependent acquisition (DDA)
  • Isobaric labeling for multiplexed quantitation
  • Show More (8)

News & Updates

DIA acquisition via Orbitrap Astral provides deep coverage, faster project completion, and improved pricing, with notable figures of merit such as coverage of >10,000 proteins and a 5% median coefficient of variation.

The website has been completely redesigned to better showcase IQP's workflows, capabilities, and services.

IQP has onboarded an Orbitrap Astral with Tandem Neo high-throughput chromatography, broadening service offerings.

IQP will present posters on LC-MS applications for covalent inhibitor characterization.

IQP has moved to a purpose-built laboratory at 39 Grant St., Framingham, MA.

Study on understanding disease pathologies through localized biomolecular networks using enzymatic proximity techniques.

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