PolyQuant


Provider of mass spectrometry-based proteomics services, isotope‑labeled reference standards and bioinformatics support. Offers discovery and quantitative proteomics, custom and off‑the‑shelf isotope‑labeled standards (QconCATs and complete proteins), host cell protein (HCP) analysis workflows, assay development and method validation including GMP-transfer readiness. Services span research, biomarker validation, biopharmaceutical quality control and specialized applications (phage analytics, protease profiling).

Industries

Biotechnology
Biotechnology Research

Nr. of Employees

small (1-50)

PolyQuant


Patents

Bladder cancer biomarker proteins

US-11536724-B2

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Products

CHOcoCAT

Lyophilized heavy isotope-labeled concatenated peptide reference standard for targeted quantification of common CHO-derived host cell proteins (packaged for multiple applications).

EcoCAT

Lyophilized heavy isotope-labeled concatenated peptide standard for targeted quantification of E. coli-derived host cell proteins.

CVDQuant Kit

Reference peptide kit (multiple QconCATs) containing peptides for absolute quantification of a panel of plasma proteins linked to cardiovascular diseases, applicable to human, mouse and rat samples.

Cov-MS and Cov-MS-2 standards

Peptide and complete-protein reference standards (labeled and unlabeled) for MS-based detection and absolute quantification of SARS-CoV-2 and panels of respiratory viruses.

QconCAT product lines (Standard, Crude, Superior)

Custom-made concatenated peptide reference proteins available as crude extracts or purified proteins with selectable labeling and purification grades for quantification workflows.

QCAL calibration standards

Complete-protein and peptide-mix standards for instrument calibration and performance assessment (resolution, linearity, peptide modifications, chromatographic evaluation).

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Services

Unbiased protein identification and relative quantification using high-resolution LC-MS/MS; customized workflows and reporting.

End-to-end quantitative proteomics including bioinformatics, protocol development, QconCAT standard production, sample preparation, LC-MS/MS measurement and data analysis/reporting.

Untargeted and targeted HCP detection and quantification services (PurityQuant ID, PurityQuant) and custom HCP assay development with options for GMP-transfer.

Peptide mapping (basic and extended), intact-mass analysis, detection of PTMs and sample impurity profiling for biopharmaceutical QC.

Custom production of concatenated peptide reference proteins in multiple formats (crude, purified, labelled) with QC and delivery options for research and high-throughput applications.

Quantitative proteomics workflows for phage protein quantification, virion stoichiometry and host contaminant detection with GMP-conform options.

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Expertise Areas

  • Discovery proteomics
  • Quantitative proteomics and absolute protein quantification
  • Host cell protein (HCP) analysis for bioprocess QC
  • Targeted LC-MS/MS assay development
  • Show More (6)

Key Technologies

  • High-resolution LC-MS/MS
  • Targeted proteomics (PRM/MRM)
  • Data-independent acquisition (DIA/SWATH)
  • Stable isotope labeling (15N, 13C/15N Arg/Lys)
  • Show More (5)

News & Updates

Regular newsletter issues covering product launches, research highlights, application notes and special issues on topics such as HCP analysis, QconCAT workflows and Cov-MS developments.


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