PolyQuant
Provider of mass spectrometry-based proteomics services, custom isotope-labelled reference standards, and bioinformatics workflows. Offers discovery and targeted LC-MS/MS workflows, production of concatenated heavy‑isotope reference standards and stable isotope‑labelled proteins, assay development and validation, and off‑the‑shelf kits and calibration standards for research and regulated applications.
Industries
Nr. of Employees
small (1-50)
PolyQuant
Products
Custom QconCAT reference standards (concatenated proteotypic peptides)
Custom-made concatenated synthetic proteins containing up to ~50 heavy‑isotope‑labelled proteotypic peptides for absolute quantification by MS; available in different purity grades and labelling schemes.
CHO‑specific and E. coli‑specific HCP reference kits (heavy‑labelled)
Pre‑made heavy‑isotope‑labelled reference standards (QconCATs) targeted to common host cell proteins from CHO or E. coli to support targeted HCP quantification workflows.
Cardiovascular biomarker QconCAT kit
Multi‑QconCAT kit containing reference peptides for absolute quantification of a plasma biomarker panel across human, mouse and rat samples.
Retention time and instrument calibration standards
Peptide/protein standards for retention time normalization (retention time calibrants) and instrument performance assessment (QCAL) to support reproducible chromatographic separation and QC.
Viral peptide/protein reference standards for respiratory viruses
Peptide mixes and complete protein standards (labelled and unlabeled) for MS‑based detection and quantification of SARS‑CoV‑2 and other respiratory viruses (Influenza, RSV).
Recombinant tropoelastin (lyophilized) for research
Human recombinant tropoelastin supplied as sterile lyophilized protein for tissue engineering and cell culture applications (multiple package sizes).
Custom QconCAT reference standards (concatenated proteotypic peptides)
Custom-made concatenated synthetic proteins containing up to ~50 heavy‑isotope‑labelled proteotypic peptides for absolute quantification by MS; available in different purity grades and labelling schemes.
CHO‑specific and E. coli‑specific HCP reference kits (heavy‑labelled)
Pre‑made heavy‑isotope‑labelled reference standards (QconCATs) targeted to common host cell proteins from CHO or E. coli to support targeted HCP quantification workflows.
Cardiovascular biomarker QconCAT kit
Multi‑QconCAT kit containing reference peptides for absolute quantification of a plasma biomarker panel across human, mouse and rat samples.
Retention time and instrument calibration standards
Peptide/protein standards for retention time normalization (retention time calibrants) and instrument performance assessment (QCAL) to support reproducible chromatographic separation and QC.
Viral peptide/protein reference standards for respiratory viruses
Peptide mixes and complete protein standards (labelled and unlabeled) for MS‑based detection and quantification of SARS‑CoV‑2 and other respiratory viruses (Influenza, RSV).
Recombinant tropoelastin (lyophilized) for research
Human recombinant tropoelastin supplied as sterile lyophilized protein for tissue engineering and cell culture applications (multiple package sizes).
Services
Quantitative proteomics service (full service)
End‑to‑end service including bioinformatic analysis, extraction protocol development, production of reference standards, sample preparation, LC‑MS/MS measurement, data analysis and reporting.
Targeted proteomics and routine measurement service
Custom targeted LC‑MS/MS assay setup, routine sample measurement and high‑throughput targeted quantification using isotope‑labelled standards.
Host cell protein (HCP) analysis services
Untargeted and targeted HCP detection and absolute quantification workflows, custom HCP assay development and GMP‑transfer support.
Metaproteomics analysis
Proteome extraction, fractionation, LC‑MS/MS measurement and computational analysis for environmental and complex multi‑organism samples.
Phage and viral analytics
Quantitative proteomics and HCP analytics for phage/viral therapeutics including quality control and stoichiometry determination.
Assay development and validation (custom)
Custom assay development for new host systems, critical targets or regulatory requirements, including validation and GMP‑transfer.
Quantitative proteomics service (full service)
End‑to‑end service including bioinformatic analysis, extraction protocol development, production of reference standards, sample preparation, LC‑MS/MS measurement, data analysis and reporting.
Targeted proteomics and routine measurement service
Custom targeted LC‑MS/MS assay setup, routine sample measurement and high‑throughput targeted quantification using isotope‑labelled standards.
Host cell protein (HCP) analysis services
Untargeted and targeted HCP detection and absolute quantification workflows, custom HCP assay development and GMP‑transfer support.
Metaproteomics analysis
Proteome extraction, fractionation, LC‑MS/MS measurement and computational analysis for environmental and complex multi‑organism samples.
Phage and viral analytics
Quantitative proteomics and HCP analytics for phage/viral therapeutics including quality control and stoichiometry determination.
Assay development and validation (custom)
Custom assay development for new host systems, critical targets or regulatory requirements, including validation and GMP‑transfer.
Expertise Areas
- Targeted proteomics and absolute quantification
- Mass spectrometry assay development and validation
- Host cell protein (HCP) identification and quantification
- Clinical proteomics and biomarker discovery/validation
Key Technologies
- High‑resolution LC‑MS/MS (Orbitrap and similar platforms)
- Targeted proteomics (PRM/MRM/SRM and DIA/SWATH approaches)
- QconCAT concatenated heavy‑isotope reference standards
- Stable isotope labelling of proteins (15N, 13C Arg/Lys etc.)