Creative Proteomics


Academic and contract laboratory providing mass spectrometry-based proteomics, metabolomics and glycomics services. Offers end-to-end support from experimental design and sample processing to high-resolution LC-MS/MS acquisition, targeted assay development, enrichment workflows for diverse post-translational modifications (including SUMOylation and methylation), specialized small-molecule analyses, bioinformatics pipelines and documentation suitable for research reporting and submission-ready deliverables.

Industries

Biotechnology
Health Care
Pharmaceutical
Biotechnology Research

Nr. of Employees

medium (51-250)

Creative Proteomics


Products

Organic Acids

LC-MS/MS assay kit for organic acids analysis.

Organic Acids GC-MS Analysis Kit (90 Kinds)

An analysis kit designed for the quantification of 90 kinds of organic acids using GC-MS technology, suitable for samples such as urine and plasma/serum.

CP PolyQuantification

The CP PolyQuantification Customized Absolute Proteins Kit offers tailored reference standards, individually engineered to meet the specific requirements of each project using heavy-labeled proteins for precise and accurate quantification via mass spectrometry.

CP PolyQuantification 270 Human Plasma Kit

Simultaneously quantify up to 270 human proteins from a single plasma sample using MRM-MS technology and stable isotope-labeled peptides for precise, absolute quantification.

CP PolyQuantification 125 Human Plasma Kit

The CP PolyQuantification 125 Human Plasma Kit leverages stable isotope-labeled peptides for precise protein quantification, using advanced MRM-MS technology to measure up to 125 human proteins in a single plasma sample.

CP PolyQuantification 375 Mouse Plasma Kit

The CP PolyQuantification 375 Mouse Plasma Kit allows for the simultaneous quantification of up to 375 mouse proteins from a single plasma sample using MRM-MS technology and stable isotope-labeled peptides.

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Services

Mass spectrometry-based protein identification, quantification, PTM profiling and proteoform analysis provided as project-based laboratory services.

Dedicated workflows for enrichment, LC-MS/MS detection and quantitative analysis of specific PTMs with tailored sample preparation and bioinformatic interpretation.

Proteome-wide site-level detection of endogenous SUMO modifications using alpha-lytic protease digestion to generate diGly remnant peptides, immunoaffinity enrichment of K-ε-GG peptides, LC-MS/MS identification and quantitative analysis options.

Enrichment and mapping of lysine and arginine methylation using methyl-specific immunoaffinity and orthogonal chromatography, with LC-MS/MS identification and quantitative options.

Workflows combining chemical or antibody enrichment, metabolic or probe labeling where applicable, and high-resolution LC-MS/MS for sensitive, site-specific identification and quantification of specific PTMs.

In vivo and in vitro PPI detection and mapping using co-immunoprecipitation/IP-MS, affinity purification, proximity labeling, crosslinking-MS, yeast two-hybrid, pull-downs and orthogonal biophysical assays, with downstream MS identification and analysis.

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Expertise Areas

  • Mass spectrometry-based proteomics (discovery and targeted)
  • Post-translational modification mapping and site localization
  • SUMOylation site mapping and analysis
  • Protein methylation profiling
  • Show More (5)

Key Technologies

  • High-resolution accurate-mass LC-MS/MS
  • Trapped ion mobility and ion-mobility-enabled separations
  • Tandem MS fragmentation modes (ETD, HCD, CID, EThcD)
  • Data-independent and data-dependent acquisition (DIA, DDA)
  • Show More (12)

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