Sapient
Sapient is a biomarker discovery organization specializing in multi-omics services including proteomics, metabolomics, and lipidomics. Their mission is to generate biological insights from every sample to better understand disease and accelerate drug development, leveraging advanced mass spectrometry, AI-driven analysis, and a comprehensive biorepository. They aim to improve health outcomes through innovative technologies, rapid data turnaround, and high-quality, regulated laboratory services.
Industries
Nr. of Employees
small (1-50)
Sapient
1234 Science Park, San Diego, CA 92121
Patents
System and method of utilizing radio bars to tailor coverage options for an insurance policy
US-10102588-B1
View Details
System and method of utilizing radio bars to tailor coverage options for an insurance policy
US-10102588-B1
View DetailsProducts
DynamiQ multi‑omics insights engine (multi‑omics database)
A curated, AI‑ready multi‑omics database and biorepository of longitudinal human biosamples integrating proteomics, metabolomics, lipidomics, cytokines, whole‑genome variants, and harmonized real‑world phenotypic and outcomes data for cohort analytics and biomarker validation.
Targeted Protein Assay Menu (assay catalog)
Searchable catalog of targeted protein assays covering thousands of proteins and PTMs with filters for matrix type, signaling pathways, biological processes, and associated phenotypes to identify assays relevant to specific studies.
DynamiQ multi‑omics insights engine (multi‑omics database)
A curated, AI‑ready multi‑omics database and biorepository of longitudinal human biosamples integrating proteomics, metabolomics, lipidomics, cytokines, whole‑genome variants, and harmonized real‑world phenotypic and outcomes data for cohort analytics and biomarker validation.
Targeted Protein Assay Menu (assay catalog)
Searchable catalog of targeted protein assays covering thousands of proteins and PTMs with filters for matrix type, signaling pathways, biological processes, and associated phenotypes to identify assays relevant to specific studies.
Services
Nontargeted, high‑throughput metabolomics and lipidomics screening using rapid LC‑MS to capture thousands of small molecules per sample with rapid turnaround for large‑scale studies.
Mass spectrometry discovery proteomics with deep proteome coverage and PTM annotation using label‑free DIA and ion mobility approaches, scalable to cover plasma, CSF, saliva, tumor, urine, and tissue samples.
Quantitative mass spectrometry assays for proteins and proteoforms across multiple matrices, with a large searchable assay menu (>12,000 assays) and options for custom assay development.
Ready‑to‑order and customizable targeted panels for specific metabolite and lipid classes (amino acids, fatty acids, diglycerides, FAHFAs, phospholipids, triglycerides, VLCDCAs, etc.) delivered via high‑throughput MS.
Multiplex immunoassay panels and single‑plex custom assays using a sequential immunocomplex capture platform to quantify low‑abundance cytokines, chemokines, and neuroinflammatory markers with attomolar sensitivity and wide dynamic range.
Multi‑scale data analysis including statistical modeling, explainable machine learning, pathway mapping, predictive model development, GWAS mapping, and integration of multi‑omics with clinical and real‑world data to identify and validate biomarkers and targets.
Nontargeted, high‑throughput metabolomics and lipidomics screening using rapid LC‑MS to capture thousands of small molecules per sample with rapid turnaround for large‑scale studies.
Mass spectrometry discovery proteomics with deep proteome coverage and PTM annotation using label‑free DIA and ion mobility approaches, scalable to cover plasma, CSF, saliva, tumor, urine, and tissue samples.
Quantitative mass spectrometry assays for proteins and proteoforms across multiple matrices, with a large searchable assay menu (>12,000 assays) and options for custom assay development.
Ready‑to‑order and customizable targeted panels for specific metabolite and lipid classes (amino acids, fatty acids, diglycerides, FAHFAs, phospholipids, triglycerides, VLCDCAs, etc.) delivered via high‑throughput MS.
Multiplex immunoassay panels and single‑plex custom assays using a sequential immunocomplex capture platform to quantify low‑abundance cytokines, chemokines, and neuroinflammatory markers with attomolar sensitivity and wide dynamic range.
Multi‑scale data analysis including statistical modeling, explainable machine learning, pathway mapping, predictive model development, GWAS mapping, and integration of multi‑omics with clinical and real‑world data to identify and validate biomarkers and targets.
Expertise Areas
- Multi-omics biomarker discovery (proteomics, metabolomics, lipidomics)
- High-throughput mass spectrometry and analytical method development
- Targeted assay development and quantitative proteomics
- High-sensitivity cytokine and chemokine profiling
Key Technologies
- Rapid liquid chromatography–mass spectrometry (rLC‑MS)
- Trapped ion mobility spectrometry
- Label‑free data‑independent acquisition (DIA) proteomics
- Nanoparticle enrichment for low‑abundance proteins
News & Updates
A large-scale metabolomics study using Sapient's next-generation mass spectrometry identified a metabolic aging clock and provided disease insights.
An article on how metabolomics can be used to predict diabetes through machine learning analysis.
A large-scale metabolomics study using Sapient's next-generation mass spectrometry identified a metabolic aging clock and provided disease insights.
A large-scale metabolomics study using Sapient's next-generation mass spectrometry identified a metabolic aging clock and provided disease insights.
An article on how metabolomics can be used to predict diabetes through machine learning analysis.
A large-scale metabolomics study using Sapient's next-generation mass spectrometry identified a metabolic aging clock and provided disease insights.