Anaquant
Anaquant is a specialized Contract Research Organization (CRO) with over 15 years of experience in host cell proteins quantification and identification using mass spectrometry. The company supports pharmaceutical and biotech companies during drug development and bioproduction processes, offering innovative, standardized, and robust analytical solutions to ensure product quality, safety, and efficacy. Anaquant's mission is to bridge the gap between research and routine bioanalysis through its expertise and proprietary technologies.
Industries
Nr. of Employees
small (1-50)
Anaquant
Products
Peptide-based soluble internal calibration bead kit for MS quantification
A hydro-soluble bead product containing a defined mix of non-natural peptides that releases known peptide concentrations into samples to generate internal calibration curves for LC‑MS quantification.
Targeted LC‑MS panel kit for predefined host‑cell protein panels
A targeted LC‑MS assay package and associated peptide standards for the quantification of a predefined panel of critical host‑cell proteins across process samples.
MS data processing and HCP quantification software
Software tools to manage LC‑MS data, extract TOP3 signals, apply internal calibration curves and produce per-protein quantity reports for HCP profiling and comparative studies.
Peptide-based soluble internal calibration bead kit for MS quantification
A hydro-soluble bead product containing a defined mix of non-natural peptides that releases known peptide concentrations into samples to generate internal calibration curves for LC‑MS quantification.
Targeted LC‑MS panel kit for predefined host‑cell protein panels
A targeted LC‑MS assay package and associated peptide standards for the quantification of a predefined panel of critical host‑cell proteins across process samples.
MS data processing and HCP quantification software
Software tools to manage LC‑MS data, extract TOP3 signals, apply internal calibration curves and produce per-protein quantity reports for HCP profiling and comparative studies.
Services
Host‑cell protein (HCP) profiling and quantification
Identification and per-protein quantification of HCPs across harvests, purification intermediates and drug substance using LC‑MS workflows and peptide-based calibration standards.
Targeted panel quantification by LC‑MS (multiplexed protein panels)
Development and delivery of targeted LC‑MS assays to quantify predefined panels of critical proteins (e.g., multi‑dozen HCP panels) using targeted SRM/MRM/PRM approaches and peptide internal standards.
Protein characterization (intact mass, peptide mapping, PTM analysis)
Analytical characterization of therapeutic proteins including intact mass analysis, peptide mapping and targeted post‑translational modification identification.
Drug protein quantification and early PK/PD bioanalysis
Quantification of drug targets, therapeutic proteins and peptides in preclinical matrices including early pharmacokinetic studies, using targeted LC‑MS and enrichment strategies.
Immuno‑precipitation MS workflows for low-abundance analytes
IP‑MS methods to enrich and quantify low-abundance proteins (e.g., monoclonal antibodies) in complex matrices before LC‑MS analysis.
Vaccine antigen identification and multiplex quantification
Differentiation and quantification of homologous antigens in polyvalent vaccine formulations using signature-peptide LC‑MS assays.
Host‑cell protein (HCP) profiling and quantification
Identification and per-protein quantification of HCPs across harvests, purification intermediates and drug substance using LC‑MS workflows and peptide-based calibration standards.
Targeted panel quantification by LC‑MS (multiplexed protein panels)
Development and delivery of targeted LC‑MS assays to quantify predefined panels of critical proteins (e.g., multi‑dozen HCP panels) using targeted SRM/MRM/PRM approaches and peptide internal standards.
Protein characterization (intact mass, peptide mapping, PTM analysis)
Analytical characterization of therapeutic proteins including intact mass analysis, peptide mapping and targeted post‑translational modification identification.
Drug protein quantification and early PK/PD bioanalysis
Quantification of drug targets, therapeutic proteins and peptides in preclinical matrices including early pharmacokinetic studies, using targeted LC‑MS and enrichment strategies.
Immuno‑precipitation MS workflows for low-abundance analytes
IP‑MS methods to enrich and quantify low-abundance proteins (e.g., monoclonal antibodies) in complex matrices before LC‑MS analysis.
Vaccine antigen identification and multiplex quantification
Differentiation and quantification of homologous antigens in polyvalent vaccine formulations using signature-peptide LC‑MS assays.
Expertise Areas
- Host-cell protein (HCP) analysis and quantification
- Mass spectrometry-based bioanalysis (LC‑MS/MS)
- Targeted proteomics assay development (SRM/MRM/PRM)
- Protein characterization (intact mass, peptide mapping, PTM analysis)
Key Technologies
- Liquid chromatography–mass spectrometry (LC‑MS/MS)
- Targeted MS: SRM / MRM / PRM
- Data‑dependent and data‑independent acquisition (DDA / DIA)
- Peptide-based internal calibration standards (soluble bead format)