Synthelis
Synthelis Biotech specializes in cell-free systems and bioluminescence applications, providing innovative solutions for accelerating biological research and development. Since 2011, they have been supporting scientists and industry worldwide with proprietary cell-free expression technology and custom protein expression in E. coli. They are pioneers in next-generation bioluminescence, enabling advances in detection, diagnostics, and imaging. Collaborating with pharmaceutical, biomedical, biotechnological, and academic laboratories, Synthelis fosters innovation by offering concrete solutions to scientific and ethical challenges. The company is also actively involved in developing acellular production systems for amyloid fibrils, biomedicines, and structural biology, contributing to drug discovery, bioproduction, and understanding disease mechanisms.
Industries
Nr. of Employees
small (1-50)
Synthelis
5, avenue du Grand Sablon, 38700 La Tronche, France
Patents
Formation of proteoliposomes containing membrane proteins by means of an acellular protein synthesis system
US-9206456-B2
View Details
Formation of proteoliposomes containing membrane proteins by means of an acellular protein synthesis system
US-9206456-B2
View DetailsProducts
Cell-free expression lysates
Prepared cell lysate reagents for in vitro protein synthesis workflows (lyophilized and liquid formats).
Cell-free expression kits
Ready-to-use kits to perform cell-free protein expression workflows for screening, education and small-scale production.
Bioluminescent assay substrates
Reagent substrates for bioluminescence detection used in assays and imaging.
Catalog recombinant proteins
Pre-produced proteins listed in a public catalogue for purchase and research use.
Cell-free expression lysates
Prepared cell lysate reagents for in vitro protein synthesis workflows (lyophilized and liquid formats).
Cell-free expression kits
Ready-to-use kits to perform cell-free protein expression workflows for screening, education and small-scale production.
Bioluminescent assay substrates
Reagent substrates for bioluminescence detection used in assays and imaging.
Catalog recombinant proteins
Pre-produced proteins listed in a public catalogue for purchase and research use.
Services
Contract synthesis of proteins using cell-free expression systems for research, screening and development projects.
Contract production of recombinant proteins using E. coli expression systems for R&D and product development.
Analytical and validation services for proteins, including quantification, activity assays and structural characterization.
Production of proteins labeled with stable isotopes and fluorinated amino acids for solid-state and solution NMR, and other structural analyses.
Preparation and workflow optimization of protein samples and assemblies produced by cell-free methods for compatibility with cryo-EM, solid-state NMR and X‑ray crystallography.
Contract synthesis of proteins using cell-free expression systems for research, screening and development projects.
Contract production of recombinant proteins using E. coli expression systems for R&D and product development.
Analytical and validation services for proteins, including quantification, activity assays and structural characterization.
Production of proteins labeled with stable isotopes and fluorinated amino acids for solid-state and solution NMR, and other structural analyses.
Preparation and workflow optimization of protein samples and assemblies produced by cell-free methods for compatibility with cryo-EM, solid-state NMR and X‑ray crystallography.
Expertise Areas
- Cell-free protein synthesis (CFPS) for research and production
- Recombinant protein production in microbial hosts
- Membrane protein expression and proteoliposome preparation
- Structural biology sample preparation (NMR, cryo-EM, X-ray)
Key Technologies
- Cell-free protein synthesis (CFPS)
- E. coli-based cell lysate expression
- Wheat germ and eukaryotic CFPS systems
- Proteoliposome assembly
News & Updates
Synthelis est très fière d’être l’un des lauréats de l’initiative européenne Sanofi iDEA-TECH Awards
Synthelis a été récompensée dans la catégorie « Processes in Chemistry, Manufacturing, and Control » pour sa technologie acellulaire innovante.
Vincent Poher, spécialiste du diagnostic in vitro, a récemment acquis Synthelis, permettant de nouvelles opportunités et innovations.
Récompense pour l'innovation dans les processus de chimie, fabrication et contrôle.
Synthelis est très fière d’être l’un des lauréats de l’initiative européenne Sanofi iDEA-TECH Awards
Synthelis a été récompensée dans la catégorie « Processes in Chemistry, Manufacturing, and Control » pour sa technologie acellulaire innovante.
Vincent Poher, spécialiste du diagnostic in vitro, a récemment acquis Synthelis, permettant de nouvelles opportunités et innovations.
Récompense pour l'innovation dans les processus de chimie, fabrication et contrôle.