StemImmune


StemImmune LLC is a biotechnology company dedicated to developing and manufacturing high-quality cytokines, recombinant proteins, mediums, and kits for lab and preclinical research. Their products are widely used in stem cell and immune cell culture, with ongoing efforts to translate these products into human disease treatments, especially in tumor immunotherapy. The company also offers custom services including recombinant protein production and cell culture services. Their mission is to provide the best products and solutions, aiming to be a trusted supplier in the life sciences and cell therapy markets.

Industries

biopharma
biotechnology
manufacturing

Nr. of Employees

small (1-50)

StemImmune

Livermore, California, United States, North America


Products

Recombinant human HGF

Lyophilized recombinant human hepatocyte growth factor produced in human cell expression systems; supplied with activity assay data, Certificate of Analysis, datasheet and safety data sheet.

Recombinant human BMP-2

Lyophilized recombinant human bone morphogenetic protein-2 produced in human cells with activity measured by alkaline phosphatase induction; COA and SDS available.

Antibody-conjugated magnetic nanoparticles for CD3/CD28 T cell activation

Magnetic particles conjugated with antibodies targeting T cell activation receptors, supplied as aqueous suspension with protocols for washing, magnetic separation and culture use.

CD293 medium (chemically-defined, serum-free) for suspension culture

Chemically-defined, serum-free medium optimized for high-density suspension culture of HEK293 cells; documentation (COA, datasheet) provided and manufactured under cGMP standards.

Sequence-specific protease for affinity tag removal (HRV 3C)

Purified sequence-specific protease for removal of affinity tags from fusion proteins, provided with reaction buffer, unit definition and guidance for removal of the protease after cleavage.

Recombinant human IGF-1 (E. coli-derived)

Lyophilized recombinant human IGF-1 produced in E. coli with specified purity, endotoxin limits and an activity assay measuring stimulation of fibroblast proliferation; supplied with COA, datasheet and SDS.

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Services

Custom recombinant protein production

Contract production of recombinant proteins in bacterial or mammalian cells, including upstream expression, downstream purification and formulation into lyophilized or solution formats.

Cell line development

Services to develop and optimize cell lines for recombinant protein expression and scalable preclinical workflows.

Protein purification and enzymatic cleavage support

Purification workflows and support for enzymatic removal of affinity tags using sequence-specific proteases, including protocols for protease use and removal.

Immune cell culture and expansion services

Support for differentiation, activation and expansion of immune cell types (T cells, NK cells, DCs, CIK) and related assay development and reagent supply.

Supply of recombinant cytokines and growth factors

Commercial supply of a broad panel of recombinant cytokines, growth factors and related reagents with stated purity, endotoxin limits and activity data for research and preclinical applications.

Expertise Areas

  • Recombinant protein production in mammalian, CHO and bacterial systems
  • Formulation and lyophilization of biologic reagents
  • Chemically-defined, serum-free media formulation for suspension culture
  • Immune cell culture, activation and expansion protocols
  • Show More (4)

Key Technologies

  • Mammalian cell expression (HEK293, human-derived)
  • CHO and E. coli expression systems
  • Lyophilization and sterile formulation
  • Low-endotoxin purification and endotoxin testing
  • Show More (6)

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