ProteoNic BV
ProteoNic is a vector technology company specializing in premium vector technology to enhance protein production, viral vector titers, and gene expression in various platforms including mammalian cells, yeast, and fungi. The company licenses its innovative technologies to pharmaceutical, biotech, and CDMO clients worldwide, aiming to improve productivity and cost-effectiveness in biologics and gene therapy manufacturing.
Industries
Nr. of Employees
small (1-50)
ProteoNic BV
Products
Premium vector technology for mammalian expression
Validated vector elements and vector backbones to increase transcription, mRNA stability and translation efficiency for enhanced recombinant protein production in CHO and HEK systems; offered in ready vector and element formats for integration into existing vectors.
Yeast/fungal expression vector system
Yeast-optimized vector elements designed to improve transcription and translation in Pichia and other yeast/fungal hosts, validated for fed-batch scalability and reproducibility across many proteins.
Viral vector performance modules (lentivirus and AAV)
Vector element sets to increase lentiviral particle titers and to boost AAV transgene/payload expression when integrated into existing viral production constructs.
Glyco-engineering construct for increased sialylation
Expression construct delivering a modified sialyltransferase to CHO cell lines to obtain human-type 6-sialylation of N-glycans and improve product quality.
Premium vector technology for mammalian expression
Validated vector elements and vector backbones to increase transcription, mRNA stability and translation efficiency for enhanced recombinant protein production in CHO and HEK systems; offered in ready vector and element formats for integration into existing vectors.
Yeast/fungal expression vector system
Yeast-optimized vector elements designed to improve transcription and translation in Pichia and other yeast/fungal hosts, validated for fed-batch scalability and reproducibility across many proteins.
Viral vector performance modules (lentivirus and AAV)
Vector element sets to increase lentiviral particle titers and to boost AAV transgene/payload expression when integrated into existing viral production constructs.
Glyco-engineering construct for increased sialylation
Expression construct delivering a modified sialyltransferase to CHO cell lines to obtain human-type 6-sialylation of N-glycans and improve product quality.
Services
Licensing and technology transfer
Evaluation research licenses and commercial licensing for vector elements and validated vector backbones with technology transfer support and flexible commercial terms (platform or per-product models).
Co-development and early access programs
Limited-partner early access or co-development programs for integration of advanced vector elements into partner workflows to boost viral vector titers or transgene expression.
Vector design and technical support services
Design of expression vectors, supply of transfection-ready DNA, provision of validated protocols, and on-request customization of vector variants with expert scientific support.
Glycosylation analytics and optimization consultancy
Analytical services and consultancy to implement glyco-engineering constructs and optimize culture/media conditions to achieve human-type sialylation of expressed proteins.
Licensing and technology transfer
Evaluation research licenses and commercial licensing for vector elements and validated vector backbones with technology transfer support and flexible commercial terms (platform or per-product models).
Co-development and early access programs
Limited-partner early access or co-development programs for integration of advanced vector elements into partner workflows to boost viral vector titers or transgene expression.
Vector design and technical support services
Design of expression vectors, supply of transfection-ready DNA, provision of validated protocols, and on-request customization of vector variants with expert scientific support.
Glycosylation analytics and optimization consultancy
Analytical services and consultancy to implement glyco-engineering constructs and optimize culture/media conditions to achieve human-type sialylation of expressed proteins.
Expertise Areas
- Vector engineering for enhanced gene expression
- Cell line development and stable expression systems
- Viral vector manufacturing optimization (LV and AAV)
- Yeast and fungal expression optimization
Key Technologies
- Dual-promoter vector architectures
- mRNA stability and translation enhancers (synthetic intron, ribosome affinity optimization)
- Transposon-mediated targeted integration
- Glyco-engineering for sialylation