ATUM
Integrated biotechnology company offering gene design and synthesis, protein engineering and expression, cell line development, expression host platforms, reagent supply, and analytical services. Provides transposase-based genome integration, computational vector design, gRNA design and CRISPR cloning workflows, high-throughput expression and cloning processes, and LIMS and machine-learning tools to move projects from sequence design through research cell bank and GMP-ready processes.
Industries
Nr. of Employees
medium (51-250)
Products
Expression vectors for bacterial, mammalian and yeast hosts
Catalog vectors with a range of promoters, selection markers and elements for transient or stable expression and multi‑ORF constructs.
Transposon integration reagents and integration platform
Reagents and support to apply a transposase-mediated integration workflow for generating stable pools and clonal cell lines.
Pre-characterized transient expression host for discovery-scale production
CHO-derived transient expression host intended to produce discovery material with critical quality attributes aligned to CHO manufacturing hosts.
Characterized Pichia pastoris strains
Catalog yeast strains with genomic characterization and culture/induction protocols for fermentation and expression experiments.
Affinity tag proteases and validated cleavage protocols
Affinity-purified proteases and validated protocols for removal of fusion tags from recombinant proteins.
Pre-linearized CRISPR vectors and type IIS cloning kit
Pre-linearized CRISPR vector DNA and associated type IIS-based cloning reagents designed to enable rapid insertion of gRNA sequences via a short room-temperature cloning reaction.
Expression vectors for bacterial, mammalian and yeast hosts
Catalog vectors with a range of promoters, selection markers and elements for transient or stable expression and multi‑ORF constructs.
Transposon integration reagents and integration platform
Reagents and support to apply a transposase-mediated integration workflow for generating stable pools and clonal cell lines.
Pre-characterized transient expression host for discovery-scale production
CHO-derived transient expression host intended to produce discovery material with critical quality attributes aligned to CHO manufacturing hosts.
Characterized Pichia pastoris strains
Catalog yeast strains with genomic characterization and culture/induction protocols for fermentation and expression experiments.
Affinity tag proteases and validated cleavage protocols
Affinity-purified proteases and validated protocols for removal of fusion tags from recombinant proteins.
Pre-linearized CRISPR vectors and type IIS cloning kit
Pre-linearized CRISPR vector DNA and associated type IIS-based cloning reagents designed to enable rapid insertion of gRNA sequences via a short room-temperature cloning reaction.
Services
Gene design and synthesis services
Design and synthesis of codon-optimized genes and constructs for multiple expression hosts, with support for vector cloning and sequence optimization.
Cell line development and master cell banking
Stable pool generation, clone isolation, stability testing and research/master cell bank creation using transposase-based integration.
Protein expression and purification services
Transient and stable mammalian protein production workflows for discovery to preclinical quantities, with preparative purification and analytics.
Antibody engineering and analytical services
Antibody sequence optimization, developability assessment, and binding/kinetic assay development using SPR and BLI.
CRISPR construct design, gRNA design and cloning services
Web-based gRNA design combined with cloning services to deliver ready-to-transfect CRISPR vectors (including dual‑gRNA nickase constructs); includes guidance on primer design, avoidance of type IIS recognition sites, and sequencing-based screening workflows.
Reagent and enzyme supply
Catalog supply of proteases for tag cleavage and other reagents to support protein workflows.
Gene design and synthesis services
Design and synthesis of codon-optimized genes and constructs for multiple expression hosts, with support for vector cloning and sequence optimization.
Cell line development and master cell banking
Stable pool generation, clone isolation, stability testing and research/master cell bank creation using transposase-based integration.
Protein expression and purification services
Transient and stable mammalian protein production workflows for discovery to preclinical quantities, with preparative purification and analytics.
Antibody engineering and analytical services
Antibody sequence optimization, developability assessment, and binding/kinetic assay development using SPR and BLI.
CRISPR construct design, gRNA design and cloning services
Web-based gRNA design combined with cloning services to deliver ready-to-transfect CRISPR vectors (including dual‑gRNA nickase constructs); includes guidance on primer design, avoidance of type IIS recognition sites, and sequencing-based screening workflows.
Reagent and enzyme supply
Catalog supply of proteases for tag cleavage and other reagents to support protein workflows.
Expertise Areas
- Gene design and synthetic biology
- Cell line development and clonal selection
- Protein expression and purification
- Antibody engineering and developability assessment
Key Technologies
- Transposase-mediated genome integration
- Computational vector and promoter engineering
- Transient and stable mammalian expression
- gRNA specificity scoring algorithms