DNA2.0
ATUM is a biotechnology contract research and development organization (CRDO) based in Newark, California. The company provides integrated gene, protein and cell-line engineering services that combine design-of-experiment workflows, empirical testing and machine learning to support gene design and synthesis, protein engineering, analytical development, cell line development, and manufacturing support for research through preclinical/CMC activities.
Industries
Nr. of Employees
medium (51-250)
DNA2.0
Products
Expression vector catalog (bacterial, mammalian, yeast)
Preconfigured expression vectors providing different promoters, secretion signals, selection markers and solubility/affinity tags for rapid testing and expression.
gRNA design and CRISPR support tools
Web-accessible guide RNA design utilities and CRISPR vector offerings to support genome editing experiments and vector ordering.
Gene design and sequence management software
Graphical gene-design and sequence management tools for in silico cloning, back-translation, codon optimization and construct annotation.
Expression vector catalog (bacterial, mammalian, yeast)
Preconfigured expression vectors providing different promoters, secretion signals, selection markers and solubility/affinity tags for rapid testing and expression.
gRNA design and CRISPR support tools
Web-accessible guide RNA design utilities and CRISPR vector offerings to support genome editing experiments and vector ordering.
Gene design and sequence management software
Graphical gene-design and sequence management tools for in silico cloning, back-translation, codon optimization and construct annotation.
Services
Gene design and synthesis services
Sequence optimization and synthesis of genes and DNA fragments for research and development applications.
Antibody development and engineering
Hybridoma sequencing, sequence-based humanization, affinity maturation and developability testing for monoclonal antibodies.
Cell line development and licensing
Stable cell line generation, stable pool selection, clone isolation, master cell banking and licensing of integration and vector platform technologies to support in-house workflows.
Protein expression and analytical services
Transient and stable protein production, purification, and a portfolio of analytical assays for identity, purity, glycosylation and stability.
Multidimensional biological engineering services
Optimization platform combining DoE, empirical measurement and machine learning to optimize genes, vectors, proteins and antibodies for improved expression and developability.
Technology licensing and distribution
Licensing and distribution partnerships to deploy integration platforms, expression vectors and related tools to commercial partners and distributors.
Gene design and synthesis services
Sequence optimization and synthesis of genes and DNA fragments for research and development applications.
Antibody development and engineering
Hybridoma sequencing, sequence-based humanization, affinity maturation and developability testing for monoclonal antibodies.
Cell line development and licensing
Stable cell line generation, stable pool selection, clone isolation, master cell banking and licensing of integration and vector platform technologies to support in-house workflows.
Protein expression and analytical services
Transient and stable protein production, purification, and a portfolio of analytical assays for identity, purity, glycosylation and stability.
Multidimensional biological engineering services
Optimization platform combining DoE, empirical measurement and machine learning to optimize genes, vectors, proteins and antibodies for improved expression and developability.
Technology licensing and distribution
Licensing and distribution partnerships to deploy integration platforms, expression vectors and related tools to commercial partners and distributors.
Expertise Areas
- Gene design and codon optimization
- Synthetic gene synthesis
- Protein engineering and directed evolution
- Antibody engineering and humanization
Key Technologies
- Empirically-trained codon optimization algorithms
- Transposon/transposase-mediated genomic integration
- Machine learning combined with Design of Experiments
- Gene synthesis and DNA fragment production