Mirimus
Provider of preclinical research and diagnostic services including custom genetically engineered rodent models, 2D/3D cell model development, RNA interference (RNAi) design and delivery, CRISPR gene editing and functional screening, molecular diagnostic assay development, and preclinical drug discovery support (screening, PK/PD, formulation, and toxicity). Services emphasize customizable model generation, assay development and validation, high-throughput and automated workflows, and scalable diagnostic testing.
Industries
Nr. of Employees
small (1-50)
Mirimus
Brooklyn, New York, United States, North America
Products
Custom Genetically-Engineered Mouse Models with Reverse Gene Silencing
Production of genetically-engineered mouse models that allow for reverse gene silencing to support medical research.
Biosensors for Real-Time Infectious Disease Detection
Biosensors that detect trace levels of infectious disease agents in real-time through electrical signals generated by bioprobes coupled to field-effect transistors.
Custom Genetically-Engineered Mouse Models with Reverse Gene Silencing
Production of genetically-engineered mouse models that allow for reverse gene silencing to support medical research.
Biosensors for Real-Time Infectious Disease Detection
Biosensors that detect trace levels of infectious disease agents in real-time through electrical signals generated by bioprobes coupled to field-effect transistors.
Services
Custom animal model generation
End-to-end design and production of transgenic, knock-in/knock-out, inducible, humanized, reporter, orthotopic, syngeneic, and PDX models in mice and rats.
2D/3D in vitro model development and high-throughput screening
Development of 2D cell lines and 3D organoid models plus automated screening workflows for efficacy, toxicity, and mechanism-of-action studies.
RNAi services (design, delivery, validation)
Design and synthesis of siRNA/shRNA/artificial miRNA triggers, target validation and optimization, development of LNP formulations and viral vector delivery, and preclinical validation in vitro and in vivo.
CRISPR services and functional screening
Design and validation of CRISPR guides, targeted editing (knock-out/knock-in), CRISPR screening for target discovery, and functional confirmation assays.
Molecular diagnostic testing and LDT development
Molecular diagnostic assay development and laboratory testing services, including PCR, multiplex respiratory/STD panels, saliva-based testing, LAMP assays, and MPOX PCR testing with scalable throughput.
Formulation, PK/PD and safety support
Formulation development for small molecules, biologics, and nucleic acid therapeutics (including LNP and viral vector considerations), plus ADME, PK/PD studies, modeling and toxicity testing to inform candidate selection.
Custom animal model generation
End-to-end design and production of transgenic, knock-in/knock-out, inducible, humanized, reporter, orthotopic, syngeneic, and PDX models in mice and rats.
2D/3D in vitro model development and high-throughput screening
Development of 2D cell lines and 3D organoid models plus automated screening workflows for efficacy, toxicity, and mechanism-of-action studies.
RNAi services (design, delivery, validation)
Design and synthesis of siRNA/shRNA/artificial miRNA triggers, target validation and optimization, development of LNP formulations and viral vector delivery, and preclinical validation in vitro and in vivo.
CRISPR services and functional screening
Design and validation of CRISPR guides, targeted editing (knock-out/knock-in), CRISPR screening for target discovery, and functional confirmation assays.
Molecular diagnostic testing and LDT development
Molecular diagnostic assay development and laboratory testing services, including PCR, multiplex respiratory/STD panels, saliva-based testing, LAMP assays, and MPOX PCR testing with scalable throughput.
Formulation, PK/PD and safety support
Formulation development for small molecules, biologics, and nucleic acid therapeutics (including LNP and viral vector considerations), plus ADME, PK/PD studies, modeling and toxicity testing to inform candidate selection.
Expertise Areas
- Genetic engineering and custom animal model development
- Inducible and reversible gene-control systems
- RNA interference design, delivery and validation
- CRISPR-based gene editing and functional screening
Key Technologies
- CRISPR gene editing
- RNA interference (siRNA, shRNA, artificial miRNA)
- Lipid nanoparticle (LNP) formulation
- Viral vector delivery systems