KSQ Therapeutics


KSQ Therapeutics is dedicated to curing human diseases by leveraging gene-editing and CRISPR/Cas9 technology to discover and develop transformative medicines. Their mission is to drive cures in hard-to-treat diseases, focusing initially on cancer, with a pipeline of innovative therapeutics including eTIL® programs and a platform called CRISPRomics®. The company aims to overcome significant challenges in solid tumor treatment and is committed to scientific excellence, collaboration, and patient-focused innovation.

Industries

biopharma
biotechnology
pharmaceutical
therapeutics

Nr. of Employees

medium (51-250)

KSQ Therapeutics

4 Maguire Road, Lexington, MA 02421


Patents

Gene-regulating compositions and methods for improved immunotherapy

US-12280111-B2

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Guide RNA combinations and methods of use

US-12188045-B2

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Gene-regulating compositions and methods for improved immunotherapy

US-12123021-B2

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Gene-regulating compositions and methods for improved immunotherapy

US-12084682-B2

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Methods for measuring and improving CRISPR reagent function

US-11946163-B2

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Methods for screening for cancer targets

US-11912987-B2

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Products

Engineered tumor-infiltrating lymphocyte (eTIL) therapeutic candidates

Autologous engineered T cell therapy candidates generated by editing patient-derived tumor-infiltrating lymphocytes to enhance tumor infiltration and anti-tumor activity for solid tumor indications.


Services

Partnering with pharmaceutical companies and research organizations to co-develop and commercialize cell therapy programs and therapeutic candidates.

Platform-driven discovery of therapeutic targets via genome-wide functional screens and preclinical validation to support therapeutic candidate creation.

Expertise Areas

  • Functional genomic target discovery
  • Cell therapy engineering and development
  • Translational immunology and immune monitoring
  • Preclinical in vivo efficacy testing
  • Show More (4)

Key Technologies

  • CRISPR/Cas9 gene editing
  • Genome-wide CRISPR screening
  • Tumor-infiltrating lymphocyte (TIL) engineering
  • Engineered T cell therapies
  • Show More (4)

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