Ingenious Targeting Laboratory
U.S.-based contract laboratory that designs and delivers genetically engineered rodent and rabbit models for research. Services include sequence-informed allele design, targeted gene modification (homologous recombination and CRISPR), molecular quality control and germline verification, cohort expansion and colony management, and post-delivery technical support. The organization reports >2,800 generated models, >800 publications, AAALAC-accredited animal facilities, and a germline transmission guarantee for delivered projects.
Industries
Nr. of Employees
medium (51-250)
Ingenious Targeting Laboratory
Services
End-to-end project delivery from consultation and allele design through targeting, founder generation, germline verification, and delivery of germline-confirmed F1 heterozygotes.
Structured breeding programs and speed expansion to produce experimental cohorts with calculated genotype ratios and timelines for multi-site reproducibility.
Live, maintained catalog strains available for rapid shipment, including knockout, conditional, humanized, immunodeficient, and disease models.
PCR genotyping, Southern blot confirmation, copy-number analysis, and expression assays provided as stand-alone services or integrated with model generation.
Sperm and embryo cryopreservation for colony backup and embryo transfer-based rederivation to achieve specific-pathogen-free status.
Ongoing colony maintenance, breeding scheme execution, health monitoring, and shipment of maintained lines or cohorts.
End-to-end project delivery from consultation and allele design through targeting, founder generation, germline verification, and delivery of germline-confirmed F1 heterozygotes.
Structured breeding programs and speed expansion to produce experimental cohorts with calculated genotype ratios and timelines for multi-site reproducibility.
Live, maintained catalog strains available for rapid shipment, including knockout, conditional, humanized, immunodeficient, and disease models.
PCR genotyping, Southern blot confirmation, copy-number analysis, and expression assays provided as stand-alone services or integrated with model generation.
Sperm and embryo cryopreservation for colony backup and embryo transfer-based rederivation to achieve specific-pathogen-free status.
Ongoing colony maintenance, breeding scheme execution, health monitoring, and shipment of maintained lines or cohorts.
Expertise Areas
- Genetically engineered animal model generation
- Allele design and targeting construct development
- Conditional and inducible genetics
- Tissue-specific knockout strategy and Cre driver selection
Key Technologies
- Homologous recombination targeting
- CRISPR/Cas genome editing
- Cre-Lox recombination
- Flp-FRT recombination
News & Updates
Publication reporting research supported by generated models.
Publication reporting research supported by generated models.
Publication reporting research supported by generated models.
Reported delivery of over 2,800 genetically engineered mouse models since 1998.
Reported contribution to over 800 peer-reviewed publications across major journals.
Provider-applied guarantee policy for germline transmission on model generation projects.
Publication reporting research supported by generated models.
Publication reporting research supported by generated models.
Publication reporting research supported by generated models.
Reported delivery of over 2,800 genetically engineered mouse models since 1998.
Reported contribution to over 800 peer-reviewed publications across major journals.
Provider-applied guarantee policy for germline transmission on model generation projects.