Large Molecule Drugs
Technical Challenges
Thermal sensitivity and cold-chain dependence limit field distribution and prolonged storage.
Complex and time-consuming manufacturing hampers rapid scale-up for emergent military threats.
Delivery barriers — vascular access, mucosal/microenvironmental barriers, and need for field-friendly administration.
Immunogenicity, off-target effects, and safety monitoring in polytrauma or immunocompromised Warfighters.
Regulatory and quality-assurance constraints for accelerated deployment in austere settings.
Emerging Opportunities
Room-temperature stable formulations and compact cold-chain alternatives for prolonged storage.
Rapid, deployable manufacturing platforms (portable bioreactors, cell-free synthesis) for surge production.
Field-adapted delivery systems (autoinjectors, inhaled/aerosolized, microneedle patches) compatible with prolonged care.
Companion diagnostics and decision-support tools to match biologic therapy to pathogen or host phenotype.
Standardized bridging pathways for emergency use and transition from research to operational use.
Current and Emerging Technologies in Large Molecule Drugs
Recombinant expression and cell-free synthesis
Monoclonal antibody and engineered biologic platforms
Nucleic-acid therapeutics and delivery systems
Stabilization and formulation innovations
Point-of-care diagnostics and companion assays
Importance to Military Medicine
Combat casualty care and toxin neutralization
Prolonged and distributed care
Infectious disease and biodefense readiness
Force readiness and recovery
Alignment with the MTEC Mission
Dual-Use (Military + Civilian) Applications
Explore MTEC Members with Large Molecule Drugs Capabilities
103 Members with Large Molecule Drugs capabilities.
The University of Texas System is a leading public university system in the United States, dedicated to improving lives through education, health care, and research. With over 256,000 students enrolled across 14 institutions, the UT System is committed to providing affordable access to higher education and producing a skilled workforce to drive Texas's economy.
Georgia Southern University is a vibrant institution with over 26,100 students across three campuses in Statesboro, Savannah, and Hinesville. The university offers 132 degree programs at the associate, bachelor’s, master’s, and doctorate levels, emphasizing student success, community impact, and research excellence. With a commitment to inclusivity and engagement, Georgia Southern fosters a supportive environment for diverse learners, including military-affiliated and adult students. The university is dedicated to transforming lives through education and community engagement, aligning its programs with regional needs. Additionally, Georgia Southern provides accelerated pathways for students to fast-track their master's degrees, enhancing educational opportunities. The university also emphasizes career readiness and public impact research, preparing students for successful careers and contributing to community development.
STAT Therapeutics is focused on developing a drug- device combination for easy, rapid administration of intramuscular, life-saving medications by users in any setting, aiming to improve access and usability for acute emergency treatments such as pain, anaphylaxis, and seizures.
Armata Pharmaceuticals, Inc. is a clinical-stage biotechnology company dedicated to developing pathogen-specific bacteriophage therapeutics to combat antibiotic-resistant and difficult-to-treat bacterial infections. With a focus on addressing the global antibiotic resistance crisis, Armata leverages its proprietary bacteriophage-based technology to develop high-impact, best-in-class phage therapeutics. The company operates from a 56,000 square foot facility in Los Angeles, California, equipped for phage product development from bench to clinic. Armata's team of microbiologists and scientists work on discovering natural phages and enhancing them through synthetic biology and engineering to create tailored drug products for clinical trials.
The University of Texas at San Antonio (UTSA) is dedicated to the advancement of knowledge through research, teaching, and community engagement. As a premier public research university, UTSA embraces multicultural traditions and serves as a catalyst for socioeconomic development, providing access to educational excellence and preparing citizen leaders for the global environment.
Auburn University Research & Economic Development is dedicated to advancing research and economic growth through a collaborative effort among its various colleges and departments. The organization focuses on fostering innovation, supporting faculty and student research, and facilitating partnerships with industry and government to address societal challenges and enhance the quality of life. Recent initiatives include the launch of the Team Science Series to promote interdisciplinary collaboration and the development of the Gulf Coast Engineering Research Station to address coastal environmental challenges.
The Institute for Integrative & Innovative Research (I³R) at the University of Arkansas is dedicated to pioneering solutions to wicked problems and societal challenges through convergence research. With a mission to advance research excellence and stimulate economic development, I³R focuses on deploying innovations at scale through collaboration across various sectors, including academia, industry, and government.
UTMB is dedicated to supporting research, education, and scholarly endeavors, with a focus on creating the future of healthcare through innovative research and community engagement.
Action Medical Technologies is a pharmaceutical and medical device company focused on developing innovative solutions that integrate medications with advanced devices and injector systems to improve patient outcomes, particularly in austere prehospital environments.
Vindhya Data Science is a women-owned small business headquartered in North Carolina, USA, with a presence in RTP and Boston. We specialize in bioinformatics, genomics, artificial intelligence, and data engineering, cheminformatics, evidence-based medicine, epidemiology and related disciplines. Vindhya partners with federal government agencies, leading academic medical centers, and pharma/biotech organizations to transform large datasets into informed decisions using advanced data science technologies. With over 100 years of combined experience, 150+ publications, and 73+ successful projects, Vindhya is committed to delivering impactful solutions in the life sciences sector.
Revolution Biomanufacturing Inc. (RBIx) is expanding beyond traditional CDMO Process/Analytical Development and Manufacturing services to pioneer distributed molecular manufacturing. A new class of digital biomanufacturing that enables the autonomous design, manufacture, quality verification, and deployment of Nucleic Acid therapeutics and molecular diagnostics at the point of need. By integrating AI-driven sequence optimization, enzymatic nucleic acid synthesis, Nanoparticle design and manufacturing (LNP & EV), closed-loop quality control, and field-deployable manufacturing platforms, RBIx is creating adaptive biological infrastructure capable of responding to emerging diseases, national security threats, and personalized medicine with unprecedented speed and flexibility.
The University of Chicago is a prestigious urban research university committed to rigorous inquiry and intellectual freedom. Founded in 1890, it has produced numerous Nobel laureates and is known for its transformative education and groundbreaking research across various fields. The university fosters an inclusive and diverse learning environment, encouraging participation from all community members.
Memsel is a biotechnology research and development company dedicated to enhancing health and combatting infections through advanced phage therapies and targeted delivery systems. The company aims to transform healthcare solutions across human, animal, and plant domains, addressing critical health challenges and antibiotic resistance.
Boston University is a major research institution committed to leading breakthroughs across various disciplines. The Office of Research supports and advances research excellence, fostering collaboration among researchers, industry partners, and government leaders to address significant societal challenges.
Baylor University is a preeminent Christian research university committed to addressing the world's most meaningful challenges through top-tier research and scholarship. Recognized as an R1 research institution, Baylor focuses on infusing its distinct Christian mission into its research initiatives, fostering a commitment to excellence and innovation.
Evimero is an interdisciplinary company focused on understanding the interactions between microorganisms and human health, agriculture, and the environment, utilizing Systems Biology and AI/ML. Evimero applies molecular principles to infectious disease and microbiome science to improve health outcomes and environmental sustainability through targeted interventions in dysbiotic microbiomes and in people with infectious disorders. Evimero has an infectious disease product pipeline including both prophylactic and diagnostic assets against common causes of Travelers' Diarrhea, including a unique approach to preventing infection with human Norovirus, enterotoxigenic E. coli (ETEC) and others. Evimero's pipeline of drugs targeting human and animal microbiomes includes early-stage assets aimed at generalized microbiome-driven inflammation and gut leak, and specific disease-targeted disorders including Parkinson Disease and Inflammatory Bowel Diseases. Evimero's platform also makes possible a suite of point-of-care diagnostics that can be used for patient cohorting (infectious diseases), risk stratification, and ultimately informing therapeutic decision-making. The nature of Evimero's platform assures a steady stream of novel assets targeting both infectious diseases and chronic disorders with roots in microbiome dysfunction.
Kane Biotech is a Canadian-based biotechnology company focused on the research, development, and commercialization of products that prevent and remove microbial biofilms. Established in 2001, the company aims to improve human and animal welfare through innovative solutions to biofilm-related challenges and antimicrobial resistance. With a strong portfolio of 54 patents and patents pending, Kane Biotech is recognized as a leader in biofilm research and technology, and is listed on the TSX Venture Exchange under the symbol 'KNE' and on the OTC Markets under the symbol 'KNBIF'.
Purgo Scientific is a medical device company dedicated to developing effective solutions for the biofilm infections crisis in orthopedic surgery. Their mission is to provide a locally targeted sustained delivery device that ensures the right therapy is delivered to the right place for the right duration, ultimately improving patient outcomes and reducing the impact of surgical site infections.
Limax Biosciences is dedicated to revolutionizing tissue healing through innovative biomaterials inspired by the natural slime of slugs. Their hydrogels provide superior adhesion and healing capabilities, addressing unmet medical needs both inside and outside the body.
The UT Arlington Research Institute (UTARI) specializes in applying cutting-edge technologies to real-world engineering problems. Our collaborative endeavors reflect a commitment to excellence, integrity, and respect for all, bringing economic growth and fulfillment to our families, business partners, university, and community.
The University of North Carolina Wilmington (UNCW) is a top doctoral and research institution located in Wilmington, North Carolina. Established in 1947, UNCW has grown to serve nearly 18,000 students and employs about 2,500 staff. The university is dedicated to providing a powerful academic experience that fosters creative inquiry, critical thinking, and thoughtful expression in a beautiful coastal setting. UNCW is committed to educational excellence, community engagement, and global connections, making it a vibrant part of the southeastern North Carolina community. UNCW also emphasizes the importance of freedom of expression and mutual respect within its diverse community.
The University of Missouri-Kansas City (UMKC) is dedicated to transforming today's learners into tomorrow's leaders through innovative education, research, and community engagement. With over 125 academic programs, UMKC fosters a diverse and inclusive environment that empowers students to achieve their goals and make a positive impact in their communities.
Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world, dedicated to providing high-quality, patient-centered care. With a history of innovation spanning nearly 150 years, Mayo Clinic is committed to transforming healthcare through research, education, and compassionate care, ensuring that the best possible treatment is available to everyone.
Draper is an independent nonprofit engineering innovation company with a legacy spanning over 90 years, dedicated to delivering transformative solutions for national security, prosperity, and global challenges. Renowned for its pioneering work in guidance, navigation, and control (GN&C) systems, Draper partners with government, industry, and academia to engineer advanced technologies in space, defense, biotechnology, and electronic systems. The company leverages multidisciplinary expertise, digital engineering, and a collaborative approach to provide field-ready prototypes, mission-critical systems, and innovative research. Draper’s mission is to ensure the nation's security and prosperity by delivering sustainable, cutting-edge solutions that address the toughest problems of today and tomorrow, while fostering an inclusive and diverse workforce. Draper also invests in the next generation of innovators through robust educational programs, including internships, co-ops, and the Draper Scholars Program, integrating academic research with real-world problem-solving.
Temple University is Philadelphia’s only public university and a global center of academic excellence. It is classified as an R1 institution, indicating very high research activity, and offers over 600 academic programs across 17 diverse schools and colleges. The university is committed to providing accessible education that fosters positive change and prepares students to become leaders in their fields. Additionally, Temple emphasizes a vibrant campus life enriched by arts, culture, and a commitment to diversity and inclusivity. The university also promotes a tobacco-free environment to enhance the health and well-being of its community. Temple's athletics program further enhances student life, with 19 varsity teams competing at the NCAA Division I level, fostering school spirit and community engagement.
The Office of Sponsored Projects Administration (OSPA) at the University of Kentucky is dedicated to transforming tomorrow by streamlining grants and contracts. OSPA provides essential services to faculty and staff, including assistance with proposal preparation, award negotiation, and compliance with sponsor policies.
Southwest Research Institute (SwRI) is a nonprofit research and development organization that provides independent, premier services to government and industry clients. Founded in 1947, SwRI is committed to advancing science and technology to benefit humanity, focusing on innovative solutions that improve human health and safety. With a diverse range of technical divisions, SwRI addresses complex challenges in various fields including mechanical engineering, materials, aerospace, automotive, biomedical, and more.
The University of Texas at Dallas (UT Dallas) is a top public research university located in Richardson, Texas, known for its innovative programs, renowned faculty, and a commitment to academic excellence. With over 31,000 students across seven schools, UT Dallas offers a diverse range of undergraduate and graduate programs designed to prepare students for leadership roles in various fields including science, engineering, business, and the arts. The university emphasizes research, community engagement, and student success, making it a vibrant hub for learning and innovation. Additionally, UT Dallas is recognized for its strong return on investment, high graduation rates, and successful career placement for graduates, with many students continuing their education at prestigious graduate schools.
Macro Biologics, Inc. is dedicated to designing, patenting, and producing macro biologics, which are large molecule biologics with both physical properties and functional activities. These biologics are composed of natural building blocks, such as amino acids or carbohydrates, and are designed to degrade back into their natural components, making them environmentally friendly. The company aims to address significant global challenges, such as antibiotic resistance and pollution, by providing biologics that are safe for both people and the environment. Macro Biologics is committed to the highest standards of science, medicine, and business, with a focus on healthcare applications.
NANOMEDICINE MANUFACTURING LABORATORY Nanomedicine Manufacturing Laboratory (NML) is a research and development laboratory specializing in nanomaterials and biomaterials for imaging, oxygen delivery, and drug delivery, with a core emphasis on scalable manufacturing and Quality-by-Design (QbD). More informaiton about NML: https://www.duq.edu/research/faculty-research/nanomedicine-lab/nanomed-lab-research.php Led by Dr. Jelena M. Janjic, the Nanomedicine Manufacturing Laboratory develops colloidal nanosystems and implantable biomaterials that support molecular imaging modalities, including magnetic resonance imaging (MRI) and near-infrared fluorescence; biosensing, drug delivery; oxygen delivery; and theranostic nanomaterials, used for local and parenteral administration or as implantable biomaterials. A major barrier to the advancement of nanotechnology-based therapeutics is not conceptual innovation but manufacturability, cost, and quality control. The Nanomedicine Manufacturing Laboratory addresses these challenges by incorporating manufacturing process design, scalability, and quality control at the earliest stages of material design. Over the past decade, the laboratory has established robust, reproducible, and cost-effective nanomedicine manufacturing methods by applying QbD frameworks, enabling reliable scale-up and controlled performance. The laboratory’s work is supported by the U.S. Air Force, the Congressionally Directed Medical Research Programs (CDMRP), and ARPA-H through collaborative programs spanning academia, industry, and government. The Nanomedicine Manufacturing Laboratory operates at the intersection of materials science, manufacturing, and translational medicine, with a focus on developing innovative nanomedicines and biomaterials that translate into accessible, cost-effective future treatments for civilian and military medical needs.
The University of Arizona Applied Research Corporation (UA-ARC) is a non-profit organization affiliated with the University of Arizona, dedicated to leveraging the university's strengths in research and education to address national security challenges. UA-ARC aims to deliver innovative solutions and foster collaborations between academia, industry, and government.
The University of Utah (UU) is a leading research institution recognized for its research activity and commitment to innovation and discovery. As an R1 Institution, it is dedicated to advancing knowledge and solving critical problems that challenge our national security interests and impact the global community. We foster interdisciplinary collaboration and provide resources to drive transformative research focused on enhancing medical care superiority for the U.S. Department of Defense (DoD) through advanced medical and engineering research sponsored by our Applied Medical & Engineering Laboratory (AM&E Lab). As a leading public university, UU also provides healthcare services to seven states in the Intermountain West, with the largest catchment of remote and austere frontier territory for any academic center. Leveraging its geographic advantage, technological and commercialization strengths, expertise in medical services, and leading-edge, core engineering competencies, UU is uniquely positioned to address the nation's critical national security interests.
The Institute for Biohealth Innovation (IBI) at George Mason University unites over 300 faculty and thousands of students across 34 departments to advance human health and well-being through innovative research. The IBI focuses on major health challenges, including infectious diseases, cancer, brain and behavior, and cardiovascular health, collaborating with national and international partners to implement solutions that enhance health outcomes.
Stemora Bio develops stem cell-based therapies focused on cartilage regeneration for osteoarthritis treatment, aiming to restore mobility and offer new therapeutic options for osteoarthritis.
Microbiotix, Inc. is a clinical stage biopharmaceutical company dedicated to the discovery and development of proprietary small molecule drugs targeting serious infectious diseases, including multi-drug resistant pathogens. The company is recognized for its innovation and has consistently been a top recipient of NIH awards among Massachusetts biotech/pharma companies.
The University of Minnesota's Research and Innovation Office (RIO) serves as a central resource for conducting, managing, and sponsoring research. It aims to facilitate collaborative research that addresses complex problems and promotes innovations that improve lives. RIO oversees research compliance and administration, fostering a culture of integrity and ethical practices in research. Additionally, RIO is committed to enhancing research capacity through various funding opportunities and strategic initiatives, including the management of specialized facilities for biocontainment research.
The University of Notre Dame, founded in 1842, is a prestigious Catholic research university located in South Bend, Indiana. It is dedicated to providing a holistic education that integrates faith, reason, and service to others. The university aims to be a leading global Catholic research institution, fostering a community of scholars committed to inquiry, justice, and the common good.
New York University (NYU) is a global university that connects talented and ambitious individuals in some of the world's greatest cities. Its mission is to be a top-quality institution, providing a diverse range of academic programs and opportunities for students to engage with the world's challenges. NYU is committed to fostering innovation and entrepreneurship, and it emphasizes diversity, equity, and inclusion in its educational mission. Founded in 1831, NYU has evolved to become a leader in higher education, with a commitment to accessibility and a diverse student body. NYU offers a wide array of academic programs, including accelerated studies and online education, catering to the needs of a global student population.
Vasomune Therapeutics is a private clinical-stage biopharmaceutical company focused on developing novel therapeutics for diseases associated with vascular dysfunction. Their lead drug candidate, Pegevongitide (AV-001), enhances the body's ability to reverse vascular endothelial instability and vascular leak, particularly in conditions such as Acute Respiratory Distress Syndrome (ARDS), hemorrhage, and following toxin exposure.
Northwestern University is a prestigious institution dedicated to fostering a diverse and inclusive environment, promoting academic excellence, and engaging in impactful research. With campuses in Evanston, Chicago, and Doha, Qatar, Northwestern emphasizes global engagement and community involvement, preparing students to tackle complex challenges through interdisciplinary collaboration and innovative thinking.
Digital Ether Computing LLC develops adaptive intelligence systems at the intersection of artificial intelligence, drug discovery, and computational biology. Their mission is to accelerate therapeutic innovation and redefine complex system management through advanced AI architectures, including drug design, industrial automation, defense systems, and neuromorphic computing. The company applies foundational research in adaptive AI to real-world applications where reliability, explainability, and continuous self-improvement are critical.
The University of Iowa is dedicated to providing a comprehensive educational experience that fosters academic excellence, research opportunities, and a vibrant student life. With a commitment to accessibility and inclusivity, the university aims to prepare its students for success in various fields while promoting a supportive community.
Case Western Reserve University is dedicated to solving the biggest issues of today and tomorrow through innovative research and education. With a commitment to experiential learning, the university offers a wide range of programs and opportunities for students to engage in research, internships, and community service, all within a vibrant campus located in Cleveland, Ohio.
The University of Alaska Fairbanks (UAF) is a Land, Sea, and Space Grant university and an international center for research, education, and the arts, emphasizing the circumpolar North and its diverse peoples. UAF integrates teaching, research, and public service as it educates students for active citizenship and prepares them for lifelong learning and careers.
The University of South Florida (USF) is a Preeminent Research University and member of the Association of American Universities (AAU), dedicated to empowering students to maximize their potential for lifelong success. With campuses across the vibrant Tampa Bay region, USF serves nearly 50,000 students and offers a wide range of academic programs, innovative research opportunities, and a commitment to community engagement.
New Jersey Institute of Technology (NJIT) is a leading public research university dedicated to providing students with a world-class education in STEM fields and beyond. With a commitment to academic excellence, NJIT prepares students to be leaders in the most in-demand fields through innovative programs, expert faculty, and extensive research opportunities. NJIT is recognized for its affordability and return on investment, making it a top choice for students seeking a quality education. NJIT is also ranked among the top public universities in the nation, known for its diverse student body and commitment to fostering an inclusive environment.
ClearCure Biosciences is a clinical-stage biopharmaceutical company focused on developing non-toxic, first-in-class and best-in-class therapies for cancer, infectious diseases, sepsis, neurological diseases, and cardiovascular conditions. The company emphasizes drugging challenging targets, leveraging proprietary small molecules, nanotechnology, new oncology cell therapies, new transdermal drug delivery technology, AI and omics-driven approaches, and digital health solutions to address serious unmet medical needs. The company is currently seeking collaborators and partnerships.
The University of Arkansas for Medical Sciences Office of Research and Sponsored Programs (ORSP) is dedicated to supporting UAMS faculty in acquiring, performing, and administering projects funded by external sources. The ORSP ensures compliance with policies, negotiates award terms, liaises between investigators and sponsors, and manages subcontracts.
Founded by Thomas Jefferson in 1819, the University of Virginia is a prestigious public university that emphasizes the advancement of human knowledge, education of leaders, and cultivation of an informed citizenry. It is recognized for its commitment to academic excellence, vibrant student life, and a strong alumni network, making it one of the top public universities in the United States.
The University of Missouri is dedicated to advancing research, innovation, and impact through a comprehensive support system for faculty, students, and staff. It aims to foster collaboration, enhance economic development, and promote entrepreneurship, while ensuring compliance with research regulations and ethical standards. The university also emphasizes the importance of interdisciplinary partnerships and provides resources to support veteran entrepreneurs through programs like the Entrepreneurship Bootcamp for Veterans.
The University of Massachusetts Lowell (UML) is dedicated to providing a comprehensive educational experience that prepares students for success in their careers and lives. With over 200 degree programs and a commitment to research and community engagement, UML fosters a vibrant learning environment for its diverse student body.
Aphios is a green biotechnology company focused on developing enabling nanotechnology platforms and enhanced therapeutics for health maintenance, disease prevention, and treatment of various conditions including cancers, infectious diseases, and central nervous system (CNS) disorders. The company emphasizes environmentally-sustainable practices and aims to improve the quality of life through innovative therapies.
The University of Nebraska Medical Center (UNMC) is dedicated to transforming lives through premier educational programs, innovative research, and extraordinary patient care. Founded in 1869, UNMC is a leader in health sciences education and research, serving as a vital resource for Nebraska and beyond.
MassBiologics, part of UMass Chan Medical School, is the only nonprofit, FDA-licensed manufacturer of vaccines and biologics in the United States. With over 100 years of experience, it is dedicated to improving public health through the research, development, and production of biologic products, including vaccines and monoclonal antibodies.
Lovelace Biomedical is a not-for-profit preclinical contract research organization specializing in advancing new therapies, assessing drug and toxicant risks, and characterizing disease using comprehensive in vivo and in vitro models. Leveraging a GLP-compliant facility and scientific collaborations, the organization provides expertise in toxicology, gene therapy, respiratory, infectious disease, neuroscience, and cell biology, with a commitment to quality, regulatory compliance, and advanced analytical capabilities.
Ceres Nanosciences, Inc. is a privately held company based in Northern Virginia, specializing in the development and commercialization of Nanotrap® hydrogel particle technology. Their mission is to deliver innovative products powered by Nanotrap Technology to address life science needs and provide better patient outcomes. Ceres' products enable the capture, concentration, and preservation of low-abundance analytes from diverse biological and environmental samples, supporting applications in diagnostics, research, and public health surveillance. The company is ISO 9001:2015 certified and collaborates with leading research institutions, public health agencies, and industry partners to advance global health security and biosecurity. Ceres has established a national network of Wastewater-based Epidemiology Centers of Excellence and has received significant funding from the NIH RADx initiative and other organizations to expand its impact in underserved communities. Their technology is widely adopted for wastewater-based epidemiology, proteomics, and nucleic acid analysis, with a strong focus on supporting public health monitoring, early detection of infectious diseases, and environmental bio-surveillance.
The Medical University of South Carolina (MUSC) is South Carolina’s premier biomedical research institution, dedicated to advancing health through innovative research, education, and clinical care. With over $300 million in research funding and a commitment to addressing pressing health challenges, MUSC fosters collaboration among faculty, staff, and community partners to translate scientific discoveries into impactful health solutions. The South Carolina Clinical & Translational Research Institute (SCTR) at MUSC supports innovative research across the translational spectrum, from basic science to population health, including patient-centered and community-engaged research.
The University of Florida is a leading public university that fosters innovation, education, and research. With a commitment to excellence, the university provides a diverse and inclusive environment for students, faculty, and staff, driving impactful discoveries and community engagement.
The UCI Office of Research is dedicated to supporting and enhancing the creative and scholarly activities of UCI faculty and researchers. It provides central administrative support for research programs, ensuring compliance with regulations and fostering an environment conducive to research and innovation.
Hemerus Medical, LLC specializes in designing and developing innovative blood collection, processing, preservation, and storage technologies. Our mission is to improve patient transfusion outcomes and ensure the availability of high-quality, life-saving blood products. Hemerus aims to extend the shelf life of blood products and enhance transfusion safety through advanced technologies like leukocyte reduction filters and novel anticoagulant and additive solutions.
Virginia Tech is a leading research institution dedicated to improving the quality of life and the human condition through education, research, and community engagement. With a commitment to its motto, 'Ut Prosim' (That I May Serve), Virginia Tech fosters a collaborative environment that integrates technology into all disciplines, preparing scholars to be leaders and problem-solvers.
Adaptyx Biosciences is developing a wearable platform for continuous monitoring of multiple biomarkers in dermal interstitial fluid from a single device at the point of need. Built on programmable molecular switch technology that can be reprogrammed across hormones, drugs, electrolytes, peptides, and proteins, it is a single platform adaptable to needs spanning Military Operational Medicine, Combat Casualty Care, Military Infectious Diseases, Clinical and Rehabilitative Medicine, and Chemical, Biological, and Radiological Defense. The platform draws on more than 17 years of pioneering research from our team at Stanford. We have prototype sensors ready for R&D today, and have already demonstrated continuous measurement of multiple biomarkers in humans, including multi-day free cortisol monitoring that captures the diurnal rhythm conventional single-timepoint tests cannot see.
LSU Health Sciences Center New Orleans is dedicated to educating future health professionals and scientists, advancing research, and providing exceptional healthcare. With six professional schools and numerous affiliated hospitals, LSUHSC-NO aims to improve health outcomes and address health equity challenges in Louisiana.
The University of Texas Permian Basin (UTPB) offers a modern, affordable education in the heart of West Texas, focusing on student success and community impact. With a commitment to providing a diverse range of undergraduate and graduate programs, UTPB aims to empower students to achieve their academic and career goals while contributing positively to the region. UTPB also emphasizes professional development through innovative programs like the Coursera Career Academy and the Impact Behavioral Health Scholarship, which covers tuition and fees for graduate students in specific programs.
Relevium Medical is a pharmaceutical company based in Ireland and the US, founded in 2019 as a spin-out from the University of Galway’s BioInnovate Programme, the only European affiliate of Stanford BioDesign. With support from Y Combinator, Enterprise Ireland and the European Innovation Council, the company is developing novel hydrogel-based therapeutics for chronic disorders, leveraging natural biopolymers and active agents for targeted, long-lasting treatment. Relevium has a world-class clinical advisory board and a growing pipeline including products for osteoarthritis, painful bladder, neurogenic bladder, & trauma wound infections. To date the company has secured a total of $8 million non-dilutive funding and private seed investment.
Biophoundry specializes in advancing scalable engineered phage-based solutions for therapeutics, diagnostics, and bio-molecular engineering. It is shifting the paradigm from phage discovery to phage design. Its team leverages expertise in synthetic biology, machine learning, and data science to accelerate the development of precision antibiotics and address critical healthcare challenges such as antimicrobial resistance.
Northeastern University is a global research university founded in 1898, renowned for its experiential learning model, high-impact research, and deep partnerships. The university emphasizes innovative teaching and research that engage students, faculty, and alumni in solving real-world problems, fostering a dynamic and inclusive community across its 13 campuses worldwide.
Texas Biomedical Research Institute is dedicated to pioneering and sharing scientific breakthroughs to protect global communities from infectious diseases. With over 80 years of experience, it combines high-level biocontainment labs, a National Primate Research Center, and a commitment to advancing diagnostics, vaccines, and therapies. The institute also emphasizes education and outreach, providing resources and programs to engage students and teachers in scientific research.
The University of Montana (UM) is a flagship public research university located in Missoula, Montana. Established in 1893, UM offers a wide range of undergraduate and graduate programs, emphasizing research, creativity, and community engagement. With a commitment to academic excellence and public service, UM aims to transform lives through education and research, fostering a diverse and inclusive environment for its students.
The University at Buffalo is a leading public research university and flagship of the SUNY System, recognized for its innovative research and commitment to societal impact. It aims to transform scientific and technological breakthroughs into global impact, addressing complex challenges through interdisciplinary collaboration.
Cocrystal Pharma is a clinical-stage biotechnology company specializing in the discovery and development of novel antiviral therapeutics for serious and chronic viral diseases such as influenza, COVID-19, hepatitis C, norovirus, and other respiratory viruses. The company leverages structure-based drug discovery technology and expertise in structural biology to design direct viral replication inhibitors with broad-spectrum activity. Its pipeline includes candidates in preclinical and clinical development, addressing unmet needs in antiviral medicine.
Egret Therapeutics is a biotechnology company developing a novel therapy that targets the immune-mediated component of secondary neuronal damage to improve recovery after TBI. Our therapy has potential applications across combat injury (TBI, SCI, MSK, and polytrauma) and civilian markets (heart attack, stroke), where immune-mediated secondary damage leads to devastating outcomes.
UC San Francisco is a leading university dedicated to advancing health worldwide through preeminent biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. With a commitment to public service, UCSF aims to innovate health care approaches for vulnerable populations and train the next generation of health professionals.
The University of Pennsylvania (Penn), founded in 1740 by Benjamin Franklin, is a world-renowned Ivy League institution located in Philadelphia. Penn is dedicated to advancing knowledge, fostering innovation, and making a positive impact locally and globally. With a strong commitment to interdisciplinary research, academic excellence, and community engagement, Penn offers a diverse and inclusive environment for students, faculty, and staff. The university is recognized for its leadership in research, robust financial aid programs, and a tradition of civic involvement. Penn's strategic initiatives, such as Penn Forward, focus on reshaping education, research, and service to meet the challenges of a rapidly changing world. The university is also a leader in sustainability, aiming for carbon neutrality by 2042 and net-zero endowment emissions by 2050, and is home to a vibrant ecosystem of innovation, global engagement, and community partnership.
UTHealth Houston is Texas’ resource for health care education, innovation, scientific discovery, and excellence in patient care. Since 1972, UTHealth Houston has been dedicated to educating the next generation of health care professionals, advancing biomedical research and public health, and providing exceptional care to communities. With half a century of experience, it is one of the nation’s most comprehensive academic health centers, committed to advancing the quality of human life through education, research, and clinical practice.
SUNY Upstate Medical University is a leading academic medical center in Central New York, dedicated to providing exceptional patient care, advancing medical research, and educating future healthcare professionals. As the region's only Level I trauma center and a Magnet recognized institution, Upstate is committed to delivering cutting-edge, life-saving treatments and fostering a compassionate, patient-centered environment. The university also plays a significant role in the community through outreach programs and is recognized as one of America's best large employers by Forbes.
SK pharmteco is a global contract development and manufacturing organization (CDMO) serving the pharmaceutical and biotechnology sectors with integrated solutions spanning small molecule synthesis, peptides, advanced modalities, and viral vector manufacturing. The company operates CGMP facilities across the US, Europe, and Asia, supporting clients from preclinical to commercial supply. Its offerings include process and analytical development, custom manufacturing, regulatory support, cell and viral banking, and the application of sustainable practices throughout the product lifecycle. Environmental responsibility, compliance, and innovation in manufacturing and analytics are core to their operations.
Washington State University (WSU) is a public research university dedicated to improving lives by serving the public good. With a commitment to unlocking possibilities, WSU empowers students, faculty, and others to create a world where all people can thrive. The university offers a diverse range of academic programs across its six campuses and is recognized for its high research activity and community engagement.
Northstar owns IP around the use of antibody fragments and nucleic acids to rapidly diagnose and treat bacterial and viral infections. With numerous applications to sepsis and bioterrorism countermeasure, Northstar seeks partnerships with other forward thinking companies and government entities to protect our military and enhance homeland security.
Tolka AI Therapeutics is a biotechnology company focused on developing personalized phage therapy solutions for hard-to-treat, antibiotic-resistant infections. By integrating agentic artificial intelligence, robotics, and advanced manufacturing, the company enables scalable, tailored therapies targeting pathogens such as Mycobacterium abscessus. Tolka leverages a proprietary phage library, automated platforms, and clinical research programs to accelerate access to safe and effective alternatives where conventional treatments are inadequate.
UCLA is a leading public research university located in Los Angeles, California. It is renowned for its commitment to the creation, dissemination, preservation, and application of knowledge for the advancement of global society. With a rich history of academic and athletic excellence, UCLA offers a comprehensive environment that supports both academic and personal growth. The university is dedicated to fostering innovation and making a significant impact on the world through groundbreaking research and transformative practices.
Genomind is a leader in precision medicine for mental health, dedicated to helping healthcare providers and patients make better prescribing decisions by leveraging genetic, lifestyle, and environmental data. Their mission is to personalize mental health treatment and improve outcomes for individuals, providers, and healthcare systems. Genomind supports a wide range of stakeholders, including individuals, providers, long-term care facilities, ACOs, employers, health plans, and international partners. Through innovative pharmacogenetic testing, precision medicine software, consultative services, and educational resources, Genomind aims to advance mental health care and empower both patients and professionals.
The Office of Sponsored Programs (OSP) at Georgia Tech provides comprehensive support for research administration, including proposal preparation, contract negotiation, and compliance with federal and state regulations. OSP aims to facilitate research by offering educational resources, guidance, and administrative support to faculty and research administrators throughout the award lifecycle. Additionally, OSP is committed to improving and modernizing contract management processes, ensuring compliance with various agreements, and fostering collaborative research efforts.
Rx Bandz is dedicated to developing innovative, next-generation auto-injectors and life-saving formulations that provide simple solutions for patients, first responders, and the military. Their mission is to enhance the delivery of injectable medications, ensuring accessibility and ease of use for anyone, anytime, anywhere.
Arizona State University (ASU) is a comprehensive public research university known for its commitment to inclusivity, excellence, and societal impact. ASU is dedicated to advancing research-based solutions for global challenges, fostering strong leadership, and providing quality education accessible to all learners. The university is recognized for its innovative approach to education and its efforts in sustainability, research, and community service. ASU exemplifies a new prototype for the American public research university, focusing on excellence, broad access to quality education, and meaningful societal impact.
The Vanderbilt School of Engineering is a globally recognized academic and research institution dedicated to producing leaders and innovators in engineering. With a commitment to solving grand challenges, the school offers a diverse range of undergraduate and graduate programs across multiple engineering disciplines, fostering a culture of collaboration and excellence.
The Medical College of Wisconsin (MCW) is dedicated to transforming healthcare through innovative education, research, and patient care. With a focus on academic medicine, MCW aims to improve the health of communities by fostering a collaborative learning environment that integrates medical education with groundbreaking research and comprehensive patient care.
The University of California San Diego (UC San Diego) is a leading public research university located in La Jolla, California with over $1.79B in research expenditures. Known for its innovative and interdisciplinary approach, UC San Diego offers a wide range of undergraduate, graduate, and professional programs across various fields. UC San Diego is recognized for its contributions to research and innovation, particularly in areas such as national defense, energy, data science, climate science, health innovation, and artificial intelligence. We also have the nation's first undergraduate program promoting projects and start up devoted to National Security Innovation (4iNS).
UT Health San Antonio is dedicated to educating the next generation of health care professionals, conducting innovative research, and providing high-quality patient care. With a commitment to community service, the institution aims to improve health outcomes in South Texas and beyond through its six schools and numerous degree programs.
Indiana University is dedicated to building a better future through education, research, and community engagement. With a commitment to academic excellence, IU offers a diverse range of programs across its nine campuses, fostering an inclusive environment for over 90,000 students from around the world. IU is also at the forefront of groundbreaking research, particularly in areas such as brain health and Alzheimer's disease.
ARIScience is at the forefront of drug discovery, leveraging a unique combination of AI, quantum chemistry, computer vision, and biochemistry to develop novel small molecule drugs. Their mission is to reduce the burden of human disease by discovering therapeutics that interrupt disease pathways. With a focus on neurodegenerative, inflammatory, and infectious diseases, ARIScience employs cutting-edge in silico methods to efficiently identify and optimize drug candidates. Their commitment to innovation and collaboration with leading institutions positions them to make a significant impact on human health. ARIScience is creating value in two ways: Value 1: ARIScience is developing small molecule assets targeting respiratory depression, cutaneous burn and radiation injuries, antivirals for EBOV and DENV, bacteriostatic antibiotic targeting Staph aureus. Value 2: It's novel AI driven quasi quantum chemistry (AI+QQ) small molecule discovery platform for precision protein inhibition and potentiation.
UT Southwestern Medical Center is a premier academic medical institution dedicated to advancing medical science and improving health care through excellence in education, research, and patient care. The center is renowned for its collaborative environment that fosters innovation and discovery, housing distinguished faculty including Nobel Laureates. UT Southwestern is recognized for its groundbreaking research, comprehensive educational programs, and commitment to patient care, serving millions annually across its facilities.
Yale University, founded in 1701, is dedicated to expanding and sharing knowledge, inspiring innovation, and preserving cultural and scientific information for future generations. It engages with local and global communities to promote cultural understanding and improve the human condition.
Stanford University, founded nearly 150 years ago, is dedicated to educating students for lives of leadership and contribution with integrity. The university emphasizes advancing fundamental knowledge, cultivating creativity, and pioneering research for effective clinical therapies, while also focusing on societal impact and solutions.
The University of Tennessee, Knoxville is dedicated to advancing knowledge and understanding through research, scholarship, and creative work. The Office of Research, Innovation, and Economic Development supports faculty, staff, and students in developing competitive proposals and fostering a strong culture of research integrity, aiming to create a more just, prosperous, and sustainable world.
UC Davis, founded in 1908, is a top-tier public university located in California, known for its commitment to education, research, and public service. It offers a diverse range of academic programs and is recognized for its contributions to agriculture, veterinary medicine, and sustainability. The university fosters a collaborative environment that encourages innovation and inclusivity, aiming to enhance the lives of its students and the broader community. Additionally, UC Davis is strategically located in the heart of Northern California, providing easy access to major attractions, including beaches, wine country, and national parks.
OrthoTreat is dedicated to advancing bone regeneration through innovative solutions that enhance the body's physiological healing mechanisms. Their unique approach, OsteoRegulation, focuses on optimizing biological processes rather than merely providing materials for bone formation, aiming for faster, better, and stronger healing outcomes.
SPOC Biosciences is a life sciences technology company focused on advancing proteomics through high-plex biosensor chip platforms. The company enables high-throughput, cost-effective protein production and deep characterization of protein interactions using techniques such as cell-free expression and multiplexed SPR biosensing. Their platform accelerates drug discovery, AI-driven drug design, biomarker identification, diagnostics, antibody screening, and vaccine development by generating scalable, high-resolution kinetic datasets suitable for advanced analytics and AI model training.
Founded in 2015, Omnix Medical is a clinical-stage biopharmaceutical company dedicated to developing novel antibiotic agents to combat infections caused by drug-resistant bacteria. Their innovative technology focuses on natural antimicrobial peptides, engineered for therapeutic use, targeting severe hospital-acquired infections and addressing the urgent threat posed by multidrug-resistant pathogens. The company is building a pipeline of first-in-class anti-infectives designed to treat severe, potentially lethal infections associated with multi-drug resistances.
Peptilogics U.S.-based clinical-stage biotechnology company developing first-in-class engineered peptide therapeutics for the treatment and prevention of medical device–related infections (MDRI) and other serious wound infections, where bacterial biofilms defeat conventional antibiotics and the immune system, and no anti-biofilm therapy is approved. Our lead asset, zaloganan (PLG0206), is a rationally engineered peptide that rapidly eradicates biofilm-associated and planktonic bacteria across a broad spectrum of drug-resistant pathogens. Following positive Phase 1b results, zaloganan has advanced to a pivotal Phase 2/3 trial (RETAIN) for periprosthetic joint infection and holds FDA Orphan Drug, Fast Track, and QIDP designations. A controlled-release zaloganan program in non-clinical development extends the franchise into broad-spectrum infection prevention, with trauma/fracture related infection prevention as the initial indication. Peptilogics is building a treatment-and-prevention franchise across the MDRI landscape, and beyond.
Omniox is an IND-stage biotherapeutics company focused on developing innovative H-NOX platform technology into first-in-class and best-in-class OMX oxygen delivery vehicles. These biologics are designed to safely deliver oxygen to hypoxic tissues, addressing significant unmet medical needs and improving patient outcomes.
The Center for Military Medicine Research (CMMR) at the University of Pittsburgh is dedicated to advancing medical research for wounded service members and their families. The center focuses on trauma, emergency, and critical care, leveraging the university's strengths in medical and engineering fields, and collaborating with Carnegie Mellon University's robotics and AI expertise. CMMR aims to enhance trauma care for warfighters and civilians, contributing to the defense innovation economy.
The Texas A&M Engineering Experiment Station (TEES) is a state agency and part of the Texas A&M University System, dedicated to improving lives through engineering research, workforce development, and technology transition. TEES collaborates with industry, academia, and government to provide innovative solutions to global technical challenges.

NIRSense
Rugged Physiological Monitoring for the Modern Warfighter: NIRSense
Under MTEC-21-10-NavyMultiTopic, NIRSense is advancing its tactical jet physiological monitoring technology for broader Navy applications. The project focuses on ruggedized, wireless physiological sensors that can provide reliable, real-time insight into warfighter health and performance in demanding operational environments.
Safi Biotherapeutics
Next-Generation Manufactured Red Blood Cells for Extended Battlefield Blood Supply: Safi Biotherapeutics
Safi Biotherapeutics is developing manufactured red blood cells (mRBCs) with extended shelf life to improve battlefield transfusion readiness and emergency trauma care.
Non-Invasive Glymphatic (GF) Monitoring and Recovery Optimization for Warfighter Cognitive Readiness
Applied Cognition is developing non-invasive glymphatic monitoring and recovery technologies to enhance warfighter cognitive readiness, resilience, and sleep recovery.
Moberg Analytics
Moberg Analytics – Advanced Brain Monitoring & Critical Care Informatic
Moberg’s platform unifies brain monitoring data for faster, precise treatment of severe brain injuries in military and civilian care.