Member

Kilobaser (MABEAL GmbH)


Kilobaser develops benchtop DNA and RNA synthesizer platforms that enable decentralized, on-demand synthesis of custom oligonucleotides for scientific research, diagnostics, and data storage. Their technology leverages microfluidic chips and cartridge-based reagent delivery, automating solid-phase synthesis processes in a user-friendly system. Kilobaser's mission is to democratize access to nucleic acid synthesis, supporting rapid prototyping, molecular biology workflows, and emerging fields like DNA data storage.

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Kilobaser (MABEAL GmbH)


Products

Benchtop device for custom DNA and RNA oligonucleotide synthesis, using microfluidic chips and cartridge-based reagent delivery. Enables solid-phase synthesis of standard and modified oligos, including dual-labeled probes. Features touchscreen, mobile, and PC control; supports both online and secure offline use.

Disposable microfluidic chips containing solid-phase columns with functional end modifications to support various synthesis protocols and labeling strategies.

Pre-filled reagent cartridges for various oligonucleotide syntheses, including options for backbone modifications, fluorescent labeling, biotinylation, phosphorylation, and click chemistry.

Hydrophobic interaction chromatography kit for single-spin purification, enabling removal of salts and free dyes from synthesized oligonucleotides.

Compact benchtop nitrogen generator supplying inert gas for synthesizer operation, replacing pressurized gas cylinders.

Single-use service for trial synthesis of custom oligos to assess quality before device purchase.

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Services

Support for installation and onboarding, including virtual or on-site guidance through device setup and operation.

Technical and scientific assistance for interpreting synthesis results, troubleshooting, and experimental setup.

Client-specific design and development of oligonucleotide modifications and synthesis protocols.

Expertise Areas

  • DNA and RNA synthesis
  • Oligonucleotide modification
  • Microfluidic chip-based chemical synthesis
  • Molecular diagnostics
  • Show More (6)

Key Technologies

  • Microfluidic chip technology
  • Solid-phase oligonucleotide synthesis
  • Cartridge-based reagent delivery
  • Phosphoramidite chemistry
  • Show More (5)

Key People

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News & Updates

Launch of a click chemistry-enabled cartridge facilitating terminal alkyne modification of oligonucleotides.

Introduction of a new oligonucleotide purification kit using hydrophobic interaction chromatography for single-spin desalting and dye removal.

Launch of a compact nitrogen generator for laboratory DNA/RNA synthesis workflows.

Overview of Kilobaser's participation in the DNAMIC project, developing an autonomous DNA data storage microfactory.

Demonstration of in-house synthesis and purification of DNA templates for sgRNA production, enabling effective CRISPR/Cas9 genome editing workflows.

International conference focused on DNA-based data storage and computation, co-organized through EIC’s DigNA/DNAMIC initiatives, with Kilobaser contributing decentralized DNA synthesis technology for data storage applications.

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