Cube Dx GMBH
Developer and manufacturer of multiplex molecular in‑vitro diagnostic tests and automated benchtop laboratory instruments. Focus areas include high‑plex molecular panels for bacterial, fungal and resistance‑gene detection from small sample volumes (including whole blood), microarray‑based identification workflows with integrated analysis software, extraction‑free protocols for selected sample types, and amplicon‑based mutation screening for viral surveillance. Provides regulatory documentation, safety data sheets, protocols and customer support.
Industries
Nr. of Employees
small (1-50)
Cube Dx GMBH
Patents
Products
Multiplex pathogen detection assay for small-volume whole blood
Assay workflow combining host‑DNA depletion, multiplex PCR and array‑based identification to detect bacterial and fungal targets plus resistance genes from 0.5 mL whole blood with automated reporting.
Automated benchtop processing and analysis instrument
Automated instrument that processes array cartridges, executes assay protocols, performs automated analysis and generates electronic reports with result archiving and visualization.
Amplicon‑based viral mutation screening workflow
Two‑step workflow: RT‑PCR amplicon generation followed by rapid high‑plex SNP discrimination to identify dozens of mutations and infer likely variants; validated for clinical and aggregate (e.g., wastewater) samples.
Multiplex pathogen detection assay for small-volume whole blood
Assay workflow combining host‑DNA depletion, multiplex PCR and array‑based identification to detect bacterial and fungal targets plus resistance genes from 0.5 mL whole blood with automated reporting.
Automated benchtop processing and analysis instrument
Automated instrument that processes array cartridges, executes assay protocols, performs automated analysis and generates electronic reports with result archiving and visualization.
Amplicon‑based viral mutation screening workflow
Two‑step workflow: RT‑PCR amplicon generation followed by rapid high‑plex SNP discrimination to identify dozens of mutations and infer likely variants; validated for clinical and aggregate (e.g., wastewater) samples.
Services
Customer technical support and downloadable manuals, IFUs, protocols and SDS documents.
Customer technical support and downloadable manuals, IFUs, protocols and SDS documents.
Expertise Areas
- Multiplex molecular diagnostics
- Molecular microbiology for infectious disease
- Microarray‑based assay development and solid‑phase detection methods
- Automated laboratory instrumentation and integrated data analysis
Key Technologies
- Microarray‑based compact sequencing (array hybridization with solid‑phase primer extension)
- Cylindrical rotating microarray format
- Multiplex PCR / RT‑PCR
- Amplicon‑based high‑plex SNP discrimination
News & Updates
Discussion of a combined workflow that provides a broad test panel with rapid results for pathogen detection (compact sequencing).
Article describing extraction‑free BAL testing using a modulation buffer to shorten time to result and the application of a reduced panel for pneumonia diagnostics.
Awarded first place in the Houska Prize 2023 (category: Research & Development in SMEs) for work on rapid sepsis diagnostics (compact sequencing); prize funding intended to support further research.
Discussion of a combined workflow that provides a broad test panel with rapid results for pathogen detection (compact sequencing).
Article describing extraction‑free BAL testing using a modulation buffer to shorten time to result and the application of a reduced panel for pneumonia diagnostics.
Awarded first place in the Houska Prize 2023 (category: Research & Development in SMEs) for work on rapid sepsis diagnostics (compact sequencing); prize funding intended to support further research.