DNA Script


DNA Script is a pioneering biotechnology company focused on revolutionizing DNA synthesis through enzymatic technology. Their mission is to accelerate scientific discovery and innovation by providing fast, accurate, environmentally sustainable, and on-demand DNA synthesis solutions, including the SYNTAX platform and custom synthesis services. They collaborate globally to address healthcare challenges, support research, and develop advanced genetic tools, aiming to make synthetic DNA accessible and customizable for researchers worldwide.

Industries

biotechnology
health-care
life-science
medical

Nr. of Employees

large (251-1000)

DNA Script

67 avenue de Fontainebleau, 94270 Le Kremlin-Bicêtre, France


Patents

Variants of terminal deoxynucleotidyl transferase and uses thereof

US-12286652-B2

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Variants of family a DNA polymerase and uses thereof

US-12173333-B2

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Reagents and methods used in deprotection of 3'-O-amino polynucleotides

US-12163172-B2

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Variants of terminal deoxynucleotidyl transferase and uses thereof

US-12071638-B2

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Methods for extending polynucleotides

US-11993773-B2

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Efficient product cleavage in template-free enzymatic synthesis of polynucleotides

US-11905541-B2

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Products

Benchtop enzymatic DNA synthesis instrument

An on‑site laboratory instrument that performs enzymatic oligonucleotide synthesis with simplified user workflows, designed to produce custom DNA oligos rapidly without specialized training.

On-demand ssDNA oligonucleotides (service)

Custom single-stranded DNA oligonucleotides delivered as a synthesis service, supporting lengths up to ~500 nt and sequences that are challenging with chemical synthesis (long poly(A) tails, repeats, high GC).


Services

Custom single-stranded DNA synthesis offered as an on-demand service for research customers, supporting long and complex sequences (poly(A) tails, ITRs, high-GC regions) with sequence verification and delivery.

Laboratory instrument for in-house enzymatic oligonucleotide synthesis that enables rapid production of custom DNA oligos with user-friendly workflows and local sequence control.

Membership program providing early access to new instrument capabilities, preferential pricing, prioritized support, and collaboration opportunities to test and shape new functionality.

Project-based collaborations and technical support to integrate enzymatic oligo synthesis into vaccine template generation, diagnostic assay optimization (qPCR/NGS), and other translational projects; includes joint experiments and application-specific protocol development.

Operational services covering delivery coordination, instrument installation, maintenance, reagent and spare part coordination, and customer support to ensure instrument uptime and order fulfilment.

Expertise Areas

  • Enzymatic DNA synthesis
  • Oligonucleotide production for molecular biology and sequencing
  • Gene assembly (PCA and Gibson-type workflows)
  • Benchtop DNA synthesis instrumentation
  • Show More (5)

Key Technologies

  • Enzymatic DNA synthesis (TdT-based)
  • Reversibly blocked modified nucleotides
  • Solid-support, water-based synthesis
  • Polymerase Cycling Assembly (PCA)
  • Show More (6)

News & Updates

A series of events at US locations from September 28 to October 5, focusing on leveraging enzymatic DNA synthesis for gene assembly.

A recap of a recent webinar discussing enzymatic DNA synthesis for advanced gene construction.

Collaborations to develop on-demand DNA synthesis for vaccines and therapeutics, including the DARPA NOW initiative.


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