XstalBio
XstalBio collaborates with international clients to advance biopharmaceuticals and vaccines by providing innovative technologies, expert consultancy, and scalable solutions to complex bioformulation challenges, accelerating biologics development and delivery.
Industries
Nr. of Employees
small (1-50)
XstalBio
XstalBio Limited, CIDS, Thomson Building, University Avenue, Glasgow G12 8QQ, U.K.
Products
Rapid protein reconstitution method
Method enabling rapid, foam-free reconstitution of high-concentration or viscous protein formulations into syringe-compatible solutions within minutes using standard containers and diluents.
Protein-coated microcrystal pulmonary delivery platform
Respirable dry powder platform based on protein-coated microcrystals providing controlled API payload, good powder handling and particle size control for pulmonary systemic or topical delivery.
Calcium phosphate-coated microcrystal sustained-release platform
Calcium phosphate-coated microcrystals for sustained local delivery of growth factors, hormones or antibodies, configurable for point-of-use preparation or supplied as stable dry powders; compatible with mixing into carriers used in orthobiologics.
Rapid protein reconstitution method
Method enabling rapid, foam-free reconstitution of high-concentration or viscous protein formulations into syringe-compatible solutions within minutes using standard containers and diluents.
Protein-coated microcrystal pulmonary delivery platform
Respirable dry powder platform based on protein-coated microcrystals providing controlled API payload, good powder handling and particle size control for pulmonary systemic or topical delivery.
Calcium phosphate-coated microcrystal sustained-release platform
Calcium phosphate-coated microcrystals for sustained local delivery of growth factors, hormones or antibodies, configurable for point-of-use preparation or supplied as stable dry powders; compatible with mixing into carriers used in orthobiologics.
Services
Contract analytical service providing solid-state CD analysis (rotating cell approach) for secondary and tertiary structure assessment of proteins in particles, lyophilised powders or scattering suspensions, with written interpretation and reporting.
Comprehensive analytical suite for particulate vaccines and colloidal biologics including physico-chemical testing, antigen–particle interaction analysis, particle characterisation, and ICH-aligned stability studies.
Development and manufacture support for respirable dry powder biologics, including particle engineering, performance testing (emitted dose, fine particle fraction) and scale-up to clinical batch production via third-party manufacturing.
Development, optimisation and licensing of particle-based delivery technologies for high-dose, sustained-release and adjuvanted vaccine applications; includes options for point-of-use preparation or supply as ready-made dry powders.
Contract analytical service providing solid-state CD analysis (rotating cell approach) for secondary and tertiary structure assessment of proteins in particles, lyophilised powders or scattering suspensions, with written interpretation and reporting.
Comprehensive analytical suite for particulate vaccines and colloidal biologics including physico-chemical testing, antigen–particle interaction analysis, particle characterisation, and ICH-aligned stability studies.
Development and manufacture support for respirable dry powder biologics, including particle engineering, performance testing (emitted dose, fine particle fraction) and scale-up to clinical batch production via third-party manufacturing.
Development, optimisation and licensing of particle-based delivery technologies for high-dose, sustained-release and adjuvanted vaccine applications; includes options for point-of-use preparation or supply as ready-made dry powders.
Expertise Areas
- Biologic formulation and drug delivery
- Pulmonary drug delivery development
- Vaccine formulation and adjuvant optimisation
- Particle engineering for multi-active delivery
Key Technologies
- Solid-state circular dichroism (near/far-UV)
- Solid-state fluorescence
- Differential scanning calorimetry
- Mass spectrometry (tryptic fingerprinting)