Legacy BioDesign
Legacy BioDesign LLC specializes in biopharmaceutical formulation and assay development, serving clients worldwide for over twenty years. The company is committed to providing high-quality support for formulation projects, with a focus on peptides, proteins, vaccines, and genetic therapies. They emphasize integrity, responsiveness, and creativity, aiming to leave a legacy of excellence and support for their clients.
Industries
Nr. of Employees
small (1-50)
Legacy BioDesign
Johnstown, Colorado, United States, North America
Patents
Products
Books and book chapters on protein formulation
Authored and edited books and book chapters covering theory and practice of stable protein formulation, degradation pathways, and stabilization strategies.
Contract Services for Formulations, Analysis, Stabilization & Delivery of Biotechnology-Based Products
Contract research organization services delivering high-quality support for formulation and assay development of biopharmaceuticals, peptides, and proteins.
Biopharmaceutical Formulation and Assay Development Services
Primary focus lies in the domain of biopharmaceutical formulation and assay development, specializing in the formulation and stabilization of peptides and proteins for parenteral and alternative routes of administration.
Developability Studies
In-depth developability studies using biophysical methods like self-interaction chromatography (SIC) to determine the impact of solution conditions on self-association phenomena, colloidal stability, solubility, aggregation propensity, and viscosity behavior of protein and peptide drug candidates.
Formulation of Other Therapeutics
Specialized formulation support beyond proteins and peptides, including oligonucleotides, antibody-drug conjugates (ADCs), vaccines, and emerging therapeutic modalities.
Biophysical Characterization
In-depth biophysical analysis to reveal how therapeutics behave under various conditions, guiding formulation strategies and demonstrating comparability.
Books and book chapters on protein formulation
Authored and edited books and book chapters covering theory and practice of stable protein formulation, degradation pathways, and stabilization strategies.
Contract Services for Formulations, Analysis, Stabilization & Delivery of Biotechnology-Based Products
Contract research organization services delivering high-quality support for formulation and assay development of biopharmaceuticals, peptides, and proteins.
Biopharmaceutical Formulation and Assay Development Services
Primary focus lies in the domain of biopharmaceutical formulation and assay development, specializing in the formulation and stabilization of peptides and proteins for parenteral and alternative routes of administration.
Developability Studies
In-depth developability studies using biophysical methods like self-interaction chromatography (SIC) to determine the impact of solution conditions on self-association phenomena, colloidal stability, solubility, aggregation propensity, and viscosity behavior of protein and peptide drug candidates.
Formulation of Other Therapeutics
Specialized formulation support beyond proteins and peptides, including oligonucleotides, antibody-drug conjugates (ADCs), vaccines, and emerging therapeutic modalities.
Biophysical Characterization
In-depth biophysical analysis to reveal how therapeutics behave under various conditions, guiding formulation strategies and demonstrating comparability.
Services
Contract research services for formulation, stabilization, assay development, and analytical characterization of biopharmaceutical products.
Development and execution of chromatography, electrophoresis, spectroscopy, calorimetry, AF4-MALLS, and dynamic imaging methods for stability and aggregate assessment.
Application of multivariate statistical tools and design of experiment strategies to interpret screening studies, optimize formulations, and analyze manufacturing data.
Educational short courses focused on peptide and protein formulation and stabilization.
A subscription offering intended to keep clients informed on developments relevant to formulation and assay development.
Contract research services for formulation, stabilization, assay development, and analytical characterization of biopharmaceutical products.
Development and execution of chromatography, electrophoresis, spectroscopy, calorimetry, AF4-MALLS, and dynamic imaging methods for stability and aggregate assessment.
Application of multivariate statistical tools and design of experiment strategies to interpret screening studies, optimize formulations, and analyze manufacturing data.
Educational short courses focused on peptide and protein formulation and stabilization.
A subscription offering intended to keep clients informed on developments relevant to formulation and assay development.
Expertise Areas
- Protein and peptide formulation
- Developability assessment and candidate selection
- Analytical method development and orthogonal characterization
- Aggregate and subvisible particle characterization
Key Technologies
- High-performance liquid chromatography (HPLC/UHPLC)
- Size-exclusion chromatography (SEC)
- Reversed-phase, ion-exchange, hydrophobic interaction chromatography
- Asymmetrical flow field-flow fractionation (AF4)
News & Updates
Celebrating 20 years of service in May 2024, with clients in nearly 20 countries and several drugs in late-stage trials or marketed.
A highly cited review article published in 2010, recognized as a Highly Cited Article by Web of Science.
Scientists at Legacy have been named as inventors on over 50 US patents related to formulation and biopharmaceuticals.
Celebrating 20 years of service in May 2024, with clients in nearly 20 countries and several drugs in late-stage trials or marketed.
A highly cited review article published in 2010, recognized as a Highly Cited Article by Web of Science.
Scientists at Legacy have been named as inventors on over 50 US patents related to formulation and biopharmaceuticals.