Xeltis


Xeltis is an innovative medtech company dedicated to developing regenerative cardiovascular solutions that leverage endogenous tissue restoration (ETR) technology. With a focus on creating self-healing, durable vessels and valves, Xeltis aims to transform treatment options for vascular and heart diseases. The company conducts clinical trials for products like aXess, XABG, and Xplore, and has received significant investments and collaborations, including commitments from Grand Pharma and European funding. Xeltis's research demonstrates superior biocompatibility, reduced inflammation, and potential for long-term tissue regeneration, positioning it as a leader in regenerative cardiovascular medicine.

Industries

Health Care
Medical Device
Therapeutics
Medical Equipment Manufacturing

Nr. of Employees

small (1-50)

Xeltis

Eindhoven, North Brabant, Netherlands


Patents

Electrospun heart valves

US-12303384-B2

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System for producing a graft device with a three dimensional covering

US-12109759-B2

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System for producing a graft device with a three dimensional covering

US-12017413-B2

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Method of using a cardiovascular graft to reduce thrombosis or platelet adhesion

US-11980535-B2

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Medical device using bioabsorbable material

US-11872134-B2

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Medical implant preform produced using an inside out flipping method

US-11767613-B2

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Products

aXess

An implantable vascular graft designed for hemodialysis access that promotes endogenous tissue restoration, currently in pivotal clinical trials.

XABG

A synthetic coronary artery bypass graft that transforms into a living vessel, demonstrating unprecedented preclinical outcomes and in clinical trials.

Xplore 2

A pulmonary heart valve that leverages Xeltis' ETR platform to create living, durable valves for pediatric and adult patients.

aXess-S

Straight configuration of the aXess Hemodialysis Conduit with a 24 cm length.

aXess-L

Loop configuration of the aXess Hemodialysis Conduit with a 32 cm length.

XABG coronary artery bypass conduit

A novel coronary artery bypass conduit evaluated in first-in-human clinical studies.

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News & Updates

Xeltis successfully passes evaluation phase for €10million investment from European Innovation Council

Xeltis passes evaluation for a €10 million investment from the European Innovation Council, supporting clinical programs for its restorative devices.

Xeltis lands €15 million European financing from EIB

The European Investment Bank signs a €15 million financing agreement to support Xeltis' clinical development of its innovative cardiovascular devices.

Xeltis raises €32 million to drive clinical development of its advanced devices

A Series D2 funding round backed by international investors including DaVita Venture Group and EQT Life Sciences to accelerate clinical trials.

Xeltis’ aXess implanted in first patient in Poland

The first implantation of the aXess vascular graft in Poland as part of the pivotal trial for dialysis patients.

Preclinical outcomes for Xeltis’ CABG device may outperform saphenous veins

Preclinical data shows unprecedented one-year patency for XABG, potentially superior to saphenous veins, in large animal studies.

Xeltis’ bio-restorative technology published in Frontiers

Early outcomes from clinical trials demonstrating safety and performance of Xeltis' bio-restorative pulmonary valve.

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