System for producing a graft device with a three dimensional covering
Inventors
MANNARINO, Matthew • McGrath, Jon • LEESON, Cory • El-Kurdi, Mohammed • McDowell, Danielle • SANTIAGO, Kermit • Flaherty, J. Christopher
Assignees
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Publication Number
US-12017413-B2
Publication Date
2024-06-25
Expiration Date
Abstract
A system for producing a graft device for a patient may comprise: an imaging device configured to produce image data of a tubular conduit; and a processing unit configured to receive the image data from the imaging device. The processing unit may comprise an algorithm configured to process the image data, and produce a construction signal based on the image data. A material delivery device may be configured to receive the construction signal from the processor, and deliver material to produce a 3D covering based on the construction signal. The graft device may comprise the 3D covering positioned about the tubular conduit. Graft devices and methods of producing graft devices may also be provided.
Core Innovation
The invention discloses a system and workflow for producing a patient-specific graft device. A tubular conduit is imaged to obtain image data, and an algorithm generates a construction signal and an electronic 3D model. The construction signal is used to drive a material delivery device to fabricate a 3D covering positioned about the tubular conduit.
The 3D covering is customized to match discrete conduit features, including sidebranches and anastomosis end/bend features. Spatially varying properties of the 3D covering are generated from conduit-related data, including thickness and other coverage properties. The covering fabrication is described as optionally producing the covering directly or using a mandrel/target.
The patient-specific graft devices are described with examples including a coronary bypass graft and a dialysis graft. Imaging modalities and optional diagnostics/sensing and a user interface/model modification are also described. The workflow includes steps for image acquisition, 3D modeling, model modification, covering fabrication, and placement.
Claims Coverage
The independent claim set includes 1 independent claim. The claim defines a graft device with an electrospun tubular conduit and a 3D covering surrounding it, where at least one physical property of the 3D covering is defined by thickness data of the electrospun tubular conduit.
Electrospun tubular conduit and 3D covering defined by thickness data
The graft device comprises an electrospun tubular conduit and a 3D covering surrounding the electrospun tubular conduit, wherein at least one physical property of the 3D covering is defined by thickness data of the electrospun tubular conduit.
Overall, the claim coverage centers on defining physical properties of a 3D covering using thickness data from an electrospun tubular conduit.
Stated Advantages
Not explicitly described in patent.
Documented Applications
Not explicitly described in patent.
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