Slingshot Biosciences
Developer and supplier of non-biohazardous, synthetic lyophilized particle reference materials and associated digital tools for flow cytometry. Products reproduce cell-like scatter, autofluorescence, antigen density and fluorescence reporter signatures to support panel setup, spectral unmixing/compensation, immunophenotyping, instrument harmonization and quantitative antigen measurements. Maintains technical documentation, lot-specific certificates of analysis, application notes, webinars, and peer-reviewed publications to support adoption and multi-site standardization.
Industries
Nr. of Employees
medium (51-250)
Slingshot Biosciences
Patents
Size-tunable synthetic particles with tunable optical properties and methods for using the same for immune cell activation
US-12669427-B2
View DetailsEngineered particles as red blood cell mimics and compositions containing same for hematology
US-12379387-B2
View DetailsHydrogel particles as feeder cells and as synthetic antigen presenting cells
US-12312595-B2
View Details
Size-tunable synthetic particles with tunable optical properties and methods for using the same for immune cell activation
US-12669427-B2
View DetailsEngineered particles as red blood cell mimics and compositions containing same for hematology
US-12379387-B2
View DetailsHydrogel particles as feeder cells and as synthetic antigen presenting cells
US-12312595-B2
View DetailsProducts
Cell-mimic spectral reference controls
Particle-based single-stain controls designed to reproduce cellular autofluorescence and fluorescence intensities for spectral unmixing and compensation.
Viability and dual-dye compatibility controls
Lyophilized controls that mimic staining behavior for both DNA-intercalating viability dyes and amine-reactive viability dyes.
Scatter calibration hydrogel particles
Hydrogel reference particles with multiple defined scatter populations for aligning FSC/SSC and harmonizing settings across instruments.
Quantitative antigen-density kits
Kits containing multiple particle populations with defined antigen densities and a calculator to derive antigen-to-signal standard curves.
T-cell subset and activation/exhaustion mimic controls
Particle controls engineered to represent T cell memory subsets and activation/exhaustion marker combinations for T-cell enumeration and functional monitoring.
Single-vial amine-reactive viability control (single-vial cell-mimic)
A single-vial, lyophilized cell-mimic control designed to simplify viability staining workflows and reduce setup time for multicolor panels.
Cell-mimic spectral reference controls
Particle-based single-stain controls designed to reproduce cellular autofluorescence and fluorescence intensities for spectral unmixing and compensation.
Viability and dual-dye compatibility controls
Lyophilized controls that mimic staining behavior for both DNA-intercalating viability dyes and amine-reactive viability dyes.
Scatter calibration hydrogel particles
Hydrogel reference particles with multiple defined scatter populations for aligning FSC/SSC and harmonizing settings across instruments.
Quantitative antigen-density kits
Kits containing multiple particle populations with defined antigen densities and a calculator to derive antigen-to-signal standard curves.
T-cell subset and activation/exhaustion mimic controls
Particle controls engineered to represent T cell memory subsets and activation/exhaustion marker combinations for T-cell enumeration and functional monitoring.
Single-vial amine-reactive viability control (single-vial cell-mimic)
A single-vial, lyophilized cell-mimic control designed to simplify viability staining workflows and reduce setup time for multicolor panels.
Services
Custom engineering of particle-based controls to specified biomarkers, antigen densities and scatter properties for assay validation and harmonization.
Application support, webinars, technical data sheets, and training kits to assist with panel design, instrument setup and assay workflows.
Web-based spectra viewer and panel builder for planning multicolor flow cytometry experiments and evaluating spectral overlap.
Custom engineering of particle-based controls to specified biomarkers, antigen densities and scatter properties for assay validation and harmonization.
Application support, webinars, technical data sheets, and training kits to assist with panel design, instrument setup and assay workflows.
Web-based spectra viewer and panel builder for planning multicolor flow cytometry experiments and evaluating spectral overlap.
Expertise Areas
- Flow cytometry reference materials and controls
- Spectral unmixing and compensation workflows
- Immunophenotyping control development
- Quantitative antigen-density calibration
Key Technologies
- Lyophilization for reagent stabilization
- Hydrogel and polymer particle fabrication
- Incorporation of fluorescent reporters in reference particles
- Assigned antigen-density standardization
News & Updates
Company attendance at multiple cytometry and scientific meetings (examples listed for 2026–2027).
Peer-reviewed evaluation of a synthetic cell mimic used as an assay control for flow cytometry.
Comparison of synthetic controls to biological reference materials for TBNK immunophenotyping.
Published article examining polymer-based cell mimics as alternatives to PBMCs for robust immunophenotyping assay validation.
Framework for producing standardized, machine-readable reference datasets across instrument platforms.
Announcement of a single-vial, lyophilized cell-mimic viability control to accelerate flow cytometry workflows (Aug 2026).
Company attendance at multiple cytometry and scientific meetings (examples listed for 2026–2027).
Peer-reviewed evaluation of a synthetic cell mimic used as an assay control for flow cytometry.
Comparison of synthetic controls to biological reference materials for TBNK immunophenotyping.
Published article examining polymer-based cell mimics as alternatives to PBMCs for robust immunophenotyping assay validation.
Framework for producing standardized, machine-readable reference datasets across instrument platforms.
Announcement of a single-vial, lyophilized cell-mimic viability control to accelerate flow cytometry workflows (Aug 2026).